Abstract:
OBJECTIVE:To investigate the effect of a combination of botulinum toxin A (BTX-A) and rehabilitation on spasticity, pain and motor functioning in children with acquired brain injury (ABI). METHODS:All children and adolescents with ABI, aged 2-20 years, consecutively treated in the department over a 22-month period, were prospectively followed-up and clinically assessed pre- and post-treatment. They had spasticity and/or dystonia leading to impairment in activities of daily living, orthopaedic deformations and/or pain. Injections were performed using electro-stimulation. Doses of BTX-A (Botox) were administered using recent recommendations. RESULTS:Twenty-five children (mean age 6.3 years) participated in the study (51 injection sessions). All patients received BTX-A injections, followed with physical and/or occupational therapy. Significant improvement was achieved for spasticity reduction (p < 0.0001), command on antagonist muscles (p = 0.03 for the tibialis anterior) and goniometry assessment (p < 0.05). Pain relief was achieved in patients in a minimally responsive state. Functional goals were achieved, such as improving transfers or gait, grasping and releasing abilities, with significant transfer in activities of daily living (p < 0.0001). CONCLUSION:A combination of BTX-A injection with rehabilitation is an interesting option for treatment of muscle tone disorders in children with ABI.
journal_name
Dev Neurorehabiljournal_title
Developmental neurorehabilitationauthors
Guettard E,Roze E,Abada G,Lemesle C,Vidailhet M,Laurent-Vannier A,Chevignard MPdoi
10.1080/17518420902927994subject
Has Abstractpub_date
2009-06-01 00:00:00pages
128-38issue
3eissn
1751-8423issn
1751-8431pii
911666341journal_volume
12pub_type
临床试验,杂志文章abstract:OBJECTIVE:To determine the effect of the changing fifth edition of the Diagnostic and Statistical Manual (DSM-5) criteria on the developmental profiles of children diagnosed with an Autism spectrum disorder (ASD). METHODS:This study examines the effect of DSM-5 changes on impairment profiles of a population of 2054 at...
journal_title:Developmental neurorehabilitation
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abstract:OBJECTIVE:This paper contributes to research investigating the effectiveness of video game intervention in shower training of children with autism spectrum disorders. Previous studies have supported the use of video games in special education. METHODS:We employed the Kinect sensor to gamify shower training. Specifical...
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pub_type: 临床试验,杂志文章
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更新日期:2009-04-01 00:00:00
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journal_title:Developmental neurorehabilitation
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pub_type: 杂志文章,评审
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更新日期:2014-04-01 00:00:00
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