Abstract：
INTRODUCTION:Issues pertaining to the effective elimination of bacterial biofilm and disruption of biofilm structure still remains in endodontic disinfection. Nanoparticulates such as chitosan (CS-np) and zinc oxide (ZnO-np) are known to possess significant antibacterial properties. This study aimed to test (1) the efficacy of CS-np and ZnO-np in disinfecting and disrupting biofilm bacteria and (2) the long-term efficacy of these nanoparticulates following aging. METHODS:Enterococcus faecalis (ATCC & OG1RF) in planktonic and biofilm forms were treated with different concentrations of CS-np and ZnO-np. The treated bacteria were quantified by using microbiologic methods. The biofilm viability and structure after nanoparticulate treatment were assessed by using confocal laser scanning microscopy. The effect of aging by using sterile saliva and phosphate-buffered saline on the antibacterial properties of the nanoparticulates was also determined. RESULTS:The rate of bacterial killing by the nanoparticulates depended on the concentration and time of interaction. Total elimination of planktonic bacteria was observed in contrast to the biofilm bacteria, which survived even after 72 hours. The confocal microscopy images showed predominantly dead bacterial cells and significant reduction in the thickness of biofilm (P < .01) after nanoparticulate treatment in both groups. Both CS-np and ZnO-np were found to retain their antibacterial properties after aging for 90 days. CONCLUSIONS:The present study highlighted the efficacy of the nanoparticulates to reduce biofilm bacteria, disrupt biofilm structure, and retain the antibacterial property even after aging. CS-np and ZnO-np present a potential approach in biofilm disinfection.
journal_name
J Endodjournal_title
Journal of endodonticsauthors
Shrestha A,Shi Z,Neoh KG,Kishen Adoi
10.1016/j.joen.2010.02.008subject
Has Abstractpub_date
2010-06-01 00:00:00pages
1030-5issue
6eissn
0099-2399issn
1878-3554pii
S0099-2399(10)00134-2journal_volume
36pub_type
杂志文章abstract：INTRODUCTION:The anatomy of the maxillary C-shaped molar has been the subject of several case reports although no true prevalence research has ever been conducted. The aim of this observational study was to evaluate and characterize the incidence of these morphologies using cone-beam computed tomographic (CBCT) technol...
journal_title：Journal of endodontics
pub_type： 杂志文章
doi：10.1016/j.joen.2015.12.013
更新日期：2016-03-01 00:00:00
abstract：INTRODUCTION:Various factors may influence intracanal calcification in teeth treated with regenerative endodontic procedures. Bioactive materials, including ProRoot MTA (MTA; Dentsply Tulsa Dental Specialties, Memphis, TN) and Biodentine (BD; Septodont, Saint-Maur-des-Fossés, France), have been widely used as a coronal...
journal_title：Journal of endodontics
pub_type： 杂志文章
doi：10.1016/j.joen.2019.03.011
更新日期：2019-06-01 00:00:00
abstract：INTRODUCTION:We aimed to compare the antimicrobial efficacy of chlorhexidine (CHX) and sodium hypochlorite (NaOCl), 2 irrigants routinely used in root canal therapy of permanent teeth. METHODS:Electronic databases, including PubMed, EMBASE, Web of Science, and Cochrane Library, were searched for randomized controlled ...
journal_title：Journal of endodontics
pub_type： 杂志文章,meta分析
doi：10.1016/j.joen.2020.05.002
更新日期：2020-08-01 00:00:00
abstract：INTRODUCTION:Resin-based dental materials contain various diluent monomers that can interfere with vascular function by causing vasodilation. In this study, we evaluated the vasoactive potential of hydroxyethyl methacrylate (HEMA) and triethylene glycol dimethacrylate (TEGDMA) and the possible mechanism of their vascul...
journal_title：Journal of endodontics
pub_type： 杂志文章
doi：10.1016/j.joen.2010.11.038
更新日期：2011-03-01 00:00:00
abstract：INTRODUCTION:Teeth undergoing initial endodontic therapy have a very high survival rate. Some teeth that continue to show signs of pathosis after the initial therapy will require nonsurgical (orthograde) retreatment. Outcome assessment of endodontic retreatment is crucial for appropriate case selection and treatment pl...
journal_title：Journal of endodontics
pub_type： 杂志文章
doi：10.1016/j.joen.2010.02.009
更新日期：2010-05-01 00:00:00
abstract：:A case study is presented that described an acute flare-up of a tooth following a vital bleaching procedure. The case illustrates (a) the importance of assessing the pulpal and periradicular status of a tooth prior to any vital bleaching procedure; and (b) the alteration of the local adaptation syndrome by the bleachi...
journal_title：Journal of endodontics
pub_type： 杂志文章
doi：10.1016/S0099-2399(06)80488-7
更新日期：1992-07-01 00:00:00
abstract：INTRODUCTION:A major complication after endodontic treatment is persistent pain on biting or chewing. Although unsuccessful endodontic treatment can account for such pain, pain to chewing and biting can also be a result of an unsupported or propagated crown fracture. Crown fractures that extend apically result in deter...
journal_title：Journal of endodontics
pub_type： 杂志文章
doi：10.1016/j.joen.2014.06.021
更新日期：2015-01-01 00:00:00
abstract：INTRODUCTION:Warm vertically compacted gutta-percha obturation techniques use root canal sealers that are heated during the obturation. This study aims at investigating the suitability of selected sealers with warm gutta-percha obturation techniques. METHODS:The composition of an experimental sealer (Septodont; Saint ...
journal_title：Journal of endodontics
pub_type： 杂志文章
doi：10.1016/j.joen.2014.06.007
更新日期：2015-01-01 00:00:00
abstract：:The purpose of this study was to assess the push-out bond strength and coronal microleakage of the Epiphany (Pentron Clinical Technologies, Wallingford, CT) + Resilon (Resilon Research LLC, Madison, CT) obturation system with respect to different photoactivation methods used. Roots of human maxillary central incisors ...
journal_title：Journal of endodontics
pub_type： 杂志文章
doi：10.1016/j.joen.2007.07.028
更新日期：2007-12-01 00:00:00
abstract：INTRODUCTION:Complementary methods of anatomic diagnosis, including cone-beam computed tomographic (CBCT) imaging, may be useful in the diagnosis of mesiobuccal (MB) canals of maxillary molars. METHODS:Thirty-five maxillary first molars were subjected to ex vivo analysis and 4 CBCT protocols: i-CAT Classic (Imaging Sc...
journal_title：Journal of endodontics
pub_type： 杂志文章
doi：10.1016/j.joen.2016.12.011
更新日期：2017-05-01 00:00:00
abstract：INTRODUCTION:The occurrence of multiple injuries of the same tooth is extremely rare. This case report describes the treatment in a midroot and complicated crown-root-fractured permanent incisor that remained untreated for 4 years after the accident. METHODS:The tooth was treated by delayed partial pulpotomy using cal...
journal_title：Journal of endodontics
pub_type： 杂志文章
doi：10.1016/j.joen.2010.03.036
更新日期：2010-07-01 00:00:00
abstract：:The choice of one-visit versus two-visit root canal therapy for necrotic teeth with apical periodontitis is a source of current debate. The primary objective of this randomized controlled clinical trial was to compare radiographic evidence of periapical healing after root canal therapy completed in one visit or two vi...
journal_title：Journal of endodontics
pub_type： 杂志文章,随机对照试验
doi：10.1016/j.joen.2007.12.015
更新日期：2008-03-01 00:00:00
abstract：:A technique using K files with modified tips has been developed for the penetration of constricted canals. The tip of a #10 K file was sliced diagonally to make it thinner. Because this modified K file has an especially fine tip and an appropriate stiffness, it followed constricted or sharply curved canals well and ha...
journal_title：Journal of endodontics
pub_type： 杂志文章
doi：10.1016/S0099-2399(97)80190-2
更新日期：1997-06-01 00:00:00
abstract：:Ninety-six human molars were accessed. After flattening of the occlusal surface and removal of the apical two-thirds of the roots, the remaining canal space was instrumented by conventional methods. The teeth were divided into six groups of 15 teeth with three positive and three negative controls. The six experimental...
journal_title：Journal of endodontics
pub_type： 杂志文章
doi：10.1016/S0099-2399(06)80078-6
更新日期：1994-12-01 00:00:00
abstract：:Plasminogen activator converts plasminogen to plasmin, and plasmin activates the latent matrix metalloproteinases. Tissue plasminogen activator (t-PA) is one of the important proteolysis factors present in human inflamed tissues. However, few studies reported on the mechanisms of tissue destruction via a t-PA proteoly...
journal_title：Journal of endodontics
pub_type： 杂志文章
doi：10.1097/00004770-200302000-00007
更新日期：2003-02-01 00:00:00
abstract：INTRODUCTION:The purpose of this study was to examine the size, volume, and other parameters of preoperative periapical lesions measured from cone-beam computed tomographic (CBCT) images as potential prognostic factors in endodontic microsurgery. METHODS:A clinical database was searched for patients who had received e...
journal_title：Journal of endodontics
pub_type： 杂志文章
doi：10.1016/j.joen.2016.05.006
更新日期：2016-08-01 00:00:00
abstract：:The antibacterial activity of three commercial 10% carbamide peroxide bleaching agents (Nite White, Karisma, and Opalescence) on Streptococcus mutans, Streptococcus mitis, Streptococcus sanguis, Lactobacillus casei, and Lactobacillus acidophilus was examined. Chlorhexidine (0.2%) was used as a positive control. Test m...
journal_title：Journal of endodontics
pub_type： 杂志文章
doi：10.1016/S0099-2399(96)80217-2
更新日期：1996-07-01 00:00:00
abstract：INTRODUCTION:Porphyromonas gingivalis and Tannerella forsythia are anaerobic bacteria commonly involved in root canal infections. Although previous investigations have assessed these species by strictly qualitative approaches, accurate determination of their cell levels by a sensitive quantitative technique may contrib...
journal_title：Journal of endodontics
pub_type： 杂志文章
doi：10.1016/j.joen.2009.08.005
更新日期：2009-11-01 00:00:00
abstract：:The purpose of this study was to quantify the amount of remaining gutta-percha/sealer after retreatment of post space prepared teeth obturated with a lateral condensation technique or with Thermafil with plastic and metallic carrier. The time required for retreatment was also recorded. Forty-five extracted mandibular ...
journal_title：Journal of endodontics
pub_type： 杂志文章
doi：10.1016/s0099-2399(06)80019-1
更新日期：1994-01-01 00:00:00
abstract：INTRODUCTION:The aim of the present study was to compare sonic activation using EDDY (VDW, Munich, Germany), passive ultrasonic irrigation (PUI), and mechanical activation using the XPendo Finisher (FKG Dentaire, La Chaux-des-Fonds, Switzerland) for the removal of calcium hydroxide from artificial grooves in straight r...
journal_title：Journal of endodontics
pub_type： 杂志文章
doi：10.1016/j.joen.2018.11.001
更新日期：2019-03-01 00:00:00
abstract：INTRODUCTION:Calcium hydroxide has been used as a traditional pulpotomy agent for a long time but has some disadvantages. iRoot BP Plus (Innovative Bioceramix Inc, Vancouver, Canada) is a newly developed, ready-to-use calcium silicate-based bioactive ceramic with excellent bioactivity and sealing ability. However, whet...
journal_title：Journal of endodontics
pub_type： 杂志文章
doi：10.1016/j.joen.2019.12.010
更新日期：2020-03-01 00:00:00
abstract：INTRODUCTION:An ideal root canal sealer creates a bacteria-resistant seal and exhibits antimicrobial activity, biocompatibility, and osteoconductivity. The aim of this study was to assess the effects of 3 root canal sealers on cell viability, inflammatory response, and osteogenic potential in MC3T3-E1 cells. METHODS:A...
journal_title：Journal of endodontics
pub_type： 杂志文章
doi：10.1016/j.joen.2018.09.006
更新日期：2019-01-01 00:00:00
abstract：:The aim of this study was to investigate the correlation between endodontic clinical signs and symptoms and the presence of Porphyromonas gingivalis, Treponema denticola, and Tannerella forsythia or their association by nested polymerase chain reaction assay. Microbial samples were taken from 50 cases with necrotic pu...
journal_title：Journal of endodontics
pub_type： 杂志文章
doi：10.1016/j.joen.2007.05.017
更新日期：2007-09-01 00:00:00
abstract：INTRODUCTION:The dental pulp is highly vascularized and innervated tissue that is uniquely designed, being highly biologically active, while being enclosed within the calcified structure of the tooth. It is well-established that the dental pulp vasculature is a key requirement for the functional performance of the toot...
journal_title：Journal of endodontics
pub_type： 杂志文章
doi：10.1016/j.joen.2020.06.033
更新日期：2020-09-01 00:00:00
abstract：INTRODUCTION:The aim of this study was to assess temperature changes in conventional gutta-percha, thermoplastic gutta-percha, and Resilon cones by using thermomechanical compaction technique. METHODS:The root canals of extracted human teeth were placed in resin blocks and sectioned. After root canal preparation, cavi...
journal_title：Journal of endodontics
pub_type： 杂志文章
doi：10.1016/j.joen.2009.03.009
更新日期：2009-06-01 00:00:00
abstract：INTRODUCTION:The aim of this study was to assess the effect of nitrogen ion implantation on the flexibility of rotary nickel-titanium (NiTi) instruments as measured by the load required to bend implanted and nonimplanted instruments at a 30° angle. METHODS:Thirty K3 files, size #40, 0.02 taper and 25-mm length, were a...
journal_title：Journal of endodontics
pub_type： 杂志文章
doi：10.1016/j.joen.2012.01.012
更新日期：2012-05-01 00:00:00
abstract：INTRODUCTION:The treatment of immature necrotic permanent teeth presents several clinical challenges in endodontics. Regenerative endodontic procedures (REPs) permit root development, increased canal wall thickness, and apical closure. This longitudinal cohort study aimed to evaluate the long-term clinical and radiogra...
journal_title：Journal of endodontics
pub_type： 杂志文章
doi：10.1016/j.joen.2016.10.035
更新日期：2017-03-01 00:00:00
abstract：:This report describes the case of a patient with mesenchymal chondrosarcoma in the region of tooth #18 that mimicked apical periodontitis. Forty-five days after endodontic treatment, gingival swelling and intense pain were observed. The endodontist suspected a furcation lesion, and the treatment option that the patien...
journal_title：Journal of endodontics
pub_type： 杂志文章
doi：10.1016/j.joen.2008.08.016
更新日期：2008-11-01 00:00:00
abstract：:The purpose of this study was to investigate histologically and histometrically the changes in pulpal and periapical tissues after pulpal exposure in rats. All animals received a pulpal exposure in the left mandibular first molar. Animals were killed at 1 to 56 days after pulpal exposure, and their mandibles were eval...
journal_title：Journal of endodontics
pub_type： 杂志文章
doi：10.1016/s0099-2399(06)80020-8
更新日期：1994-01-01 00:00:00
abstract：INTRODUCTION:The aim of this study was to compare the sensitivity and specificity of cone-beam computed tomography (CBCT) scans and digital periapical radiographs (PR) in detecting strip and root perforations after root canal treatment in mandibular molars. METHODS:Forty-five curved mesial roots were endodontically pr...
journal_title：Journal of endodontics
pub_type： 杂志文章
doi：10.1016/j.joen.2010.12.003
更新日期：2011-04-01 00:00:00
