Selective localization of multiwalled carbon nanotubes in poly(epsilon-caprolactone)/polylactide blend.


:Poly(epsilon-caprolactone)/polylactide blend (PCL/PLA) is an interesting biomaterial because PCL and PLA present good complementarity in their physical properties and biodegradability. However, the thermodynamic incompatibility between two component polymers restricts further applications of their blend. In this work, we used functionalized multiwalled carbon nanotube (MWCNT) to control the morphology of immiscible PCL/PLA blend. The ternary PCL/PLA/MWCNTs composites were hence prepared by melt mixing for the morphology and the properties investigation. It is interesting to find that the functionalized MWCNTs are selectively dispersed in the matrix PCL phase and on the interface between two polymer phases, leading to simultaneous occurrence of thermodynamically and kinetically driven compatibility. Those interface-localized MWCNTs prevent coalescence of the discrete domains and enhance the phase interfacial adhesion as well. As a result, the phase morphology of the ternary composites is improved remarkably in contrast to that of the blank PCL/PLA blend. Owing to that unique selective interface-localization and improved phase morphology, the ternary composites present far lower rheological and conductive percolation thresholds than those of the binary composites, and also present extraordinary mechanical properties even at very low loading levels of the MWCNTs. Therefore, the amphiphilic MWCNTs are believed to act as the reinforcements as well as the compatibilizer in the immiscible PCL/PLA blend.






Wu D,Zhang Y,Zhang M,Yu W




Has Abstract


2009-02-09 00:00:00














  • Effects of temperature and pressure on the aggregation properties of an engineered elastin model polypeptide in aqueous solution.

    abstract::The pressure and temperature dependence of the cloud point transition of an aqueous solution of an elastin-like polypeptide (MGLDGSMG(VPGIG)40VPLE), prepared by bacterial expression of the corresponding artificial gene, was measured. A temperature-pressure diagram was constructed over a wide range of conditions. The (...


    pub_type: 杂志文章


    authors: Tamura T,Yamaoka T,Kunugi S,Panitch A,Tirrell DA

    更新日期:2000-01-01 00:00:00

  • Design of renewable hydrogel release systems from fiberboard mill wastewater.

    abstract::A new route for the design of renewable hydrogels is presented. The soluble waste from masonite production was isolated, fractionized, and upgraded. The resulting hemicellulose rich fraction was alkenyl-functionalized and used in the preparation of covalently cross-linked hydrogels capable of sustained release of inco...


    pub_type: 杂志文章


    authors: Albertsson AC,Voepel J,Edlund U,Dahlman O,Söderqvist-Lindblad M

    更新日期:2010-05-10 00:00:00

  • Protective effects and mechanisms of G5 PAMAM dendrimers against acute pancreatitis induced by caerulein in mice.

    abstract::In this study, generation 5 (G5) polyamidoamine (PAMAM) dendrimers with two different surface groups, G4.5-COOH and G5-OH, were investigated for their protective effects on pancreas injury in a caerulein-induced acute pancreatitis (AP) mouse model. Both dendrimers significantly decreased pathological changes in the pa...


    pub_type: 杂志文章


    authors: Tang Y,Han Y,Liu L,Shen W,Zhang H,Wang Y,Cui X,Wang Y,Liu G,Qi R

    更新日期:2015-01-12 00:00:00

  • Modulation of cellulose nanocrystals amphiphilic properties to stabilize oil/water interface.

    abstract::Neutral cellulose nanocrystals dispersed in water were shown in a previous work to stabilize oil/water interfaces and produce Pickering emulsions with outstanding stability, whereas sulfated nanocrystals obtained from cotton did not show interfacial properties. To develop a better understanding of the stabilization me...


    pub_type: 杂志文章


    authors: Kalashnikova I,Bizot H,Cathala B,Capron I

    更新日期:2012-01-09 00:00:00

  • Advanced Cellulose Fibers for Efficient Immobilization of Enzymes.

    abstract::Biocatalytic pulp fibers were prepared using surface functionalization of bleached kraft pulp with amino groups (F) and further immobilization of a cross-linked glucose oxidase (G*) from Aspergillus niger. The cross-linked enzymes (G*) were characterized using X-ray spectroscopy, Fourier transform infrared spectroscop...


    pub_type: 杂志文章


    authors: Vega Erramuspe IB,Fazeli E,Näreoja T,Trygg J,Hänninen P,Heinze T,Fardim P

    更新日期:2016-10-10 00:00:00

  • α-Synuclein Penetrates Mucin Hydrogels Despite Its Mucoadhesive Properties.

    abstract::Recent research indicates that the progression of Parkinson's disease can start from neurons of the enteric nervous system, which are in close contact with the gastrointestinal epithelium: α-synuclein molecules can be transferred from these epithelial cells in a prion-like fashion to enteric neurons. Thin mucus layers...


    pub_type: 杂志文章


    authors: Marczynski M,Rickert CA,Semerdzhiev SA,van Dijk WR,Segers-Nolten IMJ,Claessens MMAE,Lieleg O

    更新日期:2019-12-09 00:00:00

  • Reversibility of structural changes of polypeptides in multilayer nanofilms.

    abstract::Structural properties of different polypeptide multilayer nanofilms fabricated at neutral pH have been analyzed by UV spectroscopy, circular dichroism spectroscopy (CD), and Fourier-transform infrared spectroscopy (FTIR). The various peptides studied exhibit a strong tendency to adopt a beta sheet conformation in the ...


    pub_type: 杂志文章


    authors: Zhang L,Haynie DT

    更新日期:2008-01-01 00:00:00

  • Highly Effective Antibacterial Vesicles Based on Peptide-Mimetic Alternating Copolymers for Bone Repair.

    abstract::It is an important challenge for bone repair to effectively deliver growth factors and at the same time to prevent and cure inflammation without obvious pathogen resistance. We designed a kind of antibacterial peptide-mimetic alternating copolymers (PMACs) to effectively inhibit and kill both Gram-positive and Gram-ne...


    pub_type: 杂志文章


    authors: Zhou C,Yuan Y,Zhou P,Wang F,Hong Y,Wang N,Xu S,Du J

    更新日期:2017-12-11 00:00:00

  • Synthesis, characterization, and bioavailability of mannosylated shell cross-linked nanoparticles.

    abstract::Saccharide-functionalized shell cross-linked (SCK) polymer micelles designed as polyvalent nanoscaffolds for selective interactions with receptors on Gram negative bacteria were constructed from mixed micelles composed of poly(acrylic acid-b-methyl acrylate) and mannosylated poly(acrylic acid-b-methyl acrylate). The m...


    pub_type: 杂志文章


    authors: Joralemon MJ,Murthy KS,Remsen EE,Becker ML,Wooley KL

    更新日期:2004-05-01 00:00:00

  • Structural differences between the lignin-carbohydrate complexes present in wood and in chemical pulps.

    abstract::Lignin-carbohydrate complexes (LCCs) were prepared in quantitative yield from spruce wood and from the corresponding kraft and oxygen-delignified pulps and were separated into different fractions on the basis of their carbohydrate composition. To obtain an understanding of the differences in lignin structure and react...


    pub_type: 杂志文章


    authors: Lawoko M,Henriksson G,Gellerstedt G

    更新日期:2005-11-01 00:00:00

  • Synthesis, characterization, and preliminary biological study of poly(3-(tert-butoxycarbonyl)-N-vinyl-2-pyrrolidone).

    abstract::Poly(3-(tert-butoxycarbonyl)-N-vinyl-2-pyrrolidone) has been synthesized and characterized by gel permeation chromatography, Fourier transform infrared spectroscopy, NMR spectroscopy, and thermal analysis. The polymer is a chemically amplified photoresist. Arrays of lines with 25 microm width and 25 microm spacing wer...


    pub_type: 杂志文章


    authors: He W,Gonsalves KE,Pickett JH,Halberstadt C

    更新日期:2003-01-01 00:00:00

  • Alterations in mucus barrier function and matrix structure induced by guluronate oligomers.

    abstract::The effect of guluronate oligomers on the barrier properties of mucous matrices was investigated in terms of the mobility of nanoparticles in mucous matrices by fluorescence recovery after photobleaching (FRAP), cellular uptake of nanoparticles in mucus secreting cells (HT29-MTX), and mucin matrix architecture by scan...


    pub_type: 杂志文章


    authors: Nordgård CT,Nonstad U,Olderøy MØ,Espevik T,Draget KI

    更新日期:2014-06-09 00:00:00

  • Structural analysis of enzyme-resistant isomaltooligosaccharides reveals the elongation of α-(1→3)-linked branches in Weissella confusa dextran.

    abstract::Weissella confusa VTT E-90392 is an efficient producer of a dextran that is mainly composed of α-(1→6)-linked D-glucosyl units and very few α-(1→3) branch linkages. A mixture of the Chaetomium erraticum endodextranase and the Aspergillus niger α-glucosidase was used to hydrolyze W. confusa dextran to glucose and a set...


    pub_type: 杂志文章


    authors: Maina NH,Virkki L,Pynnönen H,Maaheimo H,Tenkanen M

    更新日期:2011-02-14 00:00:00

  • Block versus random amphiphilic copolymers as antibacterial agents.

    abstract::We examined the antibacterial and hemolytic activities in a series of amphiphilic block and random copolymers of poly(vinyl ether) derivatives prepared by base-assisting living cationic polymerization. Block and random amphiphilic copolymers with similar monomer compositions showed the same level of activity against ...


    pub_type: 杂志文章


    authors: Oda Y,Kanaoka S,Sato T,Aoshima S,Kuroda K

    更新日期:2011-10-10 00:00:00

  • A Universal Approach to Render Nanomedicine with Biological Identity Derived from Cell Membranes.

    abstract::Biomimetic nanoengineering built through integrating the specific cell membrane with artificially synthetic nanomedicines represents one of the most promising directions for the actualization of personalized therapy. For addressing the technical hurdle against the development of this biomimetic technology, the present...


    pub_type: 杂志文章


    authors: Zhu J,Zhang M,Zheng D,Hong S,Feng J,Zhang XZ

    更新日期:2018-06-11 00:00:00

  • Spectral properties and DNA targeting features of a thiazole orange-peptide bioconjugate.

    abstract::The molecular recognition features of a DNA-sensitive fluorescent bioconjugate capable of targeting a specific DNA sequence with high efficiency are described. The bioconjugate combines a polypeptide from the Tc3 transposase DNA-binding domain with the dsDNA-sensitive fluorophore thiazole orange. Fluorescence spectros...


    pub_type: 杂志文章


    authors: Thompson M

    更新日期:2007-11-01 00:00:00

  • Enzymatic polymerization to novel polysaccharides having a glucose-N-acetylglucosamine repeating unit, a cellulose-chitin hybrid polysaccharide.

    abstract::A cellulose-chitin hybrid polysaccharide having alternatingly beta(1-->4)-linked D-glucose (Glc) and N-acetyl-d-glucosamine (GlcNAc) was synthesized via two modes of enzymatic polymerization. First, a sugar oxazoline monomer of Glcbeta(1-->4)GlcNAc (1) was designed as a transition-state analogue substrate (TSAS) monom...


    pub_type: 杂志文章


    authors: Kobayashi S,Makino A,Matsumoto H,Kunii S,Ohmae M,Kiyosada T,Makiguchi K,Matsumoto A,Horie M,Shoda S

    更新日期:2006-05-01 00:00:00

  • An approach to modulate degradation and mesenchymal stem cell behavior in poly(ethylene glycol) networks.

    abstract::A simple, sequential approach for creation of hydrolytically degradable poly(ethylene glycol) (PEG) hydrogels has been developed and characterized. The chemistry involves an initial step growth polymerization reaction between PEG-diacrylate and dithiothreitol (DTT) to form acrylate-terminated (-PEG-DTT-)n PEG chains, ...


    pub_type: 杂志文章


    authors: Hudalla GA,Eng TS,Murphy WL

    更新日期:2008-03-01 00:00:00

  • Oxidized alginate-cross-linked alginate/gelatin hydrogel fibers for fabricating tubular constructs with layered smooth muscle cells and endothelial cells in collagen gels.

    abstract::Hydrogel fibers that possessed a cell-adhesive surface and were degradable via enzymatic reactions were developed for fabricating tubular constructs with smooth muscle cell (SMC) and endothelial cell (EC) layers, similar to native blood vessels, in collagen gels. The fibers were prepared by soaking hydrogel fibers pre...


    pub_type: 杂志文章


    authors: Sakai S,Yamaguchi S,Takei T,Kawakami K

    更新日期:2008-07-01 00:00:00

  • Antibiofilm Synergy of β-Lactams and Branched Polyethylenimine against Methicillin-Resistant Staphylococcus epidermidis.

    abstract::Microbial biofilms are ubiquitous in nature, and they pose a serious threat to public health. Staphylococcus epidermidis is the most common clinical isolate from healthcare- and medical device-related biofilm infections. No antibiotic currently on the market can eradicate pathogenic biofilms, which contain complex def...


    pub_type: 杂志文章


    authors: Lam AK,Wouters CL,Moen EL,Pusavat J,Rice CV

    更新日期:2019-10-14 00:00:00

  • Altering peptide fibrillization by polymer conjugation.

    abstract::A strategy is presented that exploits the ability of synthetic polymers of different nature to disturb the strong self-assembly capabilities of amyloid based β-sheet forming peptides. Following a convergent approach, the peptides of interest were synthesized via solid-phase peptide synthesis (SPPS) and the polymers vi...


    pub_type: 杂志文章


    authors: Dehn S,Castelletto V,Hamley IW,Perrier S

    更新日期:2012-09-10 00:00:00

  • An RNA Aptamer Capable of Forming a Hydrogel by Self-Assembly.

    abstract::Hydrogels are supramolecular assemblies with both solute transport properties like liquids and mechanical properties like elastomers. To date, every type of biomolecules except ribonucleic acid (RNA), is capable of forming a hydrogel. Here, we report an RNA that forms a hydrogel by self-assembly. This RNA is originall...


    pub_type: 杂志文章


    authors: Huang Z,Kangovi GN,Wen W,Lee S,Niu L

    更新日期:2017-07-10 00:00:00

  • Carrageenan-based hydrogels for the controlled delivery of PDGF-BB in bone tissue engineering applications.

    abstract::One of the major drawbacks found in most bone tissue engineering approaches developed so far consists in the lack of strategies to promote vascularisation. Some studies have addressed different issues that may enhance vascularisation in tissue engineered constructs, most of them involving the use of growth factors (GF...


    pub_type: 杂志文章


    authors: Santo VE,Frias AM,Carida M,Cancedda R,Gomes ME,Mano JF,Reis RL

    更新日期:2009-06-08 00:00:00

  • Electrospinning Bombyx mori silk with poly(ethylene oxide).

    abstract::Electrospinning for the formation of nanoscale diameter fibers has been explored for high-performance filters and biomaterial scaffolds for vascular grafts or wound dressings. Fibers with nanoscale diameters provide benefits due to high surface area. In the present study we explore electrospinning for protein-based bi...


    pub_type: 杂志文章


    authors: Jin HJ,Fridrikh SV,Rutledge GC,Kaplan DL

    更新日期:2002-11-01 00:00:00

  • ATP-Responsive Low-Molecular-Weight Polyethylenimine-Based Supramolecular Assembly via Host-Guest Interaction for Gene Delivery.

    abstract::In this work, we report on an ATP-responsive low-molecular-weight polyethylenimine (LMW-PEI)-based supramolecular assembly. It formed via host-guest interaction between PEI (MW = 1.8 kDa)-α-cyclodextrin (α-CD) conjugates and PEI1.8k-phenylboronic acid (PBA) conjugates. The host-guest interaction between PEI1.8k-α-CD a...


    pub_type: 杂志文章


    authors: Jiang C,Qi Z,Jia H,Huang Y,Wang Y,Zhang W,Wu Z,Yang H,Liu J

    更新日期:2019-01-14 00:00:00

  • Influence of Molecular Structure on the In Vivo Performance of Flexible Rod Polyrotaxanes.

    abstract::Polyrotaxanes, a family of rod-shaped nanomaterials comprised of noncovalent polymer/macrocycle assemblies, are being used in a growing number of materials and biomedical applications. Their physiochemical properties can vary widely as a function of composition, potentially leading to different in vivo performance out...


    pub_type: 杂志文章


    authors: Collins CJ,Mondjinou Y,Loren B,Torregrosa-Allen S,Simmons CJ,Elzey BD,Ayat N,Lu ZR,Thompson D

    更新日期:2016-09-12 00:00:00

  • Mutational analysis and allosteric effects in the HIV-1 capsid protein carboxyl-terminal dimerization domain.

    abstract::The carboxyl-terminal domain (CTD, residues 146-231) of the HIV-1 capsid (CA) protein plays an important role in the CA-CA dimerization and viral assembly of the human immunodeficiency virus type 1. Disrupting the native conformation of the CA is essential for blocking viral capsid formation and viral replication. Thu...


    pub_type: 杂志文章


    authors: Yu X,Wang Q,Yang JC,Buch I,Tsai CJ,Ma B,Cheng SZ,Nussinov R,Zheng J

    更新日期:2009-02-09 00:00:00

  • Transiently Responsive Block Copolymer Micelles Based on N-(2-Hydroxypropyl)methacrylamide Engineered with Hydrolyzable Ethylcarbonate Side Chains.

    abstract::The lack of selectivity and low solubility of many chemotherapeutics impels the development of different biocompatible nanosized drug carriers. Amphiphilic block copolymers, composed of a hydrophilic and hydrophobic domain, show great potential because of their small size, large solubilizing power and loading capacity...


    pub_type: 杂志文章


    authors: Kasmi S,Louage B,Nuhn L,Van Driessche A,Van Deun J,Karalic I,Risseeuw M,Van Calenbergh S,Hoogenboom R,De Rycke R,De Wever O,Hennink WE,De Geest BG

    更新日期:2016-01-11 00:00:00

  • Multifunctional nanoparticles improve therapeutic effect for breast cancer by simultaneously antagonizing multiple mechanisms of multidrug resistance.

    abstract::For efficient reversal of multidrug resistance (MDR) in chemotherapy for breast cancer, multifunctional self-assembled nanoparticles (MSN) based on a new amphiphilic copolymer consisting of bioreducible poly[bis(2-hydroxylethyl)-disulfide-diacrylate-β-tetraethylenepentamine] and polycaprolactone (PBD-PCL) were constru...


    pub_type: 杂志文章


    authors: Yin Q,Shen J,Zhang Z,Yu H,Chen L,Gu W,Li Y

    更新日期:2013-07-08 00:00:00

  • Conformational study of silk-like peptides containing the calcium-binding sequence from calbindin D9k using 13C CP/MAS NMR spectroscopy.

    abstract::The calcium-binding sites of calbindin D(9k) have a helix-loop-helix motif. In this study, the helix motifs were replaced by several Ala-Gly repeating regions designed on the basis of the primary sequences of several silk fibroins. The synthesized peptides were treated with several organic solvents to modify the secon...


    pub_type: 杂志文章


    authors: Asakura T,Hamada M,Nakazawa Y,Ha SW,Knight DP

    更新日期:2006-02-01 00:00:00