Suboptimal management of unfractionated heparin compared with low-molecular-weight heparin in the management of pulmonary embolism.

abstract：BACKGROUND:Cigarette smoking prevalence has been declining over decades in Western countries especially in higher socioeconomic groups. Employees of Australian hospitals span the socioeconomic spectrum, but there are few data on smoking prevalence from these workplaces. Because smoking is a health hazard, some argue th...

journal_title：Internal medicine journal

authors： Jones TE,Williams J

更新日期：2012-03-01 00:00:00

abstract：BACKGROUND:The association between weather and severe acute respiratory syndrome (SARS) transmission in Beijing and Hong Kong in the 2003 epidemic was studied to examine the effect of weather on SARS transmission. METHODS:Pearson's correlation analyses and negative binomial regression analyses were used to quantify th...

journal_title：Internal medicine journal

authors： Bi P,Wang J,Hiller JE

更新日期：2007-08-01 00:00:00

abstract：:Depression is the leading cause of non-fatal disease burden in Australia. Recently, increasing public recognition, together with the development of more integrated medical and psychological healthcare services has resulted in significant improvements. New pathophysiological models incorporate structural brain changes ...

journal_title：Internal medicine journal

authors： Hickie IB,Naismith SL,Norrie LM,Scott EM

更新日期：2009-11-01 00:00:00

abstract：:These consensus guidelines provide recommendations for the safe handling of monoclonal antibodies. Definitive recommendations are given for the minimum safe handling requirements to protect healthcare personnel. The seven recommendations cover: (i) appropriate determinants for evaluating occupational exposure risk; (i...

journal_title：Internal medicine journal

authors： Alexander M,King J,Bajel A,Doecke C,Fox P,Lingaratnam S,Mellor JD,Nicholson L,Roos I,Saunders T,Wilkes J,Zielinski R,Byrne J,MacMillan K,Mollo A,Kirsa S,Green M

更新日期：2014-10-01 00:00:00

abstract：BACKGROUND:The short Synacthen test is widely used to assess the hypothalamus pituitary adrenal axis in the outpatient setting. In the inpatient setting however, technical difficulties to adhere to the protocol may pose a challenge for using this test. AIMS:In this study we attempted to find the most suitable basal se...

journal_title：Internal medicine journal

authors： Tolkin L,Vidberg M,Munter G

更新日期：2020-08-24 00:00:00

abstract：BACKGROUND:Delirium is common in hospitalised patients but its epidemiology remains poorly characterised. AIMS:To test the hypothesis that patient demographics, clinical phenotype, management and outcomes of patient with delirium in hospital ward patients differ from intensive care unit (ICU) patients. METHODS:Retros...

journal_title：Internal medicine journal

authors： Canet E,Amjad S,Robbins R,Lewis J,Matalanis M,Jones D,Bellomo R

更新日期：2019-12-01 00:00:00

abstract：BACKGROUND:Off-label use of rituximab in lupus nephritis is reported to be beneficial. While the optimal dose is unknown, the regimen of four intravenous doses of 375 mg/m(2) is commonly employed, despite expense and potential side-effects. AIM:To investigate the response to single-dose rituximab, added to standard co...

journal_title：Internal medicine journal

authors： Kotagiri P,Martin A,Hughes P,Becker G,Nicholls K

更新日期：2016-08-01 00:00:00

abstract：:Conventional teaching on the mechanisms and treatment of spontaneous pneumothorax is either obviously wrong or based on a misunderstanding of the natural history of the condition. Spontaneous pneumothorax is a generally benign, self-limiting condition where conservative management should be considered. If intervention...

journal_title：Internal medicine journal

authors： Simpson G

更新日期：2010-03-01 00:00:00

abstract：BACKGROUND:While medications may prolong life and prevent morbidity in older people, adverse effects of polypharmacy are increasingly recognised. As patients age and become frail, prescribing may be expected to focus more on symptom control and minimise potentially harmful preventive medication use that confer little b...

journal_title：Internal medicine journal

authors： Ilango S,Pillans P,Peel NM,Scott I,Gray LC,Hubbard RE

更新日期：2017-09-01 00:00:00

abstract：BACKGROUND:Epidermal growth factor receptor (EGFR)-mutated non-small-cell lung cancer (NSCLC) is a subgroup of oncogene addicted lung cancer that predicts response to tyrosine kinase inhibitors (TKI). However, there is variability in response and survival outcomes in patients with EGFR mutation treated with TKI. AIM:T...

journal_title：Internal medicine journal

authors： Ding PN,Roberts TL,Chua W,Becker TM,Descallar J,Yip PY,Bray V

更新日期：2017-12-01 00:00:00

abstract：:Mitochondrial DNA (mtDNA) haplogroups are 'neutral polymorphisms' in the mtDNA genome, which have accumulated and persisted along maternal lineages as the human population has migrated worldwide. Three ethnically distinct lineages of human mtDNA populations have been identified: European, characterized by nine haplogr...

journal_title：Internal medicine journal

authors： Manwaring N,Jones MM,Wang JJ,Rochtchina E,Mitchell P,Sue CM

更新日期：2006-08-01 00:00:00

abstract：BACKGROUND:Management of acute ischaemic stroke is time critical. Reducing time to treatment with thrombolysis is strongly associated with improved outcomes in properly selected patients. However, there are barriers to ensuring timely treatment in the hospital setting. AIM:To determine if simple, no-cost protocol chan...

journal_title：Internal medicine journal

authors： Silsby M,Duma SR,Fois AF,Yin YWK,Koryzna J,Mahant N,Evans A,Fung VSC

更新日期：2019-11-01 00:00:00

abstract：BACKGROUND:Magnetic resonance angiography (MRA) of renal vessels correlates well with conventional angiography (CA) and enables non-invasive assessment of renal vessels without nephrotoxic contrast. AIMS:We aimed to identify the referral source and nature of the patient group undergoing renal MRA, and the impact of th...

journal_title：Internal medicine journal

authors： Prasad S,Bannister K,Taylor J

更新日期：2003-03-01 00:00:00

abstract：:We report the first published case of aggressive diffuse large B-cell (non-Hodgkin) lymphoma in a 35-year-old pregnant woman who had Crohn disease and was taking long-term thiopurine therapy: the patient developed placental insufficiency, and there was intrauterine fetal death. ...

journal_title：Internal medicine journal

authors： Chen G,Crispin P,Cherian M,Dahlstrom JE,Sethna FF,Kaye G,Pavli P,Subramaniam K

更新日期：2016-01-01 00:00:00

abstract：BACKGROUND:Exacerbations requiring hospital admission for chronic obstructive pulmonary disease (COPD) contribute to a decline in health status and are costly to the community. Long-term trends in admissions and associated outcomes are difficult to establish because of frequent readmissions, high case fatality and pote...

journal_title：Internal medicine journal

authors： Geelhoed EA,Brameld KJ,Holman CD,Thompson PJ

更新日期：2007-02-01 00:00:00

abstract：BACKGROUND:Despite the frequency of cannula-associated Staphylococcus aureus bacteraemia (CASAB) there is uncertainty regarding the duration of treatment required. AIM:To determine the relationship between the duration and type of treatment for CASAB and subsequent relapse with deep-seated S. aureus infection. METHOD...

journal_title：Internal medicine journal

authors： Thomas MG,Morris AJ

更新日期：2005-06-01 00:00:00

abstract：BACKGROUND:Infections and antibiotic resistance patterns in patients attending regional Australian cancer centres are poorly described. AIMS:To document patient characteristics, infection types, patterns of antibiotic resistance and outcomes in all patients with cancer requiring inpatient management for suspected infe...

journal_title：Internal medicine journal

authors： De Silva N,Jackson J,Steer C

更新日期：2018-03-01 00:00:00

abstract：BACKGROUND:A number of haematological malignancies can be cured by allogeneic stem cell transplantation but only approximately 30% of Australians have a suitable histocompatible related donor. Matched donors can be found on international registries of unrelated volunteers for a proportion of the remaining patients. For...

journal_title：Internal medicine journal

authors： Bradstock KF,Hertzberg MS,Kerridge IH,Svennilson J,McGurgan M,Huang G,Antonenas V,Gottlieb DJ

更新日期：2006-06-01 00:00:00

abstract：:Association between tumour necrosis alpha inhibitors and weight gain has been reported. We examined weight change in our cohort of inflammatory bowel disease patients treated with infliximab (IFX) for over 12 months, its associations and financial implications. Two-thirds of patients gained weight during the course of...

journal_title：Internal medicine journal

authors： Kaazan P,Tan Z,Bednarz J,Hughes J,Grafton R,Andrews JM

更新日期：2020-09-01 00:00:00

abstract：BACKGROUND:A Resuscitation Plan is a medically authorised order to use or withhold resuscitation interventions. Absence of appropriate resuscitation orders exposes patients to the risk of invasive medical interventions that may be of questionable benefit depending on individual circumstances. AIMS:To describe among ju...

journal_title：Internal medicine journal

authors： Bryant J,Waller A,Pickles R,Hullick C,Price E,White B,Willmott L,Bowman MA,Knight A,Ryall MA,Sanson-Fisher R

更新日期：2020-07-20 00:00:00

abstract：:Despite the increasing use and costs associated with external management consultancy for healthcare improvement, there is a paucity of formal evaluations examining impact. This paper aims to: (i) discuss the potential benefits and disadvantages of external consultancies in addressing complex healthcare challenges and ...

journal_title：Internal medicine journal

authors： Skouteris H,Kirkpatrick I,Currie G,Braithwaite J,Teede H

更新日期：2019-11-01 00:00:00

abstract：:Interaction between doctors and the pharmaceutical industry is long-standing and ingrained in modern practice. Doctors-in-training are at a vulnerable stage of their careers, both in requiring knowledge and forming lasting relationships. There is evidence that limiting contact between industry and junior doctors has a...

journal_title：Internal medicine journal

authors： Pokorny AM,Gittins CB

更新日期：2015-10-01 00:00:00

abstract：:Climate change is unequivocal. The fourth assessment report of the Intergovermental Panel on Climate Change has recently projected that global average surface temperature will increase by 1.1 to 6.4 degrees C by 2100. Anthropogenic warming during the twenty-first century would be much greater than that observed in the...

journal_title：Internal medicine journal

authors： Tong S,Mackenzie J,Pitman AJ,FitzGerald G,Nicholls N,Selvey L

更新日期：2008-06-01 00:00:00

abstract：:Myocardial perfusion imaging is a relatively new technique in the emergency department management of acute chest pain. With improved sensitivity and specificity compared to traditional methods of risk stratification, an abnormal scan rapidly identifies individuals with acute perfusion abnormalities and allows the appr...

journal_title：Internal medicine journal

authors： Knott JC,Better N

更新日期：2001-12-01 00:00:00

abstract：:Clarithromycin is the most documented cytochrome P450 3A4 (CYP3A4) inhibitor to cause an adverse interaction with simvastatin. This particular case is of interest as rhabdomyolysis only occurred after an increase in the dose of clarithromycin. The patient developed raised cardiac biomarkers without any obvious cardiac...

journal_title：Internal medicine journal

authors： Page SR,Yee KC

更新日期：2014-07-01 00:00:00

abstract：BACKGROUND:Low dose computed tomography (LDCT) screening can reduce lung cancer deaths in high risk individuals yet current Australian guidelines do not recommend screening. Little is known about current screening practices in Australia. METHODS:A survey was distributed to a nationally-representative sample of 4000 Au...

journal_title：Internal medicine journal

authors： Abeyweera PD,Brims FJH,Piccolo F,Lei C,Manners D

更新日期：2020-04-01 00:00:00

abstract：BACKGROUND:Glomerular M-type phospholipase A2 receptor (PLA2 R) is important for diagnosing idiopathic membranous nephropathy (IMN). The relation between glomerular PLA2 R expression and response to treatment remains to be explored. AIMS:We conducted the study to explore the positive rate and clinical significance of ...

journal_title：Internal medicine journal

authors： Liu H,Luo W,Gong S,Ding X

更新日期：2016-11-01 00:00:00

abstract：:It has been stated that academic medicine is in a worldwide crisis. Is this decline in hospital academic practice a predictable consequence of modern clinical practice with its emphasis on community and outpatient-based services as well as a corporate health-care ethos or does it relate to innate problems in the train...

journal_title：Internal medicine journal

authors： Wilson A

更新日期：2007-11-01 00:00:00

abstract：:As the mortality rate from breast cancer decreases, the issues facing breast cancer survivors are becoming increasingly important. Survivors of all ages may face physical and psychosocial consequences of their diagnosis and treatments. However, the long-term fertility and menopause-related side-effects of adjuvant the...

journal_title：Internal medicine journal

authors： Friedlander M,Thewes B

更新日期：2003-08-01 00:00:00

abstract：BACKGROUND:Management of adrenal incidentalomas (AI) is becoming more conservative, based on international data showing a low incidence of functional or malignant lesions. The clinical characteristics of AI in New Zealand are unknown. Therefore, whether the AI guidelines apply to the New Zealand population is also unkn...

journal_title：Internal medicine journal

authors： Goh Z,Phillips I,Hunt PJ,Soule S,Cawood TJ

更新日期：2018-02-01 00:00:00