The dependence of the Yersinia pestis capsule on pathogenesis is influenced by the mouse background.

abstract：:Gamma interferon (IFN-gamma)-activated macrophages use an alternative processing mechanism to present Salmonella antigens to CD8(+) T lymphocytes. This pathway involves processing of antigen in a vacuolar compartment followed by secretion and loading of antigenic peptides to major histocompatibility complex class I (M...

journal_title：Infection and immunity

authors： Rosales-Reyes R,Alpuche-Aranda C,Ramírez-Aguilar Mde L,Castro-Eguiluz AD,Ortiz-Navarrete V

更新日期：2005-07-01 00:00:00

abstract：:Borrelia burgdorferi produces a mitogen for murine B lymphocytes which can be measured in vitro by polyclonal stimulation of proliferation and immunoglobulin production (R. Schoenfeld, B. Araneo, Y. Ma, L. Yang, and J. J. Weis, Infect. Immun. 60:455-464, 1992). Sonicated B. burgdorferi cells also stimulated IL-6 produ...

journal_title：Infection and immunity

authors： Yang L,Ma Y,Schoenfeld R,Griffiths M,Eichwald E,Araneo B,Weis JJ

更新日期：1992-08-01 00:00:00

abstract：:Chronic actinomycetoma associated with grain production was induced in BALB/c mice by subcutaneous inoculation of live Nocardia brasiliensis in Freund incomplete adjuvant into the hind footpads. Similar inoculation of N. asteroides and N. caviae resulted in local tumor formation which healed spontaneously after 5 mont...

journal_title：Infection and immunity

authors： Zlotnik H,Buckley HR

更新日期：1980-09-01 00:00:00

abstract：:Dendritic cells (DC) suffer a maturation defect following interaction with erythrocytes infected with malaria parasites and become unable to induce protective malaria liver-stage immunity. Here we show that, by contrast, maturation-arrested DC in vitro are capable of the successful induction of antigen-specific gamma ...

journal_title：Infection and immunity

authors： Pouniotis DS,Proudfoot O,Bogdanoska V,Apostolopoulos V,Fifis T,Plebanski M

更新日期：2004-09-01 00:00:00

abstract：:The innate and the adaptive arms of the mucosal immune system must be coordinated to facilitate the control of pathogenic invasion while maintaining immune homeostasis. Toll-like receptors, able to activate the cell to produce bactericidal and inflammatory cytokines but also able to upregulate antigen (Ag)-presenting ...

journal_title：Infection and immunity

authors： Muthukuru M,Cutler CW

更新日期：2008-02-01 00:00:00

abstract：:Pertussis is a severe respiratory disease caused by Bordetella pertussis The classic symptoms of pertussis include paroxysmal coughing with an inspiratory whoop, posttussive vomiting, cyanosis, and persistent coryzal symptoms. Infants under 2 months of age experience more severe disease, with most deaths occurring in ...

journal_title：Infection and immunity

authors： Zimmerman LI,Papin JF,Warfel J,Wolf RF,Kosanke SD,Merkel TJ

更新日期：2018-10-25 00:00:00

abstract：:The Salmonella typhimurium gene for Mn-cofactored superoxide dismutase (sodA) was cloned by complementation of an Escherichia coli sodA sodB mutant for growth on minimal medium. Sequence analysis revealed an open reading frame of 618 bp encoding a polypeptide with 97% identity to E. coli SodA. A S. typhimurium sodA mu...

journal_title：Infection and immunity

authors： Tsolis RM,Bäumler AJ,Heffron F

更新日期：1995-05-01 00:00:00

abstract：:Trypanosoma musculi produces a chronic infection with a consistently elevated parasitemia in nude mice. Thymic reconstitution of nude mice restores immunity to the infection. ...

journal_title：Infection and immunity

authors： Rank RG,Roberts DW,Weidanz WP

更新日期：1977-05-01 00:00:00

abstract：:Borrelia burgdorferi, the causative agent of Lyme disease, loses its ability to infect and cause disease in mammalian hosts after repeated in vitro passage. To identify proteins preferentially expressed by the low-passage strain and thus representing potential virulence factors, the polypeptide profiles of virulent, l...

journal_title：Infection and immunity

authors： Norris SJ,Carter CJ,Howell JK,Barbour AG

更新日期：1992-11-01 00:00:00

abstract：:Thirty-two clinical isolates of Shiga-like toxin (SLT)-producing Escherichia coli associated with single cases or outbreaks of bloody diarrhea, hemorrhagic colitis, the hemolytic uremic syndrome, or edema disease of swine were examined for multiple copies of genes belonging to the slt-I or slt-II toxin families. Five ...

journal_title：Infection and immunity

authors： Schmitt CK,McKee ML,O'Brien AD

更新日期：1991-03-01 00:00:00

abstract：:Lipid compositions of 40 patient isolates of Mycobacterium tuberculosis derived from Madras, Burma, Rangoon, and East Africa were studied, and two major populations of tubercle bacilli were distinguished. Nearly all of the strains previously designated as attenuated for the guinea pig (D. A. Mitchison) are characteriz...

journal_title：Infection and immunity

authors： Goren MB,Brokl O,Schaefer WB

更新日期：1974-01-01 00:00:00

abstract：:The mucosal humoral immune response elicited following Shigella flexneri infection in patients living in Antananarivo districts (Madagascar Island) was evaluated by measuring the gut-derived, circulating immunoglobulin A (IgA) antibody-secreting cells (ASC) specific for the major bacterial antigen lipopolysaccharide (...

journal_title：Infection and immunity

authors： Rasolofo-Razanamparany V,Cassel-Beraud AM,Roux J,Sansonetti PJ,Phalipon A

更新日期：2001-09-01 00:00:00

abstract：:The recent development of acellular pertussis vaccines has been a significant improvement in the conventional whole-cell diphtheria-pertussis-tetanus toxoid vaccines, but high production costs will limit its widespread use in developing countries. Since Mycobacterium bovis BCG vaccination against tuberculosis is used ...

journal_title：Infection and immunity

authors： Nascimento IP,Dias WO,Mazzantini RP,Miyaji EN,Gamberini M,Quintilio W,Gebara VC,Cardoso DF,Ho PL,Raw I,Winter N,Gicquel B,Rappuoli R,Leite LC

更新日期：2000-09-01 00:00:00

abstract：:Bartonella bacilliformis is the etiologic agent of Oroya fever in humans. Flagellum-mediated motility has been postulated as a major virulence factor for invasion of host cells. To address this hypothesis, we purified and characterized flagella from strain KC584 and then assessed their role in human erythrocyte associ...

journal_title：Infection and immunity

authors： Scherer DC,DeBuron-Connors I,Minnick MF

更新日期：1993-12-01 00:00:00

abstract：:Salmonella infection can cause gastroenteritis in healthy individuals or a serious, systemic infection in immunocompromised patients and has a global impact. CD4 Th1 cells represent the main lymphocyte population that participates in bacterial clearance during both primary and secondary infections in mice of the H-2b ...

journal_title：Infection and immunity

authors： Labuda JC,Depew CE,Pham OH,Benoun JM,Ramirez NA,McSorley SJ

更新日期：2019-10-18 00:00:00

abstract：:Bacillus cereus causes exotoxin-mediated diarrheal food poisoning. Hemolysin BL (HBL) is a well-characterized B. cereus toxin composed of three components (B, L1, and L2) that together possess hemolytic, cytotoxic, dermonecrotic, and vascular permeability activities. Here, we show that HBL causes fluid accumulation in...

journal_title：Infection and immunity

authors： Beecher DJ,Schoeni JL,Wong AC

更新日期：1995-11-01 00:00:00

abstract：:Cholera toxin has been widely used to obtain insight into the cellular dynamics of the antigen-specific mucosal immune response. The present study was undertaken to clarify the influence of the organized intestinal lymphoid tissue (Peyer's patches [PP]) on the distribution of anti-cholera-toxin-containing cells (ACC) ...

journal_title：Infection and immunity

authors： Enders GA,Delius M,Ballhaus S,Brendel W

更新日期：1987-09-01 00:00:00

abstract：:The lymphogranuloma venereum (LGV) and trachoma biovars of Chlamydia trachomatis exhibit differences in biological properties both in vivo and in vitro. To identify analogous biochemical differences, we studied the molecular charges of chlamydial outer membrane proteins (OMPs) by means of isoelectric focusing and none...

journal_title：Infection and immunity

authors： Batteiger BE,Newhall WJ 5th,Jones RB

更新日期：1985-11-01 00:00:00

abstract：:We recently determined that passive transfer of serum directed against a synthetic peptide called LB1 or a recombinant fusion protein immunogen [LPD-LB1(f)(2,1,3)] could prevent otitis media after challenge with a homologous nontypeable Haemophilus influenzae (NTHI) isolate. NTHI residing in the nasopharynx was rapidl...

journal_title：Infection and immunity

authors： Kennedy BJ,Novotny LA,Jurcisek JA,Lobet Y,Bakaletz LO

更新日期：2000-05-01 00:00:00

abstract：:Gonococci from opaque colonies have cell wall outer membrane proteins that are lacking from organisms which form transparent colonies. These "colony opacity-associated" proteins are among a group of "minor" proteins that exhibit heat modification of their apparent subunit molecular sizes, are easily extracted by deoxy...

journal_title：Infection and immunity

authors： Swanson J

更新日期：1980-04-01 00:00:00

abstract：:The goal of this study is to evaluate the contribution of mast cells to Helicobacter pylori immunity in a model of vaccine-induced protection. Mast cell-deficient Kitl(Sl)/Kitl(Sl-d) and control mice were immunized with H. pylori sonicate plus cholera toxin and challenged with H. pylori, and the bacterial loads, infla...

journal_title：Infection and immunity

authors： Ding H,Nedrud JG,Wershil B,Redline RW,Blanchard TG,Czinn SJ

更新日期：2009-12-01 00:00:00

abstract：:The gene encoding a nitric oxide reductase has been identified in Neisseria gonorrhoeae. The norB gene product shares significant identity with the nitric oxide reductases in Ralstonia eutropha and Synechocystis sp. and, like those organisms, the gonococcus lacks a norC homolog. The gonococcal norB gene was found to b...

journal_title：Infection and immunity

authors： Householder TC,Fozo EM,Cardinale JA,Clark VL

更新日期：2000-09-01 00:00:00

abstract：:Bordetella pertussis adenylate cyclase-hemolysin (AC-Hly), encoded by the cyaA gene, belongs to the RTX family of toxins with extensive glycine-rich repeats in the carboxy-terminal portion. AC-Hly possesses both adenylate cyclase toxic and hemolytic activities that depend on a posttranslational modification mediated b...

journal_title：Infection and immunity

authors： Betsou F,Sebo P,Guiso N

更新日期：1993-09-01 00:00:00

abstract：:Recent studies revealed that acetylation is a widely used protein modification in prokaryotic organisms. The major protein acetylation acetyltransferase YfiQ and the sirtuin-like deacetylase CobB have been found to be involved in basic physiological processes, such as primary metabolism, chemotaxis, and stress respons...

journal_title：Infection and immunity

authors： Liu W,Tan Y,Cao S,Zhao H,Fang H,Yang X,Wang T,Zhou Y,Yan Y,Han Y,Song Y,Bi Y,Wang X,Yang R,Du Z

更新日期：2018-05-22 00:00:00

abstract：:Streptococcus suis is one of the most important pathogens affecting the swine industry and is also an emerging zoonotic agent for humans. Two-component signaling systems (TCSs) play important roles in the adaptation of pathogenic bacteria to host environments. In this study, we identified a novel TCS, named TCS09HKRR,...

journal_title：Infection and immunity

authors： Zhong X,Zhang Y,Zhu Y,Dong W,Ma J,Pan Z,Yao H

更新日期：2019-08-21 00:00:00

abstract：:Human gingival fibroblasts were exposed in culture to cell extracts of different black-pigmented Bacteroides species, and their growth was monitored by determining thymidine uptake and counting cells. Of the Bacteroides species tested (B. gingivalis, B. asaccharolyticus, and B. intermedius), B. gingivalis gave the ext...

journal_title：Infection and immunity

authors： Larjava H,Uitto VJ,Eerola E,Haapasalo M

更新日期：1987-01-01 00:00:00

abstract：:Pathogenic members of the Yersinia genus require the translocator protein LcrV for proper function of the type III secretion apparatus, which is crucial for virulence. LcrV has also been reported to play an independent immunosuppressive role via the induction of interleukin-10 (IL-10) through stimulation of Toll-like ...

journal_title：Infection and immunity

authors： Pouliot K,Pan N,Wang S,Lu S,Lien E,Goguen JD

更新日期：2007-07-01 00:00:00

abstract：:Studies conducted with F1 and F2 progeny of crosses between strains of inbred mice that differ greatly in their capacity to make an antibody response to type III pneumococcal polysaccharide, dextran B-1355, and lipopolysaccharide from Escherichia coli 0113 have shown that multiple genes influence the magnitude of the ...

journal_title：Infection and immunity

authors： Baker PJ,Rudbach JA,Prescott B,Caldes G,Evans C,Stashak PW

更新日期：1984-07-01 00:00:00

abstract：:The response of ferrets after intranasal inoculation of inactivated A/Hong Kong/68 (H3N2) influenza virus vaccines is reported. Normal ferrets given either saline vaccine in drops or freeze-dried vaccine in an aerosol intranasally did not produce detectable serum or nasal hemagglutination inhibiting antibody and were ...

journal_title：Infection and immunity

authors： McLaren C,Potter CW,Jennings R

更新日期：1974-06-01 00:00:00

abstract：:Iron is an important element for the growth of microorganisms as well as in the defense of the host by serving as a catalyst for the generation of free radicals via the Fenton/Haber-Weiss reactions. The iron transporter natural resistance-associated macrophage protein 1 (Nramp1) confers resistance to the growth of a v...

journal_title：Infection and immunity

authors： Zhong W,Lafuse WP,Zwilling BS

更新日期：2001-11-01 00:00:00