Abstract:
:The chemical composition, structural features and bioactivities of chitosan derivatives were studied and reported here. Chitin and chitosan was extracted by chemical methods and yield was recorded 35% and 41%, moisture and ash has showed 7.4, 0.73, 1.2 and 0.79% and Ca was recorded high level (590 ppm). The IR spectrum has showed NH primary and secondary amines, OH group and several sugar stretching. N-acetyl glucosamine (GlcNAc), H-2 proton of glucosamine (GlcN), Anomeric protons, H-1 [GlcN (H-1D), GlcNAc (H-1A)] were noticed in 1H NMR and anomeric, methyl carbon atoms in 13C NMR. Rough surface, irregular block, crystalline with cluster and porosity structure was noticed by SEM observation. Antioxidant effect has showed good and concentration depended in four antioxidant assays. The α-amylase and β-glucosidase enzyme inhibition effect of chitosan has showed promising and dose depend also anticoagulant potential. Chitosan could be used in pharmaceutical industry and tissue engineering.
journal_name
Int J Biol Macromoljournal_title
International journal of biological macromoleculesauthors
Arasukumar B,Prabakaran G,Gunalan B,Moovendhan Mdoi
10.1016/j.ijbiomac.2019.06.033subject
Has Abstractpub_date
2019-08-15 00:00:00pages
1237-1245eissn
0141-8130issn
1879-0003pii
S0141-8130(19)33744-4journal_volume
135pub_type
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