Abstract：
:A new route for the design of renewable hydrogels is presented. The soluble waste from masonite production was isolated, fractionized, and upgraded. The resulting hemicellulose rich fraction was alkenyl-functionalized and used in the preparation of covalently cross-linked hydrogels capable of sustained release of incorporated agents. Said hydrogels showed a Fickian diffusion-based release of incorporated bovine serum albumin. Also, a method for the coating of seeds with hydrogel was developed. The sustained release of incorporated growth retardant agents from the hydrogel coating on rape seeds was shown to enable the temporary inhibition of germination.
journal_name
Biomacromoleculesjournal_title
Biomacromoleculesauthors
Albertsson AC,Voepel J,Edlund U,Dahlman O,Söderqvist-Lindblad Mdoi
10.1021/bm100253esubject
Has Abstractpub_date
2010-05-10 00:00:00pages
1406-11issue
5eissn
1525-7797issn
1526-4602journal_volume
11pub_type
杂志文章abstract：:Hybrid dendritic-linear block copolymers based on a 4-arm poly(ethylene glycol) (PEG) core were synthesized using an accelerated AB2/CD2 dendritic growth approach through orthogonal amine/epoxy and thiol-yne chemistries. The biological activity of these 4-arm and the corresponding 2-arm hybrid dendrimers revealed an e...
journal_title：Biomacromolecules
pub_type： 杂志文章
doi：10.1021/bm301384y
更新日期：2012-12-10 00:00:00
abstract：:Dynamic shear oscillation measurements at small strain were used to characterize the viscoelastic properties and related differences in the molecular structure of hydrogels based on gelatin methacrylamide. Gelatin was derivatized with methacrylamide side groups and was subsequently cross-linked by radical polymerizati...
journal_title：Biomacromolecules
pub_type： 杂志文章
doi：10.1021/bm990017d
更新日期：2000-04-01 00:00:00
abstract：:Silkworm silk has excellent mechanical properties, biocompatibility, and promising applications in the biomedical sector. Silkworms spin silk at the beginning and end of each of their five instar stages, as well as spinning mature silk after the fifth instar. We evaluated the mechanical properties and structure of 10 ...
journal_title：Biomacromolecules
pub_type： 杂志文章
doi：10.1021/acs.biomac.8b01576
更新日期：2019-03-11 00:00:00
abstract：:The first step in the conventional approach to self-assembled biomaterials is to develop well-defined nanostructures in vitro, which is followed by disruption of the preformed nanostructures at the inside of the cell to achieve bioactivity. Here, we propose an inverse strategy to develop in-cell gain-of-function self-...
journal_title：Biomacromolecules
pub_type： 杂志文章
doi：10.1021/acs.biomac.6b01816
更新日期：2017-03-13 00:00:00
abstract：:A polyethylene glycol (PEG) retinylamine (Ret-NH2) conjugate PEG-GFL-NH-Ret with a glycine-phenylalanine-leucine (GFL) spacer was synthesized for controlled oral delivery of Ret-NH2 to treat retinal degenerative diseases, including Stargardt disease (STGD) and age-related macular degeneration (AMD). The peptide spacer...
journal_title：Biomacromolecules
pub_type： 杂志文章
doi：10.1021/bm501352s
更新日期：2014-12-08 00:00:00
abstract：:Polymer therapeutics, including polymeric drugs and polymer-protein conjugates, are clinically established as first-generation nanomedicines. Knowing that the coiled-coil peptide motif is fundamentally important in the regulation of many cellular and pathological processes, the aim of these studies was to examine the ...
journal_title：Biomacromolecules
pub_type： 杂志文章
doi：10.1021/bm100843e
更新日期：2011-01-10 00:00:00
abstract：:Nanoconfined self-assemblies within aerosol nanoparticles and control of the secondary structures are shown here upon ionically complexing poly(L-lysine) (PLL) with dodecylbenzenesulfonic acid (DBSA) surfactant and using solvents chloroform, 1-propanol, or dimethylformamide. Different solvent volatilities and drying t...
journal_title：Biomacromolecules
pub_type： 杂志文章
doi：10.1021/bm500704e
更新日期：2014-07-14 00:00:00
abstract：:Inorganic polyphosphate (polyP) released by human platelets has recently been shown to activate blood clotting and identified as a potential target for the development of novel antithrombotics. Recent studies have shown that polymers with cationic binding groups (CBGs) inhibit polyP and attenuate thrombosis. However, ...
journal_title：Biomacromolecules
pub_type： 杂志文章
doi：10.1021/acs.biomac.8b00327
更新日期：2018-04-09 00:00:00
abstract：:A systematic study is carried out to understand how physical and covalent crosslinks affect the mechanical properties of an eight-arm poly(ethyleneglycol)-based hydrogel. Heparin and heparin-binding peptide are used as a physical crosslinker, and an enzymatically cleavable peptide with a cysteine on each end serves as...
journal_title：Biomacromolecules
pub_type： 杂志文章
doi：10.1021/bm801270k
更新日期：2009-05-11 00:00:00
abstract：:Hemicellulose-based hydrogels were prepared by radical polymerization of 2-hydroxyethyl methacrylate or poly(ethylene glycol) dimethacrylate with oligomeric hydrosoluble hemicellulose modified with well-defined amounts of methacrylic functions. The polymerization reaction was carried out in water at 40 degrees C using...
journal_title：Biomacromolecules
pub_type： 杂志文章
doi：10.1021/bm049515z
更新日期：2005-03-01 00:00:00
abstract：:Recent findings suggest that visible light-promoted photooxidative processes mediated by sensitizers of appropriate chemical structure could represent a useful tool for properly addressing the problem of the increasing occurrence of infectious diseases caused by multiantibiotic-resistant microbial pathogens. The monoc...
journal_title：Biomacromolecules
pub_type： 杂志文章
doi：10.1021/bm900533r
更新日期：2009-09-14 00:00:00
abstract：:The synthesis and polymerization of six AB(3) tapered self-assembling methacrylate monomers (5a, 5b, 5c,5d, 17a, and 17b) based on first generation alkyl substituted benzyl ether monodendrons (i.e., minidendrons) containing oligooxyethylene units at their focal point and the polymerizable group on their periphery are ...
journal_title：Biomacromolecules
pub_type： 杂志文章
doi：10.1021/bm010138p
更新日期：2002-01-01 00:00:00
abstract：:Single-molecule total internal reflection fluorescence microscopy was used to observe the dynamic behavior of polycytosine single-stranded DNA (ssDNA) (1-50 nucleotides long) at the interface between aqueous solution and hydrophilic (oligoethylene glycol-modified fused silica, OEG) and hydrophobic (octadecyltriethoxys...
journal_title：Biomacromolecules
pub_type： 杂志文章
doi：10.1021/bm301289n
更新日期：2012-12-10 00:00:00
abstract：:The growing importance of biodegradable conducting polymers (CPs) have fueled the rapid development of this unique class of polymeric materials in recent years. Possessing both the electrical conductivity approaching those of metallic conductors and the biodegradability of biocompatible polymers, biodegradable CPs are...
journal_title：Biomacromolecules
pub_type： 杂志文章,评审
doi：10.1021/acs.biomac.8b00275
更新日期：2018-06-11 00:00:00
abstract：:Candida antarctica Lipase B (CALB) was covalently immobilized onto epoxy-activated macroporous poly(methyl methacrylate) Amberzyme beads (235 microm particle size, 220 A pore size) and nanoparticles (nanoPSG, diameter 68 nm) with a poly(glycidyl methacrylate) outer region. Amberzyme beads allowed CALB loading up to 0....
journal_title：Biomacromolecules
pub_type： 杂志文章
doi：10.1021/bm700949x
更新日期：2008-02-01 00:00:00
abstract：:A strategy to manipulate the disulfide bond breaking triggered unfolding, and subsequently assembly of human serum albumin (HSA) in a lipophilic drug-dependent manner is present. In this study, the hydrophobic region, a molecular switch of the HSA, was regulated to form HSA-paclitaxel (HSA-PTX) nanoparticles by a faci...
journal_title：Biomacromolecules
pub_type： 杂志文章
doi：10.1021/bm201401s
更新日期：2012-01-09 00:00:00
abstract：:Control of the photoluminescence properties of cellulose is conducted by introduction of conducting polymers including fluorene (F) and 3-hexylthiophene (3HT) on cellulose surface through FeCl3 oxidative polymerization. The UV-vis absorption peak of cellulose grafted with the 3-hexylthiophene and fluorene copolymer wa...
journal_title：Biomacromolecules
pub_type： 杂志文章
doi：10.1021/acs.biomac.7b01067
更新日期：2017-12-11 00:00:00
abstract：:Fibrin sealants are a type of soft tissue adhesive that employs biochemical reactions from the late stages of the blood coagulation cascade. Intrinsic to these adhesives are a structural protein and a transglutaminase crosslinking enzyme. We are investigating an alternative biomimetic adhesive based on gelatin and a c...
journal_title：Biomacromolecules
pub_type： 杂志文章
doi：10.1021/bm034529a
更新日期：2004-07-01 00:00:00
abstract：:In situ cross-linkable hybrid hydrogels composed of gelatin and 4-arm-polypropylene oxide-polyethylene oxide (Tetronic) was developed as an injectable scaffold for tissue regeneration. The gelatin was modified by hydroxyphenyl propionic acid (HPA) and the Tetronic was conjugated with tyramines (Tet-TA). The hydrogels ...
journal_title：Biomacromolecules
pub_type： 杂志文章
doi：10.1021/bm201712z
更新日期：2012-03-12 00:00:00
abstract：:Chimeric DNA containing parallel (ps) and antiparallel (aps) duplex elements as well as poly-dC tracts were designed and synthesized. Oligonucleotide duplexes with ps chain orientation containing reverse Watson-Crick dA-dT base pairs and short d(C)2 tails are stabilized under slightly acidic conditions by hemiprotonat...
journal_title：Biomacromolecules
pub_type： 杂志文章
doi：10.1021/bm301471d
更新日期：2012-12-10 00:00:00
abstract：:Feasibility of using amphiphilic block copolymers composed of polylactide (PLA) and poly(ethylene oxide) (PEO) blocks for biomimetic surface modification of polylactide-based biomaterials for tissue engineering was investigated. PEO-b-PLA copolymers were deposited on the PLA surface from a solution in PEO-selective so...
journal_title：Biomacromolecules
pub_type： 杂志文章
doi：10.1021/bm900889b
更新日期：2010-01-11 00:00:00
abstract：:To continue expanding the use of Single Electron Transfer-Living Radical Polymerization (SET-LRP) in applications at the interface between macromolecular science, biomacromolecules, biology and medicine, it is essential to develop novel initiators that do not compromise the structural stability of synthesized polymers...
journal_title：Biomacromolecules
pub_type： 杂志文章
doi：10.1021/acs.biomac.7b00722
更新日期：2017-08-14 00:00:00
abstract：:Ephemeral gels, called Enzgels, successively undergo sol-gel and then gel-sol transition under the action of two antagonistic enzymes, transglutaminase and protease. Molecular and macroscopic properties of Enzgels are directly dependent on the enzymatic activities and their ratios. This work studies the characteristic...
journal_title：Biomacromolecules
pub_type： 杂志文章
doi：10.1021/bm700601n
更新日期：2008-01-01 00:00:00
abstract：:To broaden the application scope of lactic acid polymers, a new miniemulsion of poly(alkyl methacrylate-graft-lactic acid)s has been developed. The graft copolymer synthesis was based on a poly(lactic acid) macromonomer having a methacryloyl polymerizable group. The macromonomer and a comonomer of n-butyl methacrylate...
journal_title：Biomacromolecules
pub_type： 杂志文章
doi：10.1021/bm9007937
更新日期：2009-10-12 00:00:00
abstract：:We report an enzyme-based method for the in situ entrapment of cells within a biopolymeric hydrogel matrix. Specifically, we used a calcium-independent microbial transglutaminase that is known to cross-link proteins and observed that it catalyzes the formation of gels from a pre-gel solution containing 10% gelatin and...
journal_title：Biomacromolecules
pub_type： 杂志文章
doi：10.1021/bm034145k
更新日期：2003-11-01 00:00:00
abstract：:Recent developments in ionic liquid electrolytes for cellulose or biomass dissolution has also allowed for high-resolution 1H and 13C NMR on very high molecular weight cellulose. This permits the development of advanced liquid-state quantitative NMR methods for characterization of unsubstituted and low degree of subst...
journal_title：Biomacromolecules
pub_type： 杂志文章
doi：10.1021/acs.biomac.8b00295
更新日期：2018-07-09 00:00:00
abstract：:This work demonstrates that hydrogen peroxide (H2O2) is generated in weak polyacrylamide hydrogels due to mechanochemical reactions to osmotic swelling. Hydrogels are important tools and materials for many biomedical applications, particularly for growth of stem cells. However, swollen gels are under constant tension,...
journal_title：Biomacromolecules
pub_type： 杂志文章
doi：10.1021/acs.biomac.8b00743
更新日期：2018-08-13 00:00:00
abstract：:Nanoparticles (NPs) with high drug loading and pH-responsivity were prepared by nanoprecipitation of a hydrophobic polymer-drug conjugate (PDC). The PDC, polylactide-graft-doxorubicin (PLA-g-DOX), was synthesized by azide-alkyne click reaction to transform acetylene-functionalized PLA into PLA-graft-aldehyde (PLA-g-AL...
journal_title：Biomacromolecules
pub_type： 杂志文章
doi：10.1021/bm401471p
更新日期：2014-02-10 00:00:00
abstract：:This paper introduces a chitosan microneedle patch for efficient and sustained transdermal delivery of hydrophilic macromolecules. Chitosan microneedles have sufficient mechanical strength to be inserted in vitro into porcine skin at approximately 250 μm in depth and in vivo into rat skin at approximately 200 μm in de...
journal_title：Biomacromolecules
pub_type： 杂志文章
doi：10.1021/bm301293d
更新日期：2012-12-10 00:00:00
abstract：:Spiders spin their silk from an aqueous solution to a solid fiber in ambient conditions. However, to date, the assembly mechanism in the spider silk gland has not been satisfactorily explained. In this paper, we use molecular dynamics simulations to model Nephila clavipes MaSp1 dragline silk formation under shear flow...
journal_title：Biomacromolecules
pub_type： 杂志文章
doi：10.1021/acs.biomac.5b01246
更新日期：2016-02-08 00:00:00
