Synthesis and characterization of cell-adhesive silk-like proteins constructed from the sequences of Anaphe silk fibroin and fibronectin.

abstract：:Polyrotaxanes, a family of rod-shaped nanomaterials comprised of noncovalent polymer/macrocycle assemblies, are being used in a growing number of materials and biomedical applications. Their physiochemical properties can vary widely as a function of composition, potentially leading to different in vivo performance out...

journal_title：Biomacromolecules

authors： Collins CJ,Mondjinou Y,Loren B,Torregrosa-Allen S,Simmons CJ,Elzey BD,Ayat N,Lu ZR,Thompson D

更新日期：2016-09-12 00:00:00

abstract：:Novel biodegradable poly(carbonate ester)s with photolabile protecting groups were synthesized by ring-opening copolymerization of L-lactide (LA) with 5-methyl-5-(2-nitro-benzoxycarbonyl)-1,3-dioxan-2-one (MNC) with diethyl zinc (Et2Zn) as catalyst. The poly(L-lactide-co-5-methyl-5-carboxyl-1,3-dioxan-2-one) (P(LA-co-...

journal_title：Biomacromolecules

authors： Xie Z,Hu X,Chen X,Sun J,Shi Q,Jing X

更新日期：2008-01-01 00:00:00

abstract：:Poly(L-lactide) (PLLA) with various alkyl ester chain end groups were synthesized by ring-opening polymerization of L-lactide in the presence of zinc alkoxide as a catalyst. The structural effect of chain end groups on the rate of enzymatic and nonenzymatic degradations for amorphous films of PLLA were investigated at...

journal_title：Biomacromolecules

authors： Kurokawa K,Yamashita K,Doi Y,Abe H

更新日期：2008-03-01 00:00:00

abstract：:Enhancing the molecular orientation of the regenerated silk fibroin (RF) up to a level comparable to the native silk is highly challenging. Our novel and promising strategy for the poststretching process is (1) creating at first an α-helix-HFIP complex with a hexagonal packing as an intermediate state and then (2) str...

journal_title：Biomacromolecules

authors： Yoshioka T,Tashiro K,Ohta N

更新日期：2016-04-11 00:00:00

abstract：:Electrically conductive hydrogel composites consisting of oligo(polyethylene glycol) fumarate (OPF) and polypyrrole (PPy) were developed for applications in nerve regeneration. OPF-PPy scaffolds were synthesized using three different anions: naphthalene-2-sulfonic acid sodium salt (NSA), dodecylbenzenesulfonic acid so...

journal_title：Biomacromolecules

authors： Runge MB,Dadsetan M,Baltrusaitis J,Ruesink T,Lu L,Windebank AJ,Yaszemski MJ

更新日期：2010-11-08 00:00:00

abstract：:Surface modification of biodegradable vascular grafts is an important strategy to improve the in situ endothelialization of tissue engineered vascular grafts (TEVGs) and prevent major complications associated with current synthetic grafts. Important strategies for improving endothelialization include increasing endoth...

journal_title：Biomacromolecules

authors： Melchiorri AJ,Hibino N,Yi T,Lee YU,Sugiura T,Tara S,Shinoka T,Breuer C,Fisher JP

更新日期：2015-02-09 00:00:00

abstract：:Inulin, the polydisperse polyfructose, extracted from chicory, has been modified via transesterification, using fatty acid methyl esters (FAME). The grafting of an alkyl chain onto the inulin backbone under different conditions for the development of potential tensio-active derivatives is described. The modification o...

journal_title：Biomacromolecules

authors： Rogge TM,Stevens CV

更新日期：2004-09-01 00:00:00

abstract：:Thermoresponsive polymers with lower critical solution temperatures (LCSTs) are of significant interest for a wide range of applications from sensors to drug delivery vehicles. However, the most widely investigated LCST polymers have nondegradable backbones, limiting their applications in vivo or in the environment. D...

journal_title：Biomacromolecules

authors： Rabiee Kenaree A,Sirianni QEA,Classen K,Gillies ER

更新日期：2020-09-14 00:00:00

abstract：:New types of hydrogels have been obtained starting from high bloom purified gelatin A, alone or in mixtures with hyaluronan and with a hyaluronan derivative bearing primary amino groups, by transglutaminase-catalyzed cross-linking. The reticulation process, carried out adopting two different temperature protocols, and...

journal_title：Biomacromolecules

authors： Crescenzi V,Francescangeli A,Taglienti A

更新日期：2002-11-01 00:00:00

abstract：:Peak force infrared (PFIR) microscopy is a recently developed approach to acquire multiple chemical and physical material properties simultaneously and with nanometer resolution: topographical features, infrared (IR)-sensitive maps, adhesion, stiffness, and locally resolved IR spectra. This multifunctional mapping is ...

journal_title：Biomacromolecules

authors： Gusenbauer C,Jakob DS,Xu XG,Vezenov DV,Cabane É,Konnerth J

更新日期：2020-10-12 00:00:00

abstract：:We investigated the rheological properties and the penetration of differently sized carboxylated nanoparticles in pig pulmonary mucus, on different distance and time scales. Nanoparticles were either mechanically mixed into the mucus samples or deposited as an aerosol, the latter resembling a more physiologically rele...

journal_title：Biomacromolecules

authors： Murgia X,Pawelzyk P,Schaefer UF,Wagner C,Willenbacher N,Lehr CM

更新日期：2016-04-11 00:00:00

abstract：:Horseradish peroxidase-catalyzed polymerization of cardanol in aqueous organic solvent was investigated in the presence of a redox mediator. Cardanol is a phenol derivative from a renewable resource mainly having a C15 unsaturated hydrocarbon chain with mostly 1-3 double bonds at a meta position. Unlike soybean peroxi...

journal_title：Biomacromolecules

authors： Won K,Kim YH,An ES,Lee YS,Song BK

更新日期：2004-01-01 00:00:00

abstract：:We have constructed a tandem gene expression cassette containing three Ralstonia eutropha poly[(R)-3-hydroxybutyrate] (PHB) synthesis genes under the control of the Pichia pastoris glyceraldehyde-3-phosphate promoter and the green fluorescent protein (Gfp) under the control of the P. pastoris alcohol oxidase promoter....

journal_title：Biomacromolecules

authors： Vijayasankaran N,Carlson R,Srienc F

更新日期：2005-03-01 00:00:00

abstract：:Subunit vaccines can have excellent safety profiles, but their ability to give rise to robust immune responses is often compromised. For glycan-based vaccines, insufficient understanding of B and T cell epitope combinations that yield optimal immune activation hinders optimization. To determine which antigen features ...

journal_title：Biomacromolecules

authors： Bennett NR,Jarvis CM,Alam MM,Zwick DB,Olson JM,Nguyen HV,Johnson JA,Cook ME,Kiessling LL

更新日期：2019-12-09 00:00:00

abstract：:We report a facile method of generating ultradense poly(l-lysine)-graft-poly(ethylene glycol) (PLL-g-PEG) surface by using high temperature alone, which in turn provides dramatic improvement in resisting nonspecific bioadsorption. X-ray photoelectron spectroscopy (XPS) revealed that the surface graft density increased...

journal_title：Biomacromolecules

authors： Ogaki R,Zoffmann Andersen O,Jensen GV,Kolind K,Kraft DC,Pedersen JS,Foss M

更新日期：2012-11-12 00:00:00

abstract：:Properties of Aloe vera galacturonate hydrogels formed via Ca(2+) crosslinking have been studied in regard to key parameters influencing gel formation including molecular weight, ionic strength, and molar ratio of Ca(2+) to COO(-) functionality. Dynamic oscillatory rheology and pulsed field gradient NMR (PFG-NMR) stud...

journal_title：Biomacromolecules

authors： McConaughy SD,Kirkland SE,Treat NJ,Stroud PA,McCormick CL

更新日期：2008-11-01 00:00:00

abstract：:The encapsulation of live cells with polymeric coat-ings is a versatile approach to modulate or control the response cells to their environment. The layer-by-layer (LbL) self-assembly of nonimmunogenic polyelectrolytes is employed here to attenuate or suppress the binding of antibodies to live red blood cells (RBCs) a...

journal_title：Biomacromolecules

authors： Mansouri S,Merhi Y,Winnik FM,Tabrizian M

更新日期：2011-03-14 00:00:00

abstract：:The clinical application of holmium-loaded poly(L-lactic acid) (PLLA) microspheres for the radionuclide treatment of liver malignancies requires in depth understanding of the degradation characteristics of the microspheres. To this end, an in-vitro degradation study was conducted. PLLA-microspheres with and without Ho...

journal_title：Biomacromolecules

authors： Zielhuis SW,Nijsen JF,Krijger GC,van het Schip AD,Hennink WE

更新日期：2006-07-01 00:00:00

abstract：:l-Proline is the only, out of 20 essential, amino acid that contains a cyclized substituted α-amino group (is formally an imino acid), which restricts its conformational shape. The synthesis of well-defined homo- and copolymers of l-proline has been plagued either by the low purity of the monomer or the inability of m...

journal_title：Biomacromolecules

authors： Gkikas M,Iatrou H,Thomaidis NS,Alexandridis P,Hadjichristidis N

更新日期：2011-06-13 00:00:00

abstract：:Receptor-mediated, cell-specific delivery of siRNA enables silencing of target genes in specific tissues, opening the door to powerful therapeutic options for a multitude of diseases. However, the development of delivery systems capable of targeted and effective siRNA delivery typically requires multiple steps and the...

journal_title：Biomacromolecules

authors： Benoit DS,Srinivasan S,Shubin AD,Stayton PS

更新日期：2011-07-11 00:00:00

abstract：:This paper describes the synthesis and evaluation of a series of multifunctional poly-l-glutamic acid derivatives that can be used as vectors for gene delivery. They readily form polyelectrolyte complexes with DNA, resulting in a reduced surface charge and size of the DNA. The formation of a polymer-DNA complex and th...

journal_title：Biomacromolecules

authors： Dubruel P,Dekie L,Schacht E

更新日期：2003-09-01 00:00:00

abstract：:Enzymatic adsorption and degradation of three types of aliphatic polyester films and two types of polyolefin films by the extracellular PHB depolymerase from Alcaligenes faecalis T1 have been studied by using a quartz crystal microbalance (QCM) technique. Hydrolysis of poly[(R)-3-hydroxybutyrate] was quantitatively fo...

journal_title：Biomacromolecules

authors： Yamashita K,Aoyagi Y,Abe H,Doi Y

更新日期：2001-04-01 00:00:00

abstract：:This paper describes the synthesis and characterization of polymer-peptide conjugates to be used as infection-resistant coating for biomaterial implants and devices. Antiadhesive polymer brushes composed of block copolymer Pluronic F-127 (PF127) were functionalized with antimicrobial peptides (AMP), able to kill bacte...

journal_title：Biomacromolecules

authors： Muszanska AK,Rochford ET,Gruszka A,Bastian AA,Busscher HJ,Norde W,van der Mei HC,Herrmann A

更新日期：2014-06-09 00:00:00

abstract：:The dynamics of silk protein in the presence and absence of water has been investigated by dielectric relaxation spectroscopy (DRS). The silk fibroin film cast from its water solution contains 4-7 wt % bound water molecules, which can be removed by dehydration at 165 °C. Temperature and frequency scans were performed ...

journal_title：Biomacromolecules

authors： Yu L,Hu X,Kaplan D,Cebe P

更新日期：2010-10-11 00:00:00

abstract：:Protein-based polymers are increasingly being used in biomaterial applications because of their ease of customization and potential monodispersity. These advantages make protein polymers excellent candidates for bioanalytical applications. Here we describe improved methods for producing drag-tags for free-solution con...

journal_title：Biomacromolecules

authors： Lin JS,Albrecht JC,Meagher RJ,Wang X,Barron AE

更新日期：2011-06-13 00:00:00

abstract：:There is compelling evidence that, beyond their traditional role in hemostasis and thrombosis, platelets play a significant role in mediating hematologic mechanisms of tumor metastasis by directly and indirectly interacting with pro-metastatic cancer cells. With this rationale, we hypothesized that platelets can be an...

journal_title：Biomacromolecules

authors： Modery-Pawlowski CL,Master AM,Pan V,Howard GP,Sen Gupta A

更新日期：2013-03-11 00:00:00

abstract：:A recombinant silk-elastin-like protein copolymer SELP-47K containing tandemly repeated amino acid sequence blocks from silk, GAGAGS, and elastin, GVGVP, was fabricated into microdiameter fibers using a wet-spinning technique. Raman spectral analysis revealed the formation of antiparallel beta-sheet crystals of the si...

journal_title：Biomacromolecules

authors： Qiu W,Teng W,Cappello J,Wu X

更新日期：2009-03-09 00:00:00

abstract：:Hydrogels are able to mimic the basic three-dimensional (3D) biological, chemical, and mechanical properties of native tissues. Since hyaluronic acid (HA) is a chief component of human extracellular matrix (ECM), it represents an extremely attractive starting material for the fabrication of scaffolds for tissue engine...

journal_title：Biomacromolecules

authors： Kufelt O,El-Tamer A,Sehring C,Schlie-Wolter S,Chichkov BN

更新日期：2014-02-10 00:00:00

abstract：:The morphologies of several ionotropic alginate hydrogels and aerogels were investigated by SAXS according to the nature of the divalent metal cation (Mn(2+), Co(2+), Zn(2+), Cu(2+)) and the guluronic fraction of the alginate. All alginate hydrogel and aerogel samples show isotropic small-angle X-ray scattering. Gelat...

journal_title：Biomacromolecules

authors： Agulhon P,Robitzer M,David L,Quignard F

更新日期：2012-01-09 00:00:00

abstract：:Hierarchical nanocomposite films with Pd-PdO nanoparticles anchored uniformly on the inner surface of TiO2 nanotubes were achieved through a stepwise bioredox/artificial oxygenation approach by using the natural eggshell membrane (ESM) as a template. The Pd content ratio of Pd-PdO loading could be arbitrarily varied f...

journal_title：Biomacromolecules

authors： Su H,Dong Q,Han J,Zhang D,Guo Q

更新日期：2008-02-01 00:00:00