Abstract：
:Some of the properties of three continuous cell lines derived from BK virus-induced hamster tumors were examined. The cell lines had in vitro growth characteristics of transformed cells. Morphologically most of the cells were fibroblastic, but multinucleated giant cells were also common. Ultrastructurally all three cell lines displayed the usual features of cells grown in vitro. Marked variation in the nuclear size and shape as well as prominent nucleoli were characteristic to these cells. No viruses or virus-like particles were found. Virus isolation attempts by fusing the cells with Vero cells were negative, and no virion antigen was detected in these cells by immunofluorescence. T antigen similar to that of other papovaviruses was found in the cells. This antigen stained with sera from a number of hamsters carrying transplanted BK virus-induced tumors, and also with SV 40 T antisera. The antigen disappeared after 30 minutes at 56 degrees C. Cytogenetic analyses showed that the three cell lines were heteroploid with subtetraploid numbers of chromosomes. Chromosome abnormalities were also seen. All three cell lines induced sarcomatous tumors in adult hamsters after subcutaneous inoculation.
journal_name
Arch Viroljournal_title
Archives of virologyauthors
Sten M,Tolonen A,Pitko VM,Nevalainen T,Mäntyjärvi RAdoi
10.1007/BF01318002subject
Has Abstractpub_date
1976-01-01 00:00:00pages
73-82issue
1-2eissn
0304-8608issn
1432-8798journal_volume
50pub_type
杂志文章abstract：:The structure and organization of the large (L) RNA of iris yellow spot virus (IYSV) was determined, and with this report, the complete genomic sequence of IYSV of the genus Tospovirus, family Bunyaviridae has been elucidated. The L RNA of IYSV was 8,880 nucleotides in length and contained a single open reading frame ...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s00705-009-0568-5
更新日期：2010-02-01 00:00:00
abstract：:The porcine paramyxovirus LPM recognizes alpha, but not beta, anomers of sialic acid containing structures, specifically sialyl (alpha 2,3) lactose. The virus specificity is directed to the sialyl residue and to the C'4 axial OH and the C'6 CH2OH of the galactose present in this structure. ...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/BF01309755
更新日期：1993-01-01 00:00:00
abstract：:Poultry production is an important sector of agriculture in Sri Lanka; however, there is a lack of information regarding circulation of infectious bronchitis virus (IBV). RNA was extracted from chicken tissues, subjected to IBV S1 RT-PCR, and sequenced. Overall, 19 out of 34 (55.88 %) samples were IBV positive and con...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s00705-016-2831-x
更新日期：2016-06-01 00:00:00
abstract：:Our previous studies demonstrated that hepatitis E virus (HEV) requires the multivesicular body (MVB) pathway to release virus particles, suggesting that HEV utilizes the cellular ESCRT machinery in the cytoplasm, not at the cell surface, to be released from infected cells. In this study, we generated a murine monoclo...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s00705-013-1912-3
更新日期：2014-05-01 00:00:00
abstract：:The complete nucleotide sequence of the RNA genome of turnip mosaic virus Japanese strain (TuMV-J) has been determined from five overlapping cDNA clones and by direct sequencing of viral RNA. The RNA sequence was 9833 nucleotides in length, excluding a 3' terminal poly(A) tail. An AUG triplet at position 130-132 was a...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/BF01718209
更新日期：1996-01-01 00:00:00
abstract：:Human bocavirus (HBoV) is a new parvovirus associated with acute respiratory tract infection (ARTI). In order to evaluate HBoV significance as an agent of acute respiratory disease, we screened 1,135 respiratory samples from children and adults with and without symptoms during two complete calendar years. HBoV1 preval...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s00705-014-2238-5
更新日期：2015-01-01 00:00:00
abstract：:In February 2008, five patients were infected with the H1N1 subtype of influenza A virus in one hospital ward for immunocompromised patients at a hospital in North Rhine-Westphalia, Germany. All of these patients had an established haematologic disease and tested positive either for viral RNA or antigen shortly after ...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s00705-010-0771-4
更新日期：2010-11-01 00:00:00
abstract：:In guinea-pig infected with foot-and-mouth disease virus (FMDV), Langerhans cells in the foot pads increase in number and show viral antigens 24 hours post-inoculation, preceding appearance of virus in epithelial cells and vesiculation. This observation suggests that Langerhans cells may be engaged in virus transport ...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/BF01309929
更新日期：1985-01-01 00:00:00
abstract：:Genetic heterogeneous mouse populations selected for high (HIII) and low (LIII) antibody response were used to study some aspects of mouse hepatitis virus 3 (MHV3) infection, such as the resistance pattern, virus replication in the liver and peritoneal exudate or in cultured peritoneal macrophages, the interferon (IFN...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/BF01309475
更新日期：1994-01-01 00:00:00
abstract：:A reversed passive hemagglutination (RPHA) method was developed for the detection of bovine coronavirus in fecal specimens. Sheep erythrocytes fixed with glutaraldehyde, and then treated with tannic acid were coated with anti-bovine coronavirus rabbit antibodies purified by affinity chromatography using bovine coronav...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/BF01315291
更新日期：1984-01-01 00:00:00
abstract：:Human papilloma virus DNA has been examined for heterogeneity by electron microscopy, reassociation kinetics, and restriction endonuclease digestion. No heterogeneity in contour length was detected. The reassociation rate of papilloma DNA isolated from pooled warts was consistent with that expected for a homogeneous, ...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/BF01314794
更新日期：1977-01-01 00:00:00
abstract：:The viral reverse transcriptase gene was amplified from the plasma of 27 drug-naïve and five drug-experienced HIV patients in Northern India. Follow-up samples of naïve patients after antiretroviral therapy initiation were collected in six patients at 3 months and three patients at 6 months. Phylogenetic analysis reve...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s00705-010-0605-4
更新日期：2010-04-01 00:00:00
abstract：:The revised International Code of Virus Classification and Nomenclature [7] followed by the Seventh Report of the International Committee on Taxonomy of Viruses (ICTV) [9] have generated a lot of criticism [2,4-6]. The main causes of criticism are (i) use of monomials instead of non-latinized binomials, as has been pr...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s007050200051
更新日期：2002-11-01 00:00:00
abstract：:The IL28B gene is associated with spontaneous or treatment-induced HCV viral clearance. However, the mechanism by which the IL28B single nucleotide polymorphism (SNP) affects the extra-hepatic HCV immune responses and its relationship to HCV pathogenesis have not been thoroughly investigated. To examine the mechanism ...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s00705-016-3015-4
更新日期：2016-11-01 00:00:00
abstract：:Complete nucleotide sequences of three strains (I, III, and IV) of Barley yellow mosaic virus (BaYMV) isolated in Japan were determined. The length of the genome was the same among the three strains; RNA1 was 7,642 nt and RNA2 was 3,585 nt. The molecular phylogenetic analysis showed that strain I was most closely rela...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s00705-008-0163-1
更新日期：2008-01-01 00:00:00
abstract：:A total of 72 Borna Disease virus infected rabbits were treated with different concentrations of cyclophosphamide, glucocorticoids or both in combination. Comparison with untreated, infected rabbits showed a drastic alteration in the clinical picture, a considerable prolongation of the survival time, and differences i...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/BF01318132
更新日期：1981-01-01 00:00:00
abstract：:Chronic hepatitis C virus (HCV) infection often leads to liver cancer. The HCV NS2 protein is a hydrophobic transmembrane protein that associates with several cellular proteins in mammalian cells. In this report, we investigated the function of NS2 protein on HCV replication and translation by using a transient cell-b...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s00705-008-0198-3
更新日期：2008-01-01 00:00:00
abstract：:The stability of regions containing tandemly reiterated sequences in the S component of the herpes simplex virus type 1 (HSV-1) genome was determined, by comparing restriction fragments of the regions among sets of HSV-1 isolates derived from a single source. The 6 reiterations examined were grouped into three. Reiter...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/BF01313958
更新日期：1989-01-01 00:00:00
abstract：:Betanodaviruses, members of the family Nodaviridae, have small positive-stranded bipartite RNA genomes and are the causal agent of viral nervous necrosis (VNN) in many species of marine farmed fish. In the aquaculture industry, outbreaks of betanodavirus infection and spread in larval and juvenile fish result in devas...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s00705-007-1061-7
更新日期：2007-01-01 00:00:00
abstract：:The rate of evolution of the human papillomavirus 16 (HPV16) genome is low. However, the ability of the E6 oncoprotein to interact with distinct p53 variants causes selective pressure on the E6 gene. In addition, intratypic recombination events in the HPV16 E6 and E7 genes have been characterized as extraordinary phen...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s00705-012-1555-9
更新日期：2013-04-01 00:00:00
abstract：:Pseudocowpox is a zoonosis caused by pseudocowpox virus (PCPV), which mainly affects cows but can be an occupational disease of humans. The aim of the study was to validate a quantitative polymerase chain reaction (qPCR) assay for the detection of PCPV. The assay was able to detect up to 1000 copies of PCPV per µL in ...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s00705-020-04872-4
更新日期：2021-01-01 00:00:00
abstract：:A collection of 148 adenovirus strains of subgenus C collected in Argentina, Chile, and Uruguay were studied by restriction enzyme analysis of genomic DNA with endonucleases BamHI, BglII, BstEII, EcoRI, HindIII, KpnI, and SmaI. Only strains corresponding to serotypes 1, 2, and 5 were identified representing both alrea...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/BF01309841
更新日期：1993-01-01 00:00:00
abstract：:Bacteriophage JBP901, isolated from fermented food, is specific for Bacillus cereus group species and exhibits a broad host spectrum among a large number of B. cereus isolates. Genome sequence analysis revealed a linear 159,492-bp genome with overall G+C content of 39.7 mol%, and 201 ORFs. The presence of a putative m...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s00705-015-2485-0
更新日期：2015-09-01 00:00:00
abstract：:Cowpea and broad bean plants showing severe stunting and leaf rolling symptoms were observed in Hefei city, Anhui province, China, in 2014. Symptomatic plants from both species were shown to be infected with milk vetch dwarf virus (MDV) by PCR. The complete genomes of MDV isolates from cowpea and broad bean were seque...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s00705-017-3348-7
更新日期：2017-08-01 00:00:00
abstract：:Scutellaria baicalensis Georgi, a Chinese herbal decoction, has been used for the treatment of the common cold, fever and influenza virus infections. In previous studies, we found that oral administration of baicalein resulted in the inhibition of influenza A virus replication in vivo, which was linked to baicalin in ...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s00705-014-2192-2
更新日期：2014-12-01 00:00:00
abstract：:Simian varicella virus (SVV) infection of non-human primates is used as a model to study the pathogenesis and latency of varicella-zoster virus (VZV), the etiological agent of chickenpox and shingles. Uracil DNA glycosylase (UDG) is a DNA repair enzyme responsible for excision of uracil residues misincorporated into D...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s007050050630
更新日期：1999-01-01 00:00:00
abstract：:Chilli veinal mottle virus (ChiVMV) is an important plant pathogen with a wide host range. The genetic structure of ChiVMV was investigated by analyzing the coat protein (CP) genes of 87 ChiVMV isolates from seven Asian regions. Pairwise F ST values between ChiVMV populations ranged from 0.108 to 0.681, indicating a s...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s00705-016-2761-7
更新日期：2016-05-01 00:00:00
abstract：:Influenza C viruses did not possess neuraminidase activity when examined using either fetuin or sialyllactose as substrate. Purified preparations of influenza C virus inhibited hemagglutination by NWS hemagglutinin. The hemagglutination inhibiting activity was abolished by treatment of influenza C virus with neuramini...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/BF01320578
更新日期：1976-01-01 00:00:00
abstract：:Use of Urografin and Conray for the equilibrium centrifugation of viruses is described. These pharmaceuticals, which consist of iodinated arylic compounds, reach densities of 1.6 g/cm3 and have low intrinsic viscosities. Poliovirus, Newcastle disease virus, and lymphocytic choriomeningitis virus were centrifuged to eq...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/BF01318245
更新日期：1975-01-01 00:00:00
abstract：:The genome of a Spanish isolate of Broad bean wilt virus-1 (BBWV-1) was completely sequenced and compared with available sequences of other isolates of the genus Fabavirus (BBWV-1 and BBWV-2). This consisted of two RNAs of 5814 and 3431 nucleotides, respectively, and their organization was similar to that of other mem...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s00705-005-0582-1
更新日期：2005-10-01 00:00:00
