Abstract:
:Bronchiectasis is generally classified into cystic fibrosis and non-cystic fibrosis bronchiectasis. This review article describes non-cystic fibrosis bronchiectasis in adults. Bronchiectasis can be considered a heterogeneous condition characterized by irreversible airway dilatation with chronic bronchial infection/inflammation. It remains a common condition and is a major cause of respiratory morbidity. Many factors are associated with bronchiectasis, but most commonly patients will have idiopathic disease. Important clinical findings include chronic productive cough, rhinosinusitis, fatigue and bi-basal crackles. Patients have usually had symptoms for many years. Diagnosis is confirmed by high-resolution computed tomography scanning using standardized criteria. Spirometry shows moderate airflow obstruction and there is a high prevalence of bronchial hyperreactivity. The most common pathogens are non-typeable Haemophilus influenzae and Pseudomonas aeruginosa. There may be considerable overlap with other chronic airway diseases. Treatment regimens are still not well defined. Patients tend to have ongoing symptoms and decline in respiratory function despite treatment.
journal_name
Intern Med Jjournal_title
Internal medicine journalauthors
King P,Holdsworth S,Freezer N,Holmes Pdoi
10.1111/j.1445-5994.2006.01219.xsubject
Has Abstractpub_date
2006-11-01 00:00:00pages
729-37issue
11eissn
1444-0903issn
1445-5994pii
IMJ1219journal_volume
36pub_type
杂志文章,评审abstract::Transient ischaemic attack (TIA) if untreated carries a high risk of early stroke and is associated with poorer long-term survival. There have been recent advances in the understanding of TIA, its investigations, management and organisation of services for patient care. Clinically, patients are diagnosed TIA if they h...
journal_title:Internal medicine journal
pub_type: 杂志文章,评审
doi:10.1111/imj.12059
更新日期:2013-04-01 00:00:00
abstract:BACKGROUND:In Australia medical practitioners are often required to assume the responsibility for assessing fitness to drive. However the clinical practice, knowledge and attitudes of doctors with regards to this responsibility are unknown. The aim of this study was to determine the clinical practice, knowledge and att...
journal_title:Internal medicine journal
pub_type: 杂志文章
doi:10.1111/j.1445-5994.2007.01337.x
更新日期:2007-06-01 00:00:00
abstract:AIM:To explore and detail clinical experiences of dabigatran, a novel anticoagulant, after it became available in New Zealand in July 2011. METHODS:A cohort of patients was recruited from Hutt Hospital and the two largest primary care practices in the Hutt Valley region. They were included if they took at least one do...
journal_title:Internal medicine journal
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1111/imj.12370
更新日期:2014-03-01 00:00:00
abstract:BACKGROUND:Management of acute ischaemic stroke is time critical. Reducing time to treatment with thrombolysis is strongly associated with improved outcomes in properly selected patients. However, there are barriers to ensuring timely treatment in the hospital setting. AIM:To determine if simple, no-cost protocol chan...
journal_title:Internal medicine journal
pub_type: 杂志文章
doi:10.1111/imj.14290
更新日期:2019-11-01 00:00:00
abstract::Postvenereal reactive arthritis is an inflammatory form of arthritis that commonly develops after urogenital infection, predominantly in human leucocyte antigen-B27-positive men in the third decade of life. In our hospital, patients underwent synovectomy before a 4-month course of antibiotics (ciprofloxacin, tetracycl...
journal_title:Internal medicine journal
pub_type: 杂志文章
doi:10.1111/imj.12580
更新日期:2014-12-01 00:00:00
abstract::Over the last 20 years, clinical medicine has witnessed rapid expansion in its underlying evidence base, greater demand for accountability in clinicians' use of limited resources and increasing societal expectation for health care that confers proven benefit at reasonable cost to all eligible recipients. Health servic...
journal_title:Internal medicine journal
pub_type: 杂志文章,评审
doi:
更新日期:2002-03-01 00:00:00
abstract:BACKGROUND:High inflammatory bowel disease (IBD) rates have been reported in Australasia, but no state-wide studies have yet been performed. AIM:This study estimates the 1-year incidence and point prevalence of IBD in the state of Tasmania, Australia. It also reports clinical outcomes after 12 months of diagnosis in a...
journal_title:Internal medicine journal
pub_type: 杂志文章
doi:10.1111/imj.14111
更新日期:2019-05-01 00:00:00
abstract::Depression, ischaemic heart disease and cerebrovascular disease are important causes of morbidity and are among the leading contributors to global health burden. These conditions often occur in the same patient, resulting in considerably greater effect on health than combinations of chronic diseases without depression...
journal_title:Internal medicine journal
pub_type: 杂志文章,评审
doi:10.1111/j.1445-5994.2008.01794.x
更新日期:2009-01-01 00:00:00
abstract:BACKGROUND:The Northern Territory (NT) has a long history of heavy alcohol consumption with a correspondingly high attributable morbidity and mortality. AIMS:We aimed to describe the number of admissions to Intensive Care associated with alcohol misuse. METHODS:Prospective case-control study including all admissions ...
journal_title:Internal medicine journal
pub_type: 杂志文章
doi:10.1111/imj.15212
更新日期:2021-01-19 00:00:00
abstract::(Neo)adjuvant chemotherapy for early stage breast cancer is associated with side-effects, resulting in increased emergency department (ED) presentations. Treatment-related toxicity can affect quality of life, compromise chemotherapy delivery and treatment outcomes, and increase healthcare use. We performed a retrospec...
journal_title:Internal medicine journal
pub_type: 杂志文章
doi:10.1111/imj.13785
更新日期:2018-05-01 00:00:00
abstract:BACKGROUND:Exacerbations requiring hospital admission for chronic obstructive pulmonary disease (COPD) contribute to a decline in health status and are costly to the community. Long-term trends in admissions and associated outcomes are difficult to establish because of frequent readmissions, high case fatality and pote...
journal_title:Internal medicine journal
pub_type: 杂志文章
doi:10.1111/j.1445-5994.2007.01240.x
更新日期:2007-02-01 00:00:00
abstract:BACKGROUND:Low socioeconomic status is associated with cardiovascular diseases, and an association with atrial fibrillation (AF) could guide screening. AIM:To investigate if indices of advantage/disadvantage (IAD), index of education/occupation (IEO) and index of economic resources were associated with incident AF, in...
journal_title:Internal medicine journal
pub_type: 杂志文章
doi:10.1111/imj.14214
更新日期:2019-10-01 00:00:00
abstract::In this essay, I reflect on my experience as a multiple sclerosis patient in order to identify some of the unique challenges that chronic disability poses in the physician-patient relationship. I suggest that it is important to broaden the goals of the clinical encounter to incorporate personal (as opposed to simply b...
journal_title:Internal medicine journal
pub_type: 杂志文章
doi:10.1111/j.1445-5994.2004.00700.x
更新日期:2004-11-01 00:00:00
abstract::Despite the increasing use and costs associated with external management consultancy for healthcare improvement, there is a paucity of formal evaluations examining impact. This paper aims to: (i) discuss the potential benefits and disadvantages of external consultancies in addressing complex healthcare challenges and ...
journal_title:Internal medicine journal
pub_type: 杂志文章
doi:10.1111/imj.14634
更新日期:2019-11-01 00:00:00
abstract:BACKGROUND:The parenteral administration of oestradiol acutely protects against exercise-induced myocardial ischaemia in women, but whether this effect is sex-specific is not known. AIMS:The effects of acutely administered conjugated equine oestrogen on exercise-induced myocardial ischaemia in men with established cor...
journal_title:Internal medicine journal
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1046/j.1445-5994.2003.00346.x
更新日期:2003-05-01 00:00:00
abstract::Healthcare encompasses multiple discourses to which health professionals, researchers, patients, carers and lay individuals contribute. Networks of patients and non-professionals often act collectively to build capacity, enhance access to resources, develop understanding and improve provision of care. This article exp...
journal_title:Internal medicine journal
pub_type: 历史文章,杂志文章
doi:10.1111/imj.14426
更新日期:2019-09-01 00:00:00
abstract::The prevalence of Helicobacter pylori in Western societies has rapidly declined, as reflected by the consistent decline in peptic ulcer disease. Nevertheless, there remains a cohort of the elderly population with a high prevalence of H. pylori infection. While the benefits of H. pylori eradication for H. pylori-associ...
journal_title:Internal medicine journal
pub_type: 杂志文章
doi:10.1046/j.1445-5994.2002.00275.x
更新日期:2002-09-01 00:00:00
abstract:BACKGROUND:Type 2 diabetes (T2D) in young adults is associated with a high risk of diabetes complications. AIMS:To investigated the demography and the emergence of complications of young adults with T2D in the central Auckland region where there has been substantial immigration. METHODS:In total, 310 young adults wit...
journal_title:Internal medicine journal
pub_type: 杂志文章
doi:10.1111/imj.13623
更新日期:2018-01-01 00:00:00
abstract::Interaction between doctors and the pharmaceutical industry is long-standing and ingrained in modern practice. Doctors-in-training are at a vulnerable stage of their careers, both in requiring knowledge and forming lasting relationships. There is evidence that limiting contact between industry and junior doctors has a...
journal_title:Internal medicine journal
pub_type: 杂志文章
doi:10.1111/imj.12855
更新日期:2015-10-01 00:00:00
abstract:BACKGROUND:Medical Emergency Teams (MET) have been developed to identify, review and manage acutely unwell ward patients. Previous studies have suggested that there may be obstacles to the utilization and activation of the MET. AIMS:To determine the effect of a detailed education programme on the rate of utilization o...
journal_title:Internal medicine journal
pub_type: 杂志文章
doi:10.1111/j.1445-5994.2006.01045.x
更新日期:2006-04-01 00:00:00
abstract:BACKGROUND:While treatment guidelines have been developed to guide the management of Staphylococcus aureus bacteraemia, there is a need to validate these guidelines in different clinical settings and to relate the effect of compliance to clinical outcome. AIMS:To assess the impact of adherence to treatment guidelines ...
journal_title:Internal medicine journal
pub_type: 杂志文章
doi:10.1046/j.1445-5994.2001.00205.x
更新日期:2002-05-01 00:00:00
abstract::A prospective study of non-invasive ventilation at The Prince Charles Hospital outside of the intensive care unit from March 2015 to March 2016 was performed. Overall 69 patients were included. Acute hypercapnic respiratory failure was the most common indication (n = 59; 85%). 49 (71%) had multifactorial respiratory f...
journal_title:Internal medicine journal
pub_type: 杂志文章
doi:10.1111/imj.13632
更新日期:2017-12-01 00:00:00
abstract::Many publications have highlighted a lack of practical competencies in recently qualified interns. Consultation between the University of Queensland and the Medical Education Unit at Redcliffe Hospital identified key areas where intervention could lead to greater work readiness, and the development of a complementary ...
journal_title:Internal medicine journal
pub_type: 杂志文章
doi:10.1111/j.1445-5994.2010.02272.x
更新日期:2010-10-01 00:00:00
abstract::Doctor-patient language discordance has been shown to lead to worse clinical outcomes. In this study of patients undergoing primary percutaneous coronary intervention for ST-elevation myocardial infarction at an Australian health service, we demonstrated that limited English proficiency (LEP) is an independent predict...
journal_title:Internal medicine journal
pub_type: 杂志文章
doi:10.1111/imj.13751
更新日期:2018-04-01 00:00:00
abstract::Clinician-performed chest ultrasound is rapidly entering clinical practice in the fields of intensive care, respiratory medicine and acute medicine. Ultrasound is clearly useful in the diagnosis and characterisation of pleural diseases. It is also critical in improving the safety of pleural interventions. More recentl...
journal_title:Internal medicine journal
pub_type: 杂志文章,评审
doi:10.1111/j.1445-5994.2012.02816.x
更新日期:2012-08-01 00:00:00
abstract:BACKGROUND:Physician trainees have elevated rates of psychological distress, mental disorders and suicide. Physician supervisors can support the mental health needs of trainees. AIM:To test the feasibility and acceptability of a tailored online mental health training program and ascertain the potential effectiveness o...
journal_title:Internal medicine journal
pub_type: 杂志文章
doi:10.1111/imj.15207
更新日期:2021-01-19 00:00:00
abstract:BACKGROUND:Neutropenic fever is a medical emergency, which poses a significant morbidity and mortality risk to cancer patients receiving chemotherapy. National guidelines recommend that patients presenting with suspected neutropenic fever receive appropriate intravenous antibiotics within 60 min of admission. AIM:We a...
journal_title:Internal medicine journal
pub_type: 杂志文章
doi:10.1111/imj.14464
更新日期:2020-08-01 00:00:00
abstract::Association between tumour necrosis alpha inhibitors and weight gain has been reported. We examined weight change in our cohort of inflammatory bowel disease patients treated with infliximab (IFX) for over 12 months, its associations and financial implications. Two-thirds of patients gained weight during the course of...
journal_title:Internal medicine journal
pub_type: 杂志文章
doi:10.1111/imj.14987
更新日期:2020-09-01 00:00:00
abstract::Minimisation of radiation exposure with cardiac imaging reduces the potential of secondary side effects. Radiation exposure from myocardial perfusion scintigraphy and computed tomography coronary angiography (CTCA) was compared. Overall doses were low with both modalities. Doses were lower in the CTCA group, but by on...
journal_title:Internal medicine journal
pub_type: 杂志文章
doi:10.1111/imj.12969
更新日期:2016-02-01 00:00:00
abstract:BACKGROUND:Prothrombinex-VF (a three-factor prothrombin complex concentrate) contains little factor VII. Therefore, the Warfarin Reversal Consensus Guidelines from 2004 published by The Australasian Society of Haemostasis and Thrombosis recommend that it be administered with fresh frozen plasma to reverse warfarin anti...
journal_title:Internal medicine journal
pub_type: 杂志文章
doi:10.1111/j.1445-5994.2010.02237.x
更新日期:2011-04-01 00:00:00