Abstract:
AIMS:To investigate whether long-term mortality or clinical outcomes differed between patients diagnosed with type 2 diabetes mellitus and presenting with HbA1c within or above normal range at time of diagnosis. METHODS:Data were from a population-based sample of 1136 individuals with newly diagnosed type 2 diabetes mellitus. The diagnosis was confirmed with a single fasting whole blood/plasma glucose ≥7.0/8.0mmol/l. The median time from day of diagnosis until end of follow up was 18.8years. Patients were grouped according to normal HbA1c and elevated HbA1c at diagnosis. The effect of elevated HbA1c on a number of clinical outcomes and all-cause mortality was assessed in Cox regression models. RESULTS:At diagnosis, 97 patients (8.5%) had an HbA1c level within normal range. Age (mean (SD)) at diagnosis was 64.5 (11.5) years. Both unadjusted and adjusted hazard ratios for the effect of HbA1c on mortality and other outcomes were not statistically significant. CONCLUSIONS:Patients who are diagnosed with type 2 diabetes mellitus by means of elevated fasting whole blood/plasma glucose but have HbA1c within reference range at diagnosis do not seem to have a relatively benign long-term clinical course. Therefore new diagnostic procedures should preferably be able to identify these individuals.
journal_name
Prim Care Diabetesjournal_title
Primary care diabetesauthors
Veloso AG,Siersma V,Heldgaard PE,de Fine Olivarius Ndoi
10.1016/j.pcd.2012.09.001subject
Has Abstractpub_date
2013-04-01 00:00:00pages
33-8issue
1eissn
1751-9918issn
1878-0210pii
S1751-9918(12)00107-6journal_volume
7pub_type
杂志文章abstract:AIMS:The aim of this study was to evaluate the knowledge about GDM and its corresponding relation with glycaemic level in GDM patients. METHOD:A cross-sectional study was conducted in antenatal clinic of Hospital Pulau Pinang, Malaysia from June 2013 to December 2013 using Gestational Diabetes Mellitus Knowledge Quest...
journal_title:Primary care diabetes
pub_type: 杂志文章
doi:10.1016/j.pcd.2014.07.007
更新日期:2015-06-01 00:00:00
abstract::Blood pressure management guidelines are widely available. Our aim was to examine differences in blood pressure on the same subjects in primary and secondary care. We identified 661 diabetic subjects with measurements with the aid of the SAIL databank. Blood pressure in primary care was significantly lower than second...
journal_title:Primary care diabetes
pub_type: 杂志文章
doi:10.1016/j.pcd.2009.06.001
更新日期:2009-08-01 00:00:00
abstract:AIM:To investigate the organisation of diabetes care in general practice in Ireland and identify areas for future development. METHODS:Survey of a representative sample of 600 general practitioners (GPs). The questionnaire contained closed and open-ended questions addressing 4 topics; characteristics of the practice, ...
journal_title:Primary care diabetes
pub_type: 杂志文章
doi:10.1016/j.pcd.2009.09.002
更新日期:2009-11-01 00:00:00
abstract:AIMS:The prevalence of Type 2 Diabetes Mellitus among adolescents in the United States continues to rise, following the trajectory of the obesity epidemic which posits not only a substantial health burden to our society, but also a significant threat to the wellbeing of America's youth. While a number of studies have e...
journal_title:Primary care diabetes
pub_type: 杂志文章
doi:10.1016/j.pcd.2020.05.017
更新日期:2021-02-01 00:00:00
abstract:BACKGROUND:The way that GP practices organize their services impacts as much on glycaemia in type 2 diabetes as does prescribing. AIM:Our aim was to evaluate the link between patients' own perception of support within primary care and the % patients at each GP practice at target glycaemic control (TGC) and at high gly...
journal_title:Primary care diabetes
pub_type: 杂志文章,多中心研究
doi:10.1016/j.pcd.2019.04.005
更新日期:2020-02-01 00:00:00
abstract:AIMS:To assess the diagnostic accuracy of the Finnish Diabetes Risk Score (FINDRISC) for undiagnosed T2DM and to compare its performance with the Latin-American FINDRISC (LA-FINDRISC) and the Peruvian Risk Score. MATERIALS AND METHODS:A population-based study was conducted. T2DM and undiagnosed T2DM were defined using...
journal_title:Primary care diabetes
pub_type: 杂志文章
doi:10.1016/j.pcd.2018.07.015
更新日期:2018-12-01 00:00:00
abstract::Insulin detemir provides prolonged, reproducible blood glucose reduction through a mechanism unique among basal insulins. It was originally studied clinically in predominantly basal + bolus regimens and found to be associated with a low risk of hypoglycaemia compared to insulin NPH, and reduced weight gain compared to...
journal_title:Primary care diabetes
pub_type: 历史文章,杂志文章
doi:10.1016/S1751-9918(10)60007-1
更新日期:2010-04-01 00:00:00
abstract:AIMS:People with diabetes have heightened levels of depressive symptoms, but less is known about the development of these symptoms in relation to diabetes duration. In this study, we examined the use of prescribed antidepressants in the first five years after diagnosis of diabetes among the working-age population in De...
journal_title:Primary care diabetes
pub_type: 杂志文章
doi:10.1016/j.pcd.2018.01.002
更新日期:2018-08-01 00:00:00
abstract::Many patients with type 2 diabetes continue to have poor glycaemic control and would benefit from insulin therapy. However, resistance to the introduction of insulin therapy can be high on both the part of the healthcare provider and the patient. A number of new, long-acting basal insulins are in development that prov...
journal_title:Primary care diabetes
pub_type: 杂志文章,评审
doi:10.1016/j.pcd.2013.09.003
更新日期:2014-07-01 00:00:00
abstract:AIMS:To analyze the use of pain medication among community-dwelling people aged 65 years or older with and without type 2 diabetes in primary care. METHODS:A total of 187 patients with and 176 patients without diabetes were randomly selected from a primary care sample of 389 patients with diabetes and 604 age- and gen...
journal_title:Primary care diabetes
pub_type: 杂志文章
doi:10.1016/j.pcd.2020.05.016
更新日期:2020-12-01 00:00:00
abstract:AIM:The aim of the study was to determine factors influencing foot care behaviors among adults with type 2 diabetes. METHODS:A correlational descriptive study was conducted with a random sample of 160 adults with type 2 diabetes from the public hospital between April and July 2014. RESULTS:Just over 15% of the sample...
journal_title:Primary care diabetes
pub_type: 杂志文章
doi:10.1016/j.pcd.2016.04.002
更新日期:2016-12-01 00:00:00
abstract:BACKGROUND:Albuminuria is an early marker of kidney disease in patients with diabetes and/or hypertension undetected or untreated albuminuria is a leading cause of chronic kidney disease and cardiovascular events, The purpose of the present survey was to assess the prevalence of albuminuria in patients with diabetes an...
journal_title:Primary care diabetes
pub_type: 杂志文章
doi:10.1016/j.pcd.2018.08.008
更新日期:2018-12-01 00:00:00
abstract:AIMS:To identify risk factors for falls in older people with diabetes mellitus (DM) and to develop a low-cost fall risk screening tool. METHODS:Older adults with DM (n = 103; age = 61.6 + 6.0 years) were recruited from diabetic clinics. Demographic, DM specific factors, lower limb strength and sensation, cognition, fe...
journal_title:Primary care diabetes
pub_type: 杂志文章
doi:10.1016/j.pcd.2020.05.006
更新日期:2020-12-01 00:00:00
abstract:AIMS:This study investigated (factors related to) (a) the response to a screening procedure for depression and anxiety in people with type 2 diabetes in primary care, and (b) participation in a subsequent randomised controlled trial targeting depressive or anxiety symptoms. METHODS:People with type 2 diabetes (n=1837)...
journal_title:Primary care diabetes
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.pcd.2017.02.006
更新日期:2017-06-01 00:00:00
abstract:AIMS:Chronic low-grade inflammation is closely linked to the development and progression of type 2 diabetes mellitus (T2DM). Since inflammatory markers tend to be chronically elevated in current smokers, we examined the association of inflammatory markers, including leukocyte counts and C-reactive protein (CRP) levels,...
journal_title:Primary care diabetes
pub_type: 杂志文章
doi:10.1016/j.pcd.2020.11.010
更新日期:2020-12-03 00:00:00
abstract:BACKGROUND:Data relating to the association between neck circumference (NC) and metabolic syndrome (MetS) in Southeast Asian population are scarce. AIMS:We aimed to investigate association between NC and MetS in Thai adults, and to determine gender-specific NC cutoff values for predicting MetS. METHODS:This cross-sec...
journal_title:Primary care diabetes
pub_type: 杂志文章
doi:10.1016/j.pcd.2019.08.007
更新日期:2020-06-01 00:00:00
abstract:AIM:To compare the prevalence of psychological distress and mental disorders between diabetes and non-diabetes sufferers and to identify associated factors. METHODS:Case-control study based on data from the 2006 to 2007 Spanish National Health Survey. We identified 2193 type 2 diabetic adults. Non-diabetic controls we...
journal_title:Primary care diabetes
pub_type: 杂志文章
doi:10.1016/j.pcd.2011.10.002
更新日期:2012-07-01 00:00:00
abstract:OBJECTIVE:To examine the prevalence of chronic kidney disease (CKD) and related cardiovascular morbidity in a cross-sectional population in patients with type 2 diabetes (T2D) treated in a primary care setting in Finland. RESEARCH DESIGN AND METHODS:Data were collected and recorded from 42 primary care centres, which ...
journal_title:Primary care diabetes
pub_type: 杂志文章
doi:10.1016/j.pcd.2014.06.001
更新日期:2015-02-01 00:00:00
abstract::HbA1c values are heavily relied on to assess glycemic control. Hemoglobin variants may interfere with measurements of HbA1c resulting in falsely low values. We present the first report of a rare variant of Hb in a patient with type 2 diabetes, which lead to a falsely low HbA1c. ...
journal_title:Primary care diabetes
pub_type: 杂志文章
doi:10.1016/j.pcd.2008.05.003
更新日期:2008-09-01 00:00:00
abstract:AIMS:To describe the diabetic population receiving primary care from the Tshwane district public health services and to assess the quality of care of members of this population, their level of disease control and the extent of their complications. METHODS:A cluster-randomised trial was conducted in 12 primary care cli...
journal_title:Primary care diabetes
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.pcd.2014.05.002
更新日期:2015-04-01 00:00:00
abstract:AIMS:This study aimed to characterize and estimate prevalence and frequency of mild to moderate hypoglycemia and potentially associated factors in a population of type 2 diabetes mellitus (T2DM) patients treated at ambulatory care level. METHODS:HIPOS-PHARMA was a nationwide observational, cross-sectional, multicenter...
journal_title:Primary care diabetes
pub_type: 杂志文章,多中心研究
doi:10.1016/j.pcd.2018.06.001
更新日期:2018-12-01 00:00:00
abstract:OBJECTIVE:The previous study served impaired fasting glucose (IFG), a pre-diabetic state which was much greater than that of diabetic patients, have reached no consensus on its cut-off value. In this study, we aimed to explore the cut-off value of IFG via the associations of blood lipids with fasting plasma glucose (FP...
journal_title:Primary care diabetes
pub_type: 杂志文章
doi:10.1016/j.pcd.2019.07.004
更新日期:2020-04-01 00:00:00
abstract::There are several tools for the assessment of quality of life (QOL) in diabetes mellitus. In the current research, two standard questionnaires for evaluating of QOL were selected. First one was a questionnaire from the World Health Organization quality of life (WHOQOL-BREF 26) and the second one, The Iranian diabetics...
journal_title:Primary care diabetes
pub_type: 杂志文章
doi:10.1016/j.pcd.2011.02.001
更新日期:2011-07-01 00:00:00
abstract:AIMS:We investigated to clarify factors associated with the efficacy of sitagliptin, a dipeptidyl peptidase (DPP)-IV inhibitor, for glycemic control including the confounding effect of concomitant drugs in patients with type 2 diabetes. METHODS:We included type 2 diabetes patients with HbA1c levels of ≥7% who were not...
journal_title:Primary care diabetes
pub_type: 杂志文章,多中心研究
doi:10.1016/j.pcd.2014.01.008
更新日期:2014-10-01 00:00:00
abstract::Exenatide use in type 2 diabetes is limited in routine clinical practice. We examined a cross-section of 90 patients. Mean weight and HBA(1c) were 114.9+/-20.6 kg, 10.3+/-2.1% at initiation; 108.0+/-15.3 kg (p<0.0001), 9.0+/-2.1% (p<0.001) at 3 months; 109.2+/-18.2 kg (p<0.0001), 9.5+/-2.3% (p=0.08) at 6 months. Exena...
journal_title:Primary care diabetes
pub_type: 杂志文章
doi:10.1016/j.pcd.2009.11.001
更新日期:2010-04-01 00:00:00
abstract:AIMS:The purpose of our investigation was to identify the genetic and clinical risk factors of type 2 diabetes mellitus (T2DM) and to predict the incidence of T2DM in Korean adults aged 40-69 at follow-up intervals of 5, 7, and 10years. METHODS:Korean Genome and Epidemiology Study (KoGES) cohort data (n=10,030) were u...
journal_title:Primary care diabetes
pub_type: 杂志文章
doi:10.1016/j.pcd.2018.07.004
更新日期:2019-02-01 00:00:00
abstract:AIMS:To assess perceptions surrounding diabetes self-management (DSM) behaviors in Arab American patients with diabetes. METHODS:A 39-item survey was constructed from focus group discussions designed to better understand the impact of Arab American culture on DSM behaviors. The survey assessed perceptions about diet, ...
journal_title:Primary care diabetes
pub_type: 杂志文章
doi:10.1016/j.pcd.2019.09.002
更新日期:2020-06-01 00:00:00
abstract::Our study demonstrates that Ipswich Touch Test is reliable and comparable to established standardized tests that identify the risk of foot ulceration among Saudi patients with diabetes mellitus. The simplicity of the test will assist in overcoming the barriers to screen for and detect the risk of foot ulceration. ...
journal_title:Primary care diabetes
pub_type: 杂志文章
doi:10.1016/j.pcd.2014.10.007
更新日期:2015-08-01 00:00:00
abstract:OBJECTIVES:Novel interventions are needed for long-term maintenance of diabetes control. We studied the effects of a group diabetes clinic (GDC) on diabetes control when compared to usual care with primary care providers (PCP). RESEARCH DESIGN/METHODS:Data from the electronic medical records of 56 patients were collec...
journal_title:Primary care diabetes
pub_type: 杂志文章
doi:10.1016/j.pcd.2010.09.004
更新日期:2010-12-01 00:00:00
abstract::Diabetes (DM) and its resultant complications are a problem worldwide, and especially in developing countries like South Africa (SA). Risk factors associated with DM are potentially modifiable, but DM control is poor. Problems in SA include high prevalence of morbidity from DM and hypertension (HTN), lack of recogniti...
journal_title:Primary care diabetes
pub_type: 杂志文章
doi:10.1016/j.pcd.2009.06.007
更新日期:2009-08-01 00:00:00