Biobased polymer system: miniemulsion of poly(alkyl methacrylate-graft-lactic acid)s.

abstract：:This study describes the preparation and the characterization of poly[ N-(2-hydroxypropyl methacrylamide)] hydrogel with bulk-modified saccharidic portion of ganglioside GM 3 (Neu5Ac-alpha2,3-Gal-beta1,4-Glc). The 3'-sialyllactose is a bioactive epitope recognized by many cell surface receptors on viruses, bacteria, a...

journal_title：Biomacromolecules

authors： Woerly S,Fort S,Pignot-Paintrand I,Cottet C,Carcenac C,Savasta M

更新日期：2008-09-01 00:00:00

abstract：:N-Acetyllactosamine (LacNAc; Galβ4GlcNAc) is a typical disaccharide ligand of galectins. The most abundant members of these human lectins, galectin-1 (Gal-1) and galectin-3 (Gal-3), participate in a number of pathologies including cancerogenesis and metastatic formation. In this study, we synthesized a series of fifte...

journal_title：Biomacromolecules

authors： Tavares MR,Bláhová M,Sedláková L,Elling L,Pelantová H,Konefał R,Etrych T,Křen V,Bojarová P,Chytil P

更新日期：2020-02-10 00:00:00

abstract：:Amphiphilic polymer conetworks (APCNs) are materials with a very large interface between their hydrophilic and hydrophobic phases due to their nanophase-separated morphologies. Proteins were found to enrich in APCNs by up to 2 orders of magnitude when incubated in aqueous protein solutions, raising the question of the...

journal_title：Biomacromolecules

authors： Dech S,Cramer T,Ladisch R,Bruns N,Tiller JC

更新日期：2011-05-09 00:00:00

abstract：:We report that the continuous assembly of polymers (CAP) approach, mediated by ring-opening metathesis polymerization (ROMP), is a facile and versatile technology to prepare engineered nanocoatings for various biomedical applications. Low-fouling coatings on particles were obtained by the formation of multicomposition...

journal_title：Biomacromolecules

authors： Guntari SN,Wong EH,Goh TK,Chandrawati R,Blencowe A,Caruso F,Qiao GG

更新日期：2013-08-12 00:00:00

abstract：:A novel strategy for artificial regulation system of gene expression applying the specific molecular recognition between carbohydrate and lectin is proposed. Plasmid-lactose conjugates (pActin-lactose and pGFP-lactose) prepared via diazocoupling maintained the transcription activity with T7 RNA polymerase. Gel-shift a...

journal_title：Biomacromolecules

authors： Matsuura K,Hayashi K,Kobayashi K

更新日期：2005-09-01 00:00:00

abstract：:The gold standard for implant metals is titanium, and coatings such as collagen-I, RGD-peptide, chondroitin sulfate, and calcium phosphate have been used to modify its biocompatibility. We investigated how titanium coated with pectins, adaptable bioactive plant polysaccharides with anti-inflammatory effects, supports ...

journal_title：Biomacromolecules

authors： Kokkonen H,Cassinelli C,Verhoef R,Morra M,Schols HA,Tuukkanen J

更新日期：2008-09-01 00:00:00

abstract：:Experimental and theoretical investigations of the swelling and mechanical properties of hydrogels formed from chitosan, bovine serum albumin (BSA), and chitosan/BSA mixtures cross-linked with genipin were performed. The properties of cross-linked chitosan hydrogels were explained in terms of its polyelectrolyte behav...

journal_title：Biomacromolecules

authors： Butler MF,Clark AH,Adams S

更新日期：2006-11-01 00:00:00

abstract：:On-line size-exclusion chromatography monitoring of potato phosphorylase catalyzed amylose synthesis--starting from alpha-D-glucose-1-P and maltohexaose--revealed rather monodisperse amylose populations. In the presence of lipids, amylose-lipid complexes spontaneously formed and precipitated. They were recovered by ce...

journal_title：Biomacromolecules

authors： Gelders GG,Goesaert H,Delcour JA

更新日期：2005-09-01 00:00:00

abstract：:Controlled reeling is a powerful tool to investigate the details of silk processing. However, consistent forced reeling of silkworms is hindered by the significant degree of behaviorally induced variation caused by the animal. This paper proposes silkworm paralysis as a novel method to control the animal and thus in v...

journal_title：Biomacromolecules

authors： Mortimer B,Holland C,Vollrath F

更新日期：2013-10-14 00:00:00

abstract：:Wheat arabinoxylan was treated with two α-arabinofuranosidases exhibiting different mode of action to create three different polymeric substrates. These three substrate preparations were characterized by xylopyranose backbone sugars that are (1) singly substituted by arabinose at C2 or C3, (2) doubly substituted by ar...

journal_title：Biomacromolecules

authors： Littunen K,Mai-Gisondi G,Seppälä J,Master ER

更新日期：2017-05-08 00:00:00

abstract：:Solid-state NMR is especially useful when the structures of peptides and proteins should be analyzed by taking into account the structural distribution, that is, the distribution of the torsion angle of the individual residue. In this study, two-dimensional spin-diffusion solid-state NMR spectra of 13C-double-labeled ...

journal_title：Biomacromolecules

authors： Ohgo K,Kawase T,Ashida J,Asakura T

更新日期：2006-04-01 00:00:00

abstract：:Poly(epsilon-caprolactone)/polylactide blend (PCL/PLA) is an interesting biomaterial because PCL and PLA present good complementarity in their physical properties and biodegradability. However, the thermodynamic incompatibility between two component polymers restricts further applications of their blend. In this work,...

journal_title：Biomacromolecules

authors： Wu D,Zhang Y,Zhang M,Yu W

更新日期：2009-02-09 00:00:00

abstract：:The morphologies of several ionotropic alginate hydrogels and aerogels were investigated by SAXS according to the nature of the divalent metal cation (Mn(2+), Co(2+), Zn(2+), Cu(2+)) and the guluronic fraction of the alginate. All alginate hydrogel and aerogel samples show isotropic small-angle X-ray scattering. Gelat...

journal_title：Biomacromolecules

authors： Agulhon P,Robitzer M,David L,Quignard F

更新日期：2012-01-09 00:00:00

abstract：:The adsorption of human immunoglobulin G (hIgG) and bovine serum albumin (BSA) on cellulose supports were investigated. The dynamics and extent of related adsorption processes were monitored by surface plasmon resonance (SPR) and quartz crystal microbalance with dissipation monitoring (QCM-D). Amine groups were instal...

journal_title：Biomacromolecules

authors： Orelma H,Filpponen I,Johansson LS,Laine J,Rojas OJ

更新日期：2011-12-12 00:00:00

abstract：:The objective of this study was to design GE11 peptide (YHWYGYTPQNVI) linked micelles of poly(ethylene glycol)-block-poly(2-methyl-2-carboxyl-propylene carbonate-graft-gemcitabine-graft-dodecanol (PEG-b-PCC-g-GEM-g-DC) for enhanced stability and target specificity of gemcitabine (GEM) to EGFR-positive pancreatic cance...

journal_title：Biomacromolecules

authors： Mondal G,Kumar V,Shukla SK,Singh PK,Mahato RI

更新日期：2016-01-11 00:00:00

abstract：:We synthesized positively charged biodegradable hydrogels by cross-linking of agmatine-modified poly(ethylene glycol)-tethered fumarate (Agm-PEGF) and poly(propylene fumarate-co-ethylene glycol) (P(PF-co-EG)) to investigate the effect of the guanidino groups of the agmatine on hydrogel swelling behavior and smooth mus...

journal_title：Biomacromolecules

authors： Tanahashi K,Jo S,Mikos AG

更新日期：2002-09-01 00:00:00

abstract：:To develop a safe, effective, and biocompatible gene delivery vector, a series of hydrophobic amino acid grafted chitosan (AGC) derivatives were synthesized by carbodiimide mediated coupling reaction. Chemical characterization of AGC polymers was performed by NMR and elemental analysis. AGC polymers demonstrated excel...

journal_title：Biomacromolecules

authors： Layek B,Singh J

更新日期：2013-02-11 00:00:00

abstract：:Polymer conjugation increases an enzyme's circulation time and stability for use as a therapeutic agent, but this attachment indubitably affects its properties. Covalent attachment of multiple polyethylene glycol chains with sizes of either 2, 5, 10, or 20 kDa increases the molecular weight and hydrodynamic radius of ...

journal_title：Biomacromolecules

authors： Chiu K,Agoubi LL,Lee I,Limpar MT,Lowe JW Jr,Goh SL

更新日期：2010-12-13 00:00:00

abstract：:We report the rational design of a chitosan-based drug delivery system. The chitosan derivative N-[(2-hydroxy-3-trimethylammonium)propyl]chitosan chloride (HTCC) was ionically cross-linked by sodium tripolyphosphate (TPP) to form sub-200-nm microgels that are responsive to pH changes. When these microgels were loaded ...

journal_title：Biomacromolecules

authors： Zhang H,Mardyani S,Chan WC,Kumacheva E

更新日期：2006-05-01 00:00:00

abstract：:Biobased omega-carboxy fatty acid monomers 1,18-cis-9-octadecenedioic, 1,22-cis-9-docosenedioic, and 1,18-cis-9,10-epoxy-octadecanedioic acids were synthesized in high conversion yields from oleic, erucic and epoxy stearic acids by whole-cell biotransformations catalyzed by C. tropicalis ATCC20962. Maximum volumetric ...

journal_title：Biomacromolecules

authors： Yang Y,Lu W,Zhang X,Xie W,Cai M,Gross RA

更新日期：2010-01-11 00:00:00

abstract：:The coefficient of thermal expansion (CTE) of cellulose nanocrystal (CNC) films was characterized using novel experimental techniques complemented by molecular simulations. The characteristic birefringence exhibited by CNC films was utilized to calculate the in-plane CTE of self-organized and shear-oriented self-stand...

journal_title：Biomacromolecules

authors： Diaz JA,Wu X,Martini A,Youngblood JP,Moon RJ

更新日期：2013-08-12 00:00:00

abstract：:The microstructure and the rheological properties of pure HM (high methoxyl) and LM (low methoxyl) pectin gels and of mixed HM/LM pectin gels have been investigated. Gel formation of either the HM or LM pectin, or both, was initiated in the mixed gels by varying the sucrose and Ca(2+) content. The microstructure was c...

journal_title：Biomacromolecules

authors： Löfgren C,Walkenström P,Hermansson AM

更新日期：2002-11-01 00:00:00

abstract：:The design of functional systems with sizes in the nanometer range is a key challenge in fields such as biomedicine, nanotechnology, and engineering. Some of the most promising materials nowadays consist of self-assembling peptides or peptide-polymer hybrid materials because of their versatility and the resulting prop...

journal_title：Biomacromolecules

authors： Mikhalevich V,Craciun I,Kyropoulou M,Palivan CG,Meier W

更新日期：2017-11-13 00:00:00

abstract：:It is an important challenge for bone repair to effectively deliver growth factors and at the same time to prevent and cure inflammation without obvious pathogen resistance. We designed a kind of antibacterial peptide-mimetic alternating copolymers (PMACs) to effectively inhibit and kill both Gram-positive and Gram-ne...

journal_title：Biomacromolecules

authors： Zhou C,Yuan Y,Zhou P,Wang F,Hong Y,Wang N,Xu S,Du J

更新日期：2017-12-11 00:00:00

abstract：:Cellular uptake and intracellular targeting to specific organelles are key events in the cellular processing of nanomaterials. Herein, we perform a detailed structure-property relationship study on carboxylic acid-side-chain-bearing polyacrylates to provide design criteria for the manipulation of their cellular intera...

journal_title：Biomacromolecules

authors： Mahmoud AM,Morrow JP,Pizzi D,Azizah AM,Davis TP,Tabor RF,Kempe K

更新日期：2020-08-10 00:00:00

abstract：:Polymeric prodrugs of mPEG-PLA-haloperidol (methoxypoly(ethylene glycol)-b-poly(lactic acid)) can self-assemble into nanoscale micelle-like structures in aqueous solutions. mPEG-PLA-haloperidol was prepared and characterized using 1H and 13C NMR. The conjugation efficiency was found to be 64.8 +/- 21%. Micelles that f...

journal_title：Biomacromolecules

authors： Hans M,Shimoni K,Danino D,Siegel SJ,Lowman A

更新日期：2005-09-01 00:00:00

abstract：:Bovine hemoglobin (Hb) was encapsulated inside polymer vesicles (polymersomes) to form polymersome encapsulated Hb (PEH) dispersions. PEH particles are 100% surface PEGylated with longer PEG chains and possess thicker hydrophobic membranes as compared to conventional liposomes. Polymersomes were self-assembled from po...

journal_title：Biomacromolecules

authors： Arifin DR,Palmer AF

更新日期：2005-07-01 00:00:00

abstract：:Solid films of deoxyribonucleic acid (DNA) containing a hydrated ionic liquid, choline dihydrogen phosphate (CDP), were prepared by a solvent-casting method. Thermal properties, aggregation structure, thermal molecular motion, and tensile properties of CDP-containing DNA films were examined by thermogravimetry (TG), w...

journal_title：Biomacromolecules

authors： Morimitsu Y,Matsuno H,Ohta N,Sekiguchi H,Takahara A,Tanaka K

更新日期：2020-02-10 00:00:00

abstract：:We report the synthesis of poly(methacrylic acid)-co-(oleyl methacrylate) with three different amounts of oleyl methacrylate and compare the ability of these polymers with that of poly(methacrylic acid)-co-(cholesteryl methacrylate) (PMA(c)) to noncovalently anchor liposomes to polymer layers. We subsequently assemble...

journal_title：Biomacromolecules

authors： Hosta-Rigau L,Chandrawati R,Saveriades E,Odermatt PD,Postma A,Ercole F,Breheney K,Wark KL,Städler B,Caruso F

更新日期：2010-12-13 00:00:00

abstract：:Bacterial biofilms tolerate extreme levels of antibiotics. Treatment of biofilm infections therefore requires the development of new or modified antimicrobials that can penetrate biofilms and are effective against dormant persistent cells. One such new approach uses the biodegradable biopolymer chitosan and its deriva...

journal_title：Biomacromolecules

authors： Sahariah P,Másson M,Meyer RL

更新日期：2018-09-10 00:00:00