当前位置： SCI文献检索 > DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY期刊下所有文献 > Molecular cloning of the porcine RANTES promoter: functional characterization of dsDNA/dsRNA response elements in PK-15 cells.

Molecular cloning of the porcine RANTES promoter: functional characterization of dsDNA/dsRNA response elements in PK-15 cells.

Abstract：

:The chemokine RANTES plays an essential role in inflammation and immune response. In this study, we cloned the nucleotide sequence of the 5'-flanking region of the porcine RANTES (poRANTES) gene and characterized the regulatory elements that activate transcription. Analyses of a series of 5' deletion constructs demonstrated that a 266 bp region (-220/+46) that spanned the potential transcription start site of the poRANTES gene was sufficient to activate transcription in PK-15 cells. Furthermore, our results indicated that dsDNA/dsRNA significantly induced poRANTES promoter activity and expression of mRNA levels in a time- and dose-dependent manner. Promoter deletions and mutagenesis experiments indicated that an interferon-stimulated responsive element (ISRE) was critical for dsDNA/dsRNA-induced poRANTES transcription. In addition, porcine interferon regulatory factor 3 (IRF-3) and IRF-7 play important roles in dsDNA/dsRNA-induced poRANTES expression.

journal_name

Dev Comp Immunol

journal_title

Developmental and comparative immunology

authors

Wang D,Fang L,Li P,Chen Q,Luo R,Chen H,Xiao S

doi

10.1016/j.dci.2010.10.008

subject

Has Abstract

pub_date

2011-03-01 00:00:00

pages

345-51

issue

3

eissn

0145-305X

issn

1879-0089

pii

S0145-305X(10)00254-5

journal_volume

35

pub_type

杂志文章

相关文献

DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY文献大全
  • Partial characterization of chicken spleen cell culture supernatants stimulated with Staphylococcus aureus.

    abstract：:The role of accessory cells in the proliferative response of chicken spleen cells to Staphylococcus aureus Cowan I (SAC) was examined. It was found that chicken spleen cells cultured with SAC produced a soluble molecule capable of causing proliferation when culture supernatants were added to spleen cells. The molecule...

    journal_title：Developmental and comparative immunology

    pub_type： 杂志文章

    doi：10.1016/0145-305x(87)90020-6

    authors： Schoof DD,Tempelis CH

    更新日期：1987-01-01 00:00:00

  • Nonspecific cytotoxic cells in fish (Ictalurus punctatus). II. Parameters of target cell lysis and specificity.

    abstract：:Fish nonspecific cytotoxic cells (NCC) lyse various transformed human B-cells (NC-37, P3HR-1) and erythroblastoid cells (K562) as well as mouse YAC-1 and P815 cells. Highest NCC activity was found in the anterior (head) kidney, but spleen cells and peripheral blood leucocytes (PBL) also demonstrated cytolytic abilitie...

    journal_title：Developmental and comparative immunology

    pub_type： 杂志文章

    doi：10.1016/0145-305x(84)90037-5

    authors： Evans DL,Graves SS,Cobb D,Dawe DL

    更新日期：1984-04-01 00:00:00

  • Establishment and characterization of two head kidney macrophage cell lines from large yellow croaker (Larimichthys crocea).

    abstract：:Two continuous macrophage cell lines (LCM07 and LCM10) were established for the first time from the head kidney of the marine fish large yellow croaker (Larimichthys crocea). To date, both cell lines have been subcultured for more than 100 passages in 12 months. Notably, the LCM07 and LCM10 cells have distinct morphol...

    journal_title：Developmental and comparative immunology

    pub_type： 杂志文章

    doi：10.1016/j.dci.2019.103477

    authors： Cui K,Li Q,Xu D,Zhang J,Gao S,Xu W,Mai K,Ai Q

    更新日期：2020-01-01 00:00:00

  • Cloning of the IL-1β3 gene and IL-1β4 pseudogene in salmonids uncovers a second type of IL-1β gene in teleost fish.

    abstract：:To date two closely related interleukin-1β genes (IL-1β1 and IL-β2) have been found in salmonids. The cloning of trout and salmon IL-1β3, and a salmon IL-1β4 pseudogene reveals that two types of IL-1β genes exist in teleost species. Type I teleost IL-1β genes, including salmonid IL-1β3, share a similar 6 coding exon s...

    journal_title：Developmental and comparative immunology

    pub_type： 杂志文章

    doi：10.1016/j.dci.2012.07.010

    authors： Husain M,Bird S,van Zwieten R,Secombes CJ,Wang T

    更新日期：2012-11-01 00:00:00

  • Phylogenetic and expression analysis of lamprey toll-like receptors.

    abstract：:Toll-like receptors (TLRs) have been identified as pivotal sensors recognizing microbial pattern molecules in vertebrates. Whole genome analysis of the teleost Takifugu rubripes supports the existence of a fundamental family of TLR genes in fish. However, the role of the innate immune system in the context of raising ...

    journal_title：Developmental and comparative immunology

    pub_type： 杂志文章

    doi：10.1016/j.dci.2010.03.004

    authors： Kasamatsu J,Oshiumi H,Matsumoto M,Kasahara M,Seya T

    更新日期：2010-08-01 00:00:00

  • Functional characterization of avidins in amphioxus Branchiostoma japonicum: Evidence for a dual role in biotin-binding and immune response.

    abstract：:Avidin is well known for its high affinity to biotin and has been found in many egg-laying vertebrate species. However, little is known about avidin in invertebrate species to date. Here we clearly showed the presence of two avidin genes, Bjavidin1 and Bjavidin2, in the amphioxus Branchiostoma japonicum, the first one...

    journal_title：Developmental and comparative immunology

    pub_type： 杂志文章

    doi：10.1016/j.dci.2017.01.006

    authors： Guo X,Xin J,Wang P,Du X,Ji G,Gao Z,Zhang S

    更新日期：2017-05-01 00:00:00

  • Expression, signal transduction, and function analysis of TIRAP and TRIF in Nile tilapia (Oreochromis niloticus).

    abstract：:Toll/interleukin 1 receptor domain-containing adaptor protein (TIRAP) and toll/interleukin 1 receptor-domain-containing adapter-inducing interferon-β (TRIF) are crucial adaptors of signal transduction for the signaling pathways of toll-like receptors (TLRs). TIRAP and TRIF perform an essential function in an antimicro...

    journal_title：Developmental and comparative immunology

    pub_type： 杂志文章

    doi：10.1016/j.dci.2020.103991

    authors： Trung NB,Nan FH,Wang IJ,Wu YC,Wen CM,Lee MC,Hang HT,Lee PT

    更新日期：2021-04-01 00:00:00

  • Identification and characterization of the first reptilian CD9, and its expression analysis in response to bacterial infection.

    abstract：:In this study, a CD9 homologue in a reptile, Chinese soft-shelled turtle, has been cloned and identified for the first time. The full-length cDNA of turtle CD9 was 1146bp and contained a 672bp open reading frame (ORF) coding for a protein of 224 amino acids. Four transmembrane domains (TMs) divided the turtle CD9 into...

    journal_title：Developmental and comparative immunology

    pub_type： 杂志文章

    doi：10.1016/j.dci.2009.09.001

    authors： Zhou X,Feng H,Guo Q,Dai H

    更新日期：2010-02-01 00:00:00

  • Characterization and signaling pathway analysis of interferon-kappa in bovine.

    abstract：:A bovine interferon-kappa (BoIFN-κ) gene was amplified, which encodes a protein of 215 amino acids sharing 63% identity with human IFN-κ. BoIFN-κ was demonstrated to have antiviral and antiproliferative activities. Moreover, BoIFN-κ was shown to be highly sensitive to trypsin, however, it remained stable despite chang...

    journal_title：Developmental and comparative immunology

    pub_type： 杂志文章

    doi：10.1016/j.dci.2016.09.018

    authors： Guo Y,An D,Liu Y,Bao J,Luo X,Cheng X,Wang Y,Gao M,Wang J

    更新日期：2017-02-01 00:00:00

  • Trypanosoma carassii hsp70 increases expression of inflammatory cytokines and chemokines in macrophages of the goldfish (Carassius auratus L.).

    abstract：:We report on the cloning and characterization of Trypanosoma carassii 70 KDa heat shock protein (hsp70). T. carassii hsp70 was secreted/excreted into culture medium in vitro and was recognized by sera from infected fish. Recombinant hsp70 (rhsp70) activated goldfish macrophages and stimulated the production of pro-inf...

    journal_title：Developmental and comparative immunology

    pub_type： 杂志文章

    doi：10.1016/j.dci.2009.06.003

    authors： Oladiran A,Belosevic M

    更新日期：2009-10-01 00:00:00

  • Duck lymphocytes. IV. Collective effects of mitogens.

    abstract：:Duck (Anas platyrhynchos) blood lymphocytes were cultured in the presence of phytohaemagglutinin (PHA), concanavalin A (Con A), pokeweed mitogen (PWM), lentil lectin (LL), Roman snail lectin (HP), wheat germ agglutinin (WGA), Bandeiraea simplicifolia seed lectin (BSS), peanut agglutinin (PNA), horseshoe crab lectin (H...

    journal_title：Developmental and comparative immunology

    pub_type： 杂志文章

    doi：10.1016/0145-305x(91)90028-w

    authors： Higgins DA

    更新日期：1991-10-01 00:00:00

  • Teleost contributions to the understanding of mycobacterial diseases.

    abstract：:Few pathogens have shaped human medicine as the mycobacteria. From understanding biological phenomena driving disease spread, to mechanisms of host-pathogen interactions and antibiotic resistance, the Mycobacterium genus continues to challenge and offer insights into the basis of health and disease. Teleost fish model...

    journal_title：Developmental and comparative immunology

    pub_type： 杂志文章,评审

    doi：10.1016/j.dci.2019.02.011

    authors： Hodgkinson JW,Belosevic M,Elks PM,Barreda DR

    更新日期：2019-07-01 00:00:00

  • Phenoloxidase and QX disease resistance in Sydney rock oysters (Saccostrea glomerata).

    abstract：:QX is a fatal disease in Sydney rock oysters (Saccostrea glomerata) that results from infection by the protistan parasite, Marteilia sydneyi. Since 1997, the New South Wales Fisheries Service has bred S. glomerata for resistance to QX disease. The current study shows that the QX resistance breeding program has selecte...

    journal_title：Developmental and comparative immunology

    pub_type： 杂志文章

    doi：10.1016/j.dci.2003.10.004

    authors： Newton K,Peters R,Raftos D

    更新日期：2004-05-17 00:00:00

  • Effects of Trichobilharzia ocellata on hemocytes of Lymnaea stagnalis.

    abstract：:We analyzed the effects of infection with Trichobilharzia ocellata on hemocytes of its snail host, Lymnaea stagnalis, and correlated them with successive stages of parasite development. Circulating hemocytes were studied at 0, 2, 4, 6, and 8 weeks post exposure (p.e.) with respect to cell number, distribution of subpo...

    journal_title：Developmental and comparative immunology

    pub_type： 杂志文章

    doi：10.1016/0145-305x(91)90001-f

    authors： Amen RI,Tijnagel JM,van der Knaap WP,Meuleman EA,de Lange-de Klerk ES,Sminia T

    更新日期：1991-04-01 00:00:00

  • Comparative ontogenetic development of two marine teleosts, gilthead seabream and European sea bass: New insights into nutrition and immunity.

    abstract：:Gilthead seabream and European sea bass are two of the most commonly farmed fish species. Larval development is critical to ensure high survival rates and thus avoid unacceptable economic losses, while nutrition and immunity are also important factors. For this reason this paper evaluates the ontogenetic development o...

    journal_title：Developmental and comparative immunology

    pub_type： 杂志文章

    doi：10.1016/j.dci.2016.06.011

    authors： Cordero H,Guzmán-Villanueva LT,Chaves-Pozo E,Arizcun M,Ascencio-Valle F,Cuesta A,Esteban MA

    更新日期：2016-12-01 00:00:00

  • HSP70 gene expression in Mytilus galloprovincialis hemocytes is triggered by moderate heat shock and Vibrio anguillarum, but not by V. splendidus or Micrococcus lysodeikticus.

    abstract：:Complete sequence of HSP70 cDNA from the mussel, Mytilus galloprovincialis was established before quantifying its expression following moderate heat shock or injection of heat-killed bacteria. HSP70 cDNA is comprised of 2378 bp including one ORF of 654 aa, with a predicted 70 bp 5'-UTR and a 343 bp 3'-UTR (GenBank, 18...

    journal_title：Developmental and comparative immunology

    pub_type： 杂志文章

    doi：10.1016/j.dci.2005.12.009

    authors： Cellura C,Toubiana M,Parrinello N,Roch P

    更新日期：2006-01-01 00:00:00

  • The bovine genomic DNA sequence data reveal three IGHV subgroups, only one of which is functionally expressed.

    abstract：:A comprehensive analysis of cattle shotgun sequencing data reveals 36 immunoglobulin heavy chain variable genes. The previously described bovine subgroup IGHV1 contains 10 functional genes with a conserved promoter including the consensus octamer and several other transcription factor binding sites, intact exons and m...

    journal_title：Developmental and comparative immunology

    pub_type： 杂志文章

    doi：10.1016/j.dci.2012.02.006

    authors： Niku M,Liljavirta J,Durkin K,Schroderus E,Iivanainen A

    更新日期：2012-07-01 00:00:00

  • An ancient C-type lectin in Chlamys farreri (CfLec-2) that mediate pathogen recognition and cellular adhesion.

    abstract：:C-type lectins are a superfamily of Ca(2+) dependent carbohydrate-recognition proteins which play significant diverse roles in nonself-recognition and clearance of invaders. In the present study, a C-type lectin (CfLec-2) from Zhikong scallop Chlamys farreri was selected to investigate its functions in innate immunity...

    journal_title：Developmental and comparative immunology

    pub_type： 杂志文章

    doi：10.1016/j.dci.2010.07.004

    authors： Yang J,Qiu L,Wei X,Wang L,Wang L,Zhou Z,Zhang H,Liu L,Song L

    更新日期：2010-12-01 00:00:00

  • Immunogenetics of disease resistance in fish: a comparative approach.

    abstract：:The study of the genetic regulation of infectious disease resistance depends on the availability of inbred lines or selection lines of the species under investigation. The small numbers of such lines of fish has limited the strategy in teleosts to studies of associations between disease and immune/health traits. Attem...

    journal_title：Developmental and comparative immunology

    pub_type： 杂志文章,评审

    doi：10.1016/s0145-305x(96)00032-8

    authors： Wiegertjes GF,Stet RJ,Parmentier HK,van Muiswinkel WB

    更新日期：1996-11-01 00:00:00

  • Molecular cloning and characterisation of the griffon vulture (Gyps fulvus) toll-like receptor 1.

    abstract：:The toll-like receptor (TLR) family is an ancient pattern recognition receptor family, conserved from insects to mammals. Members of the TLR family are vital to immune function through the sensing of pathogenic agents and initiation of an appropriate immune response. In this study, we cloned a cDNA encoding for a grif...

    journal_title：Developmental and comparative immunology

    pub_type： 杂志文章

    doi：10.1016/j.dci.2006.08.003

    authors： de la Lastra JM,de la Fuente J

    更新日期：2007-01-01 00:00:00

  • Atlantic salmon IPS-1 mediates induction of IFNa1 and activation of NF-kappaB and localizes to mitochondria.

    abstract：:The striking difference in evolution of type I IFN genes of fish and mammals poses the question of whether these genes are induced through similar or different signalling pathways in the two vertebrate groups. Previous work has shown that expression of both Atlantic salmon (Salmo salar) IFNa1 and mammalian IFN-beta ge...

    journal_title：Developmental and comparative immunology

    pub_type： 杂志文章

    doi：10.1016/j.dci.2009.06.012

    authors： Lauksund S,Svingerud T,Bergan V,Robertsen B

    更新日期：2009-11-01 00:00:00

  • The production of toxic oxygen metabolites by hemocytes of different snail species.

    abstract：:The phagocytic hemocytes of four snail species were investigated for their ability to generate reactive oxygen metabolites upon stimulation by foreign material. Hemocytes of the pond snail Lymnaea stagnalis and of the garden snail Helix aspersa showed a luminol-dependent chemiluminescence (CL) when they phagocytosed z...

    journal_title：Developmental and comparative immunology

    pub_type： 杂志文章

    doi：10.1016/0145-305x(88)90068-7

    authors： Dikkeboom R,van der Knaap WP,van den Bovenkamp W,Tijnagel JM,Bayne CJ

    更新日期：1988-07-01 00:00:00

  • Identification of a target cell antigen recognized by nonspecific cytotoxic cells using an anti-idiotype monoclonal antibody.

    abstract：:Nonspecific cytotoxic cells (NCC) are the teleost equivalent of mammalian natural killer (NK) cells. In the present study an anti-idiotypic monoclonal antibody (mAb 7D12) was generated against idiotopes on an mAb (mAb 6D3.2) that recognizes a putative receptor on NCC. The idiotypic specificity of mAb 7D12 was determin...

    journal_title：Developmental and comparative immunology

    pub_type： 杂志文章

    doi：10.1016/0145-305x(94)90014-0

    authors： Lester JP 3rd,Evans DL,Leary JH 3rd,Fowler SC,Jaso-Friedmann L

    更新日期：1994-05-01 00:00:00

  • Ontogeny and thymus-dependence of T cell surface antigens in Xenopus: flow cytometric studies on monoclonal antibody-stained thymus and spleen.

    abstract：:Recently generated anti-Xenopus T cell monoclonal antibodies (mAbs) to the 120 kDa XTLA-1 determinant and against the putative CD5 and CD8 homologues, together with anti-IgM and anti-MHC class II mAbs, are used in dual colour flow cytometric experiments to characterize cell surface antigenic expression on lymphocytes ...

    journal_title：Developmental and comparative immunology

    pub_type： 杂志文章

    doi：10.1016/0145-305x(95)00030-w

    authors： Gravenor I,Horton TL,Ritchie P,Flint E,Horton JD

    更新日期：1995-11-01 00:00:00

  • Diversity of the immunoglobulin heavy chain in the Atlantic salmon (Salmo salar L.) is contributed by genes from two parallel IgH isoloci.

    abstract：:Immunoglobulin heavy chain (IgH) variable (V) region cDNAs from the Atlantic salmon, Salmo salar L., have been isolated and analysed with respect to diversity and transcription of the two parallel IgH isoloci in this species. A total of nine V(H) families were defined according to the 80% identity criterion, of which ...

    journal_title：Developmental and comparative immunology

    pub_type： 杂志文章

    doi：10.1016/s0145-305x(01)00008-8

    authors： Solem ST,Hordvik I,Killie JA,Warr GW,Jørgensen TO

    更新日期：2001-06-01 00:00:00

  • In vivo and in vitro knockdown of FREP2 gene expression in the snail Biomphalaria glabrata using RNA interference.

    abstract：:RNA interference (RNAi) is reported here for the first time for Biomphalaria glabrata, the snail intermediate host for the human parasite Schistosoma mansoni. The fibrinogen-related protein 2 (FREP2) gene, normally expressed at increased levels following exposure to digenetic trematode parasites, such as S. mansoni or...

    journal_title：Developmental and comparative immunology

    pub_type： 杂志文章

    doi：10.1016/j.dci.2005.12.004

    authors： Jiang Y,Loker ES,Zhang SM

    更新日期：2006-01-01 00:00:00

  • Using models of nucleotide evolution to build phylogenetic trees.

    abstract：:Molecular phylogenetics and its applications are popular and useful tools for making comparative investigations in genetics; however, estimating phylogenetic trees is not always straightforward. Some phylogenetic estimators use an explicit model of nucleotide evolution to estimate evolutionary parameters such as branc...

    journal_title：Developmental and comparative immunology

    pub_type： 杂志文章,评审

    doi：10.1016/j.dci.2004.07.007

    authors： Bos DH,Posada D

    更新日期：2005-01-01 00:00:00

  • Molecular characterization and function of a PTEN gene from Litopenaeus vannamei after Vibrio alginolyticus challenge.

    abstract：:PTEN, a tumor suppressor gene, suppresses cell survival, growth, apoptosis, cell migration and DNA damage repair by inhibiting the PI3K/AKT signaling pathway. In this study, the full-length Litopenaeus vannamei PTEN (LvPTEN) cDNA was obtained, containing a 5'UTR of 59bp, an ORF of 1269bp and a 3'UTR of 146bp besides t...

    journal_title：Developmental and comparative immunology

    pub_type： 杂志文章

    doi：10.1016/j.dci.2016.01.004

    authors： Xie CY,Kong JR,Zhao CS,Xiao YC,Peng T,Liu Y,Wang WN

    更新日期：2016-06-01 00:00:00

  • Fish immune responses to parasitic copepod (namely sea lice) infection.

    abstract：:Parasitic copepods, in particular sea lice, have considerable impacts upon global freshwater and marine fisheries, with major economic consequences recognized primarily in aquaculture. Sea lice have been a contentious issue with regards to interactions between farmed and wild populations of fish, in particular salmoni...

    journal_title：Developmental and comparative immunology

    pub_type： 杂志文章,评审

    doi：10.1016/j.dci.2013.08.019

    authors： Fast MD

    更新日期：2014-04-01 00:00:00

  • A comparison of phenoloxidase activity in the blood of marine invertebrates.

    abstract：:A range of marine invertebrates were screened for prophenoloxidase (a marker protein of the prophenoloxidase activating system) in the coelomic fluid or hemolymph. The crustaceans and the ascidian, Ciona intestinalis, displayed strongest activity, with low levels found in the starfish, Asterias rubens, the sea urchin,...

    journal_title：Developmental and comparative immunology

    pub_type： 杂志文章

    doi：10.1016/0145-305x(91)90018-t

    authors： Smith VJ,Söderhäll K

    更新日期：1991-10-01 00:00:00