Correlation between the effects of fosfomycin and chloramphenicol on Escherichia coli.

Abstract:

:It was speculated that the increase of the UDP-GlcNAc pool observed with chloramphenicol can modulate the residual PEP:UDP-GlcNAc-enolpyruvate activity of fosfomycin-treated cells. This provided an explanation on how chloramphenicol can insure the formation of enough UDP-MurNAc-pentapeptide to sustain peptidoglycan synthesis at a rate that will antagonize fosfomycin-induced lysis.

journal_name

FEMS Microbiol Lett

authors

Mengin-Lecreulx D,van Heijenoort J

doi

10.1016/0378-1097(90)90270-z

subject

Has Abstract

pub_date

1990-01-01 00:00:00

pages

129-33

issue

1-3

eissn

0378-1097

issn

1574-6968

journal_volume

54

pub_type

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