Chemical composition, structural features, surface morphology and bioactivities of chitosan derivatives from lobster (Thenus unimaculatus) shells.

Abstract:

:The chemical composition, structural features and bioactivities of chitosan derivatives were studied and reported here. Chitin and chitosan was extracted by chemical methods and yield was recorded 35% and 41%, moisture and ash has showed 7.4, 0.73, 1.2 and 0.79% and Ca was recorded high level (590 ppm). The IR spectrum has showed NH primary and secondary amines, OH group and several sugar stretching. N-acetyl glucosamine (GlcNAc), H-2 proton of glucosamine (GlcN), Anomeric protons, H-1 [GlcN (H-1D), GlcNAc (H-1A)] were noticed in 1H NMR and anomeric, methyl carbon atoms in 13C NMR. Rough surface, irregular block, crystalline with cluster and porosity structure was noticed by SEM observation. Antioxidant effect has showed good and concentration depended in four antioxidant assays. The α-amylase and β-glucosidase enzyme inhibition effect of chitosan has showed promising and dose depend also anticoagulant potential. Chitosan could be used in pharmaceutical industry and tissue engineering.

journal_name

Int J Biol Macromol

authors

Arasukumar B,Prabakaran G,Gunalan B,Moovendhan M

doi

10.1016/j.ijbiomac.2019.06.033

subject

Has Abstract

pub_date

2019-08-15 00:00:00

pages

1237-1245

eissn

0141-8130

issn

1879-0003

pii

S0141-8130(19)33744-4

journal_volume

135

pub_type

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