Longitudinal Cohort Study of Regenerative Endodontic Treatment for Immature Necrotic Permanent Teeth.

Abstract:

INTRODUCTION:The treatment of immature necrotic permanent teeth presents several clinical challenges in endodontics. Regenerative endodontic procedures (REPs) permit root development, increased canal wall thickness, and apical closure. This longitudinal cohort study aimed to evaluate the long-term clinical and radiographic outcomes of REPs of immature necrotic permanent teeth over a 30-month period. METHODS:This study was performed at the Division of Dentistry of the Montreal Children's Hospital, Montreal, Quebec, Canada. Twenty-eight immature necrotic permanent teeth from 22 patients were included in this study. All teeth were treated with a standardized REP protocol. Patients had follow-up appointments at 1, 2, 3, 6, 12, 18, 24, and 30 months. At each appointment, signs and symptoms were evaluated. Radiographic evaluation was also performed by a calibrated endodontist in order to analyze different parameters. RESULTS:Our results show a high survival rate (96.4%), clinical success (92.8%), and resolution of apical pathology (100%). Significant increases in the average root length (8.1%, P < .0001) and root thickness area (11.6%, P = .03) were observed after 30 months. In the study period, a significant decrease in the apical diameter was also noted, with 30.8% of the cases showing complete apical closure. Teeth with more immature stages of root development had a higher percentage of change in root thickness, length, and apical diameter; however, these results were not statistically significant. CONCLUSIONS:Teeth treated with REPs presented resolution of symptoms. Although clinical meaningful change was not achieved in all cases, increased root thickness, root length, and apical closure were observed at 30 months.

journal_name

J Endod

journal_title

Journal of endodontics

authors

Chan EK,Desmeules M,Cielecki M,Dabbagh B,Ferraz Dos Santos B

doi

10.1016/j.joen.2016.10.035

subject

Has Abstract

pub_date

2017-03-01 00:00:00

pages

395-400

issue

3

eissn

0099-2399

issn

1878-3554

pii

S0099-2399(16)30798-1

journal_volume

43

pub_type

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