Abstract:
BACKGROUND:In Ireland, horses may be protected against equine influenza virus (EIV) as a result of natural exposure or vaccination. Current mandatory vaccination programmes are targeted at highly mobile horses. A correlation between antibody levels as measured by single radial haemolysis (SRH) and protective immunity against EIV has been established. OBJECTIVES:The objective of this study was to determine the susceptibility of selected populations of horses by quantifying their antibodies to EIV. METHODS:Blood samples were collected from Thoroughbred weanlings, yearlings, racehorses and broodmares, teaser stallions and non-Thoroughbred horses. Antibodies against EIV H3N8 and H7N7 were measured by SRH. RESULTS:The order of susceptibility to Equine Influenza (EI) in the populations examined in Ireland was as follows: Thoroughbred weanlings > teasers > non-Thoroughbred horses and ponies > Thoroughbred yearlings > Thoroughbred horses in training > Thoroughbred broodmares. The H3N8 antibody levels of the weanlings, yearlings, broodmares and horses in training were similar to their H7N7 antibody levels, suggesting that their antibodies were primarily vaccinal in origin. The teasers and non-Thoroughbreds had higher H3N8 antibody levels than H7N7 antibody levels, suggesting that the majority of seropositive horses in these populations had been exposed to H3N8 by natural infection. CONCLUSIONS:Weanlings, teasers and non-Thoroughbred horses were identified as most susceptible to EIV. The results suggest that it would be advisable that weanlings are vaccinated prior to attendance at public sales, that teaser stallions are vaccinated prior to each breeding season and that mandatory vaccination be implemented for participation in non-Thoroughbred events.
journal_name
Influenza Other Respir Virusesjournal_title
Influenza and other respiratory virusesauthors
Gildea S,Arkins S,Cullinane Adoi
10.1111/j.1750-2659.2010.00163.xsubject
Has Abstractpub_date
2010-11-01 00:00:00pages
363-72issue
6eissn
1750-2640issn
1750-2659journal_volume
4pub_type
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pub_type: 杂志文章,meta分析
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更新日期:2015-07-01 00:00:00
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pub_type: 杂志文章,随机对照试验
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pub_type: 杂志文章
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更新日期:2015-07-01 00:00:00
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