Abstract:
:Nocturnal penile tumescence (NPT) and erectile response to visual erotic stimuli (VES) were measured, by means of a Rigiscan device, in nine hypogonadal men, and repeated after 3 months of androgen replacement. The same assessments were carried out once in 12 eugonadal controls. The number of satisfactory NPT responses, in terms of both circumference increase and rigidity, were less in the hypogonadal men than the controls and were significantly increased by androgen replacement, confirming the results of earlier studies. In terms of circumference increase, erectile response to VES did not differ between the hypogonadal men and the controls, and did not increase with androgen replacement. In terms of rigidity, the erectile response to VES did not differ between hypogonadal men and controls. However, in terms of both duration and maximum level of rigidity, there was a significant increase following androgen replacement in the hypogonadal men. These new findings, in relation to rigidity, require a modification of the earlier formulation, which saw NPT as androgen dependent and erectile response to VES as androgen independent. NPT, and possibly spontaneous erections at other times, clearly involve an androgen sensitive system. Erectile response to VES predominantly involves an androgen independent system but may also be influenced by androgen sensitive mechanisms.
journal_name
Psychoneuroendocrinologyjournal_title
Psychoneuroendocrinologyauthors
Carani C,Granata AR,Bancroft J,Marrama Pdoi
10.1016/0306-4530(95)00017-8subject
Has Abstractpub_date
1995-01-01 00:00:00pages
743-53issue
7eissn
0306-4530issn
1873-3360pii
0306-4530(95)00017-8journal_volume
20pub_type
临床试验,杂志文章abstract:BACKGROUND:Neurosteroids have been proposed to play an important role in the interaction between alcohol and GABA(A) receptors and for the symptomatology of premenstrual dysphoric disorder (PMDD). The primary aim of this study was to investigate possible alcohol-induced changes in allopregnanolone serum concentrations ...
journal_title:Psychoneuroendocrinology
pub_type: 临床试验,杂志文章,随机对照试验
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更新日期:2005-10-01 00:00:00
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pub_type: 临床试验,杂志文章
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journal_title:Psychoneuroendocrinology
pub_type: 杂志文章
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更新日期:2016-04-01 00:00:00
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journal_title:Psychoneuroendocrinology
pub_type: 临床试验,杂志文章
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pub_type: 杂志文章,随机对照试验
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更新日期:2012-07-01 00:00:00
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journal_title:Psychoneuroendocrinology
pub_type: 杂志文章
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更新日期:2012-01-01 00:00:00
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journal_title:Psychoneuroendocrinology
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更新日期:1990-01-01 00:00:00
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更新日期:1982-01-01 00:00:00
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journal_title:Psychoneuroendocrinology
pub_type: 杂志文章
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更新日期:1997-05-01 00:00:00
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pub_type: 杂志文章
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更新日期:2013-12-01 00:00:00
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journal_title:Psychoneuroendocrinology
pub_type: 杂志文章,随机对照试验
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更新日期:2016-12-01 00:00:00
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更新日期:1998-07-01 00:00:00
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pub_type: 临床试验,杂志文章
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更新日期:1995-01-01 00:00:00
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更新日期:2011-05-01 00:00:00
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更新日期:2014-10-01 00:00:00
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更新日期:2021-01-20 00:00:00
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pub_type: 杂志文章,评审
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更新日期:2014-04-01 00:00:00
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pub_type: 杂志文章,评审
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更新日期:2019-09-01 00:00:00
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