当前位置： SCI文献检索 > PSYCHONEUROENDOCRINOLOGY期刊下所有文献 > Sex steroids and brain structure in pubertal boys and girls.

Sex steroids and brain structure in pubertal boys and girls.

Abstract：

:Sex steroids exert important organizational effects on brain structure. Early in life, they are involved in brain sexual differentiation. During puberty, sex steroid levels increase considerably. However, to which extent sex steroid production is involved in structural brain development during human puberty remains unknown. The relationship between pubertal rises in testosterone and estradiol levels and brain structure was assessed in 37 boys and 41 girls (10-15 years). Global brain volumes were measured using volumetric-MRI. Regional gray and white matter were quantified with voxel-based morphometry (VBM), a technique which measures relative concentrations ('density') of gray and white matter after individual global differences in size and shape of brains have been removed. Results showed that, corrected for age, global gray matter volume was negatively associated with estradiol levels in girls, and positively with testosterone levels in boys. Regionally, a higher estradiol level in girls was associated with decreases within prefrontal, parietal and middle temporal areas (corrected for age), and with increases in middle frontal-, inferior temporal- and middle occipital gyri. In boys, estradiol and testosterone levels were not related to regional brain structures, nor were testosterone levels in girls. Pubertal sex steroid levels could not explain regional sex differences in regional gray matter density. Boys were significantly younger than girls, which may explain part of the results. In conclusion, in girls, with the progression of puberty, gray matter development is at least in part directly associated with increased levels of estradiol, whereas in boys, who are in a less advanced pubertal stage, such steroid-related development could not (yet) be found. We suggest that in pubertal girls, estradiol may be implicated in neuronal changes in the cerebral cortex during this important period of brain development.

journal_name

Psychoneuroendocrinology

journal_title

Psychoneuroendocrinology

authors

Peper JS,Brouwer RM,Schnack HG,van Baal GC,van Leeuwen M,van den Berg SM,Delemarre-Van de Waal HA,Boomsma DI,Kahn RS,Hulshoff Pol HE

doi

10.1016/j.psyneuen.2008.09.012

subject

Has Abstract

pub_date

2009-04-01 00:00:00

pages

332-42

issue

3

eissn

0306-4530

issn

1873-3360

pii

S0306-4530(08)00253-9

journal_volume

34

pub_type

杂志文章

相关文献

PSYCHONEUROENDOCRINOLOGY文献大全
  • N-terminal pro-atrial natriuretic peptide response to acute exercise in depressed patients and healthy controls.

    abstract：BACKGROUND:The dysfunction of hypothalamic-pituitary-adrenal (HPA) axis in major depression includes hyperactivity and reduced feedback inhibition. Atrial natriuretic peptide (ANP) is able to reduce the HPA-axis response to stress and has an anxiolytic effect in rodents and humans. We hypothesized that patients with de...

    journal_title：Psychoneuroendocrinology

    pub_type： 杂志文章,随机对照试验

    doi：10.1016/j.psyneuen.2010.09.009

    authors： Krogh J,Ströhle A,Westrin A,Klausen T,Jørgensen MB,Nordentoft M

    更新日期：2011-06-01 00:00:00

  • The gut microbiota metabolite indole increases emotional responses and adrenal medulla activity in chronically stressed male mice.

    abstract：BACKGROUND AND AIMS:The gut microbiota produces metabolites that are an integral part of the metabolome and, as such, of the host physiology. Changes in gut microbiota metabolism could therefore contribute to pathophysiological processes. We showed previously that a chronic and moderate overproduction of indole from tr...

    journal_title：Psychoneuroendocrinology

    pub_type： 杂志文章

    doi：10.1016/j.psyneuen.2020.104750

    authors： Mir HD,Milman A,Monnoye M,Douard V,Philippe C,Aubert A,Castanon N,Vancassel S,Guérineau NC,Naudon L,Rabot S

    更新日期：2020-09-01 00:00:00

  • Blunted basal corticosterone pulsatility predicts post-exposure susceptibility to PTSD phenotype in rats.

    abstract：:The basal activity of the hypothalamic-pituitary-adrenal axis is highly dynamic and is characterized by both circadian and ultradian (pulsatile) patterns of hormone secretion. Pulsatility of glucocorticoids has been determined to be critical for optimal transcriptional, neuroendocrine, and behavioral responses. We use...

    journal_title：Psychoneuroendocrinology

    pub_type： 杂志文章

    doi：10.1016/j.psyneuen.2017.09.023

    authors： Danan D,Matar MA,Kaplan Z,Zohar J,Cohen H

    更新日期：2018-01-01 00:00:00

  • Pressor, norepinephrine, and pituitary responses to two TRH doses in Alzheimer's disease and normal older men.

    abstract：:Changes in blood pressure (BP), plasma norepinephrine (NE), serum prolactin (PRL), luteinizing hormone (LH), and follicle-stimulating hormone (FSH) associated with infusions of two thyrotropin-releasing hormone (TRH) doses (0.1 mg, 0.5 mg) were examined in 10 men with early-onset Alzheimer's disease (AD) and nine norm...

    journal_title：Psychoneuroendocrinology

    pub_type： 杂志文章

    doi：10.1016/0306-4530(89)90033-4

    authors： Lampe TH,Veith RC,Plymate SR,Risse SC,Kopeikin H,Cubberley L,Raskind MA

    更新日期：1989-01-01 00:00:00

  • Low-dose hydrocortisone replacement improves wellbeing and pain tolerance in chronic pain patients with opioid-induced hypocortisolemic responses. A pilot randomized, placebo-controlled trial.

    abstract：UNLABELLED:Long-term opioid therapy has been associated with low cortisol levels due to central suppression of the hypothalamic-pituitary-adrenal axis. The implications of hypocortisolism on wellbeing have not been established. Our aim was to determine whether intervention with physiologic glucocorticoid replacement th...

    journal_title：Psychoneuroendocrinology

    pub_type： 杂志文章,随机对照试验

    doi：10.1016/j.psyneuen.2015.03.015

    authors： Nenke MA,Haylock CL,Rankin W,Inder WJ,Gagliardi L,Eldridge C,Rolan P,Torpy DJ

    更新日期：2015-06-01 00:00:00

  • Septal oxytocin administration impairs peer affiliation via V1a receptors in female meadow voles.

    abstract：:The peptide hormone oxytocin (OT) plays an important role in social behaviors, including social bond formation. In different contexts, however, OT is also associated with aggression, social selectivity, and reduced affiliation. Female meadow voles form social preferences for familiar same-sex peers under short, winter...

    journal_title：Psychoneuroendocrinology

    pub_type： 杂志文章

    doi：10.1016/j.psyneuen.2016.02.025

    authors： Anacker AM,Christensen JD,LaFlamme EM,Grunberg DM,Beery AK

    更新日期：2016-06-01 00:00:00

  • Stress, serotonergic function, and mood in users of oral contraceptives.

    abstract：:The relationship between stress and changes in insulin levels, plasma ratio of tryptophan to other large neutral amino acids (LNAAs), mood, and food intake was investigated in women taking monophasic oral contraceptives containing progestagens. Subjects experiencing high levels of stress displayed significant decrease...

    journal_title：Psychoneuroendocrinology

    pub_type： 临床试验,杂志文章

    doi：10.1016/0306-4530(94)00063-g

    authors： Tuiten A,Panhuysen G,Koppeschaar H,Fekkes D,Pijl H,Frölich M,Krabbe P,Everaerd W

    更新日期：1995-01-01 00:00:00

  • The beneficial effects of strength exercise on hippocampal cell proliferation and apoptotic signaling is impaired by anabolic androgenic steroids.

    abstract：:Previous studies have shown that strength exercise improves memory and increases expression of a myriad of proteins involved on neuronal survival and synaptic plasticity in the hippocampus. Conversely, chronic exposure to supraphysiological levels of anabolic androgenic steroids (AAS) can induce psychiatric abnormalit...

    journal_title：Psychoneuroendocrinology

    pub_type： 杂志文章

    doi：10.1016/j.psyneuen.2014.08.009

    authors： Novaes Gomes FG,Fernandes J,Vannucci Campos D,Cassilhas RC,Viana GM,D'Almeida V,de Moraes Rêgo MK,Buainain PI,Cavalheiro EA,Arida RM

    更新日期：2014-12-01 00:00:00

  • Neonatal overfeeding alters adult anxiety and stress responsiveness.

    abstract：:The neonatal nutritional environment is critical for programming the systems regulating body weight, and an inappropriate nutritional environment in early life can lead to overweight or obesity later on. In this study we demonstrate that changes to the neonatal nutritional environment, induced by changing the litter s...

    journal_title：Psychoneuroendocrinology

    pub_type： 杂志文章

    doi：10.1016/j.psyneuen.2009.02.013

    authors： Spencer SJ,Tilbrook A

    更新日期：2009-09-01 00:00:00

  • Psychoneuroimmunology and immunopsychiatry of zebrafish.

    abstract：:Despite the high prevalence of neural and immune disorders, their etiology and molecular mechanisms remain poorly understood. As the zebrafish (Danio rerio) is increasingly utilized as a powerful model organism in biomedical research, mounting evidence suggests these fish as a useful tool to study neural and immune me...

    journal_title：Psychoneuroendocrinology

    pub_type： 杂志文章,评审

    doi：10.1016/j.psyneuen.2018.03.014

    authors： de Abreu MS,Giacomini ACVV,Zanandrea R,Dos Santos BE,Genario R,de Oliveira GG,Friend AJ,Amstislavskaya TG,Kalueff AV

    更新日期：2018-06-01 00:00:00

  • Endocrinological and psychological responses to job stressors: an experimental test of the job demand--control model.

    abstract：:The buffer hypothesis of the Job Demand-Control Model predicts that high levels of job control compensate for the negative effects of high job demands on well-being and health. Several studies have tested this hypothesis, but the results are far from consistent. The objective of this study was to test the buffer hypot...

    journal_title：Psychoneuroendocrinology

    pub_type： 临床试验,杂志文章

    doi：10.1016/j.psyneuen.2010.12.016

    authors： Häusser JA,Mojzisch A,Schulz-Hardt S

    更新日期：2011-08-01 00:00:00

  • Differential association of somatic and cognitive symptoms of depression and anxiety with inflammation: findings from the Netherlands Study of Depression and Anxiety (NESDA).

    abstract：OBJECTIVE:Depression and anxiety have been suggested to be associated with systemic inflammation upregulation. However, results are not always consistent, which may be due to symptom heterogeneity of depression and anxiety. There are some indications that associations with inflammation are mainly driven by somatic symp...

    journal_title：Psychoneuroendocrinology

    pub_type： 杂志文章,多中心研究

    doi：10.1016/j.psyneuen.2013.01.002

    authors： Duivis HE,Vogelzangs N,Kupper N,de Jonge P,Penninx BW

    更新日期：2013-09-01 00:00:00

  • Increased basal activity of the hypothalamo-pituitary-adrenal axis during pregnancy in rats bred for high anxiety-related behaviour.

    abstract：:In order to test the hypothesis that prenatal hormones influence the emotional maturation of the offspring, the hypothalamo-pituitary-adrenal (HPA) axis activity was studied at the end of pregnancy in two rat breeding lines differing consistently in their innate anxiety-related behaviour in the elevated plus-maze. Vir...

    journal_title：Psychoneuroendocrinology

    pub_type： 杂志文章

    doi：10.1016/s0306-4530(98)00023-7

    authors： Neumann ID,Wigger A,Liebsch G,Holsboer F,Landgraf R

    更新日期：1998-07-01 00:00:00

  • Long term modulation of the HPA axis by the hippocampus. Behavioral, biochemical and immunological endpoints in rats exposed to chronic mild stress.

    abstract：:Mature rats were given lesions of the hippocampus (HIPPO), subiculum (SUBIC) or fimbria-fornix (FIFO) and then received the mild chronic stressors of food deprivation and isolation housing for ten months prior to testing. Group differences in circadian activity were investigated along with locomotion elicited by amphe...

    journal_title：Psychoneuroendocrinology

    pub_type： 杂志文章

    doi：10.1016/s0306-4530(00)00033-0

    authors： Bratt AM,Kelley SP,Knowles JP,Barrett J,Davis K,Davis M,Mittleman G

    更新日期：2001-02-01 00:00:00

  • Sex-specific effects of intranasal oxytocin on thermal pain perception: A randomised, double-blind, placebo-controlled cross-over study.

    abstract：:Chronic neck and shoulder pain (CNSP) is a common musculoskeletal disorder in adults, which is linked to hypersensitivity to noxious stimuli. The hormone oxytocin has been implicated as a potential therapeutic for the management of chronic pain disorders, and has been suggested to have sex-specific effects on the sali...

    journal_title：Psychoneuroendocrinology

    pub_type： 临床试验,杂志文章,随机对照试验

    doi：10.1016/j.psyneuen.2017.05.028

    authors： Tracy LM,Labuschagne I,Georgiou-Karistianis N,Gibson SJ,Giummarra MJ

    更新日期：2017-09-01 00:00:00

  • Grief, depressive symptoms, and inflammation in the spousally bereaved.

    abstract：:Grief is conceptualized by strong negative emotions, which include longing, sadness, and preoccupations with thoughts, recollections, and images of the spouse. In the initial months after the loss of a spouse, those who are widowed are at risk for cardiovascular problems and premature mortality. In the general populat...

    journal_title：Psychoneuroendocrinology

    pub_type： 杂志文章

    doi：10.1016/j.psyneuen.2018.10.006

    authors： Fagundes CP,Brown RL,Chen MA,Murdock KW,Saucedo L,LeRoy A,Wu EL,Garcini LM,Shahane AD,Baameur F,Heijnen C

    更新日期：2019-02-01 00:00:00

  • Prolactin response to low-dose haloperidol challenge in schizophrenic, non-schizophrenic psychotic, and control subjects.

    abstract：:Haloperidol was administered IV to 46 male psychotic inpatients and 28 male control subjects. A two-way analysis of covariance, with age as the covariate, revealed that DSM-III schizophrenics (n = 27) had a lower prolactin response to haloperidol than did the controls (n = 28). There were no significant differences be...

    journal_title：Psychoneuroendocrinology

    pub_type： 杂志文章

    doi：10.1016/0306-4530(90)90033-6

    authors： Copolov DL,Keks NA,Kulkarni J,Singh BS,McKenzie D,McGorry P,Hill C

    更新日期：1990-01-01 00:00:00

  • Kinetic modeling of hormone release: application to time-averaged met-enkephalin release.

    abstract：:The time course of hormone concentrations in response to a stimulus can be characterized with kinetic methods to express rates of hormone release and elimination, total amount of hormone release and expected best times for blood sampling. Routine application of kinetic methods should increase the sensitivity and appli...

    journal_title：Psychoneuroendocrinology

    pub_type： 杂志文章

    doi：10.1016/0306-4530(87)90066-7

    authors： Swartz CM,Quock RM

    更新日期：1987-01-01 00:00:00

  • Cortisol secretion in depressed, and at-risk adults.

    abstract：:Distinct patterns of cortisol secretion have been associated with depression in past research, but it remains unclear whether individuals at-risk for depression may also have similar patterns of cortisol secretion. This is the first study to date of both naturalistic diurnal cortisol secretion and cortisol reactivity ...

    journal_title：Psychoneuroendocrinology

    pub_type： 杂志文章

    doi：10.1016/j.psyneuen.2012.09.019

    authors： Dienes KA,Hazel NA,Hammen CL

    更新日期：2013-06-01 00:00:00

  • The relationship between the pineal gland and the pituitary--adrenal axis in health, endocrine and psychiatric conditions.

    abstract：:Evidence is reviewed in favour of a close relationship between the pineal hormone, melatonin and ACTH--cortisol in man. Subgroups of patients with Cushing's disease as well as with major depressive disorder have low levels of nocturnal serum melatonin. Depressed patients with an abnormal dexamethasone suppression test...

    journal_title：Psychoneuroendocrinology

    pub_type： 杂志文章,评审

    doi：10.1016/0306-4530(83)90042-2

    authors： Wetterberg L

    更新日期：1983-01-01 00:00:00

  • The serum glucose response to acute stress is sensitive to the intensity of the stressor and to habituation.

    abstract：:The reliability of serum glucose concentrations as an index of habituation to chronic stress was evaluated in adult male rats. The glucose response to immobilization was attenuated by six days of previous chronic exposure to the same stressor, the degree of reduction being related to the duration (15 min, 1 hr or 4 hr...

    journal_title：Psychoneuroendocrinology

    pub_type： 杂志文章

    doi：10.1016/0306-4530(90)90059-i

    authors： Armario A,Marti J,Gil M

    更新日期：1990-01-01 00:00:00

  • Sexual dysfunction and neuroendocrine correlates of posttraumatic stress disorder in combat veterans: Preliminary findings.

    abstract：:Sexual dysfunction is not a symptom of PTSD but is a common clinical complaint in trauma survivors with this disorder. In that there are biological parallels in the neuroendocrine processes underlying both PTSD and sexual behavior, we conducted an exploratory investigation of the relationship of PTSD and related neuro...

    journal_title：Psychoneuroendocrinology

    pub_type： 杂志文章

    doi：10.1016/j.psyneuen.2015.10.015

    authors： Lehrner A,Flory JD,Bierer LM,Makotkine I,Marmar CR,Yehuda R

    更新日期：2016-01-01 00:00:00

  • Stress-related peripheral neuroendocrine-immune interactions in women with ulcerative colitis.

    abstract：OBJECTIVES:The mechanisms underlying the interaction of psychological stress with the disease course in inflammatory bowel diseases remain unclear. We analyzed the neuroendocrine and cellular immune responses to public speaking stress, and the in vitro adrenergic and glucocorticoid modulation of cytokine production by ...

    journal_title：Psychoneuroendocrinology

    pub_type： 杂志文章

    doi：10.1016/j.psyneuen.2007.09.003

    authors： Langhorst J,Cobelens PM,Kavelaars A,Heijnen CJ,Benson S,Rifaie N,Dobos GJ,Schedlowski M,Elsenbruch S

    更新日期：2007-09-01 00:00:00

  • Assessing cortisol from hair samples in a large observational cohort: The Whitehall II study.

    abstract：:Hair cortisol concentrations (HCC) have been suggested to reflect long-term integrated cortisol levels, but most evidence of associations with co-variates is from small samples of healthy volunteers. The objective of this study was to describe the collection of hair samples in a large cohort study and report associati...

    journal_title：Psychoneuroendocrinology

    pub_type： 杂志文章

    doi：10.1016/j.psyneuen.2016.07.214

    authors： Abell JG,Stalder T,Ferrie JE,Shipley MJ,Kirschbaum C,Kivimäki M,Kumari M

    更新日期：2016-11-01 00:00:00

  • Swim stress differentially blocks CRF receptor mediated responses in dorsal raphe nucleus.

    abstract：:Modulation of the serotonergic (5-HT) neurotransmitter system arising from the dorsal raphe nucleus (DR) is thought to support the behavioral effects of swim stress, i.e., immobility. In vivo pharmacological and anatomical studies suggest that corticotropin-releasing factor (CRF) and γ-aminobutyric acid (GABA) synapti...

    journal_title：Psychoneuroendocrinology

    pub_type： 杂志文章

    doi：10.1016/j.psyneuen.2010.03.003

    authors： Lamy CM,Beck SG

    更新日期：2010-10-01 00:00:00

  • Psychoneuroendocrinology of anorexia nervosa.

    abstract：:It is suggested that the symptoms of anorexia nervosa are physiological responses to starvation. There is no evidence of a neural or non-neural dysfunction that predisposes women for anorexia nervosa and the endocrine and psychological consequences of starvation are reversed once patients have re-learnt how to eat and...

    journal_title：Psychoneuroendocrinology

    pub_type： 杂志文章,评审

    doi：10.1016/j.psyneuen.2006.09.006

    authors： Södersten P,Bergh C,Zandian M

    更新日期：2006-11-01 00:00:00

  • Serotonin 2C receptor antagonism ameliorates novelty-induced hypophagia in aged mice.

    abstract：:This study was conducted to clarify the role of serotonin (5-hydroxytryptamine, 5-HT) 2C receptor (5-HT2CR) signaling during novelty-induced hypophagia in aged mice. Male C57BL/6J mice [6-week-old (young) and 79-80-week-old (aged) mice] were exposed to a novel environment, and its effects on feeding behavior, stress h...

    journal_title：Psychoneuroendocrinology

    pub_type： 杂志文章

    doi：10.1016/j.psyneuen.2013.03.014

    authors： Nahata M,Muto S,Nakagawa K,Ohnishi S,Sadakane C,Saegusa Y,Iizuka S,Hattori T,Asaka M,Takeda H

    更新日期：2013-10-01 00:00:00

  • Sex steroids, sexual behavior, and selection attention for erotic stimuli in women using oral contraceptives.

    abstract：:The relationship between sex steroids and sexual behavior was examined in 19 oral contraceptive users. Retrospective assessment of sexual attitudes were obtained and women completed daily ratings of sexual behavior and well-being for 28 days. Plasma levels of free testosterone (T), estradiol, and progesterone were mea...

    journal_title：Psychoneuroendocrinology

    pub_type： 杂志文章

    doi：10.1016/0306-4530(93)90060-x

    authors： Alexander GM,Sherwin BB

    更新日期：1993-01-01 00:00:00

  • Androgenic influences on neural asymmetry: Handedness and language lateralization in individuals with congenital adrenal hyperplasia.

    abstract：:This study tested the hypothesis that prenatal androgen levels influence hand preferences and language lateralization, two manifestations of neural asymmetry. Participants were individuals with congenital adrenal hyperplasia (CAH, a genetic disorder that results in excess adrenal androgen production beginning prenatal...

    journal_title：Psychoneuroendocrinology

    pub_type： 临床试验,杂志文章

    doi：10.1016/S0306-4530(03)00145-8

    authors： Mathews GA,Fane BA,Pasterski VL,Conway GS,Brook C,Hines M

    更新日期：2004-07-01 00:00:00

  • Hair cortisol as a biomarker of stress and resilience in South African mixed ancestry females.

    abstract：BACKGROUND:Hair cortisol concentrations (HCC) are increasingly used as a biomarker of stress, however limited research exists regarding the relationship between HCC and protective factors, such as resilience. Additionally, studies measuring HCC need to account for possible confounders, and these factors have not been e...

    journal_title：Psychoneuroendocrinology

    pub_type： 杂志文章

    doi：10.1016/j.psyneuen.2019.104543

    authors： van den Heuvel LL,Acker D,du Plessis S,Stalder T,Suliman S,Thorne MY,Kirschbaum C,Seedat S

    更新日期：2020-03-01 00:00:00