当前位置： SCI文献检索 > DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY期刊下所有文献 > Ontogeny and thymus-dependence of T cell surface antigens in Xenopus: flow cytometric studies on monoclonal antibody-stained thymus and spleen.

Ontogeny and thymus-dependence of T cell surface antigens in Xenopus: flow cytometric studies on monoclonal antibody-stained thymus and spleen.

Abstract：

:Recently generated anti-Xenopus T cell monoclonal antibodies (mAbs) to the 120 kDa XTLA-1 determinant and against the putative CD5 and CD8 homologues, together with anti-IgM and anti-MHC class II mAbs, are used in dual colour flow cytometric experiments to characterize cell surface antigenic expression on lymphocytes in thymus and spleen of Xenopus laevis during larval and early adult life and also in metamorphosis-inhibited animals. Histological confirmation of T cell emergence early in larval ontogeny is supplied by cryostat sections stained for CD8. Five-day thymectomy, i.e. prior to T-lineage cell differentiation in the thymus, abolishes T cell marker expression in the spleen for up to 1 year. Moreover, late larval (20 days) or early adult (3 months) thymectomy (i.e. removal after peripheralization of T cells has occurred) also leads to severe depletion of mAb-defined T cells in the spleen.

journal_name

Dev Comp Immunol

journal_title

Developmental and comparative immunology

authors

Gravenor I,Horton TL,Ritchie P,Flint E,Horton JD

doi

10.1016/0145-305x(95)00030-w

subject

Has Abstract

pub_date

1995-11-01 00:00:00

pages

507-23

issue

6

eissn

0145-305X

issn

1879-0089

pii

0145305X9500030W

journal_volume

19

pub_type

杂志文章

相关文献

DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY文献大全
  • Cloning and functional characterization of rat stimulator of interferon genes (STING) regulated by miR-24.

    abstract：:Stimulator of interferon (IFN) genes (STING), also known as MPYS/MITA/ERIS/TMEM173, is a recently discovered adaptor protein that functions downstream of RIG-I and upstream of TBK1 and plays an important role in type I interferon (IFN) production. Mammalian STINGs have been isolated from human, mouse, pig, cattle and ...

    journal_title：Developmental and comparative immunology

    pub_type： 杂志文章

    doi：10.1016/j.dci.2012.02.010

    authors： Huang Z,Chen X,Yu B,Chen D

    更新日期：2012-07-01 00:00:00

  • The upregulation of immune responses in tyrosine hydroxylase (TH) silenced Litopenaeus vannamei.

    abstract：:Catecholamines (CAs) play a crucial role in maintaining physiological and immune homeostasis in invertebrates and vertebrates under stressful conditions. Tyrosine hydroxylase (TH) is the first and rate-limiting enzyme in CA synthesis. To develop an effective CA-related immunological defense system against stress and p...

    journal_title：Developmental and comparative immunology

    pub_type： 杂志文章

    doi：10.1016/j.dci.2016.11.002

    authors： Mapanao R,Chang CC,Cheng W

    更新日期：2017-02-01 00:00:00

  • microRNA-589-5p modulates the expression of hemocyanin as part of the anti-WSSV immune response in Litopenaeus vannamei.

    abstract：:The respiratory glycoprotein, hemocyanin (HMC) has multiple immune-related functions, including antiviral activity. In this study, in silico methods were used to predict seven miRNAs targeting Litopenaeus vannamei HMC (LvHMC), out of which miR-589-5p was selected for further investigation because of its role in immune...

    journal_title：Developmental and comparative immunology

    pub_type： 杂志文章

    doi：10.1016/j.dci.2020.103642

    authors： Bao S,Zheng Z,Aweya JJ,Yao D,Li S,Sun C,Hong Y,Zhang Y

    更新日期：2020-06-01 00:00:00

  • Isolation and characterization of a human alternative complement pathway-inhibiting protein from larval hemolymph of the silkworm, Bombyx mori.

    abstract：:An alternative complement pathway-inhibiting protein (ACPIP), which inhibits the activation of the alternative complement pathway (ACP) of the human serum, was isolated from larval hemolymph of the silkworm, Bombyx mori, by using ammonium sulfate fractionation and column chromatographies to homogeneity. About 400micro...

    journal_title：Developmental and comparative immunology

    pub_type： 杂志文章

    doi：10.1016/s0145-305x(00)00046-x

    authors： Sekijima Y,Fujikura Y,Hiyama T,Maenaka T,Uda A

    更新日期：2001-03-01 00:00:00

  • Anopheles gambiae hemocytes exhibit transient states of activation.

    abstract：:Hemocytes are crucial players of the mosquito immune system and critically affect transmission of pathogens including malaria parasites. We and others discovered previously that a blood meal is a major immune stimulus for mosquito hemocytes. To determine whether these blood meal-induced hemocyte changes in Anopheles g...

    journal_title：Developmental and comparative immunology

    pub_type： 杂志文章

    doi：10.1016/j.dci.2015.10.020

    authors： Bryant WB,Michel K

    更新日期：2016-02-01 00:00:00

  • PcLys-i3, an invertebrate lysozyme, is involved in the antibacterial immunity of the red swamp crayfish, Procambarus clarkii.

    abstract：:Antimicrobial peptides (AMPs) play important roles in innate immunity against pathogens and lysozymes are a particularly type of AMP. Lysozymes are hydrolytic enzymes that are characterized by their ability to cleave the beta-(1,4)-glycosidic bond between N-acetylmuramic acid and N-acetylglucosamine in peptidoglycan, ...

    journal_title：Developmental and comparative immunology

    pub_type： 杂志文章

    doi：10.1016/j.dci.2018.05.020

    authors： Liu Y,Zhang YH,Li T,Cao XT,Zhou Y,Yuan JF,Gu ZM,Lan JF

    更新日期：2018-10-01 00:00:00

  • Identification and functional characterization of Dicer2 and five single VWC domain proteins of Litopenaeus vannamei.

    abstract：:Dicer (Dcr) is the key protein of the RNA interference (RNAi) pathway. To investigate the role of the RNAi pathway in shrimp anti-viral immunity, Litopenaeus vannamei Dcr2 (designated as LvDcr2) was identified and characterized. The full-length cDNA of LvDcr2 was 5513bp long, with an open reading frame encoding a puta...

    journal_title：Developmental and comparative immunology

    pub_type： 杂志文章

    doi：10.1016/j.dci.2011.01.010

    authors： Chen YH,Jia XT,Zhao L,Li CZ,Zhang S,Chen YG,Weng SP,He JG

    更新日期：2011-06-01 00:00:00

  • The oyster immunity.

    abstract：:Oysters, the common name for a number of different bivalve molluscs, are the worldwide aquaculture species and also play vital roles in the function of ecosystem. As invertebrate, oysters have evolved an integrated, highly complex innate immune system to recognize and eliminate various invaders via an array of orchest...

    journal_title：Developmental and comparative immunology

    pub_type： 杂志文章,评审

    doi：10.1016/j.dci.2017.05.025

    authors： Wang L,Song X,Song L

    更新日期：2018-03-01 00:00:00

  • A novel IgA-like immunoglobulin in the reptile Eublepharis macularius.

    abstract：:The appearance of antibody genes over evolution coincided with the origin of the vertebrates. Reptiles are of great interest in evolution since they are the link between the amphibians, birds, and mammals. This work describes the presence of a gene in the reptile leopard gecko (Eublepharis macularius) where phylogenet...

    journal_title：Developmental and comparative immunology

    pub_type： 杂志文章

    doi：10.1016/j.dci.2006.09.005

    authors： Deza FG,Espinel CS,Beneitez JV

    更新日期：2007-01-01 00:00:00

  • Identification and characterization of a novel phage-type like lysozyme from Manila clam, Ruditapes philippinarum.

    abstract：:A novel lysozyme gene (RpLysPh) with high similarity to the bacteriophage lysozymes was identified in Manila clam, Ruditapes philippinarum. The full length cDNA of RpLysPh is 828bp and contains a 462bp open reading frame (ORF) that codes for a 154 amino acid protein. Multiple sequence alignment analysis revealed that ...

    journal_title：Developmental and comparative immunology

    pub_type： 杂志文章

    doi：10.1016/j.dci.2014.06.013

    authors： Ding J,Wang R,Yang F,Zhao L,Qin Y,Zhang G,Yan X

    更新日期：2014-11-01 00:00:00

  • Exploring the relationships between amphibian (Xenopus laevis) myeloid cell subsets.

    abstract：:The differentiation of distinct leukocyte subsets is governed by lineage-specific growth factors that elicit disparate expression of transcription factors and markers by the developing cell populations. For example, macrophages (Mφs) and granulocytes (Grns) arise from common granulocyte-macrophage progenitors in respo...

    journal_title：Developmental and comparative immunology

    pub_type： 杂志文章

    doi：10.1016/j.dci.2020.103798

    authors： Yaparla A,Koubourli DV,Popovic M,Grayfer L

    更新日期：2020-12-01 00:00:00

  • Cloning and characterising an unusual perforin from chicken (Gallus gallus).

    abstract：:In mammals the 67 kDa pore-forming protein perforin is essential to the granule exocytosis pathway used by cytotoxic lymphocytes to eliminate virally infected and malignant cells. There is indirect evidence that this pathway exists in lower vertebrates such as teleost fish and birds, although in genome databases for t...

    journal_title：Developmental and comparative immunology

    pub_type： 杂志文章

    doi：10.1016/j.dci.2013.05.003

    authors： D'Angelo ME,Arjomand A,Trapani JA,Bird PI

    更新日期：2013-10-01 00:00:00

  • Analysis of 52 Rab GTPases from channel catfish and their involvement in immune responses after bacterial infections.

    abstract：:Rab genes, encoding a large family of monomeric G-proteins, contain over 60 members in the human genome. They have been recognized as crucial regulators for membrane trafficking including cargo sorting, vesicle formation, budding, motility, docking, fusion, secretory and endocytic pathway of host immune responses. How...

    journal_title：Developmental and comparative immunology

    pub_type： 杂志文章

    doi：10.1016/j.dci.2014.01.026

    authors： Wang R,Zhang Y,Liu S,Li C,Sun L,Bao L,Feng J,Liu Z

    更新日期：2014-07-01 00:00:00

  • cDNA cloning, expression and bioactivity of porcine BAFF.

    abstract：:B cell activating factor belonging to the tumor necrosis factor (TNF) family (BAFF) is critical for B cell survival, maturation and T cell activation by acting through its three receptors, BAFF-R, BCMA and TACI. In the present study, a porcine BAFF cDNA, designated pBAFF, was cloned by RT-PCR and rapid amplification o...

    journal_title：Developmental and comparative immunology

    pub_type： 杂志文章

    doi：10.1016/j.dci.2007.03.006

    authors： Guan ZB,Dan WB,Shui Y,Ye JL,Zhang SQ

    更新日期：2007-01-01 00:00:00

  • Hemolin-A lepidopteran anti-viral defense factor?

    abstract：:Immunity in insects has largely focused on responses towards bacteria and fungi, but recently the study of immune responses against viral infections has also received attention. In Lepidoptera, phagocytosis and encapsulation mediated by hemocytes, and apoptosis are part of the response against virus infection; however...

    journal_title：Developmental and comparative immunology

    pub_type： 杂志文章,评审

    doi：10.1016/j.dci.2007.09.006

    authors： Terenius O

    更新日期：2008-01-01 00:00:00

  • Molecular cloning, characterization and function of a germinal center kinase MST4 gene from Litopenaeus vannamei in response to Vibrio alginolyticus challenge in TLR-TRAF6 signaling pathway.

    abstract：:The serine/threonine protein kinase MST4 plays multiple roles in the regulation of signaling pathways that govern cellular processes including mitosis, migration, homeostasis, polarity, proliferation, differentiation and apoptosis. Here we report the identification and characterization of the full-length sequence of L...

    journal_title：Developmental and comparative immunology

    pub_type： 杂志文章

    doi：10.1016/j.dci.2017.03.026

    authors： Zhao CS,Huang D,Peng T,Huang MZ,Xie CY,Chen J,Kong JR,Xie RC,Liu Y,Wang WN

    更新日期：2017-08-01 00:00:00

  • Phenoloxidase and QX disease resistance in Sydney rock oysters (Saccostrea glomerata).

    abstract：:QX is a fatal disease in Sydney rock oysters (Saccostrea glomerata) that results from infection by the protistan parasite, Marteilia sydneyi. Since 1997, the New South Wales Fisheries Service has bred S. glomerata for resistance to QX disease. The current study shows that the QX resistance breeding program has selecte...

    journal_title：Developmental and comparative immunology

    pub_type： 杂志文章

    doi：10.1016/j.dci.2003.10.004

    authors： Newton K,Peters R,Raftos D

    更新日期：2004-05-17 00:00:00

  • A longitudinal study of the protein components of marsupial milk from birth to weaning in the tammar wallaby (Macropus eugenii).

    abstract：:The major milk whey proteins of the tammar wallaby (Macropus eugenii) have been identified over the total period of lactation using proteomic analysis techniques comprising two-dimensional electrophoresis, comparative image analysis, matrix assisted laser desorption ionisation mass spectrometry (MALDI MS), de novo pep...

    journal_title：Developmental and comparative immunology

    pub_type： 杂志文章

    doi：10.1016/j.dci.2008.08.002

    authors： Joss JL,Molloy MP,Hinds L,Deane E

    更新日期：2009-02-01 00:00:00

  • Lipopolysaccharide activates the sea urchin immune system.

    abstract：:Profilin is a small, actin-binding protein that functions at the intersection of signal transduction and cytoskeletal modifications. Increases in the number of profilin messages per cell correlate with sea urchin coelomocytes activation in response to injury. Here we show that coelomocytes respond to immune challenge ...

    journal_title：Developmental and comparative immunology

    pub_type： 杂志文章

    doi：10.1016/0145-305x(95)00009-i

    authors： Smith LC,Britten RJ,Davidson EH

    更新日期：1995-05-01 00:00:00

  • A comparison of phenoloxidase activity in the blood of marine invertebrates.

    abstract：:A range of marine invertebrates were screened for prophenoloxidase (a marker protein of the prophenoloxidase activating system) in the coelomic fluid or hemolymph. The crustaceans and the ascidian, Ciona intestinalis, displayed strongest activity, with low levels found in the starfish, Asterias rubens, the sea urchin,...

    journal_title：Developmental and comparative immunology

    pub_type： 杂志文章

    doi：10.1016/0145-305x(91)90018-t

    authors： Smith VJ,Söderhäll K

    更新日期：1991-10-01 00:00:00

  • Development of the immune system and immunological protection in marsupial pouch young.

    abstract：:At birth the tissues of marsupial immune system are underdeveloped. The young animal is not immunocompetent. Histological and immunohistochemical studies of pouch young epithelial tissues provide a clear picture of tissue development but the timing of onset of immunocompetence awaits definition. The survival of the ne...

    journal_title：Developmental and comparative immunology

    pub_type： 杂志文章,评审

    doi：10.1016/s0145-305x(00)00008-2

    authors： Old JM,Deane EM

    更新日期：2000-07-01 00:00:00

  • EcVig, a novel grouper immune-gene associated with antiviral activity against NNV infection.

    abstract：:VHSV-induced genes (VIGs) were first identified in rainbow trout (Oncorhynchus mykiss) and subsequently isolated in a variety of fish. Recent studies have shown that most VIGs have immunological functions against pathogenic infections. However, most research has focused on Vig1, such that our present understanding of ...

    journal_title：Developmental and comparative immunology

    pub_type： 杂志文章

    doi：10.1016/j.dci.2013.10.014

    authors： Yeh YC,Hsu YJ,Chen YM,Lin HY,Yang HL,Chen TY,Wang HC

    更新日期：2014-03-01 00:00:00

  • Phenylalanine hydroxylase from the sponge Geodia cydonium: implication for allorecognition and evolution of aromatic amino acid hydroxylases.

    abstract：:The prophenoloxidase activating system is a defense system, frequently reported both in protostomes and in deuterostomes. The final product of the phenoloxidase activity is melanin which is ubiquitously present throughout the metazoan kingdom. The melanin synthesis pathway starts with the amino acid [aa] phenylalanine...

    journal_title：Developmental and comparative immunology

    pub_type： 杂志文章

    doi：10.1016/s0145-305x(98)00034-2

    authors： Wiens M,Koziol C,Batel R,Müller WE

    更新日期：1998-09-01 00:00:00

  • Molecular cloning and characterization of autophagy-related gene TmATG8 in Listeria-invaded hemocytes of Tenebrio molitor.

    abstract：:Macroautophagy (hereinafter called autophagy) is a highly regulated process used by eukaryotic cells to digest portions of the cytoplasm that remodels and recycles nutrients and disposes of unwanted cytoplasmic constituents. Currently 36 autophagy-related genes (ATG) and their homologs have been characterized in yeast...

    journal_title：Developmental and comparative immunology

    pub_type： 杂志文章

    doi：10.1016/j.dci.2015.02.017

    authors： Tindwa H,Jo YH,Patnaik BB,Lee YS,Kang SS,Han YS

    更新日期：2015-07-01 00:00:00

  • Atlantic salmon IPS-1 mediates induction of IFNa1 and activation of NF-kappaB and localizes to mitochondria.

    abstract：:The striking difference in evolution of type I IFN genes of fish and mammals poses the question of whether these genes are induced through similar or different signalling pathways in the two vertebrate groups. Previous work has shown that expression of both Atlantic salmon (Salmo salar) IFNa1 and mammalian IFN-beta ge...

    journal_title：Developmental and comparative immunology

    pub_type： 杂志文章

    doi：10.1016/j.dci.2009.06.012

    authors： Lauksund S,Svingerud T,Bergan V,Robertsen B

    更新日期：2009-11-01 00:00:00

  • Uncovering the evolutionary history of innate immunity: the simple metazoan Hydra uses epithelial cells for host defence.

    abstract：:Although many properties of the innate immune system are shared among multicellular animals, the evolutionary origin remains poorly understood. Here we characterize the innate immune system in Hydra, one of the simplest multicellular animals known. In the complete absence of both protective mechanical barriers and mob...

    journal_title：Developmental and comparative immunology

    pub_type： 杂志文章

    doi：10.1016/j.dci.2008.10.004

    authors： Bosch TC,Augustin R,Anton-Erxleben F,Fraune S,Hemmrich G,Zill H,Rosenstiel P,Jacobs G,Schreiber S,Leippe M,Stanisak M,Grötzinger J,Jung S,Podschun R,Bartels J,Harder J,Schröder JM

    更新日期：2009-04-01 00:00:00

  • Localization of anti-lipopolysaccharide factor (ALFPm3) in tissues of the black tiger shrimp, Penaeus monodon, and characterization of its binding properties.

    abstract：:Anti-lipopolysaccharide factor (ALF) is an antimicrobial peptide originally identified from horseshoe crabs and recently found in several shrimp species. ALFPm3, the most abundant isoform in the black tiger shrimp, Penaeus monodon, has been shown to possess a broad spectrum of antimicrobial activity against Gram-negat...

    journal_title：Developmental and comparative immunology

    pub_type： 杂志文章

    doi：10.1016/j.dci.2008.03.008

    authors： Somboonwiwat K,Bachère E,Rimphanitchayakit V,Tassanakajon A

    更新日期：2008-01-01 00:00:00

  • Lymphocyte markers in the bovine foetus.

    abstract：:The ontogeny of lymphocyte surface markers was studied in thymus, retropharyngeal lymph nodes, spleen, bone marrow, and liver of 48 bovine foetuses, 80-280 days of gestation. The markers examined were the spontaneous (E) rosette against sheep erythrocytes (SRBCs) in foetal calf serum (E/FCS), in medium supplemented wi...

    journal_title：Developmental and comparative immunology

    pub_type： 杂志文章

    doi：10.1016/0145-305x(83)90018-6

    authors： Higgins DA,Stack MJ,Richardson C

    更新日期：1983-04-01 00:00:00

  • Identification of a second immunoglobulin in the most primitive shark, the frill shark, Chlamydoselachus anguineus.

    abstract：:Three molecular forms of immunoglobulins: pentamer, dimer and monomer, were isolated from serum of the frill shark, Chlamydoselachus anguineus, the most primitive extant shark. A pentamer having an apparent mass of 900 kDa, consisting of 68 kDa heavy (H) chains and 22-24 kDa light (L) chains, was considered to be IgM ...

    journal_title：Developmental and comparative immunology

    pub_type： 杂志文章

    doi：10.1016/0145-305x(92)90004-v

    authors： Kobayashi K,Tomonaga S,Tanaka S

    更新日期：1992-07-01 00:00:00

  • Crustins: enigmatic WAP domain-containing antibacterial proteins from crustaceans.

    abstract：:Crustins are antibacterial proteins of ca. 7-14 kDa with a characteristic four-disulphide core-containing whey acidic protein (WAP) domain, expressed by the circulating haemocytes of crustaceans. Over 50 crustin sequences have been now reported from a variety of decapods, including crabs, lobsters, shrimp and crayfish...

    journal_title：Developmental and comparative immunology

    pub_type： 杂志文章,评审

    doi：10.1016/j.dci.2007.12.002

    authors： Smith VJ,Fernandes JM,Kemp GD,Hauton C

    更新日期：2008-01-01 00:00:00