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The cut-off value of impaired fasting glucose should be lower: Based on the associations of fasting blood glucose with blood lipids.

Abstract：

OBJECTIVE:The previous study served impaired fasting glucose (IFG), a pre-diabetic state which was much greater than that of diabetic patients, have reached no consensus on its cut-off value. In this study, we aimed to explore the cut-off value of IFG via the associations of blood lipids with fasting plasma glucose (FPG). DESIGN:A cross-sectional study in Jilin province, China, 2012. SAMPLE:13,093 participants aged 18-79 years in Jilin province were involved in the study. The Lamba-Mu-Sigma (LMS) method and generalized additive model (GAM) were used to explore the associations of different levels of FPG and blood lipids. RESULTS:The distributions of FPG, triglyceride (TG) and high-density lipoprotein cholesterol (HDL-c) were significantly different by gender (p<0.01). In general, both LMS and GAM results showed that the TG and HDL-c curves had a steeper tendency when the FPG was greater than 6.0mmol/L. CONCLUSION:FPG was positively associated with TG while negatively associated with HDL-c, and the associations were stronger in females. The cut-off value of IFG was suggested to be 6.0mmol/L.

journal_name

Prim Care Diabetes

journal_title

Primary care diabetes

authors

Mengzi S,Min W,Chong S,Pingping Z,Yaogai L,Liyuan P,Shuo L,Yan Y,Lina J

doi

10.1016/j.pcd.2019.07.004

subject

Has Abstract

pub_date

2020-04-01 00:00:00

pages

147-153

issue

2

eissn

1751-9918

issn

1878-0210

pii

S1751-9918(18)30453-4

journal_volume

14

pub_type

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