Phenoloxidase and QX disease resistance in Sydney rock oysters (Saccostrea glomerata).

abstract：:Kazal-type serine proteinase inhibitors (KPIs) function in physiological and immunological processes requiring proteinase action. In the present study, the first Cherax quadricarinatus KPI gene (designated CqKPI) was identified and characterized. The open reading frame of CqKPI contains 405 nucleotides and encodes a p...

journal_title：Developmental and comparative immunology

authors： Wang Y,Wang B,Liu M,Jiang K,Wang M,Wang L

更新日期：2021-01-01 00:00:00

abstract：:The phagocytic hemocytes of four snail species were investigated for their ability to generate reactive oxygen metabolites upon stimulation by foreign material. Hemocytes of the pond snail Lymnaea stagnalis and of the garden snail Helix aspersa showed a luminol-dependent chemiluminescence (CL) when they phagocytosed z...

journal_title：Developmental and comparative immunology

authors： Dikkeboom R,van der Knaap WP,van den Bovenkamp W,Tijnagel JM,Bayne CJ

更新日期：1988-07-01 00:00:00

abstract：:The αβ T cells are important components of the adaptive immune system and can recognize a vast array of peptides presented by MHC molecules. The ability of these T cells to recognize the complex depends on the diversity of the αβ TR, which is generated by a recombination of specific Variable, Diversity and Joining gen...

journal_title：Developmental and comparative immunology

authors： Antonacci R,Bellini M,Pala A,Mineccia M,Hassanane MS,Ciccarese S,Massari S

更新日期：2017-11-01 00:00:00

abstract：:Five large multigene families encoding innate-type immune receptors that are comprised of immunoglobulin domains have been identified in bony fish, of which four do not possess definable mammalian orthologs. The members of some of the multigene families exhibit unusually extensive patterns of divergence and the indivi...

journal_title：Developmental and comparative immunology

authors： Rodríguez-Nunez I,Wcisel DJ,Litman GW,Yoder JA

更新日期：2014-09-01 00:00:00

abstract：:The intestinal immune system in Gallus species must rapidly adapt to the omnivorous onset of an adult diet and to colonization by commensal bacteria. Yet, acquired immune functions in Gallus digestive tract fully develop only towards the end of the first week post-hatch. This raises the question of immune protection i...

journal_title：Developmental and comparative immunology

authors： Bar-Shira E,Friedman A

更新日期：2006-01-01 00:00:00

abstract：:Phagocytosis provides a critical first line of defense against invading pathogens. Engagement of particles through receptor-mediated binding precedes internalization and induction of cellular antimicrobial responses. Phagocytes have the capacity to differentially regulate binding and internalization processes through ...

journal_title：Developmental and comparative immunology

authors： Rieger AM,Hall BE,Barreda DR

更新日期：2010-11-01 00:00:00

abstract：:C-type lectins can act as pattern recognition receptors (PRRs) in innate immunity. Previously, we identified two C-type lectins from silkworm (Bombyx mori), BmLBP and BmMBP, as PRRs. In the present study, we identified three homologs of these lectins by searching the silkworm genome database. These novel B. mori low-e...

journal_title：Developmental and comparative immunology

authors： Takase H,Watanabe A,Yoshizawa Y,Kitami M,Sato R

更新日期：2009-06-01 00:00:00

abstract：:A five-domain Kazal-type serine proteinase inhibitor, SPIPm2, from Penaeus monodon has recently been implicated in antiviral responses for it is up-regulated upon viral infection and needs further studies. The SPIPm2 genomic gene was composed of seven exons and six introns. The genomic DNA segments coding for each Kaz...

journal_title：Developmental and comparative immunology

authors： Donpudsa S,Ponprateep S,Prapavorarat A,Visetnan S,Tassanakajon A,Rimphanitchayakit V

更新日期：2010-10-01 00:00:00

abstract：:Recently, we have reported the structural determination of antimicrobial peptides (AMPs), such as riptocin, rip-defensin, and rip-thanatin, from Riptortus pedestris. However, the biological roles of AMPs in the host midgut remain elusive. Here, we compared the expression levels of AMP genes in apo-symbiotic insects wi...

journal_title：Developmental and comparative immunology

authors： Park KE,Jang SH,Lee J,Lee SA,Kikuchi Y,Seo YS,Lee BL

更新日期：2018-01-01 00:00:00

abstract：:Horses greater than 20 years of age exhibit alterations in their immune responses similar to those observed in other aged individuals. The purpose of this study was to characterize immunosenescence in a population of aged ponies. The peripheral blood mononuclear cells (PBMC) from aged ponies exhibited a decreased prol...

journal_title：Developmental and comparative immunology

authors： Horohov DW,Kydd JH,Hannant D

更新日期：2002-01-01 00:00:00

abstract：:Tick defensins are antimicrobial peptides that play a major role in the innate immunity of ticks by providing a direct antimicrobial defense. In this study, we identified and characterized a defensin-like encoding gene, HEdefensin, from the expressed sequence tags (EST) database of hemolymph from the hard tick Haemaph...

journal_title：Developmental and comparative immunology

authors： Talactac MR,Yada Y,Yoshii K,Hernandez EP,Kusakisako K,Maeda H,Galay RL,Fujisaki K,Mochizuki M,Tanaka T

更新日期：2017-03-01 00:00:00

abstract：:IκBα is a member of the NF-κB inhibitor family that inhibits NF-κB activity by sequestering NF-κB in an inactive form in the cytosol. Unlike mammalian IκBα, which has been extensively studied, very little is known about the function of fish IκBα. In this study, we identified and analyzed an IκBα homologue, CsIκBα from...

journal_title：Developmental and comparative immunology

authors： Zhang M,Xiao ZZ,Sun L

更新日期：2012-01-01 00:00:00

abstract：:Forkhead-box O (FoxO) is the primary transcriptional effector of the insulin-like signaling pathway that enhances gluconeogenesis through transcriptional activation of PEPCK and G6Pase in mammals. We have previously demonstrated the involvement of phosphoenolpyruvate carboxykinase (BmPEPCK-2) in antiviral immunity aga...

journal_title：Developmental and comparative immunology

authors： Kang X,Wang Y,Liang W,Tang X,Zhang Y,Wang L,Zhao P,Lu Z

更新日期：2021-03-01 00:00:00

abstract：:At birth the tissues of marsupial immune system are underdeveloped. The young animal is not immunocompetent. Histological and immunohistochemical studies of pouch young epithelial tissues provide a clear picture of tissue development but the timing of onset of immunocompetence awaits definition. The survival of the ne...

journal_title：Developmental and comparative immunology

authors： Old JM,Deane EM

更新日期：2000-07-01 00:00:00

abstract：:During Anuran metamorphosis larval structures regress, adult structures form anew and impaired T cell immune functions are noted, as are alterations in endogenous glucocorticoid titers. In situ histological data, after staining for DNA fragmentation, reveal patterns of lymphocyte suicide in the thymus and spleen of no...

journal_title：Developmental and comparative immunology

authors： Grant P,Clothier RH,Johnson RO,Ruben LN

更新日期：1998-07-01 00:00:00

abstract：:Previous studies demonstrated that porcine plasma ficolin binds the important pig pathogen Actinobacillus pleuropneumoniae (APP) in an N-acetylglucosamine-dependent manner. In the present study, attempts to characterize the bacterial-binding properties of ficolin indicated ficolin is the major porcine plasma protein t...

journal_title：Developmental and comparative immunology

authors： Brooks AS,DeLay JP,Hayes MA

更新日期：2003-10-01 00:00:00

abstract：:Serine protease inhibitors (SPIs) play a key role in physiological responses by controlling protease activities. In this study, we studied the biochemical functions of serpin-15, an SPI, from Bombyx mori (Bmserpin-15). Recombinant Bmserpin-15 was expressed in Escherichia coli cells and used to raise rabbit anti-Bmserp...

journal_title：Developmental and comparative immunology

authors： Liu D,Wang L,Yang L,Qian C,Wei G,Dai L,Li J,Zhu B,Liu C

更新日期：2015-07-01 00:00:00

abstract：:We describe a novel antigen recognized by mAb 2E3 selectively expressed in the periphery by a subset of porcine CD4+ T cells. Both, CD4+CD8alpha- and CD4+CD8alphalow T cell subpopulations express this antigen. CD4+2E3+ T cells show phenotypical and functional characteristics of nai;ve cells. The majority of them are C...

journal_title：Developmental and comparative immunology

authors： Revilla C,Rodríguez-Carreño MP,Alvarez B,Chamorro S,Alonso LM,Ezquerra A,Alonso F,Domínguez J

更新日期：2004-03-01 00:00:00

abstract：:This study compared hemocyte responses of eastern and Pacific oysters to Perkinsus marinus, in vitro. Except for the percentage of hemocytes associated with P. marinus there was little or no significant difference between eastern and Pacific oysters with regard to their hemocytic response to P. marinus. In phagocytosi...

journal_title：Developmental and comparative immunology

authors： La Peyre JF,Chu FL,Vogelbein WK

更新日期：1995-07-01 00:00:00

abstract：:Neonates of all species, including foals, are highly susceptible to infection, and neutrophils play a crucial role in innate immunity to infection. Evidence exists that neutrophils of neonatal foals are functionally deficient during the first weeks of life, including expression of cytokine genes such as IFNG. We hypot...

journal_title：Developmental and comparative immunology

authors： Dindot SV,Doan RN,Kuskie KR,Hillman PR,Whitfield CM,McQueen CM,Bordin AI,Bourquin JR,Cohen ND

更新日期：2018-10-01 00:00:00

abstract：:Marek's disease (MD) vaccines, although effective in reducing lymphoproliferation, cannot control infectious virus production in the feather follicle epithelium (FFE) which is the site of virus shedding. Therefore, we investigated Marek's disease virus (MDV) replication as well as the expression of cytokine genes in f...

journal_title：Developmental and comparative immunology

authors： Abdul-Careem MF,Read LR,Parvizi P,Thanthrige-Don N,Sharif S

更新日期：2009-04-01 00:00:00

abstract：:An in vitro method for organ culture of embryonic bursa of Fabricius is presented. It is shown that bursa cells proliferate in in vitro culture as evidenced by [3H]-thymidine incorporation. We assessed the expression of B-cell alloantigen (Bu-la and Bu-lb), class I (B-F) and class II (B-L) antigens of chicken major hi...

journal_title：Developmental and comparative immunology

authors： Nowak JS,Vainio O,Lassila O

更新日期：1990-04-01 00:00:00

abstract：:TLR7 subfamily members are important pattern recognition receptors participating in the recognition of pathogen-associated molecular patterns. In this study, we successfully identified 3 members of TLR7 subfamily from the spiny eel Mastacembelus armatus (MaTLR7, MaTLR8 and MaTLR9). The amino acid sequence identities o...

journal_title：Developmental and comparative immunology

authors： Han C,Li Q,Liu J,Hao Z,Huang J,Zhang Y

更新日期：2019-06-01 00:00:00

abstract：:CD8, belonging to the TCR complex, is the main marker molecule of CTLs. Although CD8 genes have been detected in many fish species, the analysis of teleost CD8+ cells has been limited because of the lack of antibodies. Using newly established mAbs against rainbow trout CD8α, we found high ratios of CD8α+ cells in trou...

journal_title：Developmental and comparative immunology

authors： Takizawa F,Dijkstra JM,Kotterba P,Korytář T,Kock H,Köllner B,Jaureguiberry B,Nakanishi T,Fischer U

更新日期：2011-07-01 00:00:00

abstract：:Cytotoxic morula cells (MCs) and phagocytes are the circulating immunocytes of the colonial ascidian Botryllus schlosseri: Both these cells can synthesise amyloid fibrils, supporting the idea that physiological amyloidogenesis is involved in inflammation and modulation of immune responses. Intriguingly, amyloid of B. ...

journal_title：Developmental and comparative immunology

authors： Franchi N,Ballarin L,Peronato A,Cima F,Grimaldi A,Girardello R,de Eguileor M

更新日期：2019-01-01 00:00:00

abstract：:Photorhabdus bacteria enter into a mutualistic symbiosis with Heterorhabditis nematodes to infect insect larvae. However, they rapidly kill the model nematode Caenorhabditis elegans. One hypothesis for these divergent outcomes is that the nematode defense responses differ. To begin testing this hypothesis, we have sys...

journal_title：Developmental and comparative immunology

authors： Hoinville ME,Wollenberg AC

更新日期：2018-05-01 00:00:00

abstract：:Erythropoietin receptor (EPOR) is a member of the class I cytokine receptor superfamily and signaling through this receptor is important for the proliferation, differentiation and survival of erythrocyte progenitor cells. This study reports on the molecular and functional characterization of goldfish EPOR. The identif...

journal_title：Developmental and comparative immunology

authors： Katakura F,Katzenback BA,Belosevic M

更新日期：2014-08-01 00:00:00

abstract：:Two continuous macrophage cell lines (LCM07 and LCM10) were established for the first time from the head kidney of the marine fish large yellow croaker (Larimichthys crocea). To date, both cell lines have been subcultured for more than 100 passages in 12 months. Notably, the LCM07 and LCM10 cells have distinct morphol...

journal_title：Developmental and comparative immunology

authors： Cui K,Li Q,Xu D,Zhang J,Gao S,Xu W,Mai K,Ai Q

更新日期：2020-01-01 00:00:00

abstract：:Cellular and humoral aspects of the immune response develop sequentially in the fetus. During the ontogeny, the pluripotent stem cells emerge and differentiate into all hematopoietic lineages. Basic questions including the identification of the first lympho-hematopoietic sites, the origin of T and B lymphocytes, the d...

journal_title：Developmental and comparative immunology

authors： Sinkora M,Butler JE

更新日期：2009-03-01 00:00:00

abstract：:Though Bombyx mori larvae possess five types of hemocytes in the hemolymph, the granular cells play a key role as phagocytes and also participate in the early phase of encapsulation together with plasmacytes. In this sense, these two hemocytes are regarded as immunocompetent cells in B.mori. A granular cell can intern...

journal_title：Developmental and comparative immunology

authors： Wago H

更新日期：1982-10-01 00:00:00