Lipopolysaccharide activates the sea urchin immune system.

abstract：:Type I interferon (IFN) induces the antiviral response in innate immunity. The type I IFN gene cloned from Japanese flounder (Paralichthys olivaceus) has a length of 1189 bp and consisting of 5 exons and 4 introns. In a phylogenetic tree of type I IFNs, Japanese flounder grouped with other Acanthopterygii. To gain ins...

journal_title：Developmental and comparative immunology

authors： Ohtani M,Hikima J,Hwang SD,Morita T,Suzuki Y,Kato G,Kondo H,Hirono I,Jung TS,Aoki T

更新日期：2012-04-01 00:00:00

abstract：:Single hematopoietic cells from carp (Cyprinus carpio) kidney were seeded to each well of 96-well plates and cultured in the presence of a supporting cell layer and conditioned media (CM). The CM were obtained from bulk-cultured carp hematopoietic cells, in which T and macrophage-lineage cells rapidly proliferated as ...

journal_title：Developmental and comparative immunology

authors： Katakura F,Yamaguchi T,Yoshida M,Moritomo T,Nakanishi T

更新日期：2010-06-01 00:00:00

abstract：:We have purified five types of lectins, named tachylectins, from circulating hemocytes and hemolymph plasma of the Japanese horseshoe crab, Tachypleus tridentatus. Tachylectin-1 interacts with Gram-negative bacteria probably through 2-keto-3-deoxyoctonate, one of the constituents of lipopolysaccharides (LPS). Tachylec...

journal_title：Developmental and comparative immunology

authors： Kawabata S,Iwanaga S

更新日期：1999-06-01 00:00:00

abstract：:In recent years zebrafish has emerged as an excellent model for studying the Cxcl8 signaling pathway in inflammation elicited upon tissue damage or infection. Zebrafish has two true homologs of mammalian CXCL8, named Cxcl8-l1 and Cxcl8-l2. Previously, we have shown that in wound-associated inflammation, these chemokin...

journal_title：Developmental and comparative immunology

authors： de Oliveira S,Lopez-Muñoz A,Martínez-Navarro FJ,Galindo-Villegas J,Mulero V,Calado Â

更新日期：2015-03-01 00:00:00

abstract：:Spleen and thymus suspensions from the turtle, Chelydra serpentina were examined by indirect immunofluorescence and found to contain both agranulocytes and granulocytes positive for surface Ig. Among the splenic agranulocytes , 50% of the lymphocyte and monocyte population was positive for surface Ig. In the thymus on...

journal_title：Developmental and comparative immunology

authors： Mead KF,Borysenko M

更新日期：1984-01-01 00:00:00

abstract：:Transforming growth factor-β activated kinase 1 (TAK1) is a crucial signal transducer in multiple signaling pathways. TAK1 binds TAB1, TAB2, and TAB3, which act as activators and adaptors that specifically regulate the activation of TAK1. To date, the role of TABs is largely unknown in fish. In the present study, a TA...

journal_title：Developmental and comparative immunology

authors： Hu YZ,Li X,Han R,Jiang B,Li YW,Dan XM,Li AX

更新日期：2019-01-01 00:00:00

abstract：:Scanning microdensitometric analysis of Feulgen stained thymocytes from rats aged 1 to 71 days revealed the presence of a number of waves of cell proliferation which may correlate with the development of functionally distinct T-cell subpopulations. In addition, considerable numbers of hypodiploid cells were seen. It i...

journal_title：Developmental and comparative immunology

authors： Rippin JW

更新日期：1984-01-01 00:00:00

abstract：:The presence of phenoloxidase (PO) activity was detected in different developmental stages of the Pacific oyster, Crassostrea gigas. A significant reduction in PO activity was observed from the 6h embryo stage to the day 11 larvae by spectrophotometry. A progressive increase was also observed from the day 13 larvae ri...

journal_title：Developmental and comparative immunology

authors： Thomas-Guyon H,Gagnaire B,Bado-Nilles A,Bouilly K,Lapègue S,Renault T

更新日期：2009-05-01 00:00:00

abstract：:Dynamics of leucocyte infiltration and bacterial invasion in the caecal wall were studied after oral infection of 2-day-old chicks with Salmonella enterica ser. Enteritidis. Bacteria invaded the lamina propria of the caecal wall from 12h post-challenge onwards. Bacteriological examination of internal organs (liver, sp...

journal_title：Developmental and comparative immunology

authors： Van Immerseel F,De Buck J,De Smet I,Mast J,Haesebrouck F,Ducatelle R

更新日期：2002-05-01 00:00:00

abstract：:Innate immune factors play a crucial role in survival of young fish especially during early stages of life when adaptive immunity is not fully developed. In the present study, we investigated the immune response of rainbow trout (Oncorhynchus mykiss) larvae and fry at an early stage of development. We exposed 17 and 8...

journal_title：Developmental and comparative immunology

authors： Chettri JK,Raida MK,Kania PW,Buchmann K

更新日期：2012-02-01 00:00:00

abstract：:The signal transducer and activator of transcription (STAT), as an important transcription factor of the Janus kinase (JAK)-STAT signaling pathway, is pivotal for development and immunity and well documented in vertebrates. However, the STAT gene has not been reported in chordate amphioxus (Branchiostoma belcheri). In...

journal_title：Developmental and comparative immunology

authors： Cao Y,Fang T,Fan M,Wang L,Lv C,Xiaojun Song,Jin P,Ma F

更新日期：2021-01-01 00:00:00

abstract：:CD8, belonging to the TCR complex, is the main marker molecule of CTLs. Although CD8 genes have been detected in many fish species, the analysis of teleost CD8+ cells has been limited because of the lack of antibodies. Using newly established mAbs against rainbow trout CD8α, we found high ratios of CD8α+ cells in trou...

journal_title：Developmental and comparative immunology

authors： Takizawa F,Dijkstra JM,Kotterba P,Korytář T,Kock H,Köllner B,Jaureguiberry B,Nakanishi T,Fischer U

更新日期：2011-07-01 00:00:00

abstract：:The ontogeny of lymphocyte surface markers was studied in thymus, retropharyngeal lymph nodes, spleen, bone marrow, and liver of 48 bovine foetuses, 80-280 days of gestation. The markers examined were the spontaneous (E) rosette against sheep erythrocytes (SRBCs) in foetal calf serum (E/FCS), in medium supplemented wi...

journal_title：Developmental and comparative immunology

authors： Higgins DA,Stack MJ,Richardson C

更新日期：1983-04-01 00:00:00

abstract：:RIG-I like receptor (RLR) signaling functions importantly in host innate immune response against RNA virus, which is tightly regulated by a number of mechanisms to prevent aberrant interferon production. The suppressor of IKKε (SIKE) has been identified as a suppressor of IKKε and TBK1, which are key components of RLR...

journal_title：Developmental and comparative immunology

authors： Li J,Yan C,Liu J,Yan J,Feng H

更新日期：2019-01-01 00:00:00

abstract：:C-type lectins play important roles in innate immunity of invertebrates. In the present study, we report a novel C-type lectin, named FcLec4, from the Chinese white shrimp Fenneropenaeus chinensis. FcLec4 contains a single carbohydrate recognition domain (CRD) with a putative signal peptide. Phylogenetic analysis indi...

journal_title：Developmental and comparative immunology

authors： Wang XW,Zhang XW,Xu WT,Zhao XF,Wang JX

更新日期：2009-09-01 00:00:00

abstract：:A five-domain Kazal-type serine proteinase inhibitor, SPIPm2, from Penaeus monodon has recently been implicated in antiviral responses for it is up-regulated upon viral infection and needs further studies. The SPIPm2 genomic gene was composed of seven exons and six introns. The genomic DNA segments coding for each Kaz...

journal_title：Developmental and comparative immunology

authors： Donpudsa S,Ponprateep S,Prapavorarat A,Visetnan S,Tassanakajon A,Rimphanitchayakit V

更新日期：2010-10-01 00:00:00

abstract：:Tumor necrosis factor (TNF) is one of the most important cytokines involved in many processes in both vertebrate and invertebrate. In the present study, a new tumor necrosis factor with a typical TNF domain was identified in oyster Crassostrea gigas (designated CgTNF-1). CgTNF-1 shared low sequence identity and simila...

journal_title：Developmental and comparative immunology

authors： Sun Y,Zhou Z,Wang L,Yang C,Jianga S,Song L

更新日期：2014-08-01 00:00:00

abstract：:This discussion is on immune response to Amyloodinium ocellatum, Cryptobia salmositica, Trypanoplasma borreli and Trypanosoma carassii. Piscidin and histone-like proteins enhance innate resistance to Amyloodinium. Fish that are naturally resistant to Cryptobia and Trypanoplasma can be bred. Cryptobia resistance in cha...

journal_title：Developmental and comparative immunology

authors： Woo PT,Ardelli BF

更新日期：2014-04-01 00:00:00

abstract：:In order to integrate evolutionary concepts into lymphoma research we mapped features of classic Hodgkin lymphoma (a disease which has been recently described to be derived from germinal center B-cells) onto a phylogenetic tree of vertebrates. Secondly, we matched the phylogenetic occurrence of classic Hodgkin lymphom...

journal_title：Developmental and comparative immunology

authors： Seitz V,Hummel M,Walter J,Stein H

更新日期：2003-01-01 00:00:00

abstract：:During Anuran metamorphosis larval structures regress, adult structures form anew and impaired T cell immune functions are noted, as are alterations in endogenous glucocorticoid titers. In situ histological data, after staining for DNA fragmentation, reveal patterns of lymphocyte suicide in the thymus and spleen of no...

journal_title：Developmental and comparative immunology

authors： Grant P,Clothier RH,Johnson RO,Ruben LN

更新日期：1998-07-01 00:00:00

abstract：:Cathepsins belongs to the cysteine protease family, which are activated by an acidic environment. They play essential biological roles in the innate immunity and development of animals. Here, we identified a 62 kDa cathepsin L-like protease from the silkworm Bombyx mori. It contained putative conserved domains, includ...

journal_title：Developmental and comparative immunology

authors： Sun YX,Chen C,Xu WJ,Abbas MN,Mu FF,Ding WJ,Zhang HJ,Li J

更新日期：2021-03-01 00:00:00

abstract：:The extension of comparative immunology to non-model systems, such as mollusks and annelids, has revealed an unexpected diversity in the complement of immune receptors and effectors among evolutionary lineages. However, several lophotrochozoan phyla remain unexplored mainly due to the lack of genomic resources. The in...

journal_title：Developmental and comparative immunology

authors： Gerdol M,Luo YJ,Satoh N,Pallavicini A

更新日期：2018-05-01 00:00:00

abstract：:A hepcidin-like gene (cmHep) was cloned and characterized from the liver of the blotched snakehead Channa maculata. The complete cmHep cDNA was 756 bp in length, containing an open reading frame of 270 bp (encoding 89 amino acids), flanked by 210 bp and 276 bp of 5' and 3' untranslated regions, respectively. The deduc...

journal_title：Developmental and comparative immunology

authors： Gong LC,Wang H,Deng L

更新日期：2014-05-01 00:00:00

abstract：:The effects of stress on immune activity and growth in early vertebrates have not been studied in detail. The present study used fine flounder (Paralichthys adspersus) skeletal muscle as a model to evaluate molecules involved in the stress response, including the glucocorticoid receptors, foxo1/3, and the target genes...

journal_title：Developmental and comparative immunology

authors： Valenzuela CA,Escobar D,Perez L,Zuloaga R,Estrada JM,Mercado L,Valdés JA,Molina A

更新日期：2015-11-01 00:00:00

abstract：:Horses greater than 20 years of age exhibit alterations in their immune responses similar to those observed in other aged individuals. The purpose of this study was to characterize immunosenescence in a population of aged ponies. The peripheral blood mononuclear cells (PBMC) from aged ponies exhibited a decreased prol...

journal_title：Developmental and comparative immunology

authors： Horohov DW,Kydd JH,Hannant D

更新日期：2002-01-01 00:00:00

abstract：:The ingestion of sheep erythrocytes (E) coated with specific IgM antibody (EA) and various purified human complement components (EAC 1, EAC 14, EAC 142, EAC 1423b, EAC 43b) by echinoid phagocytes was examined. E, EA, EAC 1, EAC 14 and EAC 142 were ingested at a similar and very low level, while a strong opsonic effect...

journal_title：Developmental and comparative immunology

authors： Bertheussen K

更新日期：1982-10-01 00:00:00

abstract：:Surfactant Protein A (SP-A) is a collagenous C-type lectin (collectin) that plays an important role in the early stage of the host immune response. In chicken, SP-A (cSP-A) is expressed as a 26 kDa glycosylated protein in the lung. Using immunohistochemistry, cSP-A protein was detected mainly in the lung lining fluid ...

journal_title：Developmental and comparative immunology

authors： Zhang W,Cuperus T,van Dijk A,Skjødt K,Hansen S,Haagsman HP,Veldhuizen EJ

更新日期：2016-08-01 00:00:00

abstract：:Allorecognition has been well-studied in the context of vertebrate adaptive immunity and recognition of the Major Histocompatibility Complex (MHC), which is the central event of vertebrate immune responses. Although allorecognition systems have been identified throughout the metazoa, recent results have shown that the...

journal_title：Developmental and comparative immunology

authors： Taketa DA,De Tomaso AW

更新日期：2015-01-01 00:00:00

abstract：:Resistance to Marek's disease (MD) in chickens is genetically regulated and there are lines of chickens with differential susceptibility or resistance to this disease. The present study was designed to study comparative changes in the spleen proteomes of MD-susceptible B19 and MD-resistant B21 chickens in response to ...

journal_title：Developmental and comparative immunology

authors： Thanthrige-Don N,Parvizi P,Sarson AJ,Shack LA,Burgess SC,Sharif S

更新日期：2010-07-01 00:00:00

abstract：:Variously colored abalone (Haliotis diversicolor Reeve, 1846), which is an important commercial aquatic species and has been widely cultured, frequently suffers from bacterial infection. Knowledge of the defense mechanism in this animal is still lacking and, so far few genes related to immune responses in abalones hav...

journal_title：Developmental and comparative immunology

authors： Wang KJ,Ren HL,Xu DD,Cai L,Yang M

更新日期：2008-01-01 00:00:00