Abstract：
AIMS:To assess to which extent lowering the level of HbA1c influences the 10-year risk of coronary heart disease (CHD) and all-cause mortality in patients with type 2 diabetes mellitus. METHODS:A literature search in Pubmed and Embase was performed, and the absolute risks in the results of the relevant and valid studies compared. RESULTS:Each study shows that with a decreasing percentage of HbA1c, both the risk of developing CHD and the risk of mortality decrease. CONCLUSIONS:Lowering HbA1c in type 2 diabetics decreases the absolute risk of developing CHD by 5-17%, as well as decreasing all-cause mortality by 6-15%.
journal_name
Prim Care Diabetesjournal_title
Primary care diabetesauthors
ten Brinke R,Dekker N,de Groot M,Ikkersheim Ddoi
10.1016/j.pcd.2007.12.004subject
Has Abstractpub_date
2008-02-01 00:00:00pages
45-9issue
1eissn
1751-9918issn
1878-0210pii
S1751-9918(07)00184-2journal_volume
2pub_type
杂志文章,评审abstract：AIMS:To investigate whether long-term mortality or clinical outcomes differed between patients diagnosed with type 2 diabetes mellitus and presenting with HbA1c within or above normal range at time of diagnosis. METHODS:Data were from a population-based sample of 1136 individuals with newly diagnosed type 2 diabetes m...
journal_title：Primary care diabetes
pub_type： 杂志文章
doi：10.1016/j.pcd.2012.09.001
更新日期：2013-04-01 00:00:00
abstract：:Many patients with type 2 diabetes continue to have poor glycaemic control and would benefit from insulin therapy. However, resistance to the introduction of insulin therapy can be high on both the part of the healthcare provider and the patient. A number of new, long-acting basal insulins are in development that prov...
journal_title：Primary care diabetes
pub_type： 杂志文章,评审
doi：10.1016/j.pcd.2013.09.003
更新日期：2014-07-01 00:00:00
abstract：AIMS:To investigate whether metabolic syndrome (MetS) is associated with erectile dysfunction (ED) among apparently healthy men when depressive symptoms and serum testosterone levels are taken into account. METHODS:A study population of 549 men at risk for cardiovascular disease or type 2 diabetes was drawn from the p...
journal_title：Primary care diabetes
pub_type： 杂志文章
doi：10.1016/j.pcd.2019.12.008
更新日期：2020-10-01 00:00:00
abstract：AIMS:To assess perceptions surrounding diabetes self-management (DSM) behaviors in Arab American patients with diabetes. METHODS:A 39-item survey was constructed from focus group discussions designed to better understand the impact of Arab American culture on DSM behaviors. The survey assessed perceptions about diet, ...
journal_title：Primary care diabetes
pub_type： 杂志文章
doi：10.1016/j.pcd.2019.09.002
更新日期：2020-06-01 00:00:00
abstract：AIMS:To analyze the use of pain medication among community-dwelling people aged 65 years or older with and without type 2 diabetes in primary care. METHODS:A total of 187 patients with and 176 patients without diabetes were randomly selected from a primary care sample of 389 patients with diabetes and 604 age- and gen...
journal_title：Primary care diabetes
pub_type： 杂志文章
doi：10.1016/j.pcd.2020.05.016
更新日期：2020-12-01 00:00:00
abstract：AIM:To compare the prevalence of psychological distress and mental disorders between diabetes and non-diabetes sufferers and to identify associated factors. METHODS:Case-control study based on data from the 2006 to 2007 Spanish National Health Survey. We identified 2193 type 2 diabetic adults. Non-diabetic controls we...
journal_title：Primary care diabetes
pub_type： 杂志文章
doi：10.1016/j.pcd.2011.10.002
更新日期：2012-07-01 00:00:00
abstract：:Seasonal variations in fasting glucose and HbA1c levels in 638 diabetic patients (attending a primary care diabetic clinic during 2003-2007) were examined and found to be significantly higher in colder than in warmer months. Moreover, there were apparent peaks in fasting glucose levels after Christmas and Easter month...
journal_title：Primary care diabetes
pub_type： 杂志文章
doi：10.1016/j.pcd.2009.05.004
更新日期：2009-05-01 00:00:00
abstract：AIMS:We investigated to clarify factors associated with the efficacy of sitagliptin, a dipeptidyl peptidase (DPP)-IV inhibitor, for glycemic control including the confounding effect of concomitant drugs in patients with type 2 diabetes. METHODS:We included type 2 diabetes patients with HbA1c levels of ≥7% who were not...
journal_title：Primary care diabetes
pub_type： 杂志文章,多中心研究
doi：10.1016/j.pcd.2014.01.008
更新日期：2014-10-01 00:00:00
abstract：AIMS:To assess the diagnostic accuracy of the Finnish Diabetes Risk Score (FINDRISC) for undiagnosed T2DM and to compare its performance with the Latin-American FINDRISC (LA-FINDRISC) and the Peruvian Risk Score. MATERIALS AND METHODS:A population-based study was conducted. T2DM and undiagnosed T2DM were defined using...
journal_title：Primary care diabetes
pub_type： 杂志文章
doi：10.1016/j.pcd.2018.07.015
更新日期：2018-12-01 00:00:00
abstract：BACKGROUND:Data relating to the association between neck circumference (NC) and metabolic syndrome (MetS) in Southeast Asian population are scarce. AIMS:We aimed to investigate association between NC and MetS in Thai adults, and to determine gender-specific NC cutoff values for predicting MetS. METHODS:This cross-sec...
journal_title：Primary care diabetes
pub_type： 杂志文章
doi：10.1016/j.pcd.2019.08.007
更新日期：2020-06-01 00:00:00
abstract：:Our study demonstrates that Ipswich Touch Test is reliable and comparable to established standardized tests that identify the risk of foot ulceration among Saudi patients with diabetes mellitus. The simplicity of the test will assist in overcoming the barriers to screen for and detect the risk of foot ulceration. ...
journal_title：Primary care diabetes
pub_type： 杂志文章
doi：10.1016/j.pcd.2014.10.007
更新日期：2015-08-01 00:00:00
abstract：OBJECTIVE:The aim of this research study was to ascertain the awareness of Maltese family doctors to the prevalence and significance of impaired glucose regulation and early diagnosis of type 2 diabetes and whether practices were influenced by employment status, post-graduate training in diabetes or years since graduat...
journal_title：Primary care diabetes
pub_type： 杂志文章
doi：10.1016/j.pcd.2013.12.003
更新日期：2014-10-01 00:00:00
abstract：BACKGROUND:The incidence of type 2 diabetes (T2DM) is increasing. Having a pregnancy complicated by gestational diabetes mellitus (GDM) is a potent risk factor for the later development of T2DM. AIMS:To explore the characteristics of women diagnosed with GDM in a single centre and their follow up for progression to T2...
journal_title：Primary care diabetes
pub_type： 杂志文章
doi：10.1016/j.pcd.2020.05.010
更新日期：2020-12-01 00:00:00
abstract：AIMS:To determine the status of blood sugar control by using fasting blood sugar (FBS) of ≤6.1 mmol/l and glycosyted hemoglobin A1c (HbAc1) of <7% as indictors of glycemic control and to assess the influence of demographic, blood pressure (BP) and lipid characteristics on glycemic control. METHODS:This retrospective s...
journal_title：Primary care diabetes
pub_type： 杂志文章
doi：10.1016/j.pcd.2014.01.003
更新日期：2014-10-01 00:00:00
abstract：:The relative efficacy of different sodium glucose cotransporter 2 (SGLT2) inhibitors and glucagon-like peptide 1 receptor agonists (GLP-1 RAs) in reducing cardiorenal events in type 2 diabetic adults is unclear. We searched PubMed and Embase. Three primary endpoints were major adverse cardiovascular events (MACE), hos...
journal_title：Primary care diabetes
pub_type： 杂志文章
doi：10.1016/j.pcd.2020.08.017
更新日期：2020-09-07 00:00:00
abstract：AIMS:To investigate associations between diabetes distress and productivity, and to identify the potential risk factors that could affect these particular associations. METHODS:This cross-sectional study was conducted in three outpatient healthcare institutions. Patients aged ≥21 years with uncontrolled T2DM and polyp...
journal_title：Primary care diabetes
pub_type： 杂志文章
doi：10.1016/j.pcd.2020.04.004
更新日期：2020-10-01 00:00:00
abstract：OBJECTIVE:The previous study served impaired fasting glucose (IFG), a pre-diabetic state which was much greater than that of diabetic patients, have reached no consensus on its cut-off value. In this study, we aimed to explore the cut-off value of IFG via the associations of blood lipids with fasting plasma glucose (FP...
journal_title：Primary care diabetes
pub_type： 杂志文章
doi：10.1016/j.pcd.2019.07.004
更新日期：2020-04-01 00:00:00
abstract：AIM:To identify risk factors of diabetic retinopathy (DR) among people with Type 2 diabetes mellitus in UK primary care. METHODS:A case-control study nested in a cohort of incident Type 2 diabetes identified in The Health Improvement Network database from 2000 to 2007. Cases were people with DR (N=7735) and controls w...
journal_title：Primary care diabetes
pub_type： 杂志文章
doi：10.1016/j.pcd.2016.01.002
更新日期：2016-08-01 00:00:00
abstract：AIMS:The aim of this study was to evaluate the knowledge about GDM and its corresponding relation with glycaemic level in GDM patients. METHOD:A cross-sectional study was conducted in antenatal clinic of Hospital Pulau Pinang, Malaysia from June 2013 to December 2013 using Gestational Diabetes Mellitus Knowledge Quest...
journal_title：Primary care diabetes
pub_type： 杂志文章
doi：10.1016/j.pcd.2014.07.007
更新日期：2015-06-01 00:00:00
abstract：AIMS:This study aimed to characterize and estimate prevalence and frequency of mild to moderate hypoglycemia and potentially associated factors in a population of type 2 diabetes mellitus (T2DM) patients treated at ambulatory care level. METHODS:HIPOS-PHARMA was a nationwide observational, cross-sectional, multicenter...
journal_title：Primary care diabetes
pub_type： 杂志文章,多中心研究
doi：10.1016/j.pcd.2018.06.001
更新日期：2018-12-01 00:00:00
abstract：AIM:We wanted to investigate third-trimester HbA1c as a predictor of diabetes after gestational diabetes mellitus (GDM). METHODS:Women with GDM were followed up prospectively for five years from pregnancy to detect the development of diabetes. The ability of HbA1c to predict diabetes was evaluated with receiver-operat...
journal_title：Primary care diabetes
pub_type： 杂志文章
doi：10.1016/j.pcd.2016.09.002
更新日期：2017-02-01 00:00:00
abstract：:Over the past decade the UK government has introduced a number of major policy initiatives to improve the quality of health care. One such initiative was the introduction of the Quality and Outcomes Framework (QOF), a pay for performance scheme launched in April 2004, which aims to improve the primary care management ...
journal_title：Primary care diabetes
pub_type： 杂志文章,评审
doi：10.1016/j.pcd.2010.02.003
更新日期：2010-07-01 00:00:00
abstract：OBJECTIVE:The main objective is to examine the effect of the introduction of a practice nurse (PN) on the quality of type 2 diabetes care. METHODS:Retrospective cohort study in 397 type 2 diabetes patients recruited from five general practices in the Netherlands. Measurements were performed in 2003, 2005 and 2007, to ...
journal_title：Primary care diabetes
pub_type： 杂志文章
doi：10.1016/j.pcd.2009.08.003
更新日期：2009-08-01 00:00:00
abstract：AIM:To compare once- versus twice-daily insulin detemir added on OADS therapy in insulin-naive type 2 diabetes patients in terms of efficacy and safety. METHODS:An open-label study performed at a single center, comprised a randomized, crossover 24 week with insulin-naive type 2 diabetes patients. Insulin detemir was i...
journal_title：Primary care diabetes
pub_type： 杂志文章,随机对照试验
doi：10.1016/j.pcd.2014.01.010
更新日期：2014-10-01 00:00:00
abstract：BACKGROUND:Type 2 Diabetes (T2D) continues to be an escalating public health problem contributes to increased morbidity and mortality. Although the complications of T2D is a major threat to the health of women of Arab descent, there is lack of information about their health practices and diabetes self-management behavi...
journal_title：Primary care diabetes
pub_type： 杂志文章
doi：10.1016/j.pcd.2020.10.009
更新日期：2020-11-08 00:00:00
abstract：AIMS:To assess differences in hemoglobin A1c (HbA1c) over time in diabetics treated by internal medicine physicians using the chronic care model (IMP-ancillary) or an advanced practice nurse (APN-IMP). METHODS:Retrospective, 2-group comparative design using administrative databases and matching of IMP-ancillary and AP...
journal_title：Primary care diabetes
pub_type： 杂志文章
doi：10.1016/j.pcd.2018.01.008
更新日期：2018-08-01 00:00:00
abstract：AIMS:The purpose of our investigation was to identify the genetic and clinical risk factors of type 2 diabetes mellitus (T2DM) and to predict the incidence of T2DM in Korean adults aged 40-69 at follow-up intervals of 5, 7, and 10years. METHODS:Korean Genome and Epidemiology Study (KoGES) cohort data (n=10,030) were u...
journal_title：Primary care diabetes
pub_type： 杂志文章
doi：10.1016/j.pcd.2018.07.004
更新日期：2019-02-01 00:00:00
abstract：OBJECTIVES:Novel interventions are needed for long-term maintenance of diabetes control. We studied the effects of a group diabetes clinic (GDC) on diabetes control when compared to usual care with primary care providers (PCP). RESEARCH DESIGN/METHODS:Data from the electronic medical records of 56 patients were collec...
journal_title：Primary care diabetes
pub_type： 杂志文章
doi：10.1016/j.pcd.2010.09.004
更新日期：2010-12-01 00:00:00
abstract：:From the MDI-liraglutide study, we evaluated variables associated with endogenous insulin production in persons with multiple daily insulin injections-treated type 2 diabetes by relating C-peptide, proinsulin and proinsulin/C-peptide ratio at baseline to baseline variables. Lower insulin production was related to long...
journal_title：Primary care diabetes
pub_type： 杂志文章
doi：10.1016/j.pcd.2020.11.005
更新日期：2020-12-07 00:00:00
abstract：BACKGROUND:Diabetes is known as a major cause of morbidity and mortality worldwide. Portugal is known as the European country with the highest prevalence of this disease. While diabetes prevalence data is updated annually in Portugal, the General Practitioner's (GP) Sentinel Network represents the only data source on d...
journal_title：Primary care diabetes
pub_type： 杂志文章
doi：10.1016/j.pcd.2016.05.003
更新日期：2016-10-01 00:00:00
