The bovine genomic DNA sequence data reveal three IGHV subgroups, only one of which is functionally expressed.

abstract：:Interleukin 1b (IL-1b) is a member of the cytokine family that serves as major mediators for early pro-inflammatory responses. During artificial breeding of Pacific cod (Gadus macrocephalus), outbreaks of NNV in the early development stages could lead to high mortality. Recent research reported that IL-1b participated...

journal_title：Developmental and comparative immunology

authors： Hu B,Chen B,Mao M,Chen M,Liu X,Cui Q,Liu Y,Jiang C

更新日期：2018-11-01 00:00:00

abstract：:Lysozymes as an important immune factor, play vital roles in innate immune response against pathogen infection. In the present study, one c-type and g-type lysozymes were identified from Chinese giant salamander (Andrias davidianus). They shared highly conserved structural features with lysozymes from other species. S...

journal_title：Developmental and comparative immunology

authors： Yang H,Liu R,Cui D,Liu H,Xiong D,Liu X,Wang L

更新日期：2017-07-01 00:00:00

abstract：:Surfactant Protein A (SP-A) is a collagenous C-type lectin (collectin) that plays an important role in the early stage of the host immune response. In chicken, SP-A (cSP-A) is expressed as a 26 kDa glycosylated protein in the lung. Using immunohistochemistry, cSP-A protein was detected mainly in the lung lining fluid ...

journal_title：Developmental and comparative immunology

authors： Zhang W,Cuperus T,van Dijk A,Skjødt K,Hansen S,Haagsman HP,Veldhuizen EJ

更新日期：2016-08-01 00:00:00

abstract：:We recently reported that D-alanylation of Staphylococcus aureus wall teichoic acid (WTA) mitigates an induction of the Toll-mediated humoral response in Drosophila by interfering with peptidoglycan (PG) recognition by PG recognition protein-SA (PGRP-SA). Here, we investigated the mode of this interference by using an...

journal_title：Developmental and comparative immunology

authors： Kurokawa K,Gong JH,Ryu KH,Zheng L,Chae JH,Kim MS,Lee BL

更新日期：2011-08-01 00:00:00

abstract：:The chemokine RANTES plays an essential role in inflammation and immune response. In this study, we cloned the nucleotide sequence of the 5'-flanking region of the porcine RANTES (poRANTES) gene and characterized the regulatory elements that activate transcription. Analyses of a series of 5' deletion constructs demons...

journal_title：Developmental and comparative immunology

authors： Wang D,Fang L,Li P,Chen Q,Luo R,Chen H,Xiao S

更新日期：2011-03-01 00:00:00

abstract：:FoxP3 is a transcription factor essential for differentiation and function of T regulatory cells (Tregs). There are two major subsets of Tregs: natural Tregs (nTregs) generated in thymus and inducible Tregs (iTregs) produced in peripheral immune system. It has been documented that iTreg development is dependent on sol...

journal_title：Developmental and comparative immunology

authors： Ilnicka A,Gocek E,Łopatecka J,Marcinkowska E

更新日期：2019-07-01 00:00:00

abstract：:Spleen and thymus suspensions from the turtle, Chelydra serpentina were examined by indirect immunofluorescence and found to contain both agranulocytes and granulocytes positive for surface Ig. Among the splenic agranulocytes , 50% of the lymphocyte and monocyte population was positive for surface Ig. In the thymus on...

journal_title：Developmental and comparative immunology

authors： Mead KF,Borysenko M

更新日期：1984-01-01 00:00:00

abstract：:Next generation sequencing (NGS) allows for the rapid, comprehensive and cost effective analysis of entire genomes and transcriptomes. NGS provides approaches for immune response gene discovery, profiling gene expression over the course of parasitosis, studying mechanisms of diversification of immune receptors and inv...

journal_title：Developmental and comparative immunology

authors： Dheilly NM,Adema C,Raftos DA,Gourbal B,Grunau C,Du Pasquier L

更新日期：2014-07-01 00:00:00

abstract：:Type I interferon (IFN) induces the antiviral response in innate immunity. The type I IFN gene cloned from Japanese flounder (Paralichthys olivaceus) has a length of 1189 bp and consisting of 5 exons and 4 introns. In a phylogenetic tree of type I IFNs, Japanese flounder grouped with other Acanthopterygii. To gain ins...

journal_title：Developmental and comparative immunology

authors： Ohtani M,Hikima J,Hwang SD,Morita T,Suzuki Y,Kato G,Kondo H,Hirono I,Jung TS,Aoki T

更新日期：2012-04-01 00:00:00

abstract：:Transfection is a powerful tool useful for studying gene function. Establishing transfection methods that enable highly efficient DNA uptake has become increasingly important. The crayfish hematopoietic tissue (Hpt) cell cultures have been proven to be suitable for studies on immunity and cell differentiation in crust...

journal_title：Developmental and comparative immunology

authors： Shi H,Ruan L,Söderhäll I,Söderhäll K,Xu X

更新日期：2018-11-01 00:00:00

abstract：:While genetic evidence points towards an absence of Toll-Like Receptors (TLRs) in Platyhelminthes, the Toll/IL-1 Receptor (TIR)-domains that drive the assembly of signalling complexes downstream TLR are present in these organisms. Here, we undertook the characterisation of the repertoire of TIR-domain containing prote...

journal_title：Developmental and comparative immunology

authors： Tsoumtsa LL,Sougoufara S,Torre C,Lemichez E,Pontarotti P,Ghigo E

更新日期：2018-09-01 00:00:00

abstract：:Immunofluorescence studies of bream lymphoid tissues revealed that our 90% of the lymphocytes from blood, anterior kidney, spleen and thymus exhibited membrane immunoglobulin determinants. Furthermore, a majority of such cells were observed to undergo patching and capping when the membrane proteins were complexed with...

journal_title：Developmental and comparative immunology

authors： Clem LW,McLean WE,Shankey VT,Cuchens MA

更新日期：1977-04-01 00:00:00

abstract：:Toll-like Receptors (TLRs) are the first innate receptors in recognizing pathogen-associated molecular patterns. In fish, upregulation of toll-like receptors during infection has been largely demonstrated while the effects of abiotic stressors on their expression remain poorly investigated. In this study, striped catf...

journal_title：Developmental and comparative immunology

authors： Schmitz M,Baekelandt S,Bequet S,Kestemont P

更新日期：2017-08-01 00:00:00

abstract：:Gilthead seabream and European sea bass are two of the most commonly farmed fish species. Larval development is critical to ensure high survival rates and thus avoid unacceptable economic losses, while nutrition and immunity are also important factors. For this reason this paper evaluates the ontogenetic development o...

journal_title：Developmental and comparative immunology

authors： Cordero H,Guzmán-Villanueva LT,Chaves-Pozo E,Arizcun M,Ascencio-Valle F,Cuesta A,Esteban MA

更新日期：2016-12-01 00:00:00

abstract：:The skin mucus of the conger eel, Conger myriaster, contains galactose-specific agglutinins. Hemagglutinating activity is independent of divalent cations and is destroyed by heating at 50 degrees C for 15 min. The mucus agglutinins, named congerins, are a mixture of proteins with different electrical charges. Three of...

journal_title：Developmental and comparative immunology

authors： Kamiya H,Muramoto K,Goto R

更新日期：1988-04-01 00:00:00

abstract：:Yellow head virus (YHV) is one of the most widespread viruses seriously affecting black tiger shrimp (Penaeus monodon) cultivation. A previous microarray study demonstrated that clathrin coat assembly protein 17 (AP17) was significantly up-regulated after YHV infection (Pongsomboon et al., 2011). Clathrin coat AP17 is...

journal_title：Developmental and comparative immunology

authors： Jatuyosporn T,Supungul P,Tassanakajon A,Krusong K

更新日期：2014-05-01 00:00:00

abstract：:Population declines due to chytridiomycosis among frogs belonging to the Amerana (Rana boylii) species group from western North America have been particularly severe. Norepinephrine-stimulated skin secretions from the Oregon spotted frog Rana pretiosa Baird and Girard, 1853 were collected from individuals that had bee...

journal_title：Developmental and comparative immunology

authors： Conlon JM,Mechkarska M,Ahmed E,Coquet L,Jouenne T,Leprince J,Vaudry H,Hayes MP,Padgett-Flohr G

更新日期：2011-06-01 00:00:00

abstract：:C-type lectins play important roles in innate immunity of invertebrates. In the present study, we report a novel C-type lectin, named FcLec4, from the Chinese white shrimp Fenneropenaeus chinensis. FcLec4 contains a single carbohydrate recognition domain (CRD) with a putative signal peptide. Phylogenetic analysis indi...

journal_title：Developmental and comparative immunology

authors： Wang XW,Zhang XW,Xu WT,Zhao XF,Wang JX

更新日期：2009-09-01 00:00:00

abstract：:To date, most studies on pinniped immunoglobulins have focused on circulating antibodies. However, systemic and local immune activities differ in terms of maturation, intensity, and types of effectors that participate. Here, we examined levels of three immunoglobulin isotypes, IgG, IgM and IgA, in the blood and mucosa...

journal_title：Developmental and comparative immunology

authors： Espinosa-de Aquino W,Bailey M,Acevedo-Whitehouse K

更新日期：2017-12-01 00:00:00

abstract：:Lectin is a protein with multiple functions. In this study, the full-length cDNA of the Agrocybe aegerita lectin (AAL) gene was cloned, recombinant AAL (AAL-His) was expressed, and the activities of AAL-His were analyzed. Northern blot analysis showed that the major AAL transcript is approximately 900 bp. Sequence ana...

journal_title：Developmental and comparative immunology

authors： Chang YS,Chen JN,Chang KH,Chang YM,Lai YJ,Liu WJ

更新日期：2019-01-01 00:00:00

abstract：:Woodchucks (Marmota monax) infected with woodchuck hepatitis virus (WHV) represent a highly valuable immunopathogenic model of hepatitis B virus (HBV) infection. Both WHV and HBV are noncytopathic hepadnaviruses which induce a strong but delayed virus-specific cellular immune response believed to be a cause of hepatit...

journal_title：Developmental and comparative immunology

authors： Gujar SA,Jenkins AK,Macparland SA,Michalak TI

更新日期：2010-09-01 00:00:00

abstract：:Social bees and other insects are frequently parasitized by a large range of different microorganisms. Among these is Crithidia bombi (Kinetoplastida: Trypanosomatidae), a common gut parasite of bumblebees, Bombus spp. (Insecta: Apidae). Bumblebees are important pollinators in commercial and natural environments. Ther...

journal_title：Developmental and comparative immunology

authors： Schlüns H,Sadd BM,Schmid-Hempel P,Crozier RH

更新日期：2010-07-01 00:00:00

abstract：:Toll-like receptors (TLRs) play an important role in the activation of innate and adaptive immune responses. Stimulation with multiple TLR agonists may result in synergistic, complimentary or inhibitory effects on innate immune responses. In this study, we investigated the effects of co-stimulation of sheep peripheral...

journal_title：Developmental and comparative immunology

authors： Booth JS,Buza JJ,Potter A,Babiuk LA,Mutwiri GK

更新日期：2010-05-01 00:00:00

abstract：:Viral virulence/immune evasion strategies and host anti-viral responses represent different sides of the continuing struggle between virus and host survival. To identify virus-encoding molecules whose function is to subvert or blunt host immune responses, we have adapted anti-sense approaches to knock down the express...

journal_title：Developmental and comparative immunology

authors： Whitley DS,Sample RC,Sinning AR,Henegar J,Chinchar VG

更新日期：2011-09-01 00:00:00

abstract：:Brief pretreatment of cold shock at 13 °C for 3 min proved to be an inducer of heat shock protein 70 (HSP70) and improved stress tolerance as a molecular chaperone. With the improvement of air exposure tolerance, HSP70 in shrimp hemocytes was upregulated in mRNA and protein levels after cold shock. Both HSP70 RNA inte...

journal_title：Developmental and comparative immunology

authors： Guan W,Wei X,Nong W,Shao Y,Mao L

更新日期：2021-01-01 00:00:00

abstract：:Corals form the framework of the world's coral reefs and are under threat from increases in disease and bleaching (symbiotic dysfunction), yet the mechanisms of pathogen and symbiont recognition remain largely unknown. Here we describe the isolation and characterisation of an ancient mannose-binding lectin in the cora...

journal_title：Developmental and comparative immunology

authors： Kvennefors EC,Leggat W,Hoegh-Guldberg O,Degnan BM,Barnes AC

更新日期：2008-01-01 00:00:00

abstract：:B cell activating factor belonging to the tumor necrosis factor (TNF) family (BAFF) is critical for B cell survival, maturation and T cell activation by acting through its three receptors, BAFF-R, BCMA and TACI. In the present study, a porcine BAFF cDNA, designated pBAFF, was cloned by RT-PCR and rapid amplification o...

journal_title：Developmental and comparative immunology

authors： Guan ZB,Dan WB,Shui Y,Ye JL,Zhang SQ

更新日期：2007-01-01 00:00:00

abstract：:Thymic non-lymphoid cells have been shown to influence the differentiation of T-lymphocytes. Large numbers of non-lymphoid cells are concentrated in the thymic medullary zone. A morphometric analysis of these cells in the medulla identified little change in their absolute number and volume density during thymic develo...

journal_title：Developmental and comparative immunology

authors： Higley HR,O'Morchoe CC

更新日期：1984-07-01 00:00:00

abstract：:IFN-λ (IFNL), i.e. type III IFN genes were found in a conserved gene locus in tetrapod vertebrates. But, a unique locus containing IFNL was found in avian. In turtle and crocodile, IFNL genes were distributed in these two separate loci. As revealed in phylogenetic trees, IFN-λs in these two different loci and other am...

journal_title：Developmental and comparative immunology

authors： Chen SN,Zhang XW,Li L,Ruan BY,Huang B,Huang WS,Zou PF,Fu JP,Zhao LJ,Li N,Nie P

更新日期：2016-08-01 00:00:00

abstract：:There is increasing concern about the possible effect of pharmaceutical compounds may have on the fish immune system. Bath exposition of 17α-ethynylestradiol (EE2), a synthetic estrogen used in oral contraceptives, altered the immune response of the gilthead seabream (Sparus aurata L.), a marine hermaphrodite teleost....

journal_title：Developmental and comparative immunology

authors： Rodenas MC,Cabas I,Abellán E,Meseguer J,Mulero V,García-Ayala A

更新日期：2015-12-01 00:00:00