Abstract：
:Environmental change has altered the phenology, morphological traits and population dynamics of many species. However, the links underlying these joint responses remain largely unknown owing to a paucity of long-term data and the lack of an appropriate analytical framework. Here we investigate the link between phenotypic and demographic responses to environmental change using a new methodology and a long-term (1976-2008) data set from a hibernating mammal (the yellow-bellied marmot) inhabiting a dynamic subalpine habitat. We demonstrate how earlier emergence from hibernation and earlier weaning of young has led to a longer growing season and larger body masses before hibernation. The resulting shift in both the phenotype and the relationship between phenotype and fitness components led to a decline in adult mortality, which in turn triggered an abrupt increase in population size in recent years. Direct and trait-mediated effects of environmental change made comparable contributions to the observed marked increase in population growth. Our results help explain how a shift in phenology can cause simultaneous phenotypic and demographic changes, and highlight the need for a theory integrating ecological and evolutionary dynamics in stochastic environments.
journal_name
Naturejournal_title
Natureauthors
Ozgul A,Childs DZ,Oli MK,Armitage KB,Blumstein DT,Olson LE,Tuljapurkar S,Coulson Tdoi
10.1038/nature09210subject
Has Abstractpub_date
2010-07-22 00:00:00pages
482-5issue
7305eissn
0028-0836issn
1476-4687pii
nature09210journal_volume
466pub_type
杂志文章相关文献
NATURE文献大全abstract：:In this Letter, a citation to 'Fig. 1e' has been corrected to 'Fig. 1d' in the sentence starting "By contrast, the anti-tumour response…". This has been corrected online. ...
journal_title：Nature
pub_type： 已发布勘误
doi：10.1038/s41586-019-1046-1
更新日期：2019-04-01 00:00:00
abstract：:This is an exciting time for scientific discovery that aims to reduce the frequency and impact of neurological, mental health and substance-use disorders. As it became increasingly clear that low- and middle-income countries have a disproportionate share of these disorders, and that many of the problems are best addre...
journal_title：Nature
pub_type： 杂志文章
doi：10.1038/nature16028
更新日期：2015-11-19 00:00:00
abstract：:Muscle force is generated by myosin crossbridges interacting with actin. As estimated from stiffness and equatorial X-ray diffraction of muscle and muscle fibres, most myosin crossbridges are attached to actin during isometric contraction, but a much smaller fraction is bound stereospecifically. To determine the fract...
journal_title：Nature
pub_type： 杂志文章
doi：10.1038/40651
更新日期：1997-07-10 00:00:00
abstract：:Susceptibility to some human diseases is linked, albeit weakly, to major transplantation antigens (HLA) encoded by the major histocompatibility gene complex (MHC). Here we have studied MHC/disease association in inbred strains of mice after intracerebral (i.c.) injection of lymphocytic choriomeningitis virus (LCMV). T...
journal_title：Nature
pub_type： 杂志文章
doi：10.1038/316814a0
更新日期：1985-08-29 00:00:00
abstract：:Dehydration or desiccation is one of the most frequent and severe challenges to living cells. The bacterium Deinococcus radiodurans is the best known extremophile among the few organisms that can survive extremely high exposures to desiccation and ionizing radiation, which shatter its genome into hundreds of short DNA...
journal_title：Nature
pub_type： 杂志文章
doi：10.1038/nature05160
更新日期：2006-10-05 00:00:00
abstract：: ...
journal_title：Nature
pub_type： 新闻
doi：10.1038/d41586-019-00121-0
更新日期：2019-01-01 00:00:00
abstract：:The dehydration of subducting oceanic crust and upper mantle has been inferred both to promote the partial melting leading to arc magmatism and to induce intraslab intermediate-depth earthquakes, at depths of 50-300 km. Yet there is still no consensus about how slab hydration occurs or where and how much chemically bo...
journal_title：Nature
pub_type： 杂志文章
doi：10.1038/nature01961
更新日期：2003-09-25 00:00:00
abstract：:Self-propagating beta-sheet-rich protein aggregates are implicated in a wide range of protein-misfolding phenomena, including amyloid diseases and prion-based inheritance. Two properties have emerged as common features of amyloids. Amyloid formation is ubiquitous: many unrelated proteins form such aggregates and even ...
journal_title：Nature
pub_type： 杂志文章
doi：10.1038/nature01894
更新日期：2003-08-21 00:00:00
abstract：:Aquifex aeolicus was one of the earliest diverging, and is one of the most thermophilic, bacteria known. It can grow on hydrogen, oxygen, carbon dioxide, and mineral salts. The complex metabolic machinery needed for A. aeolicus to function as a chemolithoautotroph (an organism which uses an inorganic carbon source for...
journal_title：Nature
pub_type： 杂志文章
doi：10.1038/32831
更新日期：1998-03-26 00:00:00
abstract：:Endocytosis of the major histocompatibility complex (MHC)-encoded class I and class II molecules has been the subject of recent investigations. Class I molecules, which are key elements in T cell-mediated cytotoxicity, are differentially endocytosed by different cell types. Fibroblasts internalize their class I molecu...
journal_title：Nature
pub_type： 杂志文章
doi：10.1038/328724a0
更新日期：1987-08-20 00:00:00
abstract：:The neuronal structure and connectivity underlying receptive field organisation of cells in the cat visual cortex have been investigated. Intracellular recordings were made using a micropipette filled with a histochemical marker, which was injected into the cells after their receptive fields had been characterised. Th...
journal_title：Nature
pub_type： 杂志文章
doi：10.1038/280120a0
更新日期：1979-07-12 00:00:00
abstract：:We are in the enviable position of having two distinct drafts of the human genome sequence. Although gaps, errors, redundancy and incomplete annotation mean that individually each falls short of the ideal, many of these problems can be assessed by comparison. Here we present some comparative analyses of these drafts. ...
journal_title：Nature
pub_type： 杂志文章
doi：10.1038/35057055
更新日期：2001-02-15 00:00:00
abstract：:Homoiotherms, for example mammals, regulate their body temperature with physiological responses such as a change of metabolic rate and sweating. In contrast, the body temperature of poikilotherms, for example Drosophila, is the result of heat exchange with the surrounding environment as a result of the large ratio of ...
journal_title：Nature
pub_type： 杂志文章
doi：10.1038/nature07090
更新日期：2008-08-07 00:00:00
abstract：: ...
journal_title：Nature
pub_type： 评论,新闻
doi：10.1038/d41586-018-07165-8
更新日期：2018-11-01 00:00:00
abstract：:The antigen receptors on mature B lymphocytes are membrane-bound immunoglobulins of the IgM and IgD classes whose cross-linking by polyvalent antigens results in B-cell proliferation and differentiation. How these membrane-bound immunoglobulin chains, which lack a cytoplasmic tail, generate a cell activation signal is...
journal_title：Nature
pub_type： 杂志文章
doi：10.1038/343760a0
更新日期：1990-02-22 00:00:00
abstract：:The distribution of fitness effects of protein mutations is still unknown. Of particular interest is whether accumulating deleterious mutations interact, and how the resulting epistatic effects shape the protein's fitness landscape. Here we apply a model system in which bacterial fitness correlates with the enzymatic ...
journal_title：Nature
pub_type： 杂志文章
doi：10.1038/nature05385
更新日期：2006-12-14 00:00:00
abstract：:The autosomal dominant hyper-IgE syndrome (HIES, 'Job's syndrome') is characterized by recurrent and often severe pulmonary infections, pneumatoceles, eczema, staphylococcal abscesses, mucocutaneous candidiasis, and abnormalities of bone and connective tissue. Mutations presumed to underlie HIES have recently been ide...
journal_title：Nature
pub_type： 杂志文章
doi：10.1038/nature06764
更新日期：2008-04-10 00:00:00
abstract：:Neurotransmitter release is initiated by influx of Ca2+ through voltage-gated Ca2+ channels, within 200 microseconds of the action potential arriving at the synaptic terminal, as the Ca2+ concentration increases from 100 nM to > 200 microM. Exocytosis requires high Ca2+ concentration, with a threshold of 20-50 microM ...
journal_title：Nature
pub_type： 杂志文章
doi：10.1038/379451a0
更新日期：1996-02-01 00:00:00
abstract：:Hypermethylation of the promoters of tumour suppressor genes represses transcription of these genes, conferring growth advantages to cancer cells. How these changes arise is poorly understood. Here we show that the activity of oxygen-dependent ten-eleven translocation (TET) enzymes is reduced by tumour hypoxia in huma...
journal_title：Nature
pub_type： 杂志文章
doi：10.1038/nature19081
更新日期：2016-09-01 00:00:00
abstract：:The genes for the T-cell receptor, like the immunoglobulin genes, are rearranged as DNA. The mechanism of this rearrangement is not clear; unequal crossover between chromosomes and the looping-out and excision of the excess DNA have both been suggested. We isolated small polydisperse circular (spc) DNAs from mouse thy...
journal_title：Nature
pub_type： 杂志文章
doi：10.1038/327242a0
更新日期：1987-05-21 00:00:00
abstract：:Mammalian circadian clocks consist of complex integrated feedback loops that cannot be elucidated without comprehensive measurement of system dynamics and determination of network structures. To dissect such a complicated system, we took a systems-biological approach based on genomic, molecular and cell biological tec...
journal_title：Nature
pub_type： 杂志文章
doi：10.1038/nature00906
更新日期：2002-08-01 00:00:00
abstract：:The editing of RNA in trypanosomatid mitochondria involves the insertion and occasional deletion of uridine residues within coding regions of maxicircle messenger RNA transcripts. The extent to which the transcripts of homologous genes undergo editing differs in different species. In some, entire genes are edited (pan...
journal_title：Nature
pub_type： 杂志文章
doi：10.1038/368345a0
更新日期：1994-03-24 00:00:00
abstract：:Nonrandom chromosome rearrangements, observed in a variety of human and animal tumours, are associated in some cases with enhanced expression or deregulation of cellular oncogenes. Recently, it was shown that normal, diploid rodent cells are neoplastically transformed following transfection with two cooperating oncoge...
journal_title：Nature
pub_type： 杂志文章
doi：10.1038/316636a0
更新日期：1985-08-15 00:00:00
abstract：:Copper, zinc superoxide dismutase (SOD) catalyses the very rapid two-step dismutation of the toxic superoxide radical (O-2) to molecular oxygen and hydrogen peroxide through the alternate reduction and oxidation of the active-site copper. We report here that after refitting and further refinement of the previous 2 A s...
journal_title：Nature
pub_type： 杂志文章
doi：10.1038/306284a0
更新日期：1983-11-17 00:00:00
abstract：:Cells are organized on length scales ranging from ångström to micrometres. However, the mechanisms by which ångström-scale molecular properties are translated to micrometre-scale macroscopic properties are not well understood. Here we show that interactions between diverse synthetic, multivalent macromolecules (includ...
journal_title：Nature
pub_type： 杂志文章
doi：10.1038/nature10879
更新日期：2012-03-07 00:00:00
abstract：:The Altai region of Siberia was inhabited for parts of the Pleistocene by at least two groups of archaic hominins-Denisovans and Neanderthals. Denisova Cave, uniquely, contains stratified deposits that preserve skeletal and genetic evidence of both hominins, artefacts made from stone and other materials, and a range o...
journal_title：Nature
pub_type： 历史文章,杂志文章
doi：10.1038/s41586-018-0843-2
更新日期：2019-01-01 00:00:00
abstract：:The T-cell receptor has been studied intensely over the past 10 years in an effort to understand the molecular basis for major histocompatibility complex (MHC) restricted antigen recognition. The use of anti-receptor monoclonal antibodies to isolate and characterize the receptor from human and murine T-cell clones has...
journal_title：Nature
pub_type： 杂志文章
doi：10.1038/312771a0
更新日期：1984-12-20 00:00:00
abstract：:Human behaviour is thought to spread through face-to-face social networks, but it is difficult to identify social influence effects in observational studies, and it is unknown whether online social networks operate in the same way. Here we report results from a randomized controlled trial of political mobilization mes...
journal_title：Nature
pub_type： 杂志文章,随机对照试验
doi：10.1038/nature11421
更新日期：2012-09-13 00:00:00
abstract：:The alpha-like and beta-like globin genes have provided a paradigm for the study of molecular evolution and regulation of multigene families in eukaryotes. The human alpha-globin gene cluster, which is on chromosome 16 (ref. 1), consists of six genes arranged in the order 5'-zeta(embryonic)-psi zeta-psi alpha 2-psi al...
journal_title：Nature
pub_type： 杂志文章
doi：10.1038/321785a0
更新日期：1986-06-19 00:00:00
abstract：:Behavioural studies and field observations demonstrate that echolocating bats simultaneously perceive range, direction and shape of multiple objects in the environment as acoustic images derived from echoes. Cortical echo delay-tuned neurons contribute to the perception of object range, because focal inactivation of t...
journal_title：Nature
pub_type： 杂志文章
doi：10.1038/364620a0
更新日期：1993-08-12 00:00:00
