Severe sepsis: take care, take part.

abstract：AIM:To explore and detail clinical experiences of dabigatran, a novel anticoagulant, after it became available in New Zealand in July 2011. METHODS:A cohort of patients was recruited from Hutt Hospital and the two largest primary care practices in the Hutt Valley region. They were included if they took at least one do...

journal_title：Internal medicine journal

authors： Thorne K,Jayathissa S,Dee S,Briggs N,Taylor J,Reid S,De Silva K,Dean J

更新日期：2014-03-01 00:00:00

abstract：BACKGROUND:The comparative effectiveness of biologic treatment regimens in a real world Australian population is unknown. AIM:To assess the effectiveness of biological disease-modifying anti-rheumatic drugs (bDMARD) as monotherapy or in combination with methotrexate and/or other conventional DMARD (cDMARD) for the tre...

journal_title：Internal medicine journal

authors： Nicholls D,Barrett R,Button P,Truman M,Bird P,Roberts L,Tymms K,Littlejohn G,Griffiths H

更新日期：2018-10-01 00:00:00

abstract：:Mitochondrial DNA (mtDNA) haplogroups are 'neutral polymorphisms' in the mtDNA genome, which have accumulated and persisted along maternal lineages as the human population has migrated worldwide. Three ethnically distinct lineages of human mtDNA populations have been identified: European, characterized by nine haplogr...

journal_title：Internal medicine journal

authors： Manwaring N,Jones MM,Wang JJ,Rochtchina E,Mitchell P,Sue CM

更新日期：2006-08-01 00:00:00

abstract：BACKGROUND:Off-label use of rituximab in lupus nephritis is reported to be beneficial. While the optimal dose is unknown, the regimen of four intravenous doses of 375 mg/m(2) is commonly employed, despite expense and potential side-effects. AIM:To investigate the response to single-dose rituximab, added to standard co...

journal_title：Internal medicine journal

authors： Kotagiri P,Martin A,Hughes P,Becker G,Nicholls K

更新日期：2016-08-01 00:00:00

abstract：BACKGROUND:Despite the frequency of cannula-associated Staphylococcus aureus bacteraemia (CASAB) there is uncertainty regarding the duration of treatment required. AIM:To determine the relationship between the duration and type of treatment for CASAB and subsequent relapse with deep-seated S. aureus infection. METHOD...

journal_title：Internal medicine journal

authors： Thomas MG,Morris AJ

更新日期：2005-06-01 00:00:00

abstract：:Minimisation of radiation exposure with cardiac imaging reduces the potential of secondary side effects. Radiation exposure from myocardial perfusion scintigraphy and computed tomography coronary angiography (CTCA) was compared. Overall doses were low with both modalities. Doses were lower in the CTCA group, but by on...

journal_title：Internal medicine journal

authors： Tsay IM,Subiakto I,Asrar Ul Haq M,Castles AV,Allman K,Hayat U,Rudd N,Barlis P,van Gaal W

更新日期：2016-02-01 00:00:00

abstract：:Despite the increasing use and costs associated with external management consultancy for healthcare improvement, there is a paucity of formal evaluations examining impact. This paper aims to: (i) discuss the potential benefits and disadvantages of external consultancies in addressing complex healthcare challenges and ...

journal_title：Internal medicine journal

authors： Skouteris H,Kirkpatrick I,Currie G,Braithwaite J,Teede H

更新日期：2019-11-01 00:00:00

abstract：BACKGROUND:Both low-molecular-weight heparin (LMWH) and unfractionated heparin (UFH) have been shown to be equivalent in efficacy and safety profiles for the management of pulmonary embolism (PE). AIMS:To assess the real world management of anticoagulation in PE in a tertiary hospital setting. METHODS:An audit of pat...

journal_title：Internal medicine journal

authors： Khor YH,Smith R,McDonald CF

更新日期：2014-04-01 00:00:00

abstract：BACKGROUND/AIM:In patients discharged from an Older Person's Health hospital, we assessed (i) the prevalence of anticholinergic medications (ACM) in this study population and (ii) changes in anticholinergic drug burden during admission using the Anticholinergic Drug Scale (ADS). METHODS:Cases were identified between S...

journal_title：Internal medicine journal

authors： Lee MSS,Hanger HC

更新日期：2017-06-01 00:00:00

abstract：BACKGROUND/AIM:Although induction chemotherapy comprising high-dose cytarabine (HiDAC) in combination with idarubicin and etoposide or 'ICE' for adult acute myeloid leukaemia (AML) produces a complete remission rate of nearly 80%, gastrointestinal toxicity is significant. Omission of etoposide may produce similar clini...

journal_title：Internal medicine journal

authors： Low M,Lee D,Coutsouvelis J,Patil S,Opat S,Walker P,Schwarer A,Salem H,Avery S,Spencer A,Wei A

更新日期：2013-03-01 00:00:00

abstract：AIM:To ascertain the prevalence of HER2/neu-positive early breast cancer (EBC), utilisation of adjuvant trastuzumab and incidence of cardiac toxicity in a community private hospital setting. METHODS:Prospective data collected by breast oncologist and surgeons in all women diagnosed with EBC at the Mount Hospital (MH) ...

journal_title：Internal medicine journal

authors： Chan A,McGregor SR

更新日期：2012-03-01 00:00:00

abstract：BACKGROUND/AIM:Few studies have specifically investigated treatment of prednisolone-induced hyperglycaemia. AIM:To determine if a basal bolus insulin (BBI) protocol for inpatient hyperglycaemia is effective in patients prescribed acute prednisolone for an inflammatory disease. METHODS:In a cross-sectional study, 66 p...

journal_title：Internal medicine journal

authors： Burt MG,Drake SM,Aguilar-Loza NR,Esterman A,Stranks SN,Roberts GW

更新日期：2015-03-01 00:00:00

abstract：:Over the last 20 years, clinical medicine has witnessed rapid expansion in its underlying evidence base, greater demand for accountability in clinicians' use of limited resources and increasing societal expectation for health care that confers proven benefit at reasonable cost to all eligible recipients. Health servic...

journal_title：Internal medicine journal

authors： Scott I,Campbell D

更新日期：2002-03-01 00:00:00

abstract：:In Australia, mutations in epidermal growth factor mutations (EGFR) occur in 15% of patients diagnosed with non-small-cell lung cancer and are found with higher frequency in female, non-smokers of Asian ethnicity. Activating mutations in the EGFR gene are rarely described in SCLC. We present two cases of de novo EGFR ...

journal_title：Internal medicine journal

authors： Thai A,Chia PL,Russell PA,Do H,Dobrovic A,Mitchell P,John T

更新日期：2017-09-01 00:00:00

abstract：:The indication for permanent pacemaker remains controversial in malignant neurocardiogenic syncope. A highly reproducible prolonged pause during a repeat head-up tilt-table testing may identify a subgroup of neurally mediated syncope with a prominent and consistent cardioinhibitory component. Seven patients (3 females...

journal_title：Internal medicine journal

authors： Omar AR,Ng KS,Ng WL,Sutandar A

更新日期：2004-08-01 00:00:00

abstract：:Environmental exposures in the foetal period may predispose to autoimmunity. Aim of this study is to investigate whether seasonality in birth patterns exists in idiopathic inflammatory myopathies (IIM). We used Stata (StataCorp USA, version 13.0) and the user-written routine command 'circsummarise' to assess birth sea...

journal_title：Internal medicine journal

authors： Woodman R,Hakendorf P,Limaye V

更新日期：2016-05-01 00:00:00

abstract：:Heart failure remains an ultimately fatal condition that causes significant symptoms as it progresses. The involvement by palliative services in this patient group has been suboptimal despite many years of guidance from international cardiac societies who recommend a palliative focus for these patients. At Hutt hospit...

journal_title：Internal medicine journal

authors： Anscombe R,Middlemiss T

更新日期：2019-03-01 00:00:00

abstract：BACKGROUND:The international literature advocates for cancer screening in newly diagnosed patients with autoimmune myositis; however, there is no widely accepted consensus or guideline to outline the optimal cancer screening strategy and the evidence is currently insufficient to support any recommendation. AIM:Our stu...

journal_title：Internal medicine journal

authors： Dutton K,Soden M

更新日期：2017-12-01 00:00:00

abstract：AIMS:To evaluate the effectiveness of a new locality-based integrated diabetes care service for people with Type 2 diabetes in an inner regional area. METHODS:A quasi-experimental evaluation comparing baseline and follow up clinical data collected from general practices and specialist services participating in an inte...

journal_title：Internal medicine journal

authors： Zarora R,MacMillan F,Piya MK,Fernandes B,Simmons D

更新日期：2021-01-20 00:00:00

abstract：:Australian internal medicine trainees undergo intensive training in preparation for the Royal Australasian College of Physicians (RACP) clinical examination. Trainees preparing for the 2013 RACP clinical examination assessed the jugular venous pressure (JVP) of patients, with central venous pressure monitoring in the ...

journal_title：Internal medicine journal

authors： Sibbin CP,Bihari S,Russell P

更新日期：2016-09-01 00:00:00

abstract：:A retrospective review of patients receiving rituximab off label in a large teaching hospital was conducted between July 2002 and January 2006. The indication, dosing regimen, efficacy and cost of rituximab were evaluated. Rituximab was prescribed for three clinical indications; acute organ transplant rejection, post-...

journal_title：Internal medicine journal

authors： Sharma R,Koller L,Barclay P,Liddle C

更新日期：2007-08-01 00:00:00

abstract：:Bronchiectasis is generally classified into cystic fibrosis and non-cystic fibrosis bronchiectasis. This review article describes non-cystic fibrosis bronchiectasis in adults. Bronchiectasis can be considered a heterogeneous condition characterized by irreversible airway dilatation with chronic bronchial infection/inf...

journal_title：Internal medicine journal

authors： King P,Holdsworth S,Freezer N,Holmes P

更新日期：2006-11-01 00:00:00

abstract：BACKGROUND:Bali, Indonesia, presents significant infectious and non-infectious health risks for Australian travellers. Understanding this spectrum of illnesses has the potential to assist clinicians in evaluating unwell returning travellers and guide provision of pre-travel advice. AIM:To describe the spectrum of illn...

journal_title：Internal medicine journal

authors： Sohail A,McGuinness SL,Lightowler R,Leder K,Jomon B,Bain CA,Peleg AY

更新日期：2019-01-01 00:00:00

abstract：BACKGROUND:The risks are unknown for developing chronic gastrointestinal illness when personnel are relocated short term to other countries and when taking antibiotic prophylaxis in areas where malaria is endemic. AIM:To examine the associations of deployment to developed or developing countries and exposure to doxycy...

journal_title：Internal medicine journal

authors： Lee TW,Russell L,Deng M,Gibson PR

更新日期：2013-08-01 00:00:00

abstract：BACKGROUND:  Several cellular pathways are implicated in the pathogenesis of pulmonary arterial hypertension (PAH) and attempts to arrest disease progression with a single drug would not be expected to succeed in the medium term. In clinical practice, combination therapy is often used in patients deteriorating on monot...

journal_title：Internal medicine journal

authors： Keogh A,Strange G,Kotlyar E,Williams T,Kilpatrick D,Macdonald P,Brown K,Pidoux A,Kermeen F,Steele P,Dalton B,Gabbay E

更新日期：2011-03-01 00:00:00

abstract：BACKGROUND:The aim of the study was to assess the structural and functional effects of autologous stem cell transplantation (ASCT) on scleroderma finger clawing. METHODS:Using photocopies of hands of five scleroderma patients who underwent ASCT using photocopies of hands. Functional assessments used a standardized que...

journal_title：Internal medicine journal

authors： Englert H,Kirkham S,Moore J,Poon TS,Katelaris C,McGill N,Schrieber L,Manolios N

更新日期：2008-09-01 00:00:00

abstract：:Extramedullary haemopoiesis (EMH) is a complication commonly associated with beta-thalassaemia intermedia; it is frequently asymptomatic but can sometimes lead to symptomatic tumour-like masses. No guidelines or common consensus are available in literature regarding the different treatment strategies and only single c...

journal_title：Internal medicine journal

authors： Ruo Redda MG,Allis S,Reali A,Bartoncini S,Roggero S,Anglesio SM,Piga A

更新日期：2014-04-01 00:00:00

abstract：BACKGROUND:Tuberculous lymphadenitis is the commonest form of extrapulmonary tuberculosis. However, the optimal approach to diagnosis, employing biopsy by either fine needle aspiration (FNA) or surgical excision, remains uncertain. AIMS:To evaluate the diagnostic value of biopsy using each of the component diagnostic ...

journal_title：Internal medicine journal

authors： Knox J,Lane G,Wong JS,Trevan PG,Karunajeewa H

更新日期：2012-09-01 00:00:00

abstract：BACKGROUND:Trends in the incidence of acute myocardial infarction (AMI) provide important information for healthcare providers and can allow for accurate planning of future health needs and targeted interventions in areas with an excess burden of cardiovascular disease. AIM:To investigate the regional variations in AM...

journal_title：Internal medicine journal

authors： Davies AJ,Naudin C,Al-Omary M,Khan A,Oldmeadow C,Jones M,Bastian B,Bhagwandeen R,Fletcher P,Leitch J,Boyle A

更新日期：2017-05-01 00:00:00

abstract：BACKGROUND:Medical Emergency Teams (MET) have been developed to identify, review and manage acutely unwell ward patients. Previous studies have suggested that there may be obstacles to the utilization and activation of the MET. AIMS:To determine the effect of a detailed education programme on the rate of utilization o...

journal_title：Internal medicine journal

authors： Jones D,Bates S,Warrillow S,Goldsmith D,Kattula A,Way M,Gutteridge G,Buckmaster J,Bellomo R

更新日期：2006-04-01 00:00:00