Clinical relevance of sperm DNA assessment: an update.

Abstract:

:For sperm DNA assessments to be widespread effective clinical tools, key objectives need to be urgently achieved. These include robust standardized methods, systems for training staff and ongoing quality control; and rigorous examination of the clinical outcomes. We discuss the significance of these objectives and conclude that, if achieved, the clinical utility of DNA damage assessment will be fully realized.

journal_name

Fertil Steril

journal_title

Fertility and sterility

authors

Barratt CL,De Jonge CJ

doi

10.1016/j.fertnstert.2010.07.1050

subject

Has Abstract

pub_date

2010-11-01 00:00:00

pages

1958-9

issue

6

eissn

0015-0282

issn

1556-5653

pii

S0015-0282(10)02156-4

journal_volume

94

pub_type

社论
  • Effect of obesity on the response to acute adrenocorticotropin stimulation in eumenorrheic women.

    abstract:OBJECTIVE:Alterations in adrenocortical biosynthesis, as measured by the steroid response to acute adrenocorticotropic hormone (ACTH) stimulation, have frequently been reported in female hyperandrogenism. These patients are also commonly obese, which may account for some of these abnormalities. The object of this study...

    journal_title:Fertility and sterility

    pub_type: 杂志文章

    doi:

    authors: Azziz R,Zacur HA,Parker CR Jr,Bradley EL Jr,Boots LR

    更新日期:1991-09-01 00:00:00

  • A direct effect of antiovulatory compounds on human testicular biosynthesis in vitro.

    abstract::Human testes, removed in treating patients for prostatic carcinoma, were used. Tissues were homogenized and incubated in vitro with labeled progesterone and 2 different antiovulatories, lynestrenol (17alpha-ethin yl-17beta-hydroxy-estr-4-one) and MK 665 (17alpha-chloroethinyl-19-nor-4 ,9(10)-androstadiene-17beta-ol-...

    journal_title:Fertility and sterility

    pub_type: 杂志文章

    doi:10.1016/s0015-0282(16)36309-9

    authors: Balatti JJ,Claret A,Rosner JM

    更新日期:1967-05-01 00:00:00

  • Menstrual endometrial cells from women with endometriosis demonstrate increased adherence to peritoneal cells and increased expression of CD44 splice variants.

    abstract:OBJECTIVE:We previously demonstrated that adherence of endometrial epithelial (EECs) and stromal cells (ESCs) to peritoneal mesothelial cells (PMCs) is partly regulated by ESC/EEC CD44 interactions with PMC associated hyaluronan. CD44, a transmembrane glycoprotein and major ligand for hyaluronan, has numerous splice va...

    journal_title:Fertility and sterility

    pub_type: 杂志文章

    doi:10.1016/j.fertnstert.2008.12.012

    authors: Griffith JS,Liu YG,Tekmal RR,Binkley PA,Holden AE,Schenken RS

    更新日期:2010-04-01 00:00:00

  • Induction of hypothalamic opioid activity with transdermal estradiol administration in postmenopausal women.

    abstract::The effects of estradiol (E2) administered by a transdermal system on the induction of hypothalamic opioid activity was examined in 18 postmenopausal women. Women were given 25, 50, 100, or 200 micrograms/d dosages of E2 for 28 days each. Naloxone at a dosage of 2 mg/h was infused intravenously for 4 hours, and serum ...

    journal_title:Fertility and sterility

    pub_type: 杂志文章

    doi:

    authors: D'Amico JF,Greendale GA,Lu JK,Judd HL

    更新日期:1991-04-01 00:00:00

  • Sperm chromatin structure assay parameters are not related to fertilization rates, embryo quality, and pregnancy rates in in vitro fertilization and intracytoplasmic sperm injection, but might be related to spontaneous abortion rates.

    abstract:OBJECTIVE:To investigate the relationship between sperm chromatin structure assay (SCSA) parameters, DNA fragmentation index (DFI) and high DNA stainability (HDS), and outcomes of IVF and intracytoplasmic sperm injection (ICSI). DESIGN:Retrospective review and prospective study. SETTING:Academic human reproduction la...

    journal_title:Fertility and sterility

    pub_type: 杂志文章,评审

    doi:10.1016/j.fertnstert.2007.06.018

    authors: Lin MH,Kuo-Kuang Lee R,Li SH,Lu CH,Sun FJ,Hwu YM

    更新日期:2008-08-01 00:00:00

  • In vitro fertilization patients support a single blastocyst transfer policy.

    abstract:OBJECTIVE:To determine whether patients support a mandatory single blastocyst transfer (mSBT) policy in IVF. DESIGN:Prospective survey study. SETTING:Academic hospital-based infertility center. PATIENT(S):Two hundred sixty-two female patients presenting for fresh or cryopreserved/thawed ET after IVF. INTERVENTION(S...

    journal_title:Fertility and sterility

    pub_type: 杂志文章

    doi:10.1016/j.fertnstert.2011.07.1140

    authors: Martini S,Van Voorhis BJ,Stegmann BJ,Sparks AE,Shochet T,Zimmerman MB,Ryan GL

    更新日期:2011-10-01 00:00:00

  • Effects of hormonal therapies and dietary soy phytoestrogens on vaginal cytology in surgically postmenopausal macaques.

    abstract:OBJECTIVE:To evaluate the effects of conjugated equine estrogens, medroxyprogesterone acetate (MPA), conjugated equine estrogens combined with MPA, tamoxifen, and soybean estrogens on vaginal cytology in surgically postmenopausal cynomolgus macaques (Macaca fascicularis). DESIGN:Randomized long-term experimental trial...

    journal_title:Fertility and sterility

    pub_type: 杂志文章

    doi:

    authors: Cline JM,Paschold JC,Anthony MS,Obasanjo IO,Adams MR

    更新日期:1996-05-01 00:00:00

  • Surgically induced ovulation in the polycystic ovary syndrome: wedge resection revisited in the age of laparoscopy.

    abstract:OBJECTIVE:To provide an up-to-date comprehensive review of published data on laparoscopic methods of ovulation induction in the polycystic ovary syndrome (PCOS). Areas to be considered include the historical background of these procedures, their outcomes as reported in the literature, and their potential adverse effect...

    journal_title:Fertility and sterility

    pub_type: 杂志文章,评审

    doi:10.1016/s0015-0282(16)57408-1

    authors: Donesky BW,Adashi EY

    更新日期:1995-03-01 00:00:00

  • Vitrification of the human embryo: a more efficient and safer in vitro fertilization treatment.

    abstract::Cryopreservation has become a central pillar in assisted reproduction, reflected in the exponential increase of "freeze all" cycles in the past few years. Vitrification makes it possible to cool and warm human eggs and embryos with far less cryo-damage than 'slow-freeze' and allows nearly intact survival of embryos wi...

    journal_title:Fertility and sterility

    pub_type: 杂志文章,评审

    doi:10.1016/j.fertnstert.2019.12.009

    authors: Nagy ZP,Shapiro D,Chang CC

    更新日期:2020-02-01 00:00:00

  • Common genetic variation in MTNR1B is associated with serum testosterone, glucose tolerance, and insulin secretion in polycystic ovary syndrome patients.

    abstract::Melatonin plays an important role in many aspects of the human reproductive process. Our results first strongly suggest that MTNR1B mediating some functions of melatonin contributes to the phenotypic expression of polycystic ovary syndrome, which provide a new insight into the role of MTNR1B gene in the pathophysiolog...

    journal_title:Fertility and sterility

    pub_type: 杂志文章

    doi:10.1016/j.fertnstert.2010.01.059

    authors: Wang L,Wang Y,Zhang X,Shi J,Wang M,Wei Z,Zhao A,Li B,Zhao X,Xing Q,He L

    更新日期:2010-11-01 00:00:00

  • Measurement of the ovarian follicle by ultrasound in ovulation induction.

    abstract::Ultrasonic monitoring of ovarian follicles and estimation of serum estradiol were carried out in 12 patients with clomiphene therapy, in 5 patients with gonadotropin therapy, and in 7 normal controls. The average diameter of preovulatory follicles in normal controls was 12,8 mm; in ovulation induction groups it was 2 ...

    journal_title:Fertility and sterility

    pub_type: 杂志文章

    doi:10.1016/s0015-0282(16)44055-0

    authors: Ylöstalo P,Rönnberg L,Jouppila P

    更新日期:1979-06-01 00:00:00

  • Funding and public reporting strategies for reducing multiple pregnancy from fertility treatments.

    abstract::The health of children born through assisted reproductive technologies (ART) is particularly vulnerable to policy decisions and market forces that play out before they are even conceived. ART treatment is costly, and public and third-party funding varies significantly between and within countries, leading to considera...

    journal_title:Fertility and sterility

    pub_type: 杂志文章,评审

    doi:10.1016/j.fertnstert.2020.08.1405

    authors: Chambers GM,Keller E,Choi S,Khalaf Y,Crawford S,Botha W,Ledger W

    更新日期:2020-10-01 00:00:00

  • Serum levels of soluble vascular cell adhesion molecule-1, tumor necrosis factor-alpha, and interleukin-6 in in vitro fertilization cycles.

    abstract:OBJECTIVE:To assess whether gonadotropin-induced changes in E(2) alter serum levels of soluble vascular cell adhesion molecule-1 (sVCAM-1) and proinflammatory cytokines. DESIGN:Prospective collection of serum in patients undergoing IVF. SETTING:University hospital. PATIENT(S):Twenty-four infertile women. INTERVENTI...

    journal_title:Fertility and sterility

    pub_type: 杂志文章

    doi:10.1016/j.fertnstert.2008.04.039

    authors: Souter I,Huang A,Martinez-Maza O,Breen EC,Decherney AH,Chaudhuri G,Nathan L

    更新日期:2009-05-01 00:00:00

  • Treatment of clomiphene citrate-resistant polycystic ovarian syndrome with pure follicle-stimulating hormone or human menopausal gonadotropin.

    abstract::Two hundred ten treatment cycles of follicle-stimulating hormone (FSH) or human menopausal gonadotropin (hMG) were completed in 49 patients with clomiphene citrate-resistant polycystic ovarian syndrome. The results from 68 cycles of daily intramuscular (IM) FSH and 41 cycles of IM hMG were compared. The ovulation rate...

    journal_title:Fertility and sterility

    pub_type: 杂志文章

    doi:10.1016/s0015-0282(16)53511-0

    authors: McFaul PB,Traub AI,Thompson W

    更新日期:1990-05-01 00:00:00

  • The heparin-glutathione test: an alternative to the hypo-osmotic swelling test to select viable sperm for intracytoplasmic sperm injection.

    abstract:OBJECTIVE:To evaluate the heparin-glutathione test (HEGLUT) for the selection of viable sperm for intracytoplasmic sperm injection (ICSI). DESIGN:A prospective study. SETTING:Department of Pediatrics, Obstetrics and Gynecology, University of Valencia and Instituto Valenciano de Infertilidad. PATIENT(S):Semen samples...

    journal_title:Fertility and sterility

    pub_type: 杂志文章

    doi:10.1016/s0015-0282(98)00334-3

    authors: Vendrell FJ,Rubio C,Tarín JJ

    更新日期:1998-12-01 00:00:00

  • The use of biosynthetic human growth hormone to augment ovulation induction with buserelin acetate/human menopausal gonadotropin in women with a poor ovarian response.

    abstract::The present study has demonstrated the usefulness of GH in augmenting buserelin acetate/hMG to stimulate the rate of growth of follicles in women regarded as poor responders. The PR achieved was extremely encouraging in a group of patients whose prognosis was otherwise poor. Further studies are required to confirm the...

    journal_title:Fertility and sterility

    pub_type: 临床试验,杂志文章

    doi:10.1016/s0015-0282(16)54084-9

    authors: Ibrahim ZH,Matson PL,Buck P,Lieberman BA

    更新日期:1991-01-01 00:00:00

  • Comparison of low-dose human menopausal gonadotropin and micronized 17beta-estradiol supplementation in in vitro maturation cycles with thin endometrial lining.

    abstract:OBJECTIVE:A challenge of in vitro maturation (IVM) treatment in some women is insufficient development of the endometrium prior to embryo transfer. DESIGN:Retrospective study. SETTING:McGill Reproductive Center, Montreal, Canada. PATIENT(S):Women with endometrial thickness <6 mm on days 6-10 ultrasound (US) scan of ...

    journal_title:Fertility and sterility

    pub_type: 杂志文章

    doi:10.1016/j.fertnstert.2008.07.1750

    authors: Elizur SE,Son WY,Yap R,Gidoni Y,Levin D,Demirtas E,Tan SL

    更新日期:2009-09-01 00:00:00

  • Who's keeping count? The need for regulation is a relative matter.

    abstract::It is important to have an accurate model for calculating limits to sperm donation so as to avoid inadvertent half-sibling mating and help protect the rights and welfare of the donor- inseminated child. The most highly developed model to date cannot be used as there is inadequate regulation of donor insemination among...

    journal_title:Fertility and sterility

    pub_type: 杂志文章

    doi:10.1016/j.fertnstert.2009.01.099

    authors: Sawyer N

    更新日期:2009-12-01 00:00:00

  • Distribution of type IV collagen subtypes in human testes and their association with spermatogenesis.

    abstract:OBJECTIVE:To evaluate the expression of type IV collagen [alpha1(IV) to alpha6(IV)] in testes and the association with spermatogenesis. DESIGN:Retrospective immunohistochemical study. SETTING:Division of Urology, Department of Organs Therapeutics, Faculty of Medicine, in a university hospital. PATIENT(S):Testicular ...

    journal_title:Fertility and sterility

    pub_type: 杂志文章

    doi:10.1016/s0015-0282(03)00775-1

    authors: Dobashi M,Fujisawa M,Naito I,Yamazaki T,Okada H,Kamidono S

    更新日期:2003-09-01 00:00:00

  • Can growth hormone increase, after clonidine administration, predict the dose of human menopausal hormone needed for induction of ovulation?

    abstract::Recent observations claimed that growth hormone (GH) administration increased the sensitivity of the ovary to gonadotropin stimulation. These findings prompted us to assess whether ovarian response to human menopausal gonadotropin (hMG) is correlated to GH reserve. Before hMG administration, 25 patients were tested fo...

    journal_title:Fertility and sterility

    pub_type: 杂志文章

    doi:10.1016/s0015-0282(16)53336-6

    authors: Menashe Y,Lunenfeld B,Pariente C,Frenkel Y,Mashiach S

    更新日期:1990-03-01 00:00:00

  • True hermaphroditism presenting as bilateral gynecomastia in an adolescent phenotypic male.

    abstract:OBJECTIVE:To report a rare case of true hermaphroditism presenting in adolescence as bilateral gynecomastia in a phenotypic male. DESIGN:Case report. SETTING:Academic medical center. PATIENT(S):A 19-year-old phenotypic male who presented with pronounced bilateral gynecomastia and was ultimately diagnosed with true h...

    journal_title:Fertility and sterility

    pub_type: 杂志文章

    doi:10.1016/j.fertnstert.2004.09.036

    authors: Ouhilal S,Turco J,Nangia A,Stotland M,Manganiello PD

    更新日期:2005-04-01 00:00:00

  • A comparison study of a novel stimulation protocol and the conventional low dose step-up and step-down regimens in patients with polycystic ovary syndrome undergoing in vitro fertilization.

    abstract:OBJECTIVE:To compare the efficacy of a sequential step-up/step-down protocol with the conventional low dose step-up and the step-down regimens in patients with polycystic ovary syndrome (PCOS) undergoing IVF. DESIGN:Prospective randomized study. SETTING:Private fertility clinic. PATIENT(S):Two hundred twenty-five, 3...

    journal_title:Fertility and sterility

    pub_type: 杂志文章,随机对照试验

    doi:10.1016/j.fertnstert.2007.06.080

    authors: Koundouros SN

    更新日期:2008-09-01 00:00:00

  • Use of gonadotropin-releasing hormone agonist trigger during in vitro fertilization is associated with similar endocrine profiles and oocyte measures in women with and without polycystic ovary syndrome.

    abstract:OBJECTIVE:To compare endocrine profiles and IVF outcomes after using GnRH agonists (GnRHa) to trigger final oocyte maturation in women with polycystic ovary syndrome (PCOS) with other hyper-responders. DESIGN:Retrospective cohort study. SETTING:Academic center. PATIENT(S):Forty women with PCOS and 74 hyper-responder...

    journal_title:Fertility and sterility

    pub_type: 杂志文章

    doi:10.1016/j.fertnstert.2014.09.042

    authors: O'Neill KE,Senapati S,Dokras A

    更新日期:2015-01-01 00:00:00

  • Donation of fertilized uterine ova to infertile women.

    abstract::Nonsurgical recovery of a preimplantation conceptus from the uterus of a fertile donor woman with transfer to an infertile recipient woman and subsequent pregnancy has been described previously. In this report, we describe the performance of 56 nonsurgical uterine lavages, recovery of 23 ova, and transfer of 17 ova wi...

    journal_title:Fertility and sterility

    pub_type: 杂志文章

    doi:

    authors: Formigli L,Formigli G,Roccio C

    更新日期:1987-01-01 00:00:00

  • Recommended practices for the management of embryology, andrology, and endocrinology laboratories: a committee opinion.

    abstract::This document provides a general overview for physicians of the qualities and conditions necessary for good management practices within the endocrinology, andrology, and embryology laboratories in the United States. It is intended as an addendum to previously published guidelines that further detail these responsibili...

    journal_title:Fertility and sterility

    pub_type: 杂志文章,实务指引,评审

    doi:10.1016/j.fertnstert.2014.06.036

    authors: Practice Committee of the American Society for Reproductive Medicine.,Practice Committee of the Society for Assisted Reproductive Technology.,Practice Committee of the Society of Reproductive Biologists and Technologists.

    更新日期:2014-10-01 00:00:00

  • The prostaglandin inhibitor effect of antiinflammatory drugs in the therapy of male infertility.

    abstract::The effects of various doses of indomethacin and ketoprofen as compared with placebo were examined in 100 oligospermic patients who participated in this study. It was found that the treatment increased sperm count, sperm motility, and fertilizing capacity. The radioimmunoassay examination showed an increase in plasma ...

    journal_title:Fertility and sterility

    pub_type: 临床试验,杂志文章

    doi:10.1016/s0015-0282(16)48081-7

    authors: Barkay J,Harpaz-Kerpel S,Ben-Ezra S,Gordon S,Zuckerman H

    更新日期:1984-09-01 00:00:00

  • Apoptosis and expression of Bcl-2 and Bax in eutopic endometrium from women with endometriosis.

    abstract:OBJECTIVE:To evaluate and compare spontaneous apoptosis and Bcl-2 and Bax expression in eutopic endometrium from women with and without endometriosis. DESIGN:Apoptosis and Bcl-2 and Bax expression were examined in eutopic endometrium from women with and without endometriosis. SETTING:Instituto de Biología y Medicina ...

    journal_title:Fertility and sterility

    pub_type: 杂志文章

    doi:10.1016/s0015-0282(00)01522-3

    authors: Meresman GF,Vighi S,Buquet RA,Contreras-Ortiz O,Tesone M,Rumi LS

    更新日期:2000-10-01 00:00:00

  • Coordination of early antral follicles by luteal estradiol administration provides a basis for alternative controlled ovarian hyperstimulation regimens.

    abstract:OBJECTIVE:To investigate whether luteal E(2) administration reduces size discrepancies of early antral follicles. DESIGN:Prospective, crossover study. SETTING:ART unit, Clamart, France. PATIENT(S):Sixty women and 120 cycles. INTERVENTION(S):On cycle day 3 (baseline day 3), all women underwent measurements of early ...

    journal_title:Fertility and sterility

    pub_type: 临床试验,杂志文章

    doi:10.1016/s0015-0282(02)04574-0

    authors: Fanchin R,Cunha-Filho JS,Schonäuer LM,Kadoch IJ,Cohen-Bacri P,Frydman R

    更新日期:2003-02-01 00:00:00

  • Use of insulin-sensitizing agents in the treatment of polycystic ovary syndrome.

    abstract::The role of insulin sensitizing agents is discussed at length in this Committee Opinion. ...

    journal_title:Fertility and sterility

    pub_type: 杂志文章,评审

    doi:10.1016/j.fertnstert.2008.08.004

    authors: Practice Committee of American Society for Reproductive Medicine.

    更新日期:2008-11-01 00:00:00

  • Intercycle variability of day 3 follicle-stimulating hormone levels and its effect on stimulation quality in in vitro fertilization.

    abstract::Prior studies have demonstrated that gonadotropin stimulation quality and pregnancy rates are better in in vitro fertilization (IVF) patients with low basal cycle day 3 follicle-stimulating hormone (FSH) levels. The records of 81 patients who had undergone three or more IVF attempts during a 2-year period were studied...

    journal_title:Fertility and sterility

    pub_type: 杂志文章

    doi:10.1016/s0015-0282(16)53707-8

    authors: Scott RT Jr,Hofmann GE,Oehninger S,Muasher SJ

    更新日期:1990-08-01 00:00:00