The tobacco genome sequence and its comparison with those of tomato and potato.

abstract：:One of the main reasons why nonlinear-optical signal processing (regeneration, logic, etc.) has not yet become a practical alternative to electronic processing is that the all-optical elements with nonlinear input-output relationship have remained inherently single-channel devices (just like their electronic counterpa...

journal_title：Nature communications

authors： Li L,Patki PG,Kwon YB,Stelmakh V,Campbell BD,Annamalai M,Lakoba TI,Vasilyev M

更新日期：2017-10-12 00:00:00

abstract：:Cognitive performance in people varies according to time-of-day, with memory retrieval declining in the late afternoon-early evening. However, functional roles of local brain circadian clocks in memory performance remains unclear. Here, we show that hippocampal clock controlled by the circadian-dependent transcription...

journal_title：Nature communications

authors： Hasegawa S,Fukushima H,Hosoda H,Serita T,Ishikawa R,Rokukawa T,Kawahara-Miki R,Zhang Y,Ohta M,Okada S,Tanimizu T,Josselyn SA,Frankland PW,Kida S

更新日期：2019-12-18 00:00:00

abstract：:Fusion proteins containing blue-light-activable protein domains possess great potential as molecular switches in cell signalling. This has recently been impressively demonstrated by connecting the light oxygen voltage LOV2-Jα-protein domain of A. sativa (AsLOV2-Jα) with the Rac1-GTPase, responsible for regulating the ...

journal_title：Nature communications

authors： Peter E,Dick B,Baeurle SA

更新日期：2010-11-16 00:00:00

abstract：:Amongst the many spectacular properties of hybrid lead halide perovskites, their defect tolerance is regarded as the key enabler for a spectrum of high-performance optoelectronic devices that propel perovskites to prominence. However, the plateauing efficiency enhancement of perovskite devices calls into question the ...

journal_title：Nature communications

authors： Righetto M,Lim SS,Giovanni D,Lim JWM,Zhang Q,Ramesh S,Tay YKE,Sum TC

更新日期：2020-06-01 00:00:00

abstract：:Combinatorial polyvalent contacts of histone-binding domains or readers commonly mediate localization and activities of chromatin-associated proteins. A pair of readers, the PHD fingers of the protein CHD4, has been shown to bivalently recognize histone H3 tails. Here we describe a mechanism by which these linked but ...

journal_title：Nature communications

authors： Gatchalian J,Wang X,Ikebe J,Cox KL,Tencer AH,Zhang Y,Burge NL,Di L,Gibson MD,Musselman CA,Poirier MG,Kono H,Hayes JJ,Kutateladze TG

更新日期：2017-11-14 00:00:00

abstract：:Azobenzene, a versatile and polymorphic molecule, has been extensively and successfully used for photoswitching applications. The debate over its photoisomerization mechanism leveraged on the computational scrutiny with ever-increasing levels of theory. However, the most resolved absorption spectrum for the transition...

journal_title：Nature communications

authors： Tan EM,Amirjalayer S,Smolarek S,Vdovin A,Zerbetto F,Buma WJ

更新日期：2015-01-06 00:00:00

abstract：:Insulin regulates glycaemia, lipogenesis and increases mRNA translation. Cells with reduced eukaryotic initiation factor 6 (eIF6) do not increase translation in response to insulin. The role of insulin-regulated translation is unknown. Here we show that reduction of insulin-regulated translation in mice heterozygous f...

journal_title：Nature communications

authors： Brina D,Miluzio A,Ricciardi S,Clarke K,Davidsen PK,Viero G,Tebaldi T,Offenhäuser N,Rozman J,Rathkolb B,Neschen S,Klingenspor M,Wolf E,Gailus-Durner V,Fuchs H,Hrabe de Angelis M,Quattrone A,Falciani F,Biffo S

更新日期：2015-09-18 00:00:00

abstract：:A reliable method for recording evoked synaptic events in identified neurons in Caenorhabditis elegans would greatly accelerate our understanding of its nervous system at the molecular, cellular and network levels. Here we describe a method for recording synaptic currents and potentials from identified neurons in near...

journal_title：Nature communications

authors： Lindsay TH,Thiele TR,Lockery SR

更新日期：2011-01-01 00:00:00

abstract：:Optimal decision-making employs short-term rewards and abstract long-term information based on which of these is deemed relevant. Employing short- vs. long-term information is associated with different learning mechanisms, yet neural evidence showing that these two are dissociable is lacking. Here we demonstrate that ...

journal_title：Nature communications

authors： Fischer AG,Bourgeois-Gironde S,Ullsperger M

更新日期：2017-11-22 00:00:00

abstract：:Considerable progress in the fabrication of quasicrystals demonstrates that they can be realized in a broad range of materials. However, the development of chemistries enabling direct experimental observation of early quasicrystal growth pathways remains challenging. Here, we report the synthesis of four surfactant-di...

journal_title：Nature communications

authors： Sun Y,Ma K,Kao T,Spoth KA,Sai H,Zhang D,Kourkoutis LF,Elser V,Wiesner U

更新日期：2017-08-15 00:00:00

abstract：:As influenza A viruses remain a major threat to human health worldwide, the discovery of broadly neutralizing monoclonal antibodies that recognize conserved epitopes would facilitate the development of antibody-based therapeutic strategies. Here we report that a VH4-4-encoded human mAb named 3E1 could neutralize H1 an...

journal_title：Nature communications

authors： Wang W,Sun X,Li Y,Su J,Ling Z,Zhang T,Wang F,Zhang H,Chen H,Ding J,Sun B

更新日期：2016-12-02 00:00:00

abstract：:One-fourth of Plasmodium falciparum proteins have asparagine repeats that increase the propensity for aggregation, especially at elevated temperatures that occur routinely in malaria-infected patients. Here we report that a Plasmodium Asn repeat-containing protein (PFI1155w) formed aggregates in mammalian cells at feb...

journal_title：Nature communications

authors： Muralidharan V,Oksman A,Pal P,Lindquist S,Goldberg DE

更新日期：2012-01-01 00:00:00

abstract：:The magnetostructural coupling between the structural and the magnetic transition has a crucial role in magnetoresponsive effects in a martensitic-transition system. A combination of various magnetoresponsive effects based on this coupling may facilitate the multifunctional applications of a host material. Here we dem...

journal_title：Nature communications

authors： Liu E,Wang W,Feng L,Zhu W,Li G,Chen J,Zhang H,Wu G,Jiang C,Xu H,de Boer F

更新日期：2012-05-29 00:00:00

abstract：:The original version of this Article contained errors in Figures 1 and 3. In Fig. 1b, the label 'IP-PBP3' above the second of the three blots incorrectly read 'IP-PBP1B'. In Fig. 3b, the label 'PBP1B' under the first bar of each chart incorrectly read 'PBP1A'. These errors have been corrected in both the PDF and HTML ...

journal_title：Nature communications

authors： Pazos M,Peters K,Casanova M,Palacios P,VanNieuwenhze M,Breukink E,Vicente M,Vollmer W

更新日期：2019-01-30 00:00:00

abstract：:Rapid growth in size and complexity of biological data sets has led to the 'Big Data to Knowledge' challenge. We develop advanced data integration methods for multi-level analysis of genomic, transcriptomic, ribosomal profiling, proteomic and fluxomic data. First, we show that pairwise integration of primary omics dat...

journal_title：Nature communications

authors： Ebrahim A,Brunk E,Tan J,O'Brien EJ,Kim D,Szubin R,Lerman JA,Lechner A,Sastry A,Bordbar A,Feist AM,Palsson BO

更新日期：2016-10-26 00:00:00

abstract：:The recent levelling of global mean temperatures after the late 1990s, the so-called global warming hiatus or slowdown, ignited a surge of scientific interest into natural global mean surface temperature variability, observed temperature biases, and climate communication, but many questions remain about how these find...

journal_title：Nature communications

authors： Johnson NC,Xie SP,Kosaka Y,Li X

更新日期：2018-04-30 00:00:00

abstract：:Understanding the structural biology of the insulin receptor and how it signals is of key importance in the development of insulin analogs to treat diabetes. We report here a cryo-electron microscopy structure of a single insulin bound to a physiologically relevant, high-affinity version of the receptor ectodomain, th...

journal_title：Nature communications

authors： Weis F,Menting JG,Margetts MB,Chan SJ,Xu Y,Tennagels N,Wohlfart P,Langer T,Müller CW,Dreyer MK,Lawrence MC

更新日期：2018-10-24 00:00:00

abstract：:Synthesis of ethanol from non-petroleum carbon resources via syngas (a mixture of H2 and CO) is an important but challenging research target. The current conversion of syngas to ethanol suffers from low selectivity or multiple processes with high energy consumption. Here, we report a high-selective conversion of synga...

journal_title：Nature communications

authors： Kang J,He S,Zhou W,Shen Z,Li Y,Chen M,Zhang Q,Wang Y

更新日期：2020-02-11 00:00:00

abstract：:Trimethylation of histone H3 on lysine-4 (H3K4me3) is associated with gene-regulatory elements, but its transcription-independent function in cell division is unclear. CxxC-finger protein-1 (CFP1) is a major mediator of H3K4 trimethylation in mouse oocytes. Here we report that oocyte-specific knockout of Cxxc1, inhibi...

journal_title：Nature communications

authors： Sha QQ,Dai XX,Jiang JC,Yu C,Jiang Y,Liu J,Ou XH,Zhang SY,Fan HY

更新日期：2018-08-28 00:00:00

abstract：:The development of stimulus-responsive polymeric materials is of great importance, especially for the development of remotely manipulated materials not in direct contact with an actuator. Here we design a photoresponsive supramolecular actuator by integrating host-guest interactions and photoswitching ability in a hyd...

journal_title：Nature communications

authors： Takashima Y,Hatanaka S,Otsubo M,Nakahata M,Kakuta T,Hashidzume A,Yamaguchi H,Harada A

更新日期：2012-01-01 00:00:00

abstract：:The ontogeny of haematopoietic niches in vertebrates is essentially unknown. Here we show that the stromal cells of the caudal haematopoietic tissue (CHT), the first niche where definitive haematopoietic stem/progenitor cells (HSPCs) home in zebrafish development, derive from the caudal somites through an epithelial-m...

journal_title：Nature communications

authors： Murayama E,Sarris M,Redd M,Le Guyader D,Vivier C,Horsley W,Trede N,Herbomel P

更新日期：2015-09-28 00:00:00

abstract：:Increasing evidence suggests that neural population responses have their own internal drive, or dynamics, that describe how the neural population evolves through time. An important prediction of neural dynamical models is that previously observed neural activity is informative of noisy yet-to-be-observed activity on s...

journal_title：Nature communications

authors： Kao JC,Nuyujukian P,Ryu SI,Churchland MM,Cunningham JP,Shenoy KV

更新日期：2015-07-29 00:00:00

abstract：:Incorporating oxophilic metals into noble metal-based catalysts represents an emerging strategy to improve the catalytic performance of electrocatalysts in fuel cells. However, effects of the distance between the noble metal and oxophilic metal active sites on the catalytic performance have rarely been investigated. H...

journal_title：Nature communications

authors： Chen L,Lu L,Zhu H,Chen Y,Huang Y,Li Y,Wang L

更新日期：2017-01-10 00:00:00

abstract：:Adult-type granulosa cell tumors of the ovary (aGCTs) are rare gynecologic malignancies that exhibit a high frequency of somatic FOXL2 c.C402G (p.Cys134Trp) mutation. Treatment of relapsed aGCT remains a significant clinical challenge. Here we show, using whole-exome and cancer gene panel sequencing of 79 aGCTs from t...

journal_title：Nature communications

authors： Hillman RT,Celestino J,Terranova C,Beird HC,Gumbs C,Little L,Nguyen T,Thornton R,Tippen S,Zhang J,Lu KH,Gershenson DM,Rai K,Broaddus RR,Futreal PA

更新日期：2018-06-27 00:00:00

abstract：:The development of malaria parasites throughout their various life cycle stages is coordinated by changes in gene expression. We previously showed that the three-dimensional organization of the Plasmodium falciparum genome is strongly associated with gene expression during its replication cycle inside red blood cells....

journal_title：Nature communications

authors： Bunnik EM,Cook KB,Varoquaux N,Batugedara G,Prudhomme J,Cort A,Shi L,Andolina C,Ross LS,Brady D,Fidock DA,Nosten F,Tewari R,Sinnis P,Ay F,Vert JP,Noble WS,Le Roch KG

更新日期：2018-05-15 00:00:00

abstract：:Kilonovae produced by the coalescence of compact binaries with at least one neutron star are promising standard sirens for an independent measurement of the Hubble constant (H0). Through their detection via follow-up of gravitational-wave (GW), short gamma-ray bursts (sGRBs) or optical surveys, a large sample of kilon...

journal_title：Nature communications

authors： Coughlin MW,Antier S,Dietrich T,Foley RJ,Heinzel J,Bulla M,Christensen N,Coulter DA,Issa L,Khetan N

更新日期：2020-08-17 00:00:00

abstract：:Perovskite solar cells have received worldwide interests due to swiftly improved efficiency but the poor stability of the perovskite component hampers the device fabrication under normal condition. Herein, we develop a reliable nonstoichiometric acid-base reaction route to stable perovskite films by intermediate chemi...

journal_title：Nature communications

authors： Long M,Zhang T,Chai Y,Ng CF,Mak TC,Xu J,Yan K

更新日期：2016-11-15 00:00:00

abstract：:DNA is a promising molecule for applications in molecular electronics because of its unique electronic and self-assembly properties. Here we report that the conductance of DNA duplexes increases by approximately one order of magnitude when its conformation is changed from the B-form to the A-form. This large conductan...

journal_title：Nature communications

authors： Artés JM,Li Y,Qi J,Anantram MP,Hihath J

更新日期：2015-12-09 00:00:00

abstract：:It is difficult to achieve minimally invasive injectable cell delivery while maintaining high cell retention and animal survival for in vivo stem cell therapy of myocardial infarction. Here we show that pluripotent stem cell aggregates pre-differentiated into the early cardiac lineage and encapsulated in a biocompatib...

journal_title：Nature communications

authors： Zhao S,Xu Z,Wang H,Reese BE,Gushchina LV,Jiang M,Agarwal P,Xu J,Zhang M,Shen R,Liu Z,Weisleder N,He X

更新日期：2016-10-27 00:00:00

abstract：:The liquid and glass states of metal-organic frameworks (MOFs) have recently become of interest due to the potential for liquid-phase separations and ion transport, alongside the fundamental nature of the latter as a new, fourth category of melt-quenched glass. Here we show that the MOF liquid state can be blended wit...

journal_title：Nature communications

authors： Longley L,Collins SM,Zhou C,Smales GJ,Norman SE,Brownbill NJ,Ashling CW,Chater PA,Tovey R,Schönlieb CB,Headen TF,Terrill NJ,Yue Y,Smith AJ,Blanc F,Keen DA,Midgley PA,Bennett TD

更新日期：2018-06-15 00:00:00