当前位置： SCI文献检索 > DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY期刊下所有文献 > Uncovering the evolutionary history of innate immunity: the simple metazoan Hydra uses epithelial cells for host defence.

Uncovering the evolutionary history of innate immunity: the simple metazoan Hydra uses epithelial cells for host defence.

Abstract：

:Although many properties of the innate immune system are shared among multicellular animals, the evolutionary origin remains poorly understood. Here we characterize the innate immune system in Hydra, one of the simplest multicellular animals known. In the complete absence of both protective mechanical barriers and mobile phagocytes, Hydra's epithelium is remarkably well equipped with potent antimicrobial peptides to prevent pathogen infection. Induction of antimicrobial peptide production is mediated by the interaction of a leucine-rich repeats (LRRs) domain containing protein with a TIR-domain containing protein lacking LRRs. Conventional Toll-like receptors (TLRs) are absent in the Hydra genome. Our findings support the hypothesis that the epithelium represents the ancient system of host defence.

journal_name

Dev Comp Immunol

journal_title

Developmental and comparative immunology

authors

Bosch TC,Augustin R,Anton-Erxleben F,Fraune S,Hemmrich G,Zill H,Rosenstiel P,Jacobs G,Schreiber S,Leippe M,Stanisak M,Grötzinger J,Jung S,Podschun R,Bartels J,Harder J,Schröder JM

doi

10.1016/j.dci.2008.10.004

subject

Has Abstract

pub_date

2009-04-01 00:00:00

pages

559-69

issue

4

eissn

0145-305X

issn

1879-0089

pii

S0145-305X(08)00232-2

journal_volume

33

pub_type

杂志文章

相关文献

DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY文献大全
  • Interferon-gamma induces differentiation of ectoplacental cone cells to phenotypically distinct trophoblasts.

    abstract：:Maturation of the murine ectoplacental cone results in the development of the placental tissue which essentially consists of two trophoblastic zones, the spongiotrophoblast and labyrinthine trophoblast. In this study we attempted to investigate the action of cytokines on ectoplacental cone cell differentiation to matu...

    journal_title：Developmental and comparative immunology

    pub_type： 杂志文章

    doi：10.1016/s0145-305x(00)00023-9

    authors： Athanassakis I,Papadimitriou L,Bouris G,Vassiliadis S

    更新日期：2000-09-01 00:00:00

  • Heat shock 70 kDa protein cognate 5 involved in WSSV toleration of Litopenaeus vannamei.

    abstract：:The expression levels of 97 unigenes encoding heat shock proteins of Litopenaeus vannamei was scanned, and ten of them were significantly induced by white spot syndrome virus (WSSV). Among these genes, heat shock 70 kDa protein cognate 5 (LvHSC70-5) was upregulated to the highest extent and subjected to further studie...

    journal_title：Developmental and comparative immunology

    pub_type： 杂志文章

    doi：10.1016/j.dci.2017.02.003

    authors： Yuan K,Yuan FH,He HH,Bi HT,Weng SP,He JG,Chen YH

    更新日期：2017-07-01 00:00:00

  • Immunogenetics of disease resistance in fish: a comparative approach.

    abstract：:The study of the genetic regulation of infectious disease resistance depends on the availability of inbred lines or selection lines of the species under investigation. The small numbers of such lines of fish has limited the strategy in teleosts to studies of associations between disease and immune/health traits. Attem...

    journal_title：Developmental and comparative immunology

    pub_type： 杂志文章,评审

    doi：10.1016/s0145-305x(96)00032-8

    authors： Wiegertjes GF,Stet RJ,Parmentier HK,van Muiswinkel WB

    更新日期：1996-11-01 00:00:00

  • Purification and binding properties of porcine plasma ficolin that binds Actinobacillus pleuropneumoniae.

    abstract：:Previous studies demonstrated that porcine plasma ficolin binds the important pig pathogen Actinobacillus pleuropneumoniae (APP) in an N-acetylglucosamine-dependent manner. In the present study, attempts to characterize the bacterial-binding properties of ficolin indicated ficolin is the major porcine plasma protein t...

    journal_title：Developmental and comparative immunology

    pub_type： 杂志文章

    doi：10.1016/s0145-305x(03)00057-0

    authors： Brooks AS,DeLay JP,Hayes MA

    更新日期：2003-10-01 00:00:00

  • In silico analysis of Schmidtea mediterranea TIR domain-containing proteins.

    abstract：:While genetic evidence points towards an absence of Toll-Like Receptors (TLRs) in Platyhelminthes, the Toll/IL-1 Receptor (TIR)-domains that drive the assembly of signalling complexes downstream TLR are present in these organisms. Here, we undertook the characterisation of the repertoire of TIR-domain containing prote...

    journal_title：Developmental and comparative immunology

    pub_type： 杂志文章

    doi：10.1016/j.dci.2018.05.004

    authors： Tsoumtsa LL,Sougoufara S,Torre C,Lemichez E,Pontarotti P,Ghigo E

    更新日期：2018-09-01 00:00:00

  • Serum amyloid A transcription in Atlantic salmon (Salmo salar L.) hepatocytes is enhanced by stimulation with macrophage factors, recombinant human IL-1 beta, IL-6 and TNF alpha or bacterial lipopolysaccharide.

    abstract：:Serum amyloid A (A-SAA) has previously been reported to be an acute-phase protein in salmonids. Hepatocytes represent a major source of A-SAA in salmonids, but nothing is known about hepatocyte SAA synthesis in fish. In the present work, the expression of A-SAA transcripts in primary cultures of Atlantic salmon hepato...

    journal_title：Developmental and comparative immunology

    pub_type： 杂志文章

    doi：10.1016/s0145-305x(00)00022-7

    authors： Jørgensen JB,Lunde H,Jensen L,Whitehead AS,Robertsen B

    更新日期：2000-09-01 00:00:00

  • Development of the immune system and immunological protection in marsupial pouch young.

    abstract：:At birth the tissues of marsupial immune system are underdeveloped. The young animal is not immunocompetent. Histological and immunohistochemical studies of pouch young epithelial tissues provide a clear picture of tissue development but the timing of onset of immunocompetence awaits definition. The survival of the ne...

    journal_title：Developmental and comparative immunology

    pub_type： 杂志文章,评审

    doi：10.1016/s0145-305x(00)00008-2

    authors： Old JM,Deane EM

    更新日期：2000-07-01 00:00:00

  • Cellular recognition of foreign materials by Bombyx mori phagocytes: I. Immunocompetent cells.

    abstract：:Though Bombyx mori larvae possess five types of hemocytes in the hemolymph, the granular cells play a key role as phagocytes and also participate in the early phase of encapsulation together with plasmacytes. In this sense, these two hemocytes are regarded as immunocompetent cells in B.mori. A granular cell can intern...

    journal_title：Developmental and comparative immunology

    pub_type： 杂志文章,评审

    doi：

    authors： Wago H

    更新日期：1982-10-01 00:00:00

  • Tissue-specific reduction in DC-SIGN expression correlates with progression of pathogenic simian immunodeficiency virus infection.

    abstract：:Studies were undertaken to determine whether previously described reductions in splenic DC-SIGN expression in simian acquired immune deficiency syndrome (AIDS) are limited to pathogenic simian immunodeficiency virus (SIV) infection. DC-SIGN expression was evaluated by immunohistochemistry in lymphoid tissues from AIDS...

    journal_title：Developmental and comparative immunology

    pub_type： 杂志文章

    doi：10.1016/j.dci.2008.06.006

    authors： Yearley JH,Kanagy S,Anderson DC,Dalecki K,Pauley DR,Suwyn C,Donahoe RM,McClure HM,O'Neil SP

    更新日期：2008-01-01 00:00:00

  • SIKE of black carp is a substrate of TBK1 and suppresses TBK1-mediated antiviral signaling.

    abstract：:RIG-I like receptor (RLR) signaling functions importantly in host innate immune response against RNA virus, which is tightly regulated by a number of mechanisms to prevent aberrant interferon production. The suppressor of IKKε (SIKE) has been identified as a suppressor of IKKε and TBK1, which are key components of RLR...

    journal_title：Developmental and comparative immunology

    pub_type： 杂志文章

    doi：10.1016/j.dci.2018.09.016

    authors： Li J,Yan C,Liu J,Yan J,Feng H

    更新日期：2019-01-01 00:00:00

  • Do ectothermic vertebrates have a home in which to affinity mature their antibody responses?

    abstract：:There has been a longstanding question of whether affinity maturation occurs in ectotherms, and if it does, where in tissues this happens. Although cold-blooded vertebrates (ectotherms) lack histologically discernible germinal centers, they have a fully functional Ig gene mutator enzyme (activation-induced cytidine de...

    journal_title：Developmental and comparative immunology

    pub_type： 杂志文章,评审

    doi：10.1016/j.dci.2021.104021

    authors： Muthupandian A,Waly D,Magor BG

    更新日期：2021-01-19 00:00:00

  • GATA3 mRNA in ginbuna crucian carp (Carassius auratus langsdorfii): cDNA cloning, splice variants and expression analysis.

    abstract：:GATA3, a transcriptional activator, plays a critical role in the development of T-cells and differentiation to T helper type 2 cells. To date, no information is available on the role of GATA3 in the teleost immune system. We identified full-length cDNA and alternatively spliced variants of ginbuna crucian carp GATA3 (...

    journal_title：Developmental and comparative immunology

    pub_type： 杂志文章

    doi：10.1016/j.dci.2008.01.004

    authors： Takizawa F,Mizunaga Y,Araki K,Moritomo T,Ototake M,Nakanishi T

    更新日期：2008-01-01 00:00:00

  • The compatibility of Xenopus antibody and homoiothermic complement.

    abstract：:Adult Xenopus laevis serum containing an anti-chicken erythrocyte antibody exhibits complement (C) activity by both the classical and the alternative pathways. Lytic activity is removed by heating serum to 50 degrees C for at least 20 min; it is also removed by polysaccharides and by 7.5 mM EDTA. The optimum temperatu...

    journal_title：Developmental and comparative immunology

    pub_type： 杂志文章

    doi：10.1016/0145-305x(87)90047-4

    authors： McKnight BJ,Jurd RD

    更新日期：1987-07-01 00:00:00

  • Hemolin-A lepidopteran anti-viral defense factor?

    abstract：:Immunity in insects has largely focused on responses towards bacteria and fungi, but recently the study of immune responses against viral infections has also received attention. In Lepidoptera, phagocytosis and encapsulation mediated by hemocytes, and apoptosis are part of the response against virus infection; however...

    journal_title：Developmental and comparative immunology

    pub_type： 杂志文章,评审

    doi：10.1016/j.dci.2007.09.006

    authors： Terenius O

    更新日期：2008-01-01 00:00:00

  • Functional characterization of STATa/b genes encoding transcription factors from Branchiostoma belcheri.

    abstract：:The signal transducer and activator of transcription (STAT), as an important transcription factor of the Janus kinase (JAK)-STAT signaling pathway, is pivotal for development and immunity and well documented in vertebrates. However, the STAT gene has not been reported in chordate amphioxus (Branchiostoma belcheri). In...

    journal_title：Developmental and comparative immunology

    pub_type： 杂志文章

    doi：10.1016/j.dci.2020.103838

    authors： Cao Y,Fang T,Fan M,Wang L,Lv C,Xiaojun Song,Jin P,Ma F

    更新日期：2021-01-01 00:00:00

  • An ancient and variable mannose-binding lectin from the coral Acropora millepora binds both pathogens and symbionts.

    abstract：:Corals form the framework of the world's coral reefs and are under threat from increases in disease and bleaching (symbiotic dysfunction), yet the mechanisms of pathogen and symbiont recognition remain largely unknown. Here we describe the isolation and characterisation of an ancient mannose-binding lectin in the cora...

    journal_title：Developmental and comparative immunology

    pub_type： 杂志文章

    doi：10.1016/j.dci.2008.05.010

    authors： Kvennefors EC,Leggat W,Hoegh-Guldberg O,Degnan BM,Barnes AC

    更新日期：2008-01-01 00:00:00

  • A bifunctional invertebrate-type lysozyme from the disk abalone, Haliotis discus discus: genome organization, transcriptional profiling and biological activities of recombinant protein.

    abstract：:Lysozyme is an important enzyme in the innate immune system that plays a vital role in fighting microbial infections. In the current study, we identified, cloned, and characterized a gene that encodes an invertebrate-type lysozyme from the disk abalone, Haliotis discus discus (abLysI). The full-length cDNA of abLysI c...

    journal_title：Developmental and comparative immunology

    pub_type： 杂志文章

    doi：10.1016/j.dci.2013.06.009

    authors： Bathige SD,Umasuthan N,Kasthuri SR,Whang I,Lim BS,Nam BH,Lee J

    更新日期：2013-10-01 00:00:00

  • The roles of antimicrobial peptide, rip-thanatin, in the midgut of Riptortus pedestris.

    abstract：:Recently, we have reported the structural determination of antimicrobial peptides (AMPs), such as riptocin, rip-defensin, and rip-thanatin, from Riptortus pedestris. However, the biological roles of AMPs in the host midgut remain elusive. Here, we compared the expression levels of AMP genes in apo-symbiotic insects wi...

    journal_title：Developmental and comparative immunology

    pub_type： 杂志文章

    doi：10.1016/j.dci.2017.09.009

    authors： Park KE,Jang SH,Lee J,Lee SA,Kikuchi Y,Seo YS,Lee BL

    更新日期：2018-01-01 00:00:00

  • Identification and characterization of chicken interleukin-16 cDNA.

    abstract：:Interleukin-16 is an inflammatory cytokine synthesized as a precursor protein (pro-IL-16). Based on sequence data from an EST cDNA library prepared from intestinal intraepithelial lymphocytes of Eimeria-infected chickens, we identified a cDNA that contained a full-length open reading frame of pro-IL-16. The encoded pr...

    journal_title：Developmental and comparative immunology

    pub_type： 杂志文章

    doi：10.1016/s0145-305x(03)00133-2

    authors： Min W,Lillehoj HS

    更新日期：2004-02-01 00:00:00

  • Lipopolysaccharide- and β-1,3-glucan-binding protein from Litopenaeus vannamei: Purification, cloning and contribution in shrimp defense immunity via phenoloxidase activation.

    abstract：:Lipopolysaccharide- and β-1,3-glucan-binding protein (LGBP) existed in diversity of invertebrates including shrimp plays a crucial role in an innate immunity via mediating the recognition of invading pathogens. In this study, LGBP was cloned and characterized from the hepatopancreas of Litopenaeus vannamei, named as L...

    journal_title：Developmental and comparative immunology

    pub_type： 杂志文章

    doi：10.1016/j.dci.2017.11.016

    authors： Phupet B,Pitakpornpreecha T,Baowubon N,Runsaeng P,Utarabhand P

    更新日期：2018-04-01 00:00:00

  • Functions of Bombyx mori cathepsin L-like in innate immune response and anti-microbial autophagy.

    abstract：:Cathepsins belongs to the cysteine protease family, which are activated by an acidic environment. They play essential biological roles in the innate immunity and development of animals. Here, we identified a 62 kDa cathepsin L-like protease from the silkworm Bombyx mori. It contained putative conserved domains, includ...

    journal_title：Developmental and comparative immunology

    pub_type： 杂志文章

    doi：10.1016/j.dci.2020.103927

    authors： Sun YX,Chen C,Xu WJ,Abbas MN,Mu FF,Ding WJ,Zhang HJ,Li J

    更新日期：2021-03-01 00:00:00

  • A comparison of phenoloxidase activity in the blood of marine invertebrates.

    abstract：:A range of marine invertebrates were screened for prophenoloxidase (a marker protein of the prophenoloxidase activating system) in the coelomic fluid or hemolymph. The crustaceans and the ascidian, Ciona intestinalis, displayed strongest activity, with low levels found in the starfish, Asterias rubens, the sea urchin,...

    journal_title：Developmental and comparative immunology

    pub_type： 杂志文章

    doi：10.1016/0145-305x(91)90018-t

    authors： Smith VJ,Söderhäll K

    更新日期：1991-10-01 00:00:00

  • A DM9-containing protein from oyster Crassostrea gigas (CgDM9CP-3) mediating immune recognition and encapsulation.

    abstract：:DM9 domain containing protein (DM9CP) is a recently identified pattern recognition molecules exiting in most organisms except plants. In the present study, a novel DM9-containing protein (CgDM9CP-3) was identified from Pacific oyster Crassostrea gigas with an open reading frame of 438 bp, encoding a polypeptide of 145...

    journal_title：Developmental and comparative immunology

    pub_type： 杂志文章

    doi：10.1016/j.dci.2020.103937

    authors： Liu Y,Wang W,Zhao Q,Yuan P,Li J,Song X,Liu Z,Ding D,Wang L,Song L

    更新日期：2021-03-01 00:00:00

  • Relationship between circulating thyroid hormones and humoral immunity in immature male chickens.

    abstract：:The objective of this experiment was to examine the relationship between levels of circulating T3, T4, and humoral immunity in immature male chickens. Three week old Single Comb White Leghorn male chicks were used as the experimental animals. In order to produce a wide range of circulating thyroid hormone concentratio...

    journal_title：Developmental and comparative immunology

    pub_type： 杂志文章

    doi：10.1016/0145-305x(86)90029-7

    authors： Bachman SE,Mashaly MM

    更新日期：1986-07-01 00:00:00

  • Expression and functional characterization of interferon regulatory factors (irf2, irf7 and irf9) in the blunt snout bream (Megalobrama amblycephala).

    abstract：:Interferon regulatory factors (irfs) are a family of genes that encode transcription factors with important roles in regulating the expression of Type I interferons (IFNs) and other genes associated with related pathways. irfs have multitudinous functions in growth, development and regulation of oncogenesis. In this s...

    journal_title：Developmental and comparative immunology

    pub_type： 杂志文章

    doi：10.1016/j.dci.2016.09.014

    authors： Zhan FB,Liu H,Lai RF,Jakovlić I,Wang WM

    更新日期：2017-02-01 00:00:00

  • Tissue-specific expression and molecular modeling of cytosolic manganese superoxide dismutases from the white shrimp Litopenaeus vannamei.

    abstract：:Manganese superoxide dismutases (MnSODs) are usually mitochondrial enzymes, although there are few examples of cytosolic MnSODs (cMnSOD). We have previously characterized a cMnSOD cDNA from Litopenaeus vannamei hemocytes, and to obtain new insights into the tissue specific expression and the protein structure, we char...

    journal_title：Developmental and comparative immunology

    pub_type： 杂志文章

    doi：10.1016/j.dci.2006.11.007

    authors： Gómez-Anduro GA,Sotelo-Mundo RR,Muhlia-Almazán A,Yepiz-Plascencia G

    更新日期：2007-01-01 00:00:00

  • Developmental regulation of chicken surfactant protein A and its localization in lung.

    abstract：:Surfactant Protein A (SP-A) is a collagenous C-type lectin (collectin) that plays an important role in the early stage of the host immune response. In chicken, SP-A (cSP-A) is expressed as a 26 kDa glycosylated protein in the lung. Using immunohistochemistry, cSP-A protein was detected mainly in the lung lining fluid ...

    journal_title：Developmental and comparative immunology

    pub_type： 杂志文章

    doi：10.1016/j.dci.2016.03.010

    authors： Zhang W,Cuperus T,van Dijk A,Skjødt K,Hansen S,Haagsman HP,Veldhuizen EJ

    更新日期：2016-08-01 00:00:00

  • Molecular characterization and expression analysis of the interleukin 1b gene in Pacific cod (Gadus macrocephalus).

    abstract：:Interleukin 1b (IL-1b) is a member of the cytokine family that serves as major mediators for early pro-inflammatory responses. During artificial breeding of Pacific cod (Gadus macrocephalus), outbreaks of NNV in the early development stages could lead to high mortality. Recent research reported that IL-1b participated...

    journal_title：Developmental and comparative immunology

    pub_type： 杂志文章

    doi：10.1016/j.dci.2018.07.025

    authors： Hu B,Chen B,Mao M,Chen M,Liu X,Cui Q,Liu Y,Jiang C

    更新日期：2018-11-01 00:00:00

  • Humoral immunity factors in cynomolgus macaques (Macaca fascicularis) serum: immunoglobulins and total light chains in nursing dams.

    abstract：:This study was aimed at the identification of variations in humoral immunity parameters during the lactation period in macaque females, a recognized model in reproductive physiology and pathology. The importance of such evaluation is evidenced in particular by the central role played by the maternally transferred immu...

    journal_title：Developmental and comparative immunology

    pub_type： 杂志文章

    doi：10.1016/0145-305x(96)00006-7

    authors： D'Ovidio MC,Pace M,Via F,Iale E,Turillazzi PG,Strom R

    更新日期：1996-03-01 00:00:00

  • Shark class II invariant chain reveals ancient conserved relationships with cathepsins and MHC class II.

    abstract：:The invariant chain (Ii) is the critical third chain required for the MHC class II heterodimer to be properly guided through the cell, loaded with peptide, and expressed on the surface of antigen presenting cells. Here, we report the isolation of the nurse shark Ii gene, and the comparative analysis of Ii splice varia...

    journal_title：Developmental and comparative immunology

    pub_type： 杂志文章

    doi：10.1016/j.dci.2011.09.008

    authors： Criscitiello MF,Ohta Y,Graham MD,Eubanks JO,Chen PL,Flajnik MF

    更新日期：2012-03-01 00:00:00