当前位置： SCI文献检索 > INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES期刊下所有文献 > Synthesis, characterization and cytocompatibility studies of α-chitin hydrogel/nano hydroxyapatite composite scaffolds.

Synthesis, characterization and cytocompatibility studies of α-chitin hydrogel/nano hydroxyapatite composite scaffolds.

Abstract：

:α-chitin hydrogel/nano hydroxyapatite (nHAp) composite scaffold have been synthesized by freeze-drying approach with nHAp and α-chitin hydrogel. The prepared nHAp and nanocomposite scaffolds were characterized using DLS, SEM, FT-IR, XRD and TGA studies. The porosity, swelling, degradation, protein adsorption and biomineralization (calcification) of the prepared nanocomposite scaffolds were evaluated. Cell viability, attachment and proliferation were investigated using MG 63, Vero, NIH 3T3 and nHDF cells to confirm that the nanocomposite scaffolds were cytocompatible and cells were found to attach and spread on the scaffolds. All the results suggested that these scaffolds can be used for bone and wound tissue engineering.

journal_name

Int J Biol Macromol

journal_title

International journal of biological macromolecules

authors

Kumar PT,Srinivasan S,Lakshmanan VK,Tamura H,Nair SV,Jayakumar R

doi

10.1016/j.ijbiomac.2011.03.006

subject

Has Abstract

pub_date

2011-07-01 00:00:00

pages

20-31

issue

1

eissn

0141-8130

issn

1879-0003

pii

S0141-8130(11)00097-3

journal_volume

49

pub_type

杂志文章

相关文献

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES文献大全
  • Microencapsulation of garlic oleoresin using maltodextrin as wall material by spray drying technology.

    abstract：:Experiments were conducted on microencapsulation of garlic oleoresin by spray drying with garlic oleoresin concentration (10%, 20% and 30%) as core material, maltodextrin concentration (40%, 50% and 60%) as wall material and inlet temperature of drying air (180 °C, 200 °C and 220 °C) as process parameters. The process...

    journal_title：International journal of biological macromolecules

    pub_type： 杂志文章

    doi：10.1016/j.ijbiomac.2014.08.011

    authors： Balasubramani P,Palaniswamy PT,Visvanathan R,Thirupathi V,Subbarayan A,Prakash Maran J

    更新日期：2015-01-01 00:00:00

  • Fabrication of a novel and ultrasensitive label-free electrochemical aptasensor for detection of biomarker prostate specific antigen.

    abstract：:In this study, a novel and efficient aptasensor based on immobilization of thiol terminated prostate specific antigen (PSA) binding DNA aptamer onto Au nanoparticles/fullerene C60-chitosan-ionic liquid/multiwalled carbon nanotubes/screen printed carbon electrode has been fabricated for ultrasensitive aptasensing of bi...

    journal_title：International journal of biological macromolecules

    pub_type： 杂志文章

    doi：10.1016/j.ijbiomac.2019.01.012

    authors： Jalalvand AR

    更新日期：2019-04-01 00:00:00

  • Antibacterial multilayer films fabricated by LBL immobilizing lysozyme and HTCC on nanofibrous mats.

    abstract：:Cellulose acetate nanofibrous mats were prepared by electrospunning technique. Positively charged and negatively charged composites were alternately deposited on negatively charged CA mats via layer-by-layer self-assembly technique. The morphology and inhibition rate of samples were investigated by regulating number o...

    journal_title：International journal of biological macromolecules

    pub_type： 杂志文章

    doi：10.1016/j.ijbiomac.2012.10.024

    authors： Huang W,Li X,Xue Y,Huang R,Deng H,Ma Z

    更新日期：2013-02-01 00:00:00

  • Chitosan and carboxymethyl cellulose based magnetic nanocomposites for application of peroxidase purification.

    abstract：:Recently, protein purification methods have a very wide area of research. Many of these methods are both expensive and multi-stage methods, that are needed in specific equipment. In this study, biopolymer coated magnetic nanoparticles, carboxymethyl cellulose (CMC) and chitosan (CH) coated Fe3O4 (magnetite) nanocompos...

    journal_title：International journal of biological macromolecules

    pub_type： 杂志文章

    doi：10.1016/j.ijbiomac.2016.12.042

    authors： Zengin Kurt B,Uckaya F,Durmus Z

    更新日期：2017-03-01 00:00:00

  • Exploration of DNA binding mode, chemical nuclease, cytotoxic and apoptotic potentials of diketone based oxovanadium(IV) complexes.

    abstract：:Two diketone based oxovanadium complexes, viz., bis(4,4,4-trifluoro-1-phenylbutane-1,3-dionato)oxovanadium(IV) (1) and bis(1,1,1-trifluoropentane-2,4-dionato)oxovanadium(IV) (2), have been synthesized and characterized by spectroscopic and analytical techniques. The DNA binding and the cleaving ability of the complexe...

    journal_title：International journal of biological macromolecules

    pub_type： 杂志文章

    doi：10.1016/j.ijbiomac.2015.02.027

    authors： Inamdar PR,Sheela A

    更新日期：2015-05-01 00:00:00

  • Effect of organic solvent on enzymatic degradation of cyclic PBS-based polymers by lipase N435.

    abstract：:Poly(butylene succinate-co-cyclohexane dimethanol succinate) (P(BS-co-CHDMS)) and poly(butylene succinate-co-butanediol cyclohexanedicarboxylic acid) (P(BS-co-BCHDA)) were catalytically degraded by Candida antarctica lipase Novozyme 435 (N435) in CHCl3 and THF. The results indicated that the degradation rate was P(BS-...

    journal_title：International journal of biological macromolecules

    pub_type： 杂志文章

    doi：10.1016/j.ijbiomac.2019.06.216

    authors： Li CT,Zhang M,Weng YX,Zhao D

    更新日期：2019-09-15 00:00:00

  • Structural basis of transport function in major facilitator superfamily protein from Trichoderma harzianum.

    abstract：:Trichothecenes are the sesquiterpenes secreted by Trichoderma spp. residing in the rhizosphere. These compounds have been reported to act as plant growth promoters and bio-control agents. The structural knowledge for the transporter proteins of their efflux remained limited. In this study, three-dimensional structure ...

    journal_title：International journal of biological macromolecules

    pub_type： 杂志文章

    doi：10.1016/j.ijbiomac.2016.10.099

    authors： Chaudhary N,Sandhu P,Ahmed M,Akhter Y

    更新日期：2017-02-01 00:00:00

  • Both beta sheet breaker and alpha helix forming pentapeptide inhibits protein fibrillation: Implication for the treatment of amyloid disorders.

    abstract：:For the first time, the effect of two novel designed pentapeptides on amyloid growth of human insulin using combined biophysical, microscopic, cell viability and computational approaches. Collective experimental data from ThT, ANS, and TEM demonstrate that in spite of having contrasting features, both peptides can eff...

    journal_title：International journal of biological macromolecules

    pub_type： 杂志文章

    doi：10.1016/j.ijbiomac.2019.11.222

    authors： Siddiqi MK,Majid N,Alam P,Malik S,Alam A,Rajan S,Ajmal MR,Khan RH

    更新日期：2020-01-15 00:00:00

  • Overcoming stemness and chemoresistance in colorectal cancer through miR-195-5p-modulated inhibition of notch signaling.

    abstract：:MiR-195-5p has been shown to have a regulatory role in a variety of cancers. Its influence on colorectal cancer (CRC), however, has never been evaluated. In the present study, we found that miR-195-5p expression was significantly decreased as compared to paired, tumor-adjacent normal colorectal tissues. We demonstrate...

    journal_title：International journal of biological macromolecules

    pub_type： 杂志文章

    doi：10.1016/j.ijbiomac.2018.05.151

    authors： Jin Y,Wang M,Hu H,Huang Q,Chen Y,Wang G

    更新日期：2018-10-01 00:00:00

  • d-Ribose induced glycoxidative insult to hemoglobin protein: An approach to spot its structural perturbations.

    abstract：:Glycation of biological macromolecule leads to the establishment of advanced glycation end products (AGEs) having implications in metabolic disorders. d‑ribose appears to be the most reactive among the naturally occurring sugars and contribute significantly to the glycation reactions in vivo, however, no report have b...

    journal_title：International journal of biological macromolecules

    pub_type： 杂志文章

    doi：10.1016/j.ijbiomac.2018.01.161

    authors： Siddiqui Z,Ishtikhar M,Moinuddin,Ahmad S

    更新日期：2018-06-01 00:00:00

  • 1,3,5-Triazine-2,4,6-tribenzaldehyde derivative as a new crosslinking agent for synthesis of pH-thermo dual responsive chitosan hydrogels and their nanocomposites: Swelling properties and drug release behavior.

    abstract：:In this work, 1,3,5-triazine-2,4,6-tribenzaldehyde was synthesized and chosen as the cross-linking agent for preparation of novel thermo- and pH-responsive hydrogels based on chitosan. The cross-linking proceeds through formation of imine bond by reaction of amino groups of chitosan with aldehyde groups of the cross-l...

    journal_title：International journal of biological macromolecules

    pub_type： 杂志文章

    doi：10.1016/j.ijbiomac.2017.07.128

    authors： Karimi AR,Tarighatjoo M,Nikravesh G

    更新日期：2017-12-01 00:00:00

  • Methods for preparation of low abundance glycoproteins from mammalian cell supernatants.

    abstract：:Proteins secreted to mammalian cell supernatants are usually in a low concentration and purity, due to the limitation of the expression systems or the presence of a large amount of contaminant proteins from the cell medium. So, initial protein recovery from cell supernatants requires of a highly specific chromatograph...

    journal_title：International journal of biological macromolecules

    pub_type： 杂志文章

    doi：10.1016/j.ijbiomac.2006.05.010

    authors： Ordoño D,Enjuanes L,Casasnovas JM

    更新日期：2006-08-15 00:00:00

  • Synthesis of Fe3O4@chitosan@ZIF-8 towards removal of malachite green from aqueous solution: Theoretical and experimental studies.

    abstract：:Discharges of dyes-containing wastewater from industries have created global concern. Removal of these substances from aqueous solution is very important and essential. Magnetic chitosan coated with ZIF-8 was prepared successfully and used to eliminate cationic dye malachite green in various conditions. To find the ef...

    journal_title：International journal of biological macromolecules

    pub_type： 杂志文章

    doi：10.1016/j.ijbiomac.2020.12.067

    authors： Zadvarzi SB,Khavarpour M,Vahdat SM,Baghbanian SM,Rad AS

    更新日期：2021-01-31 00:00:00

  • Protein structure preservation by MWCNTs/RTIL nano-composite.

    abstract：:The structure changes of hemoglobin (Hb) and glucose oxidase (GOx), as two typical proteins, upon interaction with MWCNTs and MWCNTs-[BMIM]BF₄(-) was studied. The ability of MWCNTs and MWCNTs-([BMIM]BF₄(-)) for the achievement of direct electrochemistry of GOx and Hb and enhancing the electron transfer rate between pr...

    journal_title：International journal of biological macromolecules

    pub_type： 杂志文章

    doi：10.1016/j.ijbiomac.2013.02.008

    authors： Karimi S,Ghourchian H,Banaei A

    更新日期：2013-05-01 00:00:00

  • Calcium-dependent conformational transition of calmodulin determined by Fourier transform infrared spectroscopy.

    abstract：:The Ca(2+)-induced conformational changes in calmodulin (CaM) were monitored by Fourier transform infrared spectroscopy (FT-IR) at different molar ratios of Ca(2+) to CaM. The results show that these changes occur in two distinctive transitions. The first transition involves significant changes in the overall secondar...

    journal_title：International journal of biological macromolecules

    pub_type： 杂志文章

    doi：10.1016/j.ijbiomac.2013.02.004

    authors： Yu T,Wu G,Yang H,Wang J,Yu S

    更新日期：2013-05-01 00:00:00

  • The role of Cys271 in conformational changes of arginine kinase.

    abstract：:Arginine kinase (AK), a crucial enzyme in energy metabolism, buffers cellular ATP levels by catalyzing the reversible phosphoryl transfer between ATP and arginine. To better understand the role of Cys271 in conformational changes of AK from greasyback shrimp (Metapenaeus ensis), we replaced the residue with serine and...

    journal_title：International journal of biological macromolecules

    pub_type： 杂志文章

    doi：10.1016/j.ijbiomac.2011.04.002

    authors： Liu N,Wang JS,Wang WD,Pan JC

    更新日期：2011-07-01 00:00:00

  • Chitosan-modified PLGA polymeric nanocarriers with better delivery potential for tamoxifen.

    abstract：:Breast cancer is believed as the second most common cause of cancer-related deaths in women for which tamoxifen is frequently prescribed. Despite many promises, tamoxifen is associated with various challenges like low hydrophilicity, poor bioavailability and dose-dependent toxicity. Therefore, it was envisioned to dev...

    journal_title：International journal of biological macromolecules

    pub_type： 杂志文章

    doi：10.1016/j.ijbiomac.2016.08.080

    authors： Thakur CK,Thotakura N,Kumar R,Kumar P,Singh B,Chitkara D,Raza K

    更新日期：2016-12-01 00:00:00

  • Kinetic regime of thermal aggregation of holo- and apoglycogen phosphorylases b.

    abstract：:To characterize the role of pyridoxal 5'-phosphate in stabilization of the conformation of muscle glycogen phosphorylase b (Phb), the mechanism of thermal aggregation for holo- and apoforms of Phb has been studied using dynamic light scattering. The order of aggregation with respect to the protein (n) for aggregation ...

    journal_title：International journal of biological macromolecules

    pub_type： 杂志文章

    doi：10.1016/j.ijbiomac.2016.08.038

    authors： Eronina TB,Mikhaylova VV,Chebotareva NA,Kurganov BI

    更新日期：2016-11-01 00:00:00

  • High selective purification of IgY from quail egg: Process design and quantification of deep eutectic solvent based ultrasound assisted liquid phase microextraction coupled with preparative chromatography.

    abstract：:The present research investigates on task-specific deep eutectic solvents (TDES) based aqueous two-phase extraction and purification of immunoglobulins by chromatography from quail egg. The synthesis of TDES was accomplished with quaternary ammonium salt as hydrogen bond acceptor (HBA) and glycerol as hydrogen bond do...

    journal_title：International journal of biological macromolecules

    pub_type： 杂志文章

    doi：10.1016/j.ijbiomac.2019.12.242

    authors： Balaraman HB,Rathnasamy SK

    更新日期：2020-03-01 00:00:00

  • Protective effects of sulfated chitooligosaccharides with different degrees of substitution in MIN6 cells.

    abstract：:Chitosan, a naturally occurring biopolymer, has received considerable attention for pharmaceutical applications due to its biocompatible, biodegradable and less toxic properties. In this study, sulfated chitooligosaccharides (COS-S) with different degrees of substitution (DS) were prepared to improve both its water-so...

    journal_title：International journal of biological macromolecules

    pub_type： 杂志文章

    doi：10.1016/j.ijbiomac.2012.09.032

    authors： Lu X,Guo H,Sun L,Zhang L,Zhang Y

    更新日期：2013-01-01 00:00:00

  • One pot preparation of magnetic chitosan-cystamine composites for selective recovery of Au(III) from the aqueous solution.

    abstract：:A novel magnetic chitosan adsorbent (CDF-CS) was synthesized by inserting magnetic particles into the crosslinked compound of chitosan (CS) and cystamine based on one-step method for selectively recovering Au(III) from aqueous solution. The characterization and adsorption mechanism of CDF-CS were studied by SEM-EDS, V...

    journal_title：International journal of biological macromolecules

    pub_type： 杂志文章

    doi：10.1016/j.ijbiomac.2019.07.022

    authors： Zhao M,Zhao J,Huang Z,Wang S,Zhang L

    更新日期：2019-09-15 00:00:00

  • Mechanical and biological properties of chitin/polylactide (PLA)/hydroxyapatite (HAP) composites cast using ionic liquid solutions.

    abstract：:This research investigates the potential development of lobster shell waste-derived chitin reinforced with poly(lactic acid) (PLA) and nano-hydroxyapatite (nHAP) into new materials with potentially superior mechanical and thermal properties for biomedical applications. The ionic liquid 1-ethyl-3-methylimidazolium acet...

    journal_title：International journal of biological macromolecules

    pub_type： 杂志文章

    doi：10.1016/j.ijbiomac.2019.10.168

    authors： Chakravarty J,Rabbi MF,Chalivendra V,Ferreira T,Brigham CJ

    更新日期：2020-05-15 00:00:00

  • Physicochemical characterization of polysaccharide from the leaf of Dendrobium officinale and effect on LPS induced damage in GES-1 cell.

    abstract：:The polysaccharide was first successfully isolated from the leaf of Dendrobium officinale by hot water extraction and alcohol precipitation and further purified using DEAE-52 and Sephadex G-100 chromatography. The structure of LDOP-1 was characterized by HPLC, GPC, and FT-IR and NMR spectroscopy, and its protective ef...

    journal_title：International journal of biological macromolecules

    pub_type： 杂志文章

    doi：10.1016/j.ijbiomac.2020.01.026

    authors： Yang K,Lu T,Zhan L,Zhou C,Zhang N,Lei S,Wang Y,Yang J,Yan M,Lv G,Chen S

    更新日期：2020-04-15 00:00:00

  • Synthesis, mechanical and thermal rheological properties of new gellan gum derivatives.

    abstract：:New derivatives of gellan gum (GG) were prepared by covalent attachment of octadecylamine (C18-NH2) to polysaccharide backbone via amide linkage by using bis(4-nitrophenyl) carbonate (4-NPBC) as a coupling agent. The effect of the alkyl chain grafted onto hydrophilic backbone of high molecular weight GG was investigat...

    journal_title：International journal of biological macromolecules

    pub_type： 杂志文章

    doi：10.1016/j.ijbiomac.2017.02.029

    authors： Agnello S,Gasperini L,Mano JF,Pitarresi G,Palumbo FS,Reis RL,Giammona G

    更新日期：2017-05-01 00:00:00

  • Antitumor and antimetastatic effects of PLA2-BthTX-II from Bothrops jararacussu venom on human breast cancer cells.

    abstract：:This work shows the antitumor and antimetastatic effects of BthTX-II, an Asp-49 PLA2 from Bothrops jararacussu venom, on MDA-MB-231 human triple negative breast cancer cells. BthTX-II caused a dose-dependent cell death of MDA-MB-231 cells when compared with the non-tumorigenic breast cells by inducing apoptosis and au...

    journal_title：International journal of biological macromolecules

    pub_type： 杂志文章

    doi：10.1016/j.ijbiomac.2019.05.164

    authors： de Vasconcelos Azevedo FVP,Zóia MAP,Lopes DS,Gimenes SN,Vecchi L,Alves PT,Rodrigues RS,Silva ACA,Yoneyama KAG,Goulart LR,de Melo Rodrigues V

    更新日期：2019-08-15 00:00:00

  • Characterization of a new endo-type alginate lyase from Vibrio sp. W13.

    abstract：:A gene, encoding a new alginate lyase Algb, was identified and cloned from marine bacterium Vibrio sp. W13. The recombinant alginate lyase was characterized followed by being purified on Ni-NTA Sepharose. It exhibited the highest activity (457 U/mg) at pH 8.0 and 30 °C. Interestingly, Algb possessed broader substrate ...

    journal_title：International journal of biological macromolecules

    pub_type： 杂志文章

    doi：10.1016/j.ijbiomac.2015.01.053

    authors： Zhu B,Tan H,Qin Y,Xu Q,Du Y,Yin H

    更新日期：2015-04-01 00:00:00

  • Hypoglycemic activity in vitro of polysaccharides from Camellia oleifera Abel. seed cake.

    abstract：:We isolated and purified polysaccharide from the Camellia oleifera Abel. seed cake (CCP) and studied its hypoglycemic activity in vitro. The molecular weight of CCP was 4736 Da and the monosaccharide molar composition ratio was: Xylose:Glucuronic acid:Galactosamine:Mannose = 10.9:4.4:2.6:1.8. The CCP contained conjuga...

    journal_title：International journal of biological macromolecules

    pub_type： 杂志文章

    doi：10.1016/j.ijbiomac.2018.04.054

    authors： Zhang S,Li X

    更新日期：2018-08-01 00:00:00

  • Preparation of a novel Grifola frondosa polysaccharide-chromium (III) complex and its hypoglycemic and hypolipidemic activities in high fat diet and streptozotocin-induced diabetic mice.

    abstract：:Polysaccharide from Grifola frondosa is one of the best metal-ion chelating agents because of its structural characteristics and excellent functional activities. In this study, we synthesized and characterized a novel Grifola frondosa polysaccharide-chromium (III) [GFP-Cr(III)] complex. Response surface methodology (R...

    journal_title：International journal of biological macromolecules

    pub_type： 杂志文章

    doi：10.1016/j.ijbiomac.2019.03.042

    authors： Guo WL,Shi FF,Li L,Xu JX,Chen M,Wu L,Hong JL,Qian M,Bai WD,Liu B,Zhang YY,Ni L,Rao PF,Lv XC

    更新日期：2019-06-15 00:00:00

  • Characterization of solvent stable extracellular protease from Bacillus koreensis (BK-P21A).

    abstract：:A total of 18 protease producing bacterial strains were isolated from detergent effluent in South Korea using skim milk agar medium. A strain (BK-P21A) was selected and identified as Bacillus koreensis based on morphological, biochemical and molecular characterizations (16S rRNA gene sequence analysis). Optimized cult...

    journal_title：International journal of biological macromolecules

    pub_type： 杂志文章

    doi：10.1016/j.ijbiomac.2013.02.014

    authors： Anbu P

    更新日期：2013-05-01 00:00:00

  • Exploration of the polar microenvironment around the reactive cysteine in rabbit muscle creatine kinase.

    abstract：:The polar microenvironment around the reactive Cys283 of rabbit muscle creatine kinase was explored using kinetic analysis of substrates reaction in the presence of modifiers. In the present study, three specific sulphydryl reagents, 5,5'-dithiobis(2-nitrobenzoic acid), 6,6'-dithiodinicotinic acid and 2,2'-dithiodipyr...

    journal_title：International journal of biological macromolecules

    pub_type： 杂志文章

    doi：10.1016/j.ijbiomac.2007.05.004

    authors： He HW,Li J,Zhao TJ,Ma Y,Shi F,Zhou HM

    更新日期：2007-10-01 00:00:00