The relationship between the pineal gland and the pituitary--adrenal axis in health, endocrine and psychiatric conditions.

abstract：:Grief is conceptualized by strong negative emotions, which include longing, sadness, and preoccupations with thoughts, recollections, and images of the spouse. In the initial months after the loss of a spouse, those who are widowed are at risk for cardiovascular problems and premature mortality. In the general populat...

journal_title：Psychoneuroendocrinology

authors： Fagundes CP,Brown RL,Chen MA,Murdock KW,Saucedo L,LeRoy A,Wu EL,Garcini LM,Shahane AD,Baameur F,Heijnen C

更新日期：2019-02-01 00:00:00

abstract：:Hypothalamo-pituitary functions were examined in thirteen children with behavioral disorders (six with hyperkinesia, four with autism, two with tic and one with schizophrenia) before and during treatment with pimozide, an antidopaminergic drug. The mean (+/- S.E.M.) basal serum PRL level (24.5 +/- 4.2 ng/ml) during pi...

journal_title：Psychoneuroendocrinology

authors： Suwa S,Naruse H,Ohura T,Tsuruhara T,Takesada M,Yamazaki K,Mikuni M

更新日期：1984-01-01 00:00:00

abstract：:Studies of the salivary cortisol awakening response (CAR) may be confounded by delays between waking in the morning and obtaining the 'waking' salivary sample. We used wrist actigraphy to provide objective information about waking time, and studied the influence of delays in taking the waking sample on the CAR. Eighty...

journal_title：Psychoneuroendocrinology

authors： Dockray S,Bhattacharyya MR,Molloy GJ,Steptoe A

更新日期：2008-01-01 00:00:00

abstract：:Chronic psychological stress appears to accelerate biological aging, and oxidative damage is an important potential mediator of this process. However, the mechanisms by which psychological stress promotes oxidative damage are poorly understood. This study investigates the theory that cortisol increases in response to ...

journal_title：Psychoneuroendocrinology

authors： Aschbacher K,O'Donovan A,Wolkowitz OM,Dhabhar FS,Su Y,Epel E

更新日期：2013-09-01 00:00:00

abstract：:The basal activity of the hypothalamic-pituitary-adrenal axis is highly dynamic and is characterized by both circadian and ultradian (pulsatile) patterns of hormone secretion. Pulsatility of glucocorticoids has been determined to be critical for optimal transcriptional, neuroendocrine, and behavioral responses. We use...

journal_title：Psychoneuroendocrinology

authors： Danan D,Matar MA,Kaplan Z,Zohar J,Cohen H

更新日期：2018-01-01 00:00:00

abstract：:Nocturnal penile tumescence (NPT) and erectile response to visual erotic stimuli (VES) were measured, by means of a Rigiscan device, in nine hypogonadal men, and repeated after 3 months of androgen replacement. The same assessments were carried out once in 12 eugonadal controls. The number of satisfactory NPT response...

journal_title：Psychoneuroendocrinology

authors： Carani C,Granata AR,Bancroft J,Marrama P

更新日期：1995-01-01 00:00:00

abstract：:The hypothalamo-pituitary-adrenal (HPA) axis is hyperactive in major depressive disorder (MDD), and baseline cortisol levels are usually elevated in MDD patients, with alterations of the circadian hormone secretion pattern. The dexamethasone (DEX) suppression test (DST) has been extensively applied to diagnose a dysre...

journal_title：Psychoneuroendocrinology

authors： Steimer T,Python A,Schulz PE,Aubry JM

更新日期：2007-06-01 00:00:00

abstract：:Neurobehavioral symptoms are frequently reported in patients with diabetes. Nevertheless, the characterization of the specific symptom dimensions that develop in diabetic patients with respect to disease phenotype and treatment status remains obscure. This study comparatively assessed fatigue symptoms and cognitive pe...

journal_title：Psychoneuroendocrinology

authors： Lasselin J,Layé S,Barreau JB,Rivet A,Dulucq MJ,Gin H,Capuron L

更新日期：2012-09-01 00:00:00

abstract：:A prenatal hypothyroid state is associated with behavioral abnormalities in adulthood. Wistar Kyoto (WKY) rats exhibit hypothyroidism and increased depressive and anxiety-like behaviors. Thus, the WKY could illuminate the mechanisms by which the reversal of developmental hypothyroidism in humans and animals results in...

journal_title：Psychoneuroendocrinology

authors： Shukla PK,Sittig LJ,Andrus BM,Schaffer DJ,Batra KK,Redei EE

更新日期：2010-07-01 00:00:00

abstract：:Arginine Vasopressin modulates complex social and sexual behavior by enhancing social recognition, pair bonding, and aggression in non-human mammals. The influence of Arginine Vasopressin in human social and sexual behavior is, however, yet to be fully understood. We evaluated whether Arginine Vasopressin nasal spray ...

journal_title：Psychoneuroendocrinology

authors： Guastella AJ,Kenyon AR,Unkelbach C,Alvares GA,Hickie IB

更新日期：2011-02-01 00:00:00

abstract：:Sustained abnormalities of glucocorticoid levels have been associated with neuropsychiatric illnesses such as major depression, posttraumatic stress disorder (PTSD), panic disorder, and obsessive compulsive disorder. The pathophysiological effects of glucocorticoids may depend not only on the amount of glucocorticoid ...

journal_title：Psychoneuroendocrinology

authors： Pekary AE,Sattin A,Blood J,Furst S

更新日期：2008-10-01 00:00:00

abstract：INTRODUCTION:Childhood sexual abuse (CSA) has been associated with dysregulation of the hypothalamic-pituitary-adrenal (HPA) axis in non-pregnant samples. However, it is not yet known whether CSA is associated with HPA dysregulation over pregnancy. In the present study we assessed whether maternal cortisol levels acros...

journal_title：Psychoneuroendocrinology

authors： Bublitz MH,Stroud LR

更新日期：2012-09-01 00:00:00

abstract：:In order to determine whether central serotonin (5-HT) activity is related to sensitivity of insulin receptors, 19 healthy volunteers with normal basal glycemia and HbAlc were studied. The relationship between prolactin response to D-fenfluramine (delta PRL) in a challenge test and metabolic clearance rates (MCR) of g...

journal_title：Psychoneuroendocrinology

authors： Horácek J,Kuzmiaková M,Höschl C,Andĕl M,Bahbonh R

更新日期：1999-11-01 00:00:00

abstract：:Menstrually related symptoms and disorders are multidimensional and affect diverse physiologic systems. Elucidation of the pathophysiologic mechanisms of these disorders should allow for a more precise diagnosis, and provide direction for targeted therapeutic interventions. Several biologic mechanisms that underlie me...

journal_title：Psychoneuroendocrinology

authors： Halbreich U

更新日期：2003-08-01 00:00:00

abstract：:The bed nucleus of the stria terminalis (BNST) plays a critical role in fear and anxiety. The BNST is important for contextual fear learning, but the mechanisms regulating this function remain unclear. One candidate mechanism is corticotropin-releasing-factor (CRF) acting at CRF type 1 receptors (CRFr1s). Yet, there h...

journal_title：Psychoneuroendocrinology

authors： Asok A,Schulkin J,Rosen JB

更新日期：2016-08-01 00:00:00

abstract：:There is now an expanding volume of evidence to support the view that commensal organisms within the gut play a role in early programming and later responsivity of the stress system. The gut is inhabited by 10¹³-10¹⁴ micro-organisms, which is ten times the number of cells in the human body and contains 150 times as ma...

journal_title：Psychoneuroendocrinology

authors： Dinan TG,Cryan JF

更新日期：2012-09-01 00:00:00

abstract：:The reliability of serum glucose concentrations as an index of habituation to chronic stress was evaluated in adult male rats. The glucose response to immobilization was attenuated by six days of previous chronic exposure to the same stressor, the degree of reduction being related to the duration (15 min, 1 hr or 4 hr...

journal_title：Psychoneuroendocrinology

authors： Armario A,Marti J,Gil M

更新日期：1990-01-01 00:00:00

abstract：:The association between SES and health is well established; however, only a handful of studies have investigated the relationship between SES and daily cortisol parameters. Further, within this small literature, virtually no studies have looked at psychological factors that might mitigate this relationship. In this st...

journal_title：Psychoneuroendocrinology

authors： Zilioli S,Imami L,Slatcher RB

更新日期：2015-10-01 00:00:00

abstract：:Recent breakthroughs in cannabinoid research, including the identification of two cannabinoid receptors (CB receptors) and a family of endogenous ligands, the anandamides, may shed new light on the sequelae of pre- and perinatal exposure to cannabinoid receptor ligands and enable the experimental manipulation of the e...

journal_title：Psychoneuroendocrinology

authors： Fride E,Mechoulam R

更新日期：1996-02-01 00:00:00

abstract：:This study tested the hypothesis that prenatal androgen levels influence hand preferences and language lateralization, two manifestations of neural asymmetry. Participants were individuals with congenital adrenal hyperplasia (CAH, a genetic disorder that results in excess adrenal androgen production beginning prenatal...

journal_title：Psychoneuroendocrinology

authors： Mathews GA,Fane BA,Pasterski VL,Conway GS,Brook C,Hines M

更新日期：2004-07-01 00:00:00

abstract：BACKGROUND:Dysregulation of the hypothalamic-pituitary-adrenal (HPA) axis is implicated in the pathophysiology of post-traumatic stress disorder (PTSD). However, there has been little study of HPA stress reactivity in association with PTSD symptoms (PTSS) in children; and there is limited research on PTSD in low and mi...

journal_title：Psychoneuroendocrinology

authors： Zimmerman A,Halligan S,Skeen S,Morgan B,Fraser A,Fearon P,Tomlinson M

更新日期：2020-11-01 00:00:00

abstract：BACKGROUND:Serotonin influences the development of the hypothalamic-pituitary-adrenal (HPA) system; therefore prenatal exposure to selective serotonin reuptake inhibitor antidepressants (SSRIs) may alter HPA axis development and function. To address this, prenatal exposure to SSRIs and maternal mood were examined in re...

journal_title：Psychoneuroendocrinology

authors： Pawluski JL,Brain UM,Underhill CM,Hammond GL,Oberlander TF

更新日期：2012-07-01 00:00:00

abstract：BACKGROUND:Studies in mammals indicate a role for sex hormones in the regulation of hypothalamic-pituitary-adrenal (HPA)-axis reactivity. However, in humans, experimental paradigms investigating long-term exposure to sex hormones are sparse, limiting the understanding of the influence of sex hormones on HPA-axis activi...

journal_title：Psychoneuroendocrinology

authors： Fuss J,Claro L,Ising M,Biedermann SV,Wiedemann K,Stalla GK,Briken P,Auer MK

更新日期：2019-06-01 00:00:00

abstract：:Burnout is presumed to be the result of chronic stress, and chronic stress is known to affect the HPA-axis. To date, studies on HPA-axis functioning in burnout have showed inconsistent results. In the present study, a large sample (n=74) of clinically diagnosed burnout individuals, mostly on sick-leave, were included ...

journal_title：Psychoneuroendocrinology

authors： Mommersteeg PM,Heijnen CJ,Verbraak MJ,van Doornen LJ

更新日期：2006-02-01 00:00:00

abstract：:Oxytocin has been shown to affect human social information processing including recognition memory for faces. Here we investigated the neural processes underlying the effect of oxytocin on memorizing own-race and other-race faces in men and women. In a placebo-controlled, double-blind, between-subject study, participa...

journal_title：Psychoneuroendocrinology

authors： Herzmann G,Bird CW,Freeman M,Curran T

更新日期：2013-10-01 00:00:00

abstract：BACKGROUND:Sex differences in levels of C-reactive protein (CRP) are well established in adulthood, but little is known about when and why they emerge. Here, we tested longitudinal models of CRP levels from ages 9 to 21, when marked physical and behavioral changes could contribute to growing sex disparities in CRP. ME...

journal_title：Psychoneuroendocrinology

authors： Shanahan L,Copeland WE,Worthman CM,Erkanli A,Angold A,Costello EJ

更新日期：2013-10-01 00:00:00

abstract：BACKGROUND:Recent data suggest that ghrelin is involved in the pathophysiology of alcohol use disorders, affecting alcohol self-administration and craving. Gastric ghrelin secretion is reduced by stomach distension. We now tested the hypothesis whether the clinically well-known effects of high-volume water intake on cr...

journal_title：Psychoneuroendocrinology

authors： Koopmann A,Lippmann K,Schuster R,Reinhard I,Bach P,Weil G,Rietschel M,Witt SH,Wiedemann K,Kiefer F

更新日期：2017-11-01 00:00:00

abstract：BACKGROUND:Subliminal intragastric fatty acid infusion attenuates subjective and brain responses to negative emotion induction. However, the underlying gut-brain signaling mechanisms remain unclear, and it is unknown whether such effect equally applies to positive emotion. OBJECTIVE:We aimed to investigate the interac...

journal_title：Psychoneuroendocrinology

authors： Zhao D,Boey L,Weltens N,Biesiekierski JR,Iven J,Depoortere I,Tack J,Van Oudenhove L

更新日期：2019-10-01 00:00:00

abstract：:Allergic rhinitis (AR) is the fifth most common chronic disease, and the association between allergic disorders and anxiety is well-documented. To investigate how anxiety and stressors modulate skin prick test (SPT) responses and associated inflammatory responses, 28 men and women with AR were selected by clinical his...

journal_title：Psychoneuroendocrinology

authors： Kiecolt-Glaser JK,Heffner KL,Glaser R,Malarkey WB,Porter K,Atkinson C,Laskowski B,Lemeshow S,Marshall GD

更新日期：2009-06-01 00:00:00

abstract：:Different doses dexamethasone (0.25, 0.5, and 1 mg) or cortisol (30, 60, and 120 mg) were administered PO at 2230h to 39 depressed patients and 20 healthy subjects on nonsuccessive days. The inhibiting capacity of the two steroids on hypothalamo-pituitary axis (HPA) function was evaluated by measuring the plasma level...

journal_title：Psychoneuroendocrinology

authors： Gispen-de Wied CC,D'Haenen H,Verhoeven WM,Wynne HJ,Westenberg HG,Thijssen JH,Van Ree JM

更新日期：1993-01-01 00:00:00