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Synthesis, mechanical and thermal rheological properties of new gellan gum derivatives.

Abstract：

:New derivatives of gellan gum (GG) were prepared by covalent attachment of octadecylamine (C18-NH2) to polysaccharide backbone via amide linkage by using bis(4-nitrophenyl) carbonate (4-NPBC) as a coupling agent. The effect of the alkyl chain grafted onto hydrophilic backbone of high molecular weight GG was investigated in terms of physicochemical properties and ability of new derivatives to form hydrogels. A series of hydrogels was obtained in solutions with different kind and concentration of ions and their stability and mechanical properties were evaluated. The obtained derivatives resulted soluble at temperature lower than starting GG and physicochemical properties of obtained hydrogels suggested their potential use in biomedical field.

journal_name

Int J Biol Macromol

journal_title

International journal of biological macromolecules

authors

Agnello S,Gasperini L,Mano JF,Pitarresi G,Palumbo FS,Reis RL,Giammona G

doi

10.1016/j.ijbiomac.2017.02.029

subject

Has Abstract

pub_date

2017-05-01 00:00:00

pages

646-653

eissn

0141-8130

issn

1879-0003

pii

S0141-8130(16)32401-1

journal_volume

98

pub_type

杂志文章

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