Abstract:
:Basic cardiac electrophysiology is foundational to understanding normal cardiac function in terms of rate and rhythm and initiation of cardiac muscle contraction. The primary clinical tool for assessing cardiac electrical events is the electrocardiogram (ECG), which provides global and regional information on rate, rhythm, and electrical conduction as well as changes in electrical activity associated with cardiac disease, particularly ischemic heart disease. This teaching review is written at a level appropriate for first- and second-year medical students. Specific concepts discussed include ion equilibrium potentials, electrochemical forces driving ion movements across membranes, the role of ion channels in determining membrane resting potentials and action potentials, and the conduction of action potentials within the heart. The electrophysiological basis for the ECG is then described, followed by discussion on how ischemia alters cellular electrophysiology and ECG recordings, with particular emphasis on changes in T waves and ST segments of the ECG.
journal_name
Adv Physiol Educjournal_title
Advances in physiology educationauthors
Klabunde REdoi
10.1152/advan.00105.2016subject
Has Abstractpub_date
2017-03-01 00:00:00pages
29-37issue
1eissn
1043-4046issn
1522-1229pii
41/1/29journal_volume
41pub_type
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journal_title:Advances in physiology education
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journal_title:Advances in physiology education
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journal_title:Advances in physiology education
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