Potato phosphorylase catalyzed synthesis of amylose-lipid complexes.

Abstract:

:On-line size-exclusion chromatography monitoring of potato phosphorylase catalyzed amylose synthesis--starting from alpha-D-glucose-1-P and maltohexaose--revealed rather monodisperse amylose populations. In the presence of lipids, amylose-lipid complexes spontaneously formed and precipitated. They were recovered by centrifugation, freeze-dried, and characterized by wide-angle X-ray diffraction and differential scanning calorimetry. The presence of lipids during amylose synthesis led to lower amylose degrees of polymerization (DP). Lipid chain length defined amylose DP, which increased in the order myristic acid (C14), glyceryl monostearate (GMS), stearic acid (C18), and docosanoic acid (C22). The thermal stability of the complexes increased in the same manner, with the C22 complexes having the highest dissociation temperature. In addition, we hypothesized that these results provide additional evidence for the fringed micellar organization of (semi-enzymically synthesized) amylose-lipid complexes.

journal_name

Biomacromolecules

journal_title

Biomacromolecules

authors

Gelders GG,Goesaert H,Delcour JA

doi

10.1021/bm0502011

keywords:

subject

Has Abstract

pub_date

2005-09-01 00:00:00

pages

2622-9

issue

5

eissn

1525-7797

issn

1526-4602

journal_volume

6

pub_type

杂志文章
  • Changes in glycogen structure over feeding cycle sheds new light on blood-glucose control.

    abstract::Liver glycogen, a highly branched polymer of glucose, is important for maintaining blood-glucose homeostasis. It was recently shown that db/db mice, a model for Type 2 diabetes, are unable to form the large composite glycogen α particles present in normal, healthy mice. In this study, the structure of healthy mouse-li...

    journal_title:Biomacromolecules

    pub_type: 杂志文章

    doi:10.1021/bm401714v

    authors: Sullivan MA,Aroney ST,Li S,Warren FJ,Joo JS,Mak KS,Stapleton DI,Bell-Anderson KS,Gilbert RG

    更新日期:2014-02-10 00:00:00

  • Sericin Promotes Fibroin Silk I Stabilization Across a Phase-Separation.

    abstract::Natural silk spinning offers several advantages over the synthetic fiber spinning, although the underlying mechanisms of this process are yet to be fully elucidated. Silkworm silks, specifically B. mori, comprise two main proteins: fibroin, which forms the fiber, and sericin, a coextruded coating that acts as a matrix...

    journal_title:Biomacromolecules

    pub_type: 杂志文章

    doi:10.1021/acs.biomac.7b00549

    authors: Kwak HW,Ju JE,Shin M,Holland C,Lee KH

    更新日期:2017-08-14 00:00:00

  • Photoluminescent porous alginate hybrid materials containing lanthanide ions.

    abstract::The photoluminescence features of Eu(3+)-, Tb(3+)-, Tb(3+)/Eu(3+)-alginate aerogel (hydrogel and alcogel) and Eu(3+)-alginate xerogel hybrids were investigated. The Eu(3+)-alginate aerogel and alcogel exhibit the highest (5)D0 quantum efficiencies (9.9 and 8.2%, respectively), while the hydrogel and xerogel have lower...

    journal_title:Biomacromolecules

    pub_type: 杂志文章

    doi:10.1021/bm8002122

    authors: Liu F,Carlos LD,Ferreira RA,Rocha J,Gaudino MC,Robitzer M,Quignard F

    更新日期:2008-07-01 00:00:00

  • Giant bent-core mesogens in the thread forming process of marine mussels.

    abstract::In marine mussels (Mytilus), byssal threads are made in minutes from prefabricated smectic polymer liquid crystals by a process resembling reaction injection molding. The mesogens in these arrays are known to be natural block copolymers with rodlike collagen cores. Using atomic force microscopy, it was shown that thes...

    journal_title:Biomacromolecules

    pub_type: 杂志文章

    doi:10.1021/bm049899t

    authors: Hassenkam T,Gutsmann T,Hansma P,Sagert J,Waite JH

    更新日期:2004-07-01 00:00:00

  • Thermoresponsive Self-Immolative Polyglyoxylamides.

    abstract::Thermoresponsive polymers with lower critical solution temperatures (LCSTs) are of significant interest for a wide range of applications from sensors to drug delivery vehicles. However, the most widely investigated LCST polymers have nondegradable backbones, limiting their applications in vivo or in the environment. D...

    journal_title:Biomacromolecules

    pub_type: 杂志文章

    doi:10.1021/acs.biomac.0c00899

    authors: Rabiee Kenaree A,Sirianni QEA,Classen K,Gillies ER

    更新日期:2020-09-14 00:00:00

  • Hemocompatible poly(NIPAm-MBA-AMPS) colloidal nanoparticles as carriers of anti-inflammatory cell penetrating peptides.

    abstract::Anionic copolymer systems containing sulfated monomers have great potential for delivery of cationic therapeutics, but N-isopropylacrylamide (NIPAm) 2-acrylamido-2-methyl-1-propanesulfonic acid (AMPS) copolymer nanoparticles have seen limited characterization to date with regard to physical properties relevant to load...

    journal_title:Biomacromolecules

    pub_type: 杂志文章

    doi:10.1021/bm300173x

    authors: Bartlett RL 2nd,Medow MR,Panitch A,Seal B

    更新日期:2012-04-09 00:00:00

  • Analysis of the conserved N-terminal domains in major ampullate spider silk proteins.

    abstract::Major ampullate silk, also known as dragline silk, is one of the strongest biomaterials known. This silk is composed of two proteins, major ampullate spidroin 1 (MaSp1) and major ampullate spidroin 2 (MaSp2). Only partial cDNA sequences have been obtained for these proteins, and these sequences are toward the C-termin...

    journal_title:Biomacromolecules

    pub_type: 杂志文章

    doi:10.1021/bm050472b

    authors: Motriuk-Smith D,Smith A,Hayashi CY,Lewis RV

    更新日期:2005-11-01 00:00:00

  • Polymers and Composites Derived from Castor Oil as Sustainable Materials and Degradable Biomaterials: Current Status and Emerging Trends.

    abstract::Recent years have seen rapid growth in utilizing vegetable oils to derive a wide variety of polymers to replace petroleum-based polymers for minimizing environmental impact. Nonedible castor oil (CO) can be extracted from castor plants that grow easily, even in an arid land. CO is a promising source for developing sev...

    journal_title:Biomacromolecules

    pub_type: 杂志文章

    doi:10.1021/acs.biomac.0c01291

    authors: Chakraborty I,Chatterjee K

    更新日期:2020-12-14 00:00:00

  • Surface charge of nanoparticles determines their endocytic and transcytotic pathway in polarized MDCK cells.

    abstract::A major challenge in drug delivery is the internalization through the apical plasma membrane of the polarized epithelial cells lining organs facing the external environment, e.g., lungs and the gastrointestinal tract. The reduced permeation of drugs entering through this pathway is in part due to the mucosal barrier a...

    journal_title:Biomacromolecules

    pub_type: 杂志文章

    doi:10.1021/bm700535p

    authors: Harush-Frenkel O,Rozentur E,Benita S,Altschuler Y

    更新日期:2008-02-01 00:00:00

  • Effect of size, surface charge, and hydrophobicity of poly(amidoamine) dendrimers on their skin penetration.

    abstract::The barrier functions of the stratum corneum and the epidermal layers present a tremendous challenge in achieving effective transdermal delivery of drug molecules. Although a few reports have shown that poly(amidoamine) (PAMAM) dendrimers are effective skin-penetration enhancers, little is known regarding the fundamen...

    journal_title:Biomacromolecules

    pub_type: 杂志文章

    doi:10.1021/bm300545b

    authors: Yang Y,Sunoqrot S,Stowell C,Ji J,Lee CW,Kim JW,Khan SA,Hong S

    更新日期:2012-07-09 00:00:00

  • Direct in vitro electrospinning with polymer melts.

    abstract::The electrospinning of polymer melts can offer an advantage over solution electrospinning, in the development of layered tissue constructs for tissue engineering. Melt electrospinning does not require a solvent, of which many are cytotoxic in nature, and the use of nonwater soluble polymers allows the collection of fi...

    journal_title:Biomacromolecules

    pub_type: 杂志文章

    doi:10.1021/bm050777q

    authors: Dalton PD,Klinkhammer K,Salber J,Klee D,Möller M

    更新日期:2006-03-01 00:00:00

  • Molecular dynamics study of complexes of poly(glutamate) and dodecyltrimethylammonium.

    abstract::The supramolecular organization of self-assembled stoichiometric complexes formed by dodecyltrimethylammonium cations and ionized poly(gamma-glutamic) acid has been investigated in chloroform solution. Atomistic molecular dynamics simulations have been performed considering three different starting conformations for t...

    journal_title:Biomacromolecules

    pub_type: 杂志文章

    doi:10.1021/bm060927c

    authors: Zanuy D,Alemán C

    更新日期:2007-02-01 00:00:00

  • Microstructure and rheological behavior of pure and mixed pectin gels.

    abstract::The microstructure and the rheological properties of pure HM (high methoxyl) and LM (low methoxyl) pectin gels and of mixed HM/LM pectin gels have been investigated. Gel formation of either the HM or LM pectin, or both, was initiated in the mixed gels by varying the sucrose and Ca(2+) content. The microstructure was c...

    journal_title:Biomacromolecules

    pub_type: 杂志文章

    doi:10.1021/bm020044v

    authors: Löfgren C,Walkenström P,Hermansson AM

    更新日期:2002-11-01 00:00:00

  • Effects of base polymer hydrophobicity and end-group modification on polymeric gene delivery.

    abstract::A new 320-member polymer library of end-modified poly(β-amino ester)s was synthesized. This library was chosen such that small differences to the structures of component backbone, side-chain, and end-group monomers could be systematically and simultaneously evaluated. The in vitro transfection efficacy and cytotoxicit...

    journal_title:Biomacromolecules

    pub_type: 杂志文章

    doi:10.1021/bm200807s

    authors: Sunshine JC,Akanda MI,Li D,Kozielski KL,Green JJ

    更新日期:2011-10-10 00:00:00

  • Injectable Polypeptide Hydrogels with Tunable Microenvironment for 3D Spreading and Chondrogenic Differentiation of Bone-Marrow-Derived Mesenchymal Stem Cells.

    abstract::Bone-marrow-derived mesenchymal stem cells (BMSCs) possess vast potential for tissue engineering and regenerative medicine. In this study, an injectable hydrogel comprising poly(l-glutamic acid)-graft-tyramine (PLG-g-TA) with tunable microenvironment was developed via enzyme-catalyzed cross-linking and used as an arti...

    journal_title:Biomacromolecules

    pub_type: 杂志文章

    doi:10.1021/acs.biomac.6b00884

    authors: Ren K,Cui H,Xu Q,He C,Li G,Chen X

    更新日期:2016-12-12 00:00:00

  • Hydration of gluten: a dielectric, calorimetric, and fourier transform infrared study.

    abstract::The nature of the hydration of proteins and the subsequent implications for functionality is a matter of importance in both pharmaceutical and food applications. Most published studies rely on the use of one technique and attempt to characterize the system. Few studies have used combinations of techniques. In this pap...

    journal_title:Biomacromolecules

    pub_type: 杂志文章

    doi:10.1021/bm061206g

    authors: Almutawah A,Barker SA,Belton PS

    更新日期:2007-05-01 00:00:00

  • Analysis using a linear viscoelastic model of the in vitro osmotic kinetics of polydisperse synthetic colloids.

    abstract::This study clarifies the contribution to overall osmotic kinetics of colloid osmotic pressure (Pi) and the interaction of synthetic colloids with the membrane. Solutions (6%) of dextran with weight average molecular weight (MW(w)) 68 800 (DEX 70), dextran with MW(w) 40 000 (DEX 40), hydroxyethyl starch with MW(w) 70 0...

    journal_title:Biomacromolecules

    pub_type: 杂志文章

    doi:10.1021/bm0500143

    authors: Tatara T,Tashiro C

    更新日期:2005-05-01 00:00:00

  • Artificial forisomes are ideal models of forisome assembly and activity that allow the development of technical devices.

    abstract::Forisomes are protein polymers found in leguminous plants that have the remarkable ability to undergo reversible "muscle-like" contractions in the presence of divalent cations and in extreme pH environments. To gain insight into the molecular basis of forisome structure and assembly, we used confocal laser scanning mi...

    journal_title:Biomacromolecules

    pub_type: 杂志文章

    doi:10.1021/bm3008499

    authors: Groscurth S,Müller B,Schwan S,Menzel M,Diekstall F,Senft M,Kendall A,Kommor BA,Neumann U,Kalischuk M,Kawchuk LM,Krzyzanek V,Heilmann A,Stubbs G,Twyman RM,Prüfer D,Noll GA

    更新日期:2012-10-08 00:00:00

  • Noninvasive in vivo monitoring of the biofate of 195 kDa poly(vinyl alcohol) by multispectral fluorescence imaging.

    abstract::A comprehensive knowledge of the in vivo fate of polymers is essential for their potential application in humans. In this study, the body distribution, accumulation, and elimination processes of intraperitoneally (ip) administered poly(vinyl alcohol) (PVA) in mice were investigated in detail. Two derivatives of PVA (1...

    journal_title:Biomacromolecules

    pub_type: 杂志文章

    doi:10.1021/bm200899h

    authors: Schädlich A,Naolou T,Amado E,Schöps R,Kressler J,Mäder K

    更新日期:2011-10-10 00:00:00

  • Biobased polymer system: miniemulsion of poly(alkyl methacrylate-graft-lactic acid)s.

    abstract::To broaden the application scope of lactic acid polymers, a new miniemulsion of poly(alkyl methacrylate-graft-lactic acid)s has been developed. The graft copolymer synthesis was based on a poly(lactic acid) macromonomer having a methacryloyl polymerizable group. The macromonomer and a comonomer of n-butyl methacrylate...

    journal_title:Biomacromolecules

    pub_type: 杂志文章

    doi:10.1021/bm9007937

    authors: Ishimoto K,Arimoto M,Ohara H,Kobayashi S,Ishii M,Morita K,Yamashita H,Yabuuchi N

    更新日期:2009-10-12 00:00:00

  • Wormlike Nanovector with Enhanced Drug Loading Using Blends of Biodegradable Block Copolymers.

    abstract::The application of nanoparticles comprising amphiphilic block copolymers for the delivery of drugs is a subject of great interest as they hold promise for more effective and selective therapies. In order to achieve this ambition, it is of critical importance to develop our understanding of the self-assembly mechanisms...

    journal_title:Biomacromolecules

    pub_type: 杂志文章

    doi:10.1021/acs.biomac.0c00169

    authors: Ridolfo R,Arends JJ,van Hest JCM,Williams DS

    更新日期:2020-06-08 00:00:00

  • Exploration of Blood Coagulation of N-Alkyl Chitosan Nanofiber Membrane in Vitro.

    abstract::N-Alkylated chitosan (NACS) may improve the blood clotting efficiency of chitosan (CS). To study its blood coagulation capability, a series of NACSs with various carbon chain lengths and degrees of substitution (DS) of alkyl groups were synthesized and characterized by FTIR, NMR, elemental analysis, and X-ray diffract...

    journal_title:Biomacromolecules

    pub_type: 杂志文章

    doi:10.1021/acs.biomac.7b01492

    authors: Wang X,Guan J,Zhuang X,Li Z,Huang S,Yang J,Liu C,Li F,Tian F,Wu J,Shu Z

    更新日期:2018-03-12 00:00:00

  • Study on the conversion of wool keratin by steam explosion.

    abstract::A wool fiber sample was submitted to chemical-free steam explosion in view of potential exploitation of keratin-based industrial and farm wastes. Fiber keratin was converted into a dark-yellow sludge that was submitted to phase separation by filtration, centrifugation, and precipitation of the soluble materials from t...

    journal_title:Biomacromolecules

    pub_type: 杂志文章

    doi:10.1021/bm060597w

    authors: Tonin C,Zoccola M,Aluigi A,Varesano A,Montarsolo A,Vineis C,Zimbardi F

    更新日期:2006-12-01 00:00:00

  • Polyhydroxybutyrate Bioresins with High Thermal Stability by Cross-linking with Resorcinol Diglycidyl Ether.

    abstract::The development of sustainable materials by employing natural and nontoxic resources has been attracting much attention over the previous years. In this work, we discuss for the first time the chemical combination between resorcinol diglycidyl ether (RDGE), an aromatic biobased thermosetting monomer, and polyhydroxybu...

    journal_title:Biomacromolecules

    pub_type: 杂志文章

    doi:10.1021/acs.biomac.0c00876

    authors: Cantarutti C,Dinu R,Mija A

    更新日期:2020-08-10 00:00:00

  • An approach to modulate degradation and mesenchymal stem cell behavior in poly(ethylene glycol) networks.

    abstract::A simple, sequential approach for creation of hydrolytically degradable poly(ethylene glycol) (PEG) hydrogels has been developed and characterized. The chemistry involves an initial step growth polymerization reaction between PEG-diacrylate and dithiothreitol (DTT) to form acrylate-terminated (-PEG-DTT-)n PEG chains, ...

    journal_title:Biomacromolecules

    pub_type: 杂志文章

    doi:10.1021/bm701179s

    authors: Hudalla GA,Eng TS,Murphy WL

    更新日期:2008-03-01 00:00:00

  • Polymer-Upconverting Nanoparticle Hybrid Micelles for Enhanced Synergistic Chemo-Photodynamic Therapy: Effects of Emission-Absorption Spectral Match.

    abstract::Chemo-photodynamic combined therapy is promising in cancer treatment, although low tissue penetration of visible light for activating photosensitizers (e.g., chlorin e6, Ce6) limited its broad applications. Combination of upcoverting nanoparticles (UCNPs) with the photosensitizers endows us with the possibility to uti...

    journal_title:Biomacromolecules

    pub_type: 杂志文章

    doi:10.1021/acs.biomac.9b01211

    authors: Chen Y,Ren J,Tian D,Li Y,Jiang H,Zhu J

    更新日期:2019-10-14 00:00:00

  • Two-Dimensional Supramolecular Assemblies from pH-Responsive Poly(ethyl glycol)-b-poly(l-glutamic acid)-b-poly(N-octylglycine) Triblock Copolymer.

    abstract::Amphiphilic block copolymers containing polypeptides can self-assemble into a variety of nonspherical structures arising from strong interactions between peptide units. Here, we report the synthesis of a pH-responsive poly(ethyl glycol)-block-poly(l-glutamic acid)-block-poly(N-octylglycine) (PEG-b-PGA-b-PNOG) triblock...

    journal_title:Biomacromolecules

    pub_type: 杂志文章

    doi:10.1021/acs.biomac.7b01014

    authors: Ni Y,Sun J,Wei Y,Fu X,Zhu C,Li Z

    更新日期:2017-10-09 00:00:00

  • Modular elastic patches: mechanical and biological effects.

    abstract::A modular approach to engineering cross-linked elastic biomaterials is presented for fine-tuning of material mechanical and biological properties. The three components, soluble elastin, hyaluronic acid, and silk fibroin, contribute with different features to the overall properties of the final material system. The ela...

    journal_title:Biomacromolecules

    pub_type: 杂志文章

    doi:10.1021/bm1007772

    authors: Serban MA,Kluge JA,Laha MM,Kaplan DL

    更新日期:2010-09-13 00:00:00

  • Synthesis and characterization of core-shell star copolymers for in vivo PET imaging applications.

    abstract::The synthesis of core-shell star copolymers via living free radical polymerization provides a convenient route to three-dimensional nanostructures having a poly(ethylene glycol) outer shell, a hydrophilic inner shell bearing reactive functional groups, and a central hydrophobic core. By starting with well-defined line...

    journal_title:Biomacromolecules

    pub_type: 杂志文章

    doi:10.1021/bm7014152

    authors: Fukukawa K,Rossin R,Hagooly A,Pressly ED,Hunt JN,Messmore BW,Wooley KL,Welch MJ,Hawker CJ

    更新日期:2008-04-01 00:00:00

  • An Injectable Hydrogel Prepared Using a PEG/Vitamin E Copolymer Facilitating Aqueous-Driven Gelation.

    abstract::Hydrogels have been widely explored for biomedical applications, with injectable hydrogels being of particular interest for their ability to precisely deliver drugs and cells to targets. Although these hydrogels have demonstrated satisfactory properties in many cases, challenges still remain for commercialization. In ...

    journal_title:Biomacromolecules

    pub_type: 杂志文章

    doi:10.1021/acs.biomac.6b01148

    authors: Zhang J,Muirhead B,Dodd M,Liu L,Xu F,Mangiacotte N,Hoare T,Sheardown H

    更新日期:2016-11-14 00:00:00