Pre-acute hepadnaviral infection is associated with activation-induced apoptotic death of lymphocytes in the woodchuck (Marmota monax) model of hepatitis B.

abstract：:The IMD pathway signaling plays a pivotal role in the Drosophila defense against bacteria. During the last two decades, significant progress has been made in identifying the components and deciphering the molecular mechanisms underlying this pathway, including the means of bacterial sensing and signal transduction. Wh...

journal_title：Developmental and comparative immunology

authors： Kleino A,Silverman N

更新日期：2014-01-01 00:00:00

abstract：:Microsporidia are a group of fungi-like intracellular and unicellular parasites, which infect nearly all animals. As "master parasites", over 1400 microsporidian species have been described to date. Microsporidia infections in economical invertebrates (e.g., silkworm, shrimp) cause huge financial losses, while other m...

journal_title：Developmental and comparative immunology

authors： Pan G,Bao J,Ma Z,Song Y,Han B,Ran M,Li C,Zhou Z

更新日期：2018-06-01 00:00:00

abstract：:VHSV-induced genes (VIGs) were first identified in rainbow trout (Oncorhynchus mykiss) and subsequently isolated in a variety of fish. Recent studies have shown that most VIGs have immunological functions against pathogenic infections. However, most research has focused on Vig1, such that our present understanding of ...

journal_title：Developmental and comparative immunology

authors： Yeh YC,Hsu YJ,Chen YM,Lin HY,Yang HL,Chen TY,Wang HC

更新日期：2014-03-01 00:00:00

abstract：:The effects of stress on immune activity and growth in early vertebrates have not been studied in detail. The present study used fine flounder (Paralichthys adspersus) skeletal muscle as a model to evaluate molecules involved in the stress response, including the glucocorticoid receptors, foxo1/3, and the target genes...

journal_title：Developmental and comparative immunology

authors： Valenzuela CA,Escobar D,Perez L,Zuloaga R,Estrada JM,Mercado L,Valdés JA,Molina A

更新日期：2015-11-01 00:00:00

abstract：:Swine belong to the Order Artiodactyla and like mice and humans, express IgM, IgD, IgG, IgE and IgA antibodies but a larger number of IgG subclasses. Like rabbits and chickens, expressed V(H) genes belong to the ancestral V(H)3 family and only 5 comprise >80% of the pre-immune repertoire. Since they use primarily two ...

journal_title：Developmental and comparative immunology

authors： Butler JE,Sun J,Wertz N,Sinkora M

更新日期：2006-01-01 00:00:00

abstract：:C-type lectins play important roles in innate immunity of invertebrates. In the present study, we report a novel C-type lectin, named FcLec4, from the Chinese white shrimp Fenneropenaeus chinensis. FcLec4 contains a single carbohydrate recognition domain (CRD) with a putative signal peptide. Phylogenetic analysis indi...

journal_title：Developmental and comparative immunology

authors： Wang XW,Zhang XW,Xu WT,Zhao XF,Wang JX

更新日期：2009-09-01 00:00:00

abstract：:The NF-kappaB group of transcription factors play an important role in mediating immune responses in organisms as diverse as insects and mammals. The fruit fly Drosophila melanogaster express three closely related NF-kappaB-like transcription factors: Dorsal, Dif, and Relish. To study their roles in vivo, we used micr...

journal_title：Developmental and comparative immunology

authors： Pal S,Wu J,Wu LP

更新日期：2008-01-01 00:00:00

abstract：:Adult Xenopus laevis serum containing an anti-chicken erythrocyte antibody exhibits complement (C) activity by both the classical and the alternative pathways. Lytic activity is removed by heating serum to 50 degrees C for at least 20 min; it is also removed by polysaccharides and by 7.5 mM EDTA. The optimum temperatu...

journal_title：Developmental and comparative immunology

authors： McKnight BJ,Jurd RD

更新日期：1987-07-01 00:00:00

abstract：:Liposome-associated fimbriae antigens (SEF14 and SEF21) were prepared for intraocular immunization to seek protective efficacy for intestinal infection with Salmonella enterica serovar Enteritidis. Chickens were immunized intraocularly with the antigens at 8 and 10 weeks of age. Evidence of an IgA and IgG responses we...

journal_title：Developmental and comparative immunology

authors： Li W,Watarai S,Iwasaki T,Kodama H

更新日期：2004-01-01 00:00:00

abstract：:Cytotoxic morula cells (MCs) and phagocytes are the circulating immunocytes of the colonial ascidian Botryllus schlosseri: Both these cells can synthesise amyloid fibrils, supporting the idea that physiological amyloidogenesis is involved in inflammation and modulation of immune responses. Intriguingly, amyloid of B. ...

journal_title：Developmental and comparative immunology

authors： Franchi N,Ballarin L,Peronato A,Cima F,Grimaldi A,Girardello R,de Eguileor M

更新日期：2019-01-01 00:00:00

abstract：:Dendritic cells (DC) are antigen-presenting cells that can be classified into three major cell subsets: conventional DC1 (cDC1), cDC2 and plasmacytoid DCs (pDC), none of which have been identified in horses. Therefore, the objective of this study was to identify and characterize DC subsets in equine peripheral blood, ...

journal_title：Developmental and comparative immunology

authors： Ziegler A,Marti E,Summerfield A,Baumann A

更新日期：2016-12-01 00:00:00

abstract：:Chemokines refer to chemoattractant cytokines, which have crucial functions in inflammation and immune responses in multiple cellular processes. In the present study, we described the potential role of porcine CCL5 in embryo implantation and fetal-maternal environment during early pregnancy. We first carried out phylo...

journal_title：Developmental and comparative immunology

authors： Bae H,Lee JY,Song G,Lim W

更新日期：2020-02-01 00:00:00

abstract：:The interleukin-17 (IL-17) cytokine family plays a central role in the coordination of inflammatory responses. In fish species, three genes that have a similar homology to both IL-17A and IL-17F were designated IL-17A/F1, 2, and 3. In this study, we identified three IL-17A/F homologues (LycIL-17A/F1, 2, and 3) from la...

journal_title：Developmental and comparative immunology

authors： Ding Y,Ao J,Ai C,Chen X

更新日期：2016-02-01 00:00:00

abstract：:This article reviews the past and present scientific reports regarding Bithynia spp. focusing on the biology, ecology and life cycle of Bithynia snails and their responses to Opisthorchis viverrini infection. Moreover, new data regarding comparative molecular genomics and proteomic approaches have recently revealed no...

journal_title：Developmental and comparative immunology

authors： Suwannatrai K,Suwannatrai AT,Loukas A,Sotillo J

更新日期：2020-01-01 00:00:00

abstract：:The function and mechanism of chitinases in early embryonic development remain largely unknown. We show here that recombinant chitinase-3 (rChi3) is able to hydrolyze the artificial chitin substrate, 4-methylumbelliferyl-β-D-N,N',N″-triacetylchitotrioside, and to bind to and inhibit the growth of the fungus Candida al...

journal_title：Developmental and comparative immunology

authors： Teng Z,Sun C,Liu S,Wang H,Zhang S

更新日期：2014-10-01 00:00:00

abstract：:Duck (Anas platyrhynchos) blood lymphocytes were cultured in the presence of phytohaemagglutinin (PHA), concanavalin A (Con A), pokeweed mitogen (PWM), lentil lectin (LL), Roman snail lectin (HP), wheat germ agglutinin (WGA), Bandeiraea simplicifolia seed lectin (BSS), peanut agglutinin (PNA), horseshoe crab lectin (H...

journal_title：Developmental and comparative immunology

authors： Higgins DA

更新日期：1991-10-01 00:00:00

abstract：:An antigen preparation of Vibrio anguillarum, a salmonid pathogen, acts as a potent in vitro mitogenic stimulator of splenic and pronephric (anterior kidney) lymphocytes from coho salmon (Oncorhynchus kisutch), chinook salmon (O. tshawytscha) and rainbow trout (Salmo gairdneri). This antigen (VA) is comparable in its ...

journal_title：Developmental and comparative immunology

authors： Yui MA,Kaattari SL

更新日期：1987-07-01 00:00:00

abstract：:Infectious hematopoietic necrosis virus (IHNV) is a common pathogen that causes severe disease in the salmonid aquaculture industry. Recent work demonstrated that autophagy plays an important role in pathogen invasion by activating innate and adaptive immunity. This study investigated the relationship between IHNV and...

journal_title：Developmental and comparative immunology

authors： Zhao JZ,Xu LM,Liu M,Zhang ZY,Yin JS,Liu HB,Lu TY

更新日期：2017-12-01 00:00:00

abstract：:This review summarizes the scattered literature on the effects of toxicants on the external and internal innate immunity of fish. Insecticides, heavy metals and surfactants have been the most frequently examined toxicants, whereas dioxins, furans and polychlorinated biphenyls have been tested less frequently. Studies ...

journal_title：Developmental and comparative immunology

authors： Bols NC,Brubacher JL,Ganassin RC,Lee LE

更新日期：2001-10-01 00:00:00

abstract：:We investigated the effect of brown ring disease (BRD) development and algal diet on energy reserves and activity of enzymes related to energy metabolism, antioxidant system and immunity in Manila clam, Ruditapes philippinarum. We found that algal diet did not impact the metabolic response of clams exposed to Vibrio t...

journal_title：Developmental and comparative immunology

authors： Richard G,Guérard F,Corporeau C,Lambert C,Paillard C,Pernet F

更新日期：2016-07-01 00:00:00

abstract：:Toll-like receptors (TLRs)are pattern recognition receptors (PRRs) that are important in invertebrate innate immunity for the recognition and elimination of pathogens. Although they were reported in many fishes, Toll-like receptors subfamily contain a large number of members with different functions that need to resea...

journal_title：Developmental and comparative immunology

authors： Wu M,Zhu KC,Guo HY,Guo L,Liu B,Jiang SG,Zhang DC

更新日期：2021-04-01 00:00:00

abstract：:Avidin is well known for its high affinity to biotin and has been found in many egg-laying vertebrate species. However, little is known about avidin in invertebrate species to date. Here we clearly showed the presence of two avidin genes, Bjavidin1 and Bjavidin2, in the amphioxus Branchiostoma japonicum, the first one...

journal_title：Developmental and comparative immunology

authors： Guo X,Xin J,Wang P,Du X,Ji G,Gao Z,Zhang S

更新日期：2017-05-01 00:00:00

abstract：:Insects are able to effectively recognize parasitoid eggs or larvae and to eliminate them by formation of a hemocytic capsule. Although the cellular process is now well documented, the genetic aspects of recognition of foreignness and the encapsulation process are still poorly understood. Experiments using the isofema...

journal_title：Developmental and comparative immunology

authors： Carton Y,Boulétreau M

更新日期：1985-04-01 00:00:00

abstract：:ADP-ribosylation factors (Arfs) are small GTP-binding proteins that have an essential function in intracellular trafficking and organelle structure. To date, little information is available on the Arfs in the economically important giant freshwater prawn Macrobrachium rosenbergii and their relationship to viral infect...

journal_title：Developmental and comparative immunology

authors： Ding ZF,Ren J,Tan JM,Wang Z,Yin SW,Huang Y,Huang X,Wang W,Lan JF,Ren Q

更新日期：2015-01-01 00:00:00

abstract：:Lower vertebrates have been found to possess over 200 NACHT-domain encoding genes; but, to date, very little is known about their functional activity. This article describes the sequences and expression analysis of two zebrafish NACHT-containing proteins, namely NALPL1 and NALPL2. In addition, the functions of zebrafi...

journal_title：Developmental and comparative immunology

authors： Hu YW,Yu ZL,Xue NN,Nie P,Chang MX

更新日期：2014-10-01 00:00:00

abstract：:An alternative complement pathway-inhibiting protein (ACPIP), which inhibits the activation of the alternative complement pathway (ACP) of the human serum, was isolated from larval hemolymph of the silkworm, Bombyx mori, by using ammonium sulfate fractionation and column chromatographies to homogeneity. About 400micro...

journal_title：Developmental and comparative immunology

authors： Sekijima Y,Fujikura Y,Hiyama T,Maenaka T,Uda A

更新日期：2001-03-01 00:00:00

abstract：:There is increasing concern about the possible effect of pharmaceutical compounds may have on the fish immune system. Bath exposition of 17α-ethynylestradiol (EE2), a synthetic estrogen used in oral contraceptives, altered the immune response of the gilthead seabream (Sparus aurata L.), a marine hermaphrodite teleost....

journal_title：Developmental and comparative immunology

authors： Rodenas MC,Cabas I,Abellán E,Meseguer J,Mulero V,García-Ayala A

更新日期：2015-12-01 00:00:00

abstract：:Complement components C3 and C4 have been isolated from the serum of the nurse shark (Ginglymostoma cirratum) and of the channel catfish (Ictalurus punctatus). As in the higher vertebrates, the fish C4 proteins have three-chain structures while the C3 proteins have two-chain structures. All four proteins have intra-ch...

journal_title：Developmental and comparative immunology

authors： Dodds AW,Smith SL,Levine RP,Willis AC

更新日期：1998-03-01 00:00:00

abstract：:Thrombocytes express Toll-like receptors (TLRs) that detect bacterial or viral pathogens to signal the release of cytokines and mediators. We examined inflammatory responses when thrombocytes were exposed to four TLR ligands. Treatment of thrombocytes with TLR ligands demonstrates differential effects on gene expressi...

journal_title：Developmental and comparative immunology

authors： Ferdous F,Scott T

更新日期：2015-04-01 00:00:00

abstract：:The dog is both a valued veterinary species and a widely used translational model for sepsis research. However, relatively little work has been performed evaluating potential biomarkers present during canine infection. Triggering receptor expressed on myeloid cells-1 (TREM-1) has shown promise as a biomarker for infec...

journal_title：Developmental and comparative immunology

authors： Li J,Birkenheuer AJ,Marr HS,Levy MG,Yoder JA,Nordone SK

更新日期：2011-08-01 00:00:00