Abstract：
:We investigated the frequency and the clinical relevance of hepatitis B virus (HBV) pre-S mutations in Qidong, China. The results showed HBV pre-S mutants were detected in 48.4% (47/97) of patients with HBV infection. Both pre-S deletion and pre-S2 start codon mutations were more frequently found in HCC than in CH patients (51.1% vs. 18.0%, P < 0.01 and 21.2% vs. 8.0%, P = 0.06). In most cases, pre-S mutants coexisted with the wild-type HBV strain. Longitudinal observation clearly revealed that in four of five cases, HBV deletion mutants emerged during the course of HBV infection and eventually became the predominant or exclusive viral population at the stage of HCC. Thus, it was concluded that HBV pre-S mutations were highly prevalent and closely related to HCC in Qidong. Our results also provided direct evidence that pre-S deletion mutants were not acquired from the beginning of infection but arose de novo during the progression of liver disease.
journal_name
Arch Viroljournal_title
Archives of virologyauthors
Cao Z,Bai X,Guo X,Jin Y,Qian G,Tu Hdoi
10.1007/s00705-008-0176-9subject
Has Abstractpub_date
2008-01-01 00:00:00pages
1807-12issue
10eissn
0304-8608issn
1432-8798journal_volume
153pub_type
杂志文章abstract：:Retrovirus infectivity is the result of a cooperative interaction of three structural genes, gag, pol, and env. Since the L-cell endogenous retrovirus (LCV) lacks the env gene translation product, our aim was to study the biological and molecular basis of its non-infectiousness. Fusion experiments between LCV and homo...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/BF01315566
更新日期：1988-01-01 00:00:00
abstract：:A xenotropic Moloney murine leukemia virus-derived recombinant retrovirus (MMuLVSVnlslacZ) has been utilized to study the mechanism of virus entry into endothelial and epithelial porcine cells. In the genome of this recombinant retrovirus, the nlslacZ reporter gene is under the transcriptional control of both LTR and ...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/BF01314625
更新日期：1992-01-01 00:00:00
abstract：:The gene coding for the nucleocapsid protein NP of the influenza A virus recombinant strain 413 1,1 was characterized biochemically by molecular hybridization and fingerprint analysis. The data presented suggest that this NP gene has evolved by intracistronic recombination between NP genes of virus N and the fowl plag...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/BF01322701
更新日期：1980-01-01 00:00:00
abstract：:Mycobacteriophage archival stocks have been kept for ca. 20-50 years in Japan. In this study, we attempted to recover mycobacteriophages from 50 archival stocks and briefly analyzed the recovered phages. The phages were recovered from 72.2% (13/18) of the lyophilized stocks that had been stored for 47-56 years. Moreov...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s00705-018-3788-8
更新日期：2018-07-01 00:00:00
abstract：:Amino acids Lys34, His36, and Phe37 were substituted by PCR-mediated, site-directed mutagenesis for three Trp's in the AcNPV polyhedrin sequence. Phase contrast microscopy revealed refringent, amorphous polyhedra in the nuclei of infected cells. Electron microscopy confirmed a great variation in form and size of the m...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s007050050675
更新日期：2000-01-01 00:00:00
abstract：:Genetic analysis of the complete haemagglutinin (HA) gene of fourteen Nigerian avian influenza isolates showed multiple basic amino acids at the cleavage site (321PQRERRRK del R*GLF333), characteristic of highly pathogenic avian influenza (HPAI). Substitution of Gln to Lys at position 322 (H5-specific numbering) was i...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s00705-016-3149-4
更新日期：2017-03-01 00:00:00
abstract：:Bovine herpesvirus types 1 (BoHV-1) and 5 (BoHV-5) are two closely related alphaherpesviruses. BoHV-1 causes several syndromes in cattle, including respiratory disease and sporadic cases of encephalitis, whereas BoHV-5 is responsible for meningoencephalitis in calves. Although both viruses are neurotropic, they differ...
journal_title：Archives of virology
pub_type： 杂志文章,评审
doi：10.1007/s00705-019-04494-5
更新日期：2020-02-01 00:00:00
abstract：:Chrysanthemums worldwide suffer from a high incidence of infection with chrysanthemum virus B (CVB), a member of the genus Carlavirus, family Betaflexiviridae. Three major lineages or strains of this virus have been found in India, but none have been characterized beyond the genetic variation they display in their coa...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s00705-011-1190-x
更新日期：2012-03-01 00:00:00
abstract：:We previously isolated the monopartite begomovirus tomato leaf curl Java virus (ToLCJAV) and satellite DNAbeta02 from the same naturally infected tomato source in Indonesia. ToLCJAV induced mild leaf curl symptoms in Nicotiana benthamiana plants; DNAbeta02 encoded the betaC1 gene and produced severe leaf curl symptoms...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s00705-007-0957-6
更新日期：2007-01-01 00:00:00
abstract：:At necropsy, several dogs which died showing symptoms of hemorrhagic diarrhea, had significant lesions of the mucosa that were found especially in the duodenum and upper part of the small bowel. Study of ultrathin sections from the diseased mucosa revealed particles resembling parvoviruses in altered nuclei of cells o...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/BF01320586
更新日期：1979-01-01 00:00:00
abstract：:In this study, we describe a novel mycovirus isolated from Trichoderma asperellum, which was designated Trichoderma asperellum dsRNA Virus 1 (TaRV1). The sequence analysis revealed that TaRV1 has two discontinuous open reading frames (ORF), ORF1 and ORF2. A hypothetical protein and an RNA-dependent RNA polymerase are ...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s00705-018-3988-2
更新日期：2018-12-01 00:00:00
abstract：:A large sheep flock screened over a two-year period showed active spreading of Schmallenberg virus (SBV) during the summers of 2011 and 2012. Transplacental infections were observed during the two associated lambing periods (the winters of 2012 and 2013). Analysis of small (S) segment sequences of 38 SBV-positive samp...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s00705-016-2787-x
更新日期：2016-05-01 00:00:00
abstract：:Parechoviruses (PeVs) are highly prevalent viruses worldwide. Over the last decades, several studies have been published on PeV epidemiology in Europe, Asia and North America, while information on other continents is lacking. The aim of this study was to describe PeV circulation in a cohort of children in Malawi, Afri...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s00705-018-04131-7
更新日期：2019-03-01 00:00:00
abstract：:It is shown that reovirus capsid inner layer consists of 132 capsomeres with a skewed icosahedral pattern of T = 13 (left). 780 structural units composing capsomeres are integrated into trimers. The boundary between capsomeres runs between the structural units forming trimers. ...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/BF01313903
更新日期：1987-01-01 00:00:00
abstract：:Peritoneal exudate cells (PEC) of DBA/2 mice, after 7 days of in vitro preculture and consisting of virtually 100 per cent macrophages, were able to support the replication of Herpes Simplex Virus type 1 strain WAL (HSV). Using a standard medium based on Dulbecco's Modified Eagle Medium (D-MEM), no virus replication w...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/BF01309370
更新日期：1984-01-01 00:00:00
abstract：:The IL28B gene is associated with spontaneous or treatment-induced HCV viral clearance. However, the mechanism by which the IL28B single nucleotide polymorphism (SNP) affects the extra-hepatic HCV immune responses and its relationship to HCV pathogenesis have not been thoroughly investigated. To examine the mechanism ...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s00705-016-3015-4
更新日期：2016-11-01 00:00:00
abstract：:Thirty-seven clinical isolates of coxsackievirus (CV) serotypes B-1, B-3, B-4, and B-5 were inoculated into male SJL mice. Twelve strains resulted in minor abnormalities of glucose metabolism in one or more of six infected mice (Tables 1 and 2). Sequential infection of male SJL mice with CVB-3, CVB-4, and CVB-5 result...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/BF01309826
更新日期：1985-01-01 00:00:00
abstract：:Utilizing co-transfection of DNA from glycoprotein gB- strain of HSV1 and cloned fragments of several simian alpha-herpesviruses containing the UL26, UL27 (gB glycoprotein), and UL28 gene homologs, replication-competent recombinant viruses were produced. Genetic analysis of one HSV1/SA8 recombinant (HSV1/SgB) demonstr...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s007050050114
更新日期：1997-01-01 00:00:00
abstract：:Pigeon circovirus (PiCV) is taxonomically classified as a member of the Circovirus genus, family Circoviridae. The virus contains a single stranded DNA genome of approximately 2 kb, with minor length variations among different isolates. The occurrence of PiCV infections in pigeons (Columba livia) has been documented w...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s00705-018-3990-8
更新日期：2018-11-01 00:00:00
abstract：:Begomovirus infection is becoming a threat in fresh-market tomato in Argentina, where mixed infections with begomoviruses are common. The complete sequence of a begomovirus isolate infecting tomato sampled in Salta was molecularly characterized. Phylogenetic analysis showed that this virus isolate is closely related t...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s00705-012-1355-2
更新日期：2012-10-01 00:00:00
abstract：:Previously, we identified serological immunodeterminants of African swine fever virus (ASFV), including pK205R and pB602L, without homologues in the database. pK205R is expressed as a 33-kD protein from 4 h post-infection onward, initially diffusely distributed throughout cells, and subsequently in viral factories. pK...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s00705-008-0246-z
更新日期：2008-01-01 00:00:00
abstract：:Unfortunately, the original article was published with incorrect accession number and the correct version is updated here. ...
journal_title：Archives of virology
pub_type： 杂志文章,已发布勘误
doi：10.1007/s00705-019-04326-6
更新日期：2019-09-01 00:00:00
abstract：:Six isolates of Suid herpesvirus 1 (SHV-1) collected from clinical outbreaks of Aujeszky's disease (AD) in Jutland in January-February, 1985, were compared by restriction fragment pattern (RFP) analyses with older SHV-1 isolates from Jutland as well as with SHV-1 isolates from different parts of West Germany and Irela...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/BF01310912
更新日期：1988-01-01 00:00:00
abstract：:Five avian paramyxoviruses of serotype 8 (APMV-8) were isolated during a study monitoring wild birds in Kazakhstan in 2013 and each was further characterized. The viruses were isolated from three White-fronted geese (Anser albifrons), one Whooper swan (Cygnus cygnus), and one Little stint (Calidris minuta). Before our...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s00705-017-3593-9
更新日期：2018-02-01 00:00:00
abstract：:In order to prepare H5N1 influenza virus vaccine, the hemagglutinins (HAs) of 14 H5 virus isolates from water birds in Asia were antigenically and genetically analyzed. Phylogenetic analysis of the H5 HA genes revealed that 13 isolates belong to Eurasian and the other one to North American lineages. Each of the deduce...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s00705-008-0226-3
更新日期：2008-01-01 00:00:00
abstract：:We determined the complete nucleotide sequence of EDRD-1, a Japanese strain of the North American type-Porcine reproductive and respiratory syndrome virus (PRRSV), and identified a novel 117-base deletion and 108-base insertion previously reported in the nsp2 gene of the SP strain, which contains the largest genome am...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s00705-008-0098-6
更新日期：2008-01-01 00:00:00
abstract：:Codiaeum variegatum (common name, garden croton) is an ornamental plant grown for its bright yellow variegated leaf morphology. Two C. variegatum plants with upward leaf curling and vein swelling symptoms were collected in Faisalabad, Pakistan. Sequencing of clones obtained by PCR amplification with specific primers s...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s00705-020-04633-3
更新日期：2020-08-01 00:00:00
abstract：:Since late 2018, foot-and-mouth disease (FMD) has reemerged and rapidly swept through pig farms in North and Central Vietnam, despite widespread use of commercial FMD vaccines. To investigate the FMD virus (FMDV) strains responsible for the current epidemics, 40 FMDV samples were collected from 17 provinces during Nov...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s00705-020-04763-8
更新日期：2020-11-01 00:00:00
abstract：:The sequence variability of Barley yellow dwarf virus-PAV (PAV) and Barley yellow dwarf virus-MAV (MAV) was studied by comparing 502 nucleotides from the coat protein-encoding region of six isolates from Latvia and four from Sweden. The diversity within MAV was low (>97% sequence identity), also when compared to isola...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s00705-003-0242-2
更新日期：2004-04-01 00:00:00
abstract：:A nucleotide fragment encoding amino acids 29 to 94 in the E-protein of 28 dengue-2 isolates of diverse geographic and host origins was examined by direct sequencing of a polymerase chain reaction (PCR)-amplified product, and compared to six previously published sequences. Nucleotide divergence ranged from 0 to 19.8% ...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/BF01316895
更新日期：1993-01-01 00:00:00
