The serum complement system: a simplified laboratory exercise to measure the activity of an important component of the immune system.

Abstract:

:The immune system is a vital physiological component that affords animals protection from disease and is composed of innate and adaptive mechanisms that rely on cellular and dissolved components. The serum complement system is a series of dissolved proteins that protect against a variety of pathogens. The activity of complement in serum can be determined by its ability to lyse red blood cells in vitro. Here, we describe a modification of a standard complement hemolysis assay that makes an interesting and informative laboratory exercise suitable for a variety of courses including physiology.

journal_name

Adv Physiol Educ

authors

Inglis JE,Radziwon KA,Maniero GD

doi

10.1152/advan.00061.2007

subject

Has Abstract

pub_date

2008-12-01 00:00:00

pages

317-21

issue

4

eissn

1043-4046

issn

1522-1229

pii

32/4/317

journal_volume

32

pub_type

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