Impact of the Mertz Glacier Tongue calving on dense water formation and export.

abstract：:The allotetraploid plant Nicotiana tabacum (common tobacco) is a major crop species and a model organism, for which only very fragmented genomic sequences are currently available. Here we report high-quality draft genomes for three main tobacco varieties. These genomes show both the low divergence of tobacco from its ...

journal_title：Nature communications

authors： Sierro N,Battey JN,Ouadi S,Bakaher N,Bovet L,Willig A,Goepfert S,Peitsch MC,Ivanov NV

更新日期：2014-05-08 00:00:00

abstract：:Bacterial infections and antibiotic resistance, particularly by Gram-negative pathogens, have become a global healthcare crisis. We report the design of a class of cationic antimicrobial polymers that cluster local facial amphiphilicity from repeating units to enhance interactions with bacterial membranes without requ...

journal_title：Nature communications

authors： Rahman MA,Bam M,Luat E,Jui MS,Ganewatta MS,Shokfai T,Nagarkatti M,Decho AW,Tang C

更新日期：2018-12-07 00:00:00

abstract：:The original version of this Article contained an error in Figure 4. In panel a, the colour code for hot and cold clusters was inadvertently inverted. In the correct version of panel a, the hot clusters are blue and the cold clusters are yellow. This error has now been corrected in both the PDF and HTML versions of th...

journal_title：Nature communications

authors： Chakravarthy A,Furness A,Joshi K,Ghorani E,Ford K,Ward MJ,King EV,Lechner M,Marafioti T,Quezada SA,Thomas GJ,Feber A,Fenton TR

更新日期：2018-11-02 00:00:00

abstract：:In the bottom-up synthesis of graphene nanoribbons (GNRs) from self-assembled linear polymer intermediates, surface-assisted cyclodehydrogenations usually take place on catalytic metal surfaces. Here we demonstrate the formation of GNRs from quasi-freestanding polymers assisted by hole injections from a scanning tunne...

journal_title：Nature communications

authors： Ma C,Xiao Z,Zhang H,Liang L,Huang J,Lu W,Sumpter BG,Hong K,Bernholc J,Li AP

更新日期：2017-03-13 00:00:00

abstract：:Radiotherapy is not currently informed by the genetic composition of an individual patient's tumour. To identify genetic features regulating survival after DNA damage, here we conduct large-scale profiling of cellular survival after exposure to radiation in a diverse collection of 533 genetically annotated human tumou...

journal_title：Nature communications

authors： Yard BD,Adams DJ,Chie EK,Tamayo P,Battaglia JS,Gopal P,Rogacki K,Pearson BE,Phillips J,Raymond DP,Pennell NA,Almeida F,Cheah JH,Clemons PA,Shamji A,Peacock CD,Schreiber SL,Hammerman PS,Abazeed ME

更新日期：2016-04-25 00:00:00

abstract：:Many phenomena occurring in strongly correlated quantum systems still await conclusive explanations. The absence of isolated free quarks in nature is an example. It is attributed to quark confinement, whose origin is not yet understood. The phase diagram for nuclear matter at general temperatures and densities, studie...

journal_title：Nature communications

authors： Tagliacozzo L,Celi A,Orland P,Mitchell MW,Lewenstein M

更新日期：2013-01-01 00:00:00

abstract：:Mutations in BLM in Bloom Syndrome patients predispose them to multiple types of cancers. Here we report that BLM is recruited in a biphasic manner to annotated DSBs. BLM recruitment is dependent on the presence of NBS1, MRE11 and ATM. While ATM activity is essential for BLM recruitment in early phase, it is dispensab...

journal_title：Nature communications

authors： Tripathi V,Agarwal H,Priya S,Batra H,Modi P,Pandey M,Saha D,Raghavan SC,Sengupta S

更新日期：2018-03-09 00:00:00

abstract：:The liver parenchyma is composed of hepatocytes and bile duct epithelial cells (BECs). Controversy exists regarding the cellular origin of human liver parenchymal tissue generation during embryonic development, homeostasis or repair. Here we report the existence of a hepatobiliary hybrid progenitor (HHyP) population i...

journal_title：Nature communications

authors： Segal JM,Kent D,Wesche DJ,Ng SS,Serra M,Oulès B,Kar G,Emerton G,Blackford SJI,Darmanis S,Miquel R,Luong TV,Yamamoto R,Bonham A,Jassem W,Heaton N,Vigilante A,King A,Sancho R,Teichmann S,Quake SR,Nakauchi H,Rash

更新日期：2019-07-26 00:00:00

abstract：:In response to intracellular signals in Gram--negative bacteria, translational riboswitches--commonly embedded in messenger RNAs (mRNAs)-regulate gene expression through inhibition of translation initiation. It is generally thought that this regulation originates from occlusion of the Shine-Dalgarno (SD) sequence upon...

journal_title：Nature communications

authors： Rinaldi AJ,Lund PE,Blanco MR,Walter NG

更新日期：2016-01-19 00:00:00

abstract：:Microelectromechanical systems (MEMS) enable many modern-day technologies, including actuators, motion sensors, drug delivery systems, projection displays, etc. Currently, MEMS fabrication techniques are primarily based on silicon micromachining processes, resulting in rigid and low aspect ratio structures. In this st...

journal_title：Nature communications

authors： Khudiyev T,Clayton J,Levy E,Chocat N,Gumennik A,Stolyarov AM,Joannopoulos J,Fink Y

更新日期：2017-11-10 00:00:00

abstract：:DOT1L has emerged as an anticancer target for MLL-associated leukaemias; however, its functional role in solid tumours is largely unknown. Here we identify that DOT1L cooperates with c-Myc and p300 acetyltransferase to epigenetically activate epithelial-mesenchymal transition (EMT) regulators in breast cancer progress...

journal_title：Nature communications

authors： Cho MH,Park JH,Choi HJ,Park MK,Won HY,Park YJ,Lee CH,Oh SH,Song YS,Kim HS,Oh YH,Lee JY,Kong G

更新日期：2015-07-22 00:00:00

abstract：:Under hypoxia, most of glucose is converted to secretory lactate, which leads to the overuse of glutamine-carbon. However, under such a condition how glutamine nitrogen is disposed to avoid over-accumulating ammonia remains to be determined. Here we identify a metabolic flux of glutamine to secretory dihydroorotate, w...

journal_title：Nature communications

authors： Wang Y,Bai C,Ruan Y,Liu M,Chu Q,Qiu L,Yang C,Li B

更新日期：2019-01-14 00:00:00

abstract：:The dynamical properties and mechanical functions of amorphous materials are governed by their microscopic structures, particularly the elasticity of the interaction networks, which is generally complicated by structural heterogeneity. This ubiquitous heterogeneous nature of amorphous materials is intriguingly attribu...

journal_title：Nature communications

authors： Yan L

更新日期：2018-04-10 00:00:00

abstract：:Many decisions are based on an internal model of the world. Yet, how such a model is constructed from experience and represented in memory remains unknown. We test the hypothesis that reward shapes memory for sequences of events by retroactively prioritizing memory for objects as a function of their distance from rewa...

journal_title：Nature communications

authors： Braun EK,Wimmer GE,Shohamy D

更新日期：2018-11-20 00:00:00

abstract：:OPCML, a tumor suppressor gene, is frequently silenced epigenetically in ovarian and other cancers. Here we report, by analysis of databases of tumor sequences, the observation of OPCML somatic missense mutations from various tumor types and the impact of these mutations on OPCML function, by solving the X-ray crystal...

journal_title：Nature communications

authors： Birtley JR,Alomary M,Zanini E,Antony J,Maben Z,Weaver GC,Von Arx C,Mura M,Marinho AT,Lu H,Morecroft EVN,Karali E,Chayen NE,Tate EW,Jurewicz M,Stern LJ,Recchi C,Gabra H

更新日期：2019-07-17 00:00:00

abstract：:Active biofluid management is central to the realization of wearable bioanalytical platforms that are poised to autonomously provide frequent, real-time, and accurate measures of biomarkers in epidermally-retrievable biofluids (e.g., sweat). Accordingly, here, a programmable epidermal microfluidic valving system is de...

journal_title：Nature communications

authors： Lin H,Tan J,Zhu J,Lin S,Zhao Y,Yu W,Hojaiji H,Wang B,Yang S,Cheng X,Wang Z,Tang E,Yeung C,Emaminejad S

更新日期：2020-09-02 00:00:00

abstract：:Topological defects in matter behave collectively to form highly non-trivial structures called topological textures that are characterised by conserved quantities such as the winding number. Here we show that an epitaxial ferroelectric square nanoplate of bismuth ferrite subjected to a large strain gradient (as much a...

journal_title：Nature communications

authors： Kim KE,Jeong S,Chu K,Lee JH,Kim GY,Xue F,Koo TY,Chen LQ,Choi SY,Ramesh R,Yang CH

更新日期：2018-01-26 00:00:00

abstract：:Determining nanoscale protein distribution via Photoactivated Localization Microscopy (PALM) mandates precise knowledge of the applied fluorophore's blinking properties to counteract overcounting artifacts that distort the resulting biomolecular distributions. Here, we present a readily applicable methodology to deter...

journal_title：Nature communications

authors： Platzer R,Rossboth BK,Schneider MC,Sevcsik E,Baumgart F,Stockinger H,Schütz GJ,Huppa JB,Brameshuber M

更新日期：2020-10-05 00:00:00

abstract：:Single-cell analysis reveals aspects of cellular physiology not evident from population-based studies, particularly in the case of highly multiplexed methods such as mass cytometry (CyTOF) able to correlate the levels of multiple signalling, differentiation and cell fate markers. Immunofluorescence (IF) microscopy add...

journal_title：Nature communications

authors： Lin JR,Fallahi-Sichani M,Sorger PK

更新日期：2015-09-24 00:00:00

abstract：:The inheritance of the centrosome during human fertilization remains mysterious. Here we show that the sperm centrosome contains, in addition to the known typical barrel-shaped centriole (the proximal centriole, PC), a surrounding matrix (pericentriolar material, PCM), and an atypical centriole (distal centriole, DC) ...

journal_title：Nature communications

authors： Fishman EL,Jo K,Nguyen QPH,Kong D,Royfman R,Cekic AR,Khanal S,Miller AL,Simerly C,Schatten G,Loncarek J,Mennella V,Avidor-Reiss T

更新日期：2018-06-07 00:00:00

abstract：:Molecules can efficiently and selectively convert light energy into other degrees of freedom. Disentangling the underlying ultrafast motion of electrons and nuclei of the photoexcited molecule presents a challenge to current spectroscopic approaches. Here we explore the photoexcited dynamics of molecules by an interac...

journal_title：Nature communications

authors： McFarland BK,Farrell JP,Miyabe S,Tarantelli F,Aguilar A,Berrah N,Bostedt C,Bozek JD,Bucksbaum PH,Castagna JC,Coffee RN,Cryan JP,Fang L,Feifel R,Gaffney KJ,Glownia JM,Martinez TJ,Mucke M,Murphy B,Natan A,Osipov T,

更新日期：2014-06-23 00:00:00

abstract：:Central spin decoherence caused by nuclear spin baths is often a critical issue in various quantum computing schemes, and it has also been used for sensing single-nuclear spins. Recent theoretical studies suggest that central spin decoherence can act as a probe of many-body physics in spin baths; however, identificati...

journal_title：Nature communications

authors： Ma WL,Wolfowicz G,Zhao N,Li SS,Morton JJ,Liu RB

更新日期：2014-09-10 00:00:00

abstract：:Electronic structure heterogeneities are ubiquitous in two-dimensional graphene and profoundly impact the transport properties of this material. Here we show the mapping of discrete electronic domains within a single graphene sheet using scanning transmission X-ray microscopy in conjunction with ab initio density func...

journal_title：Nature communications

authors： Schultz BJ,Patridge CJ,Lee V,Jaye C,Lysaght PS,Smith C,Barnett J,Fischer DA,Prendergast D,Banerjee S

更新日期：2011-06-28 00:00:00

abstract：:Genetic noise together with genome duplication and volume changes during cell cycle are significant contributors to cell-to-cell heterogeneity. How can cells buffer the effects of these unavoidable epigenetic and genetic variations on phenotypes that are sensitive to such variations? Here we show that a simple network...

journal_title：Nature communications

authors： Peng W,Song R,Acar M

更新日期：2016-10-03 00:00:00

abstract：:The overall survival of patients with acute myeloid leukemia (AML) is poor and identification of new disease-related therapeutic targets remains a major goal for this disease. Here we show that expression of MPP1, a PDZ-domain-containing protein, highly correlated with ABCC4 in AML, is associated with worse overall su...

journal_title：Nature communications

authors： Pitre A,Ge Y,Lin W,Wang Y,Fukuda Y,Temirov J,Phillips AH,Peters JL,Fan Y,Ma J,Nourse A,Sinha C,Lin H,Kriwacki R,Downing JR,Gruber TA,Centonze VE,Naren AP,Chen T,Schuetz JD

更新日期：2017-11-16 00:00:00

abstract：:Materials with switchable absorption properties have been widely used for smart window applications to reduce energy consumption and enhance occupant comfort in buildings. In this work, we combine the benefits of smart windows with energy conversion by producing a photovoltaic device with a switchable absorber layer t...

journal_title：Nature communications

authors： Wheeler LM,Moore DT,Ihly R,Stanton NJ,Miller EM,Tenent RC,Blackburn JL,Neale NR

更新日期：2017-11-23 00:00:00

abstract：:Multiphoton absorption processes enable many technologically important applications, such as in vivo imaging, photodynamic therapy and optical limiting, and so on. Specifically, higher-order nonlinear absorption such as five-photon absorption offers significant advantages of greater spatial confinement, increased pene...

journal_title：Nature communications

authors： Chen W,Bhaumik S,Veldhuis SA,Xing G,Xu Q,Grätzel M,Mhaisalkar S,Mathews N,Sum TC

更新日期：2017-05-12 00:00:00

abstract：:Van der Waals materials and their heterostructures offer a versatile platform for studying a variety of quantum transport phenomena due to their unique crystalline properties and the exceptional ability in tuning their electronic spectrum. However, most experiments are limited to devices that have lateral dimensions o...

journal_title：Nature communications

authors： Kumaravadivel P,Greenaway MT,Perello D,Berdyugin A,Birkbeck J,Wengraf J,Liu S,Edgar JH,Geim AK,Eaves L,Krishna Kumar R

更新日期：2019-07-26 00:00:00

abstract：:Deep subwavelength integration of high-definition plasmonic nanostructures is of key importance in the development of future optical nanocircuitry for high-speed communication, quantum computation and lab-on-a-chip applications. To date, the experimental realization of proposed extended plasmonic networks consisting o...

journal_title：Nature communications

authors： Huang JS,Callegari V,Geisler P,Brüning C,Kern J,Prangsma JC,Wu X,Feichtner T,Ziegler J,Weinmann P,Kamp M,Forchel A,Biagioni P,Sennhauser U,Hecht B

更新日期：2010-01-01 00:00:00

abstract：:γδ T cells are considered to be innate-like lymphocytes that respond rapidly to stress without clonal selection and differentiation. Here we use next-generation sequencing to probe how this paradigm relates to human Vδ2neg T cells, implicated in responses to viral infection and cancer. The prevalent Vδ1 T cell recepto...

journal_title：Nature communications

authors： Davey MS,Willcox CR,Joyce SP,Ladell K,Kasatskaya SA,McLaren JE,Hunter S,Salim M,Mohammed F,Price DA,Chudakov DM,Willcox BE

更新日期：2017-03-01 00:00:00