Abstract:
:The ICP34.5 gene from HSV-2 strain 333 was cloned and, when expressed in Vero cells, enhanced the efficiency and extent of glycoprotein processing of glycoprotein C (gC1), a representative viral glycoprotein, during infection with HSV-1 SP7. The ICP34.5 from HSV-1 SP7 limits the extent and efficiency of viral glycoprotein processing. The ability of the HSV-2 ICP34.5 protein to enhance the efficiency and extent of HSV-1 SP7 glycoprotein processing indicates that modulation of viral glycoprotein processing is also a property of the HSV-2 ICP34.5 protein.
journal_name
Arch Viroljournal_title
Archives of virologyauthors
Chatterjee S,Wang JW,Cismowski MJ,Bower JR,Rosenthal KSdoi
10.1007/s00705-009-0341-9subject
Has Abstractpub_date
2009-01-01 00:00:00pages
661-3issue
4eissn
0304-8608issn
1432-8798journal_volume
154pub_type
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