当前位置： SCI文献检索 > DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY期刊下所有文献 > PcLys-i3, an invertebrate lysozyme, is involved in the antibacterial immunity of the red swamp crayfish, Procambarus clarkii.

PcLys-i3, an invertebrate lysozyme, is involved in the antibacterial immunity of the red swamp crayfish, Procambarus clarkii.

Abstract：

:Antimicrobial peptides (AMPs) play important roles in innate immunity against pathogens and lysozymes are a particularly type of AMP. Lysozymes are hydrolytic enzymes that are characterized by their ability to cleave the beta-(1,4)-glycosidic bond between N-acetylmuramic acid and N-acetylglucosamine in peptidoglycan, which is the major bacterial cell wall polymer. In this work, a lysozyme was identified from Procambarus clarkii and designated PcLys-i3. Quantitative RT-PCR was used to analyze the tissue distribution and expression profiles of PcLys-i3. PcLys-i3 was present in all tested tissues and had high expression levels in gills, stomach and intestine. The expression levels of PcLys-i3 were up-regulated in gills and intestine after challenge with Vibrio parahaemolyticus, Staphylococcus aureus and Aeromonas hydrophila. PcLys-i3 and PcFer proteins can enhance the bacterial elimination in crayfish, whereas the bacterial elimination was weakened when the expression level of PcLys-i3 or PcFer RNAs was suppressed by RNAi. Recombinant PcLys-i3 and PcFer significantly reduced the mortality of crayfish with bacterial infections. Further study found that PcLys-i3 could interact with PcFer in vitro. Finally, the PcLys-i3 and PcFer proteins could bind to bacteria and inhibit bacterial replication. These results suggest that both PcLys-i3 and PcFer play important roles in the antibacterial immunity of red swamp crayfish.

journal_name

Dev Comp Immunol

journal_title

Developmental and comparative immunology

authors

Liu Y,Zhang YH,Li T,Cao XT,Zhou Y,Yuan JF,Gu ZM,Lan JF

doi

10.1016/j.dci.2018.05.020

subject

Has Abstract

pub_date

2018-10-01 00:00:00

pages

109-115

eissn

0145-305X

issn

1879-0089

pii

S0145-305X(17)30627-4

journal_volume

87

pub_type

杂志文章

相关文献

DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY文献大全
  • HMGB3 modulates ROS production via activating TLR cascade in Apostichopus japonicus.

    abstract：:High mobility group box protein 3 (HMGB3) regulates proliferation and inflammatory response in vertebrates. However, its functional roles in invertebrates are largely unknown. In this study, a HMGB3 homologue molecule was identified from Apostichopus japonicus (designated as AjHMGB3) by RACE approach. The full-length ...

    journal_title：Developmental and comparative immunology

    pub_type： 杂志文章

    doi：10.1016/j.dci.2017.07.026

    authors： Lv Z,Zhang Z,Wei Z,Li C,Shao Y,Zhang W,Zhao X,Xiong J

    更新日期：2017-12-01 00:00:00

  • Molecular characterisation, evolution and expression analysis of g-type lysozymes in Ciona intestinalis.

    abstract：:Lysozyme is an important defense molecule of the innate immune system. Known for its bactericidal properties, lysozyme catalyzes the hydrolysis of b-(1,4)-glycosidic bonds between the N-acetyl glucosamine and N-acetyl muramic acid in the peptidoglycan layer of bacterial cell walls. In this study, the complete coding s...

    journal_title：Developmental and comparative immunology

    pub_type： 杂志文章

    doi：10.1016/j.dci.2016.09.010

    authors： Di Falco F,Cammarata M,Vizzini A

    更新日期：2017-02-01 00:00:00

  • Sex-associated differences in the mitogenic responsiveness of snake blood lymphocytes.

    abstract：:The blastogenic response of male and female snake (Psammophis sibilans) peripheral blood lymphocytes to concanavalin A, phytohaemagglutinin, and E. coli lipopolysaccharide was tested for putative sex-associated differences. Data obtained suggest that normal female blood lymphocytes respond relatively vigorous in compa...

    journal_title：Developmental and comparative immunology

    pub_type： 杂志文章

    doi：10.1016/0145-305x(89)90003-7

    authors： Saad AH

    更新日期：1989-07-01 00:00:00

  • Localization and bacteriostasis of Vibrio introduced into the Pacific white shrimp, Litopenaeus vannamei.

    abstract：:Although numerous mechanisms of immune defense have been described in crustaceans, the tissue distribution and fate of live bacteria introduced into the host remain unclear. In the present study, Litopenaeus vannamei were injected with a sub-lethal dose of kanamycin-resistant Vibrio campbellii expressing green fluores...

    journal_title：Developmental and comparative immunology

    pub_type： 杂志文章

    doi：10.1016/j.dci.2005.01.004

    authors： Burgents JE,Burnett LE,Stabb EV,Burnett KG

    更新日期：2005-01-01 00:00:00

  • White blood cell profiles in amphibians help to explain disease susceptibility following temperature shifts.

    abstract：:Temperature variability, and in particular temperature decreases, can increase susceptibility of amphibians to infections by the fungus Batrachochytrium dendrobatidis (Bd). However, the effects of temperature shifts on the immune systems of Bd-infected amphibians are unresolved. We acclimated frogs to 16 °C and 26 °C ...

    journal_title：Developmental and comparative immunology

    pub_type： 杂志文章

    doi：10.1016/j.dci.2017.08.018

    authors： Greenspan SE,Bower DS,Webb RJ,Berger L,Rudd D,Schwarzkopf L,Alford RA

    更新日期：2017-12-01 00:00:00

  • Infection with the trypanosome Crithidia bombi and expression of immune-related genes in the bumblebee Bombus terrestris.

    abstract：:Social bees and other insects are frequently parasitized by a large range of different microorganisms. Among these is Crithidia bombi (Kinetoplastida: Trypanosomatidae), a common gut parasite of bumblebees, Bombus spp. (Insecta: Apidae). Bumblebees are important pollinators in commercial and natural environments. Ther...

    journal_title：Developmental and comparative immunology

    pub_type： 杂志文章

    doi：10.1016/j.dci.2010.02.002

    authors： Schlüns H,Sadd BM,Schmid-Hempel P,Crozier RH

    更新日期：2010-07-01 00:00:00

  • Studies on colony specificity in the compound ascidian, Botryllus primigenus Oka. II. In vivo bioassay for analyzing the mechanism of "nonfusion" reaction.

    abstract：:Fusion experiments with three colonies (AC-BC-BD) by Tanaka and Watanabe indicated that the mixture of blood from two nonfusible colonies induced a "nonfusion" reaction (NFR)-like responses. Thus, artificial mixture of the blood from two nonfusible colonies is expected to result in NFR-like reactions. The present stud...

    journal_title：Developmental and comparative immunology

    pub_type： 杂志文章

    doi：10.1016/s0145-305x(82)80007-4

    authors： Taneda Y,Watanabe H

    更新日期：1982-04-01 00:00:00

  • Humoral immunoglobulins of the white sturgeon, Acipenser transmontanus: partial characterization of and recognition with monoclonal antibodies.

    abstract：:White sturgeon (Acipenser transmontanus) immunoglobulin (Ig) was purified from serum by two methods, ion-exchange chromatography and gel filtration and precipitation of the euglobulin fraction. The purity of these immunoglobulin preparations was confirmed by gel electrophoresis. Sequence analysis of the N-terminal ami...

    journal_title：Developmental and comparative immunology

    pub_type： 杂志文章

    doi：10.1016/0145-305x(96)00015-8

    authors： Adkison MA,Basurco B,Hedrick RP

    更新日期：1996-07-01 00:00:00

  • Identification and molecular characterization of a complement C3 molecule in a lophotrochozoan, the Hawaiian bobtail squid Euprymna scolopes.

    abstract：:Examination of the EST database of the light organ of the Hawaiian bobtail squid Euprymna scolopes revealed a sequence with similarity to complement C3. RACE yielded the full open reading frame of this protein. Analysis of the resultant sequence revealed that Es-C3 (E. scolopes-C3) has conserved residues and domains k...

    journal_title：Developmental and comparative immunology

    pub_type： 杂志文章

    doi：10.1016/j.dci.2008.07.013

    authors： Castillo MG,Goodson MS,McFall-Ngai M

    更新日期：2009-01-01 00:00:00

  • The gene encoding the sea urchin complement protein, SpC3, is expressed in embryos and can be upregulated by bacteria.

    abstract：:Sea urchins have an innate immune response that functions in the absence of adaptive capabilities. It is mediated, in part, by components of the complement system, an important subsystem of the innate response in mammals. A homologue of complement C3, SpC3, has been identified in adult Strongylocentrotus purpuratus an...

    journal_title：Developmental and comparative immunology

    pub_type： 杂志文章

    doi：10.1016/s0145-305x(03)00030-2

    authors： Shah M,Brown KM,Smith LC

    更新日期：2003-06-01 00:00:00

  • The first report of siglec-3/CD33 gene in a teleost (rock bream, Oplegnathus fasciatus): An analysis of its spatial expression during stimulation to red seabream iridovirus (RSIV) and two bacterial pathogens.

    abstract：:Siglec-3/CD33 is a myeloid-specific inhibitory receptor that is expressed on cells of the immune system, where it is believed to play a regulatory role, modulating the inflammatory and immune responses. We characterized CD33 (RbCD33) in rock bream which is a transmembrane protein with two IG-like domains and a cytopla...

    journal_title：Developmental and comparative immunology

    pub_type： 杂志文章

    doi：10.1016/j.dci.2018.02.005

    authors： Jeswin J,Joo MS,Jeong JM,Bae JS,Choi KM,Cho DH,Park SI,Park CI

    更新日期：2018-07-01 00:00:00

  • Identification and characterization of chicken interleukin-16 cDNA.

    abstract：:Interleukin-16 is an inflammatory cytokine synthesized as a precursor protein (pro-IL-16). Based on sequence data from an EST cDNA library prepared from intestinal intraepithelial lymphocytes of Eimeria-infected chickens, we identified a cDNA that contained a full-length open reading frame of pro-IL-16. The encoded pr...

    journal_title：Developmental and comparative immunology

    pub_type： 杂志文章

    doi：10.1016/s0145-305x(03)00133-2

    authors： Min W,Lillehoj HS

    更新日期：2004-02-01 00:00:00

  • Single and mixed-species trypanosome and microsporidia infections elicit distinct, ephemeral cellular and humoral immune responses in honey bees.

    abstract：:Frequently encountered parasite species impart strong selective pressures on host immune system evolution and are more apt to concurrently infect the same host, yet molecular impacts in light of this are often overlooked. We have contrasted immune responses in honey bees to two common eukaryotic endoparasites by estab...

    journal_title：Developmental and comparative immunology

    pub_type： 杂志文章

    doi：10.1016/j.dci.2013.03.010

    authors： Schwarz RS,Evans JD

    更新日期：2013-07-01 00:00:00

  • Spatial and temporal transcriptomic analyses reveal locust initiation of immune responses to Metarhizium acridum at the pre-penetration stage.

    abstract：:Insect hemocyte and fat body tissues play critical functional roles in insect immunity. Little, however, is known concerning the dynamic responses of these tissues to fungal infection. Here, we report on a time course of locust hemocyte and fat body transcriptomic responses to infection by the acridid specific fungal ...

    journal_title：Developmental and comparative immunology

    pub_type： 杂志文章

    doi：10.1016/j.dci.2019.103524

    authors： Zhang W,Zheng X,Chen J,Keyhani NO,Cai K,Xia Y

    更新日期：2020-03-01 00:00:00

  • Development and adaptations of innate immunity in the gastrointestinal tract of the newly hatched chick.

    abstract：:The intestinal immune system in Gallus species must rapidly adapt to the omnivorous onset of an adult diet and to colonization by commensal bacteria. Yet, acquired immune functions in Gallus digestive tract fully develop only towards the end of the first week post-hatch. This raises the question of immune protection i...

    journal_title：Developmental and comparative immunology

    pub_type： 杂志文章

    doi：10.1016/j.dci.2005.12.002

    authors： Bar-Shira E,Friedman A

    更新日期：2006-01-01 00:00:00

  • Molecular identification and function characterization of four finTRIM genes from the immortal fish cell line, EPC.

    abstract：:In mammals, tripartite motif (TRIM)-containing proteins are involved in interferon (IFN)-mediated antiviral response as pivotal players endowed with antiviral effects and modulatory capacity. Teleost fish have a unique subfamily of TRIM, called finTRIM (fish novel TRIM, FTR) generated by genus- or species-specific dup...

    journal_title：Developmental and comparative immunology

    pub_type： 杂志文章

    doi：10.1016/j.dci.2020.103775

    authors： Li YL,Zhao X,Gong XY,Dan C,Gui JF,Zhang YB

    更新日期：2020-12-01 00:00:00

  • D1 dopamine receptor is involved in shell formation in larvae of Pacific oyster Crassostrea gigas.

    abstract：:Dopamine (DA), a significant member of catecholamines, is reported to induce biomineralization of calcium carbonate vaterite microspheres via dopamine receptor (DR) in bivalves, implying the modulation of dopaminergic system on shell formation during larval development. In this research, a homologue of D1 type DR (CgD...

    journal_title：Developmental and comparative immunology

    pub_type： 杂志文章

    doi：10.1016/j.dci.2018.03.009

    authors： Liu Z,Wang L,Yan Y,Zheng Y,Ge W,Li M,Wang W,Song X,Song L

    更新日期：2018-07-01 00:00:00

  • The degree of postpartum metabolic challenge in dairy cows is associated with peripheral blood mononuclear cell transcriptome changes of the innate immune system.

    abstract：:Dairy cows undergo a nutrient deficit immediately postpartum when lactational demands exceed nutrient intake. This occurs concurrently to an increased challenge due to bacterial and viral infections, yet ability for pathogen clearance is reduced despite a heightened and often host-damaging inflammatory response. We hy...

    journal_title：Developmental and comparative immunology

    pub_type： 杂志文章

    doi：10.1016/j.dci.2018.11.021

    authors： Mann S,Sipka AS,Grenier JK

    更新日期：2019-04-01 00:00:00

  • An alternative internal splicing site defines new Ikaros isoforms in Pleurodeles waltl.

    abstract：:The Ikaros gene encodes a family of transcription factors which plays a crucial role in hematopoiesis. To improve our knowledge about the immune system of Pleurodeles waltl, we sequenced the cDNA coding for the Ik-1 isoform of that salamander and analyzed its tissue expression by semi-quantitative RT-PCR. Ikaros trans...

    journal_title：Developmental and comparative immunology

    pub_type： 杂志文章

    doi：10.1016/s0145-305x(02)00014-9

    authors： Boudarra N,Frippiat C,Dournon C,Frippiat JP

    更新日期：2002-09-01 00:00:00

  • Suppression of Salmonella enterica serovar Enteritidis excretion by intraocular vaccination with fimbriae proteins incorporated in liposomes.

    abstract：:Liposome-associated fimbriae antigens (SEF14 and SEF21) were prepared for intraocular immunization to seek protective efficacy for intestinal infection with Salmonella enterica serovar Enteritidis. Chickens were immunized intraocularly with the antigens at 8 and 10 weeks of age. Evidence of an IgA and IgG responses we...

    journal_title：Developmental and comparative immunology

    pub_type： 杂志文章

    doi：10.1016/s0145-305x(03)00086-7

    authors： Li W,Watarai S,Iwasaki T,Kodama H

    更新日期：2004-01-01 00:00:00

  • In vitro production of hydrogen peroxide by the amoebocytes of the scallop, Patinopecten yessoensis (Jay).

    abstract：:In vitro production of hydrogen peroxide (H2O2) by the amoebocytes of the scallop, Patinopecten yessoensis, was studied. The authors first confirmed the availability of the direct quantitative method using homovanillic acid, and found that both resting and stimulated amoebocytes produced H2O2. However, the latter show...

    journal_title：Developmental and comparative immunology

    pub_type： 杂志文章

    doi：10.1016/0145-305x(85)90004-7

    authors： Nakamura M,Mori K,Inooka S,Nomura T

    更新日期：1985-07-01 00:00:00

  • Atlantic salmon IPS-1 mediates induction of IFNa1 and activation of NF-kappaB and localizes to mitochondria.

    abstract：:The striking difference in evolution of type I IFN genes of fish and mammals poses the question of whether these genes are induced through similar or different signalling pathways in the two vertebrate groups. Previous work has shown that expression of both Atlantic salmon (Salmo salar) IFNa1 and mammalian IFN-beta ge...

    journal_title：Developmental and comparative immunology

    pub_type： 杂志文章

    doi：10.1016/j.dci.2009.06.012

    authors： Lauksund S,Svingerud T,Bergan V,Robertsen B

    更新日期：2009-11-01 00:00:00

  • Functional studies on Calliphora vomitoria haemocyte subpopulations defined by lectin staining and density centrifugation.

    abstract：:Haemocyte subpopulations of Calliphora vomitoria have been categorized by their surface staining properties using fluorescently labelled lectins, and their mobilities in Percoll density gradients. These methods of identification were exploited to determine the roles of these cell types in cellular defence reactions. S...

    journal_title：Developmental and comparative immunology

    pub_type： 杂志文章

    doi：10.1016/0145-305x(92)90048-h

    authors： McKenzie AN,Preston TM

    更新日期：1992-01-01 00:00:00

  • The sensing pattern and antitoxic response of Crassostrea gigas against extracellular products of Vibrio splendidus.

    abstract：:Serious juvenile oyster disease induced by pathogenic Vibrio splendidus has resulted in tremendous economic loss, but the molecular mechanisms underlying this killing mechanism remain unclear. The resistance of adult oyster to V. splendidus or its virulence factors might provide a possible access to cognize the intera...

    journal_title：Developmental and comparative immunology

    pub_type： 杂志文章

    doi：10.1016/j.dci.2019.103467

    authors： Wang W,Lv X,Liu Z,Song X,Yi Q,Wang L,Song L

    更新日期：2020-01-01 00:00:00

  • Silkworm ferritin 1 heavy chain homolog is involved in defense against bacterial infection through regulation of haemolymph iron homeostasis.

    abstract：:Iron functions as a nutrient and a potential toxin in all organisms. It plays a key role in the interaction between microbes and their hosts as well. Microbial infection disrupts iron homeostasis in the host; meanwhile the host endeavors to keep the homeostasis through iron transport and storage. Transferrins and ferr...

    journal_title：Developmental and comparative immunology

    pub_type： 杂志文章

    doi：10.1016/j.dci.2015.10.022

    authors： Otho SA,Chen K,Zhang Y,Wang P,Lu Z

    更新日期：2016-02-01 00:00:00

  • Carbohydrate binding specificity and purification by biospecific affinity chromatography of Ascidia malaca Traust. hemagglutinins.

    abstract：:The carbohydrate specificities of Ascidia malaca serum hemagglutinins were determined by hemagglutination inhibition tests. Analysis of agglutinins against rabbit and human A, B, O erythrocytes suggests that the size of the combining site corresponds to a disaccharide with a specificity for saccharides containing a D...

    journal_title：Developmental and comparative immunology

    pub_type： 杂志文章

    doi：10.1016/0145-305x(82)90007-6

    authors： Parrinello N,Canicattì C

    更新日期：1982-01-01 00:00:00

  • Genetics of anti-parasite resistance in invertebrates.

    abstract：:This review summarizes and compares available data on genetic and molecular aspects of resistance in four well-described invertebrate host-parasite systems: snail-schistosome, mosquito-malaria, mosquito-filarial worm, and Drosophila-wasp associations. It underlies that the major components of the immune reaction, such...

    journal_title：Developmental and comparative immunology

    pub_type： 杂志文章,评审

    doi：10.1016/j.dci.2004.05.004

    authors： Carton Y,Nappi AJ,Poirie M

    更新日期：2005-01-01 00:00:00

  • Molecular characterization and expression analysis of four isotypes of immunoglobulin light chain genes in orange-spotted grouper, Epinephelus coioides.

    abstract：:To date, many immunoglobulin (Ig) genes have been identified in diverse teleost species, but the contributions of different types of light chain (IgL) to the immune response remain unclear. Screening of a stimulated kidney cDNA library from orange-spotted grouper (Osg, Epinephelus coioides) resulted in the identificat...

    journal_title：Developmental and comparative immunology

    pub_type： 杂志文章

    doi：10.1016/j.dci.2012.11.003

    authors： Wu MS,Cheng CA,Lin CH,Lee CY,Tseng SJ,Tzeng CS,Chang CY

    更新日期：2013-03-01 00:00:00

  • Molecular characterization and expression analysis of TLR1 and TLR4 from the endangered fish Dabry's sturgeon (Acipenser dabryanus).

    abstract：:Toll-like receptors (TLRs) are important pattern recognition receptors (PRRs) of teleost innate immune system. However, information about TLRs is absent in Dabry's sturgeon (Acipenser dabryanus), one of the most primitive actinopterygii species. In the present study, the full lengths of adaTLR1 and adaTLR4 were cloned...

    journal_title：Developmental and comparative immunology

    pub_type： 杂志文章

    doi：10.1016/j.dci.2018.05.009

    authors： Han P,Wang S,Zhang Q,Zhang S,Shao R,Xu W,Zhang W,Xu Q,Wei Q,Qi Z

    更新日期：2018-09-01 00:00:00

  • The M2 macrophages induce autophagic vascular disorder and promote mouse sensitivity to urethane-related lung carcinogenesis.

    abstract：:Tumor vessels are known to be abnormal, with typically aberrant, leaky and disordered vessels. Here, we investigated whether polarized macrophage phenotypes are involved in tumor abnormal angiogenesis and what is its mechanism. We found that there was no difference in chemotaxis of polarized M1 and M2 macrophages to l...

    journal_title：Developmental and comparative immunology

    pub_type： 杂志文章

    doi：10.1016/j.dci.2016.01.010

    authors： Li GG,Guo ZZ,Ma XF,Cao N,Geng SN,Zheng YQ,Meng MJ,Lin HH,Han G,Du GJ

    更新日期：2016-06-01 00:00:00