Toll-like receptors: new therapeutic targets for the treatment of atherosclerosis, acute coronary syndromes, and myocardial failure.

abstract：:Differences in the overall mortality for acute infarction in women vs men have been appreciated for some time. Some of these differences are based on the age at the time of presentation of women compared with men. Excess mortality in women is most clear at the younger end of the age spectrum. More careful examination ...

journal_title：Cardiology in review

authors： Feldman T,Silver R

更新日期：2000-07-01 00:00:00

abstract：:Intensive glycemic control significantly increases the risk of hypoglycemia in patients with diabetes mellitus. Recent data have shown that hypoglycemia may also be a marker of cardiovascular disease in these patients. We performed a systemic review and a meta-analysis to evaluate the relationship between severe hypog...

journal_title：Cardiology in review

authors： Malik AH,Yandrapalli S,Aronow WS,Jain D,Frishman WH,Panza JA,Cooper HA

更新日期：2020-09-01 00:00:00

abstract：:Primary pulmonary hypertension and cor pulmonale represent forms of precapillary pulmonary hypertension due to intrinsic lung disease. In the case of primary pulmonary hypertension, this is due to disease of the pulmonary vasculature while cor pulmonale is related to diseases of the pulmonary vasculature, airways, or ...

journal_title：Cardiology in review

authors： Lehrman S,Romano P,Frishman W,Rashid A,Dobkin J,Reichel J

更新日期：2002-09-01 00:00:00

abstract：:Myocarditis represents a heterogeneous final common pathway for myocardial inflammation of diverse etiologies and accounts for up to one-third of cases of dilated cardiomyopathy. The pathophysiology of viral myocarditis can be disaggregated into the effects of direct viral mediated injury, triggered acute and chronic ...

journal_title：Cardiology in review

authors： Ellis CR,Di Salvo T

更新日期：2007-07-01 00:00:00

abstract：:Despite recent advances in the management of chronic heart failure (CHF), the prognosis of many of these patients remains dire. The need for an accurate prognosis in these patients has led to the identification of several indicators purported to represent the impact of the disease. Such indicators often are obtained a...

journal_title：Cardiology in review

authors： Jorge Alves A,Ribeiro F,Sagiv M,Eynon N,Yamin C,Sagiv M,Oliveira J

更新日期：2010-07-01 00:00:00

abstract：:Mechanical valve thrombosis is a life-threatening event. Pregnancy is associated with a hypercoagulable state that further emphasizes the importance of adequate anticoagulation. This is associated with a therapeutic dilemma. Continued anticoagulation with warfarin throughout the first trimester can result in fetopathi...

journal_title：Cardiology in review

authors： Behrendt P,Schwartzkopff B,Perings S,Gerhardt A,Zotz RB,Strauer BE

更新日期：2002-11-01 00:00:00

abstract：:Cholesterol metabolism and transport has been a major focus in cardiovascular disease risk modification over the past several decades. Hydroxymethylglutaryl-CoA reductase inhibitors (statins) have been the most commonly used agents, with the greatest benefit in reducing both the primary and secondary risks of cardiova...

journal_title：Cardiology in review

authors： Grabie M,Tai CH,Frishman WH

更新日期：2019-09-01 00:00:00

abstract：:Short QT syndrome is a rare inherited autosomal dominant cardiac channelopathy associated with malignant ventricular and atrial arrhythmias. A shortened corrected QT interval is a marker for risk of malignant arrhythmias, which are secondary to increased transmural dispersion of repolarization. The underlying gain of ...

journal_title：Cardiology in review

authors： Khera S,Jacobson JT

更新日期：2016-07-01 00:00:00

abstract：:Interleukin 1β (IL-1β) is a proinflammatory cytokine that has been implicated in a number of rheumatologic and inflammatory conditions. The production and secretion of IL-1β from inflammatory cells is a tightly regulated process that has been extensively described and studied. In recent years, IL-1β has been associate...

journal_title：Cardiology in review

authors： McCarty S,Frishman W

更新日期：2014-07-01 00:00:00

abstract：:Chagas disease, caused by the parasite Trypanosoma cruzi, is an important cause of cardiac disease in endemic areas of Latin America. It is now being diagnosed in nonendemic areas because of immigration. Typical cardiac manifestations of Chagas disease include dilated cardiomyopathy, congestive heart failure, arrhythm...

journal_title：Cardiology in review

authors： Machado FS,Jelicks LA,Kirchhoff LV,Shirani J,Nagajyothi F,Mukherjee S,Nelson R,Coyle CM,Spray DC,de Carvalho AC,Guan F,Prado CM,Lisanti MP,Weiss LM,Montgomery SP,Tanowitz HB

更新日期：2012-03-01 00:00:00

abstract：:There is a sexual dimorphism in blood pressure: men tend to have higher blood pressures than women with functional ovaries, whereas ovariectomy or menopause tends to abolish the sexual dimorphism and cause women to develop a "male" pattern of blood pressure. Synthetic estrogens and progestins, found in oral contracept...

journal_title：Cardiology in review

authors： Calhoun DA,Oparil S

更新日期：1998-11-01 00:00:00

abstract：:The human intestine contains the largest and most diverse ecosystem of microbes. The main function of the intestinal bacterial flora is to limit the growth of potentially pathogenic microorganisms. However, the intestinal microbiota is increasingly emerging as a risk factor for the development of cardiovascular diseas...

journal_title：Cardiology in review

authors： Anselmi G,Gagliardi L,Egidi G,Leone S,Gasbarrini A,Miggiano GAD,Galiuto L

更新日期：2020-06-18 00:00:00

abstract：:Valvular endocarditis after percutaneous coronary intervention is unusual. We report a new case of mitral valve endocarditis after stent implantation to a saphenous vein graft. ...

journal_title：Cardiology in review

authors： Palmer ND,Ramsdale DR

更新日期：2005-05-01 00:00:00

abstract：:Endothelin is a potent vasoconstrictor substance that also can exert proliferative, inflammatory, and fibrotic changes in blood vessels and other organs. It acts on tissues in a paracrine and autocrine fashion, with local production and regulation occurring in both endothelial and nonendothelial cells. Endothelin stim...

journal_title：Cardiology in review

authors： Prasad VS,Palaniswamy C,Frishman WH

更新日期：2009-07-01 00:00:00

abstract：:Stress radionuclide myocardial perfusion imaging is a commonly used modality to evaluate patients with known or suspected coronary artery disease. The dual isotope rest thallium-201/stress technetium-99m sestamibi gated single-photon emission computed tomography protocol has gained increasing popularity for these appl...

journal_title：Cardiology in review

authors： Hachamovitch R

更新日期：1999-03-01 00:00:00

abstract：:Loop diuretics are central to the management of fluid overload in acute decompensated heart failure. However, a variance in the response to loop diuretics can alter a patient's clinical course and has an adverse effect on clinical outcomes. Thus, a diminished response to loop diuretics is an important clinical issue. ...

journal_title：Cardiology in review

authors： Bowman BN,Nawarskas JJ,Anderson JR

更新日期：2016-09-01 00:00:00

abstract：:Pulmonary arterial hypertension (PAH) is a progressive disorder with a poor prognosis. It is characterized by sustained elevation of pulmonary artery pressure (PAP) and pulmonary vascular resistance (PVR). It is defined hemodynamically by a mean PAP over 25 mm Hg, a pulmonary arterial wedge pressure of 15 mm Hg or les...

journal_title：Cardiology in review

authors： De Marco T

更新日期：2006-11-01 00:00:00

abstract：:We report a case of spontaneous coronary artery rupture associated with amphetamine abuse in a 31-year-old woman. The patient presented to the emergency department with sudden onset of central chest pain and a normal electrocardiogram. Cardiac enzymes were consistent with acute myocardial infarction. Drug screening wa...

journal_title：Cardiology in review

authors： Brennan K,Shurmur S,Elhendy A

更新日期：2004-09-01 00:00:00

abstract：:A decision-tree analysis was used to estimate the average cost per patient using the direct thrombin inhibitor argatroban for early treatment (<48 hours after thrombocytopenia onset) compared with delayed treatment (> or =48 hours after thrombocytopenia onset) of immune-mediated heparin-induced thrombocytopenia (HIT) ...

journal_title：Cardiology in review

authors： Arnold RJ,Kim R,Tang B

更新日期：2006-01-01 00:00:00

abstract：:Recent articles have inquired about the quality of care for women presenting with cardiovascular disease. The Cooperative Cardiovascular Project and the National Heart Failure Project, 2 Medicare databases, provide national data to address concerns that women receive poorer quality care than men. In these databases, s...

journal_title：Cardiology in review

authors： Gold LD,Krumholz HM

更新日期：2006-07-01 00:00:00

abstract：:Cardiovascular disease is the leading cause of morbidity and mortality among women in industrialized nations. Optimizing cardiovascular risk reduction is therefore of paramount importance, particularly among postmenopausal women, in whom the incidence of cardiovascular disease is highest. Accumulated data from a serie...

journal_title：Cardiology in review

authors： Mostaghel E,Waters D

更新日期：2003-01-01 00:00:00

abstract：:Sudden death (SD) is the most dramatic event in hypertrophic cardiomyopathy (HCM), often representing the first clinical manifestation of the disease, and the first concern of the clinicians who take care of such patients. HCM is now recognized as the primary cause of SD in young persons (<35 years of age), including ...

journal_title：Cardiology in review

authors： Efthimiadis GK,Zegkos T,Meditskou S,Hadjimiltiades S

更新日期：2014-09-01 00:00:00

abstract：:Cardiac resynchronization therapy (CRT) has become a mainstay therapy to improve clinical outcomes of patients with left ventricular systolic dysfunction and a wide QRS complex, in addition to guideline-directed medical therapy. As clinical experience with CRT continues to expand, the device and lead design, along wit...

journal_title：Cardiology in review

authors： Ng CY,Heist EK

更新日期：2017-01-01 00:00:00

abstract：:Cardiac rupture after a myocardial infarction is an uncommon event with devastating consequences. Although the clinical features of rupture have been described, the genetic and molecular influences on this outcome in patients are less certain. In mice, at least 17 genetic models have been developed that enhance or sup...

journal_title：Cardiology in review

authors： Sane DC,Mozingo WS,Becker RC

更新日期：2009-11-01 00:00:00

abstract：:This literature review examines the association of social and psychologic characteristics among women with a) the risk of developing coronary heart disease and b) prognosis and recovery after disease has become manifest. Studies of psychosocial risk factors are often conflicting. These divergent findings can result fr...

journal_title：Cardiology in review

authors： Eaker ED

更新日期：1998-05-01 00:00:00

abstract：:It has been shown in rodents and newborn babies that brown adipose tissue (BAT) plays an important role in the generation of heat for maintenance of core body temperature. BAT is responsible for the process of adaptive thermogenesis, which involves heat generation in response to a drop in the environment's temperature...

journal_title：Cardiology in review

authors： Mund RA,Frishman WH

更新日期：2013-11-01 00:00:00

abstract：:About 50 years ago, Norman Jefferis Holter invented a device that opened the possibility of recording heart activity over long periods of time. This invention, together with the rapid developments in electronics, has enabled a revolutionary change in the diagnosis and management of cardiac diseases. Ambulatory cardiac...

journal_title：Cardiology in review

authors： Romero I

更新日期：2013-09-01 00:00:00

abstract：:The obesity epidemic has reached unprecedented proportions in Western society. Evidence continues to accumulate that obesity is associated with significant morbidity and mortality and in particular that it is an independent risk factor for cardiovascular disease (CVD). The association of obesity with CVD and its risk ...

journal_title：Cardiology in review

authors： Melanson KJ,McInnis KJ,Rippe JM,Blackburn G,Wilson PF

更新日期：2001-07-01 00:00:00

abstract：:Reverse redistribution is a well-known pattern found when performing thallium myocardial scintigraphy, and it has been implicated as an indicator of myocardial ischemia. Much more rarely, when using technetium compounds, which do not redistribute, a similar pattern is noted after the second injection of the radiotrace...

journal_title：Cardiology in review

authors： Antonopoulos A,Galanopoulou K,Katsafados I,Siantos E

更新日期：2004-05-01 00:00:00

abstract：:The field of durable left ventricular assist devices has advanced dramatically since its introduction into the clinical realm. From the first-generation pulsatile HeartMate XVE device to the second-generation continuous axial flow HeartMate-2 to the current third-generation centrifugal flow devices, the left ventricul...

journal_title：Cardiology in review

authors： Levine A,Gass A

更新日期：2019-11-01 00:00:00