Abstract:
BACKGROUND:Respiratory protective devices are critical in protecting against infection in healthcare workers at high risk of novel 2019 coronavirus disease (COVID-19); however, recommendations are conflicting and epidemiological data on their relative effectiveness against COVID-19 are limited. PURPOSE:To compare medical masks to N95 respirators in preventing laboratory-confirmed viral infection and respiratory illness including coronavirus specifically in healthcare workers. DATA SOURCES:MEDLINE, Embase, and CENTRAL from January 1, 2014, to March 9, 2020. Update of published search conducted from January 1, 1990, to December 9, 2014. STUDY SELECTION:Randomized controlled trials (RCTs) comparing the protective effect of medical masks to N95 respirators in healthcare workers. DATA EXTRACTION:Reviewer pair independently screened, extracted data, and assessed risk of bias and the certainty of the evidence. DATA SYNTHESIS:Four RCTs were meta-analyzed adjusting for clustering. Compared with N95 respirators; the use of medical masks did not increase laboratory-confirmed viral (including coronaviruses) respiratory infection (OR 1.06; 95% CI 0.90-1.25; I2 = 0%; low certainty in the evidence) or clinical respiratory illness (OR 1.49; 95% CI: 0.98-2.28; I2 = 78%; very low certainty in the evidence). Only one trial evaluated coronaviruses separately and found no difference between the two groups (P = .49). LIMITATIONS:Indirectness and imprecision of available evidence. CONCLUSIONS:Low certainty evidence suggests that medical masks and N95 respirators offer similar protection against viral respiratory infection including coronavirus in healthcare workers during non-aerosol-generating care. Preservation of N95 respirators for high-risk, aerosol-generating procedures in this pandemic should be considered when in short supply.
journal_name
Influenza Other Respir Virusesjournal_title
Influenza and other respiratory virusesauthors
Bartoszko JJ,Farooqi MAM,Alhazzani W,Loeb Mdoi
10.1111/irv.12745subject
Has Abstractpub_date
2020-07-01 00:00:00pages
365-373issue
4eissn
1750-2640issn
1750-2659journal_volume
14pub_type
杂志文章,meta分析abstract:OBJECTIVES:Knowledge of the secondary attack rate (SAR) and serial interval (SI) of influenza is important for assessing the severity of seasonal epidemics of the virus. To date, such estimates have required extensive surveys of target populations. Here, we propose a method for estimating the intrafamily SAR and SI fro...
journal_title:Influenza and other respiratory viruses
pub_type: 杂志文章
doi:10.1111/irv.12321
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journal_title:Influenza and other respiratory viruses
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journal_title:Influenza and other respiratory viruses
pub_type: 杂志文章,评审
doi:10.1111/irv.12313
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journal_title:Influenza and other respiratory viruses
pub_type: 杂志文章
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更新日期:2010-09-01 00:00:00
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journal_title:Influenza and other respiratory viruses
pub_type: 杂志文章
doi:10.1111/irv.12732
更新日期:2020-07-01 00:00:00
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pub_type: 杂志文章,随机对照试验
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journal_title:Influenza and other respiratory viruses
pub_type: 杂志文章,评审
doi:10.1111/irv.12446
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abstract::A dramatic increase of influenza activity in Russia since week 3 of 2016 significantly differs from previous seasons in terms of the incidence of influenza and acute respiratory infection (ARI) and in number of lethal cases. We performed antigenic analysis of 108 and whole-genome sequencing of 77 influenza A(H1N1)pdm0...
journal_title:Influenza and other respiratory viruses
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doi:10.1111/irv.12389
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journal_title:Influenza and other respiratory viruses
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pub_type: 杂志文章
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journal_title:Influenza and other respiratory viruses
pub_type: 杂志文章
doi:10.1111/irv.12302
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journal_title:Influenza and other respiratory viruses
pub_type: 杂志文章
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journal_title:Influenza and other respiratory viruses
pub_type: 杂志文章,随机对照试验,评审
doi:10.1111/j.1750-2659.2008.00067.x
更新日期:2008-11-01 00:00:00
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pub_type: 杂志文章,随机对照试验
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更新日期:2013-11-01 00:00:00
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journal_title:Influenza and other respiratory viruses
pub_type: 杂志文章,meta分析
doi:10.1111/j.1750-2659.2009.00124.x
更新日期:2010-05-01 00:00:00
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pub_type: 杂志文章,评审
doi:10.1111/irv.12565
更新日期:2018-09-01 00:00:00
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journal_title:Influenza and other respiratory viruses
pub_type: 杂志文章
doi:10.1111/j.1750-2659.2009.00073.x
更新日期:2009-01-01 00:00:00
abstract:BACKGROUND:Pregnant women have an elevated risk of illness and hospitalisation from influenza. Pregnant women are recommended to be prioritised for influenza vaccination during any stage of pregnancy. The risk of seasonal influenza varies substantially throughout the year in temperate climates; however, there is limite...
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pub_type: 杂志文章,meta分析
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更新日期:2019-09-01 00:00:00
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pub_type: 杂志文章,评审
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pub_type: 杂志文章
doi:10.1111/j.1750-2659.2011.00256.x
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journal_title:Influenza and other respiratory viruses
pub_type: 杂志文章,评审
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pub_type: 杂志文章
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journal_title:Influenza and other respiratory viruses
pub_type: 杂志文章
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journal_title:Influenza and other respiratory viruses
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journal_title:Influenza and other respiratory viruses
pub_type: 杂志文章
doi:10.1111/j.1750-2659.2012.00398.x
更新日期:2013-05-01 00:00:00
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pub_type: 杂志文章
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