Abstract:
OBJECTIVE:To examine the prevalence of chronic kidney disease (CKD) and related cardiovascular morbidity in a cross-sectional population in patients with type 2 diabetes (T2D) treated in a primary care setting in Finland. RESEARCH DESIGN AND METHODS:Data were collected and recorded from 42 primary care centres, which recruited 629 patients diagnosed with type 2 diabetes (T2D) to this non-interventional study. Data including patient characteristics, kidney function and albuminuria, blood pressure, HbA1c, lipid and lipoprotein levels, and diabetes duration as well as current medication was collected in each patient. RESULTS:In the final study population of 625 patients, the mean age was 67 years (range 29-92 years), BMI 32.8 kg/m(2) (95% CI 32-33), blood pressure 142/80 mmHg (140-143/80-81) and HbA1c 7.1% (7.0-7.2) (53.8 mmol/mol, 53-55) and the median duration of diabetes was 9.2 years ranging from newly diagnosed to 43 years. History of dyslipidemia had in 73.3% of patients, 27.8% had cardiovascular disease and 82.7% had hypertension. The primary endpoint, prevalence of CKD of any grade (1-5) or albuminuria, was 68.6%. Regarding declined renal function, 16.2% of patients had an estimated glomerular filtration rate (eGFR) <60 ml/min/1.72 m(2), classifying as CKD 3-5. Only one patient was within CKD5. Regarding renal damage, albuminuria was present in 24.3% of patients, with microalbuminuria in 17.1% and macroalbuminuria in 7.2%, respectively. Combining the patients with CKD 3-5 and/or the presence of albuminuria, 34.7% seemed to suffer from significant CKD. The proportion of patients with albuminuria increased with a decrease in glomerular filtration rate. Historically, diabetic nephropathy had been diagnosed in 24.3% of the patients. CONCLUSIONS:Nearly 70% of patients with T2D treated in primary care in Finland have some sign of CKD and nearly half of all T2D patients have a significant CKD. However, only half of the latter had it diagnosed and documented in their patient charts, thus highlighting the importance of performing routine screening of nephropathy by measuring both albuminuria and eGFR in patients with T2D. Prevention of this complication with active therapy for risk factors, such as hypertension and dyslipidemia is warranted.
journal_name
Prim Care Diabetesjournal_title
Primary care diabetesauthors
Metsärinne K,Bröijersen A,Kantola I,Niskanen L,Rissanen A,Appelroth T,Pöntynen N,Poussa T,Koivisto V,Virkamäki A,STages of NEphropathy inType 2 Diabetes Study Investigators.doi
10.1016/j.pcd.2014.06.001subject
Has Abstractpub_date
2015-02-01 00:00:00pages
31-8issue
1eissn
1751-9918issn
1878-0210pii
S1751-9918(14)00072-2journal_volume
9pub_type
杂志文章abstract:BACKGROUND:The way that GP practices organize their services impacts as much on glycaemia in type 2 diabetes as does prescribing. AIM:Our aim was to evaluate the link between patients' own perception of support within primary care and the % patients at each GP practice at target glycaemic control (TGC) and at high gly...
journal_title:Primary care diabetes
pub_type: 杂志文章,多中心研究
doi:10.1016/j.pcd.2019.04.005
更新日期:2020-02-01 00:00:00
abstract:AIMS:Chronic low-grade inflammation is closely linked to the development and progression of type 2 diabetes mellitus (T2DM). Since inflammatory markers tend to be chronically elevated in current smokers, we examined the association of inflammatory markers, including leukocyte counts and C-reactive protein (CRP) levels,...
journal_title:Primary care diabetes
pub_type: 杂志文章
doi:10.1016/j.pcd.2020.11.010
更新日期:2020-12-03 00:00:00
abstract:AIMS:The goal of this retrospective cohort study was to analyze the incidence of, and factors associated with the antiepileptic drug (AED) therapy in the five years following the diagnosis of diabetic polyneuropathy in patients followed in Germany. METHODS:The study included patients aged 18-80 years with an initial d...
journal_title:Primary care diabetes
pub_type: 杂志文章
doi:10.1016/j.pcd.2020.12.005
更新日期:2021-01-06 00:00:00
abstract:AIMS:To evaluate the degree of glycemic control and its relationship with disease characteristics and antidiabetic treatment in patients with type 2 diabetes mellitus (DM), as well as the frequency of A1c use. METHODS:For this purpose, an observational, cross-sectorial, and multicenter study was performed. A total of ...
journal_title:Primary care diabetes
pub_type: 杂志文章,多中心研究
doi:10.1016/j.pcd.2015.01.006
更新日期:2015-10-01 00:00:00
abstract:AIMS:The prevalence of Type 2 Diabetes Mellitus among adolescents in the United States continues to rise, following the trajectory of the obesity epidemic which posits not only a substantial health burden to our society, but also a significant threat to the wellbeing of America's youth. While a number of studies have e...
journal_title:Primary care diabetes
pub_type: 杂志文章
doi:10.1016/j.pcd.2020.05.017
更新日期:2021-02-01 00:00:00
abstract:BACKGROUND:The influenza virus is an important cause of morbidity and mortality for diabetics. The seasonal influenza vaccine's immunologic effectiveness is proven within the type 1 and type 2 diabetic populations, but the level of evidence is low. This article presents a systematic review for the bias in the measure o...
journal_title:Primary care diabetes
pub_type: 杂志文章,评审
doi:10.1016/j.pcd.2016.05.005
更新日期:2016-12-01 00:00:00
abstract:AIM:To compare once- versus twice-daily insulin detemir added on OADS therapy in insulin-naive type 2 diabetes patients in terms of efficacy and safety. METHODS:An open-label study performed at a single center, comprised a randomized, crossover 24 week with insulin-naive type 2 diabetes patients. Insulin detemir was i...
journal_title:Primary care diabetes
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.pcd.2014.01.010
更新日期:2014-10-01 00:00:00
abstract:AIMS:To assess to which extent lowering the level of HbA1c influences the 10-year risk of coronary heart disease (CHD) and all-cause mortality in patients with type 2 diabetes mellitus. METHODS:A literature search in Pubmed and Embase was performed, and the absolute risks in the results of the relevant and valid studi...
journal_title:Primary care diabetes
pub_type: 杂志文章,评审
doi:10.1016/j.pcd.2007.12.004
更新日期:2008-02-01 00:00:00
abstract:OBJECTIVE:The aim of this research study was to ascertain the awareness of Maltese family doctors to the prevalence and significance of impaired glucose regulation and early diagnosis of type 2 diabetes and whether practices were influenced by employment status, post-graduate training in diabetes or years since graduat...
journal_title:Primary care diabetes
pub_type: 杂志文章
doi:10.1016/j.pcd.2013.12.003
更新日期:2014-10-01 00:00:00
abstract:BACKGROUND:Diabetes is especially common in the United Arab Emirates. Its complications in patients residing in the region have yet to be fully explored. This study reports on foot problems in our diabetic patients, with emphasis on the impact of illiteracy on foot care and complications due to diabetes. METHODS:Adult...
journal_title:Primary care diabetes
pub_type: 杂志文章
doi:10.1016/j.pcd.2015.04.008
更新日期:2015-12-01 00:00:00
abstract:AIMS:To evaluate the incidence and risk factors for carotid artery stenosis amongst asymptomatic type 2 diabetes from a single Malaysian tertiary institution. METHODS:This is a prospective cross-sectional study of asymptomatic type 2 diabetics selected from the outpatient ophthalmology and endocrine clinics for caroti...
journal_title:Primary care diabetes
pub_type: 杂志文章
doi:10.1016/j.pcd.2019.10.001
更新日期:2020-08-01 00:00:00
abstract:AIMS:This study investigates whether diabetes patients visiting a primary care setting are interested in using a telemonitoring platform and if so, whether characteristics of interested users could be distinguished. METHODS:Three questionnaires were administered by 92 diabetes persons recruited between May and Septemb...
journal_title:Primary care diabetes
pub_type: 杂志文章
doi:10.1016/j.pcd.2012.10.085
更新日期:2013-07-01 00:00:00
abstract:AIMS:To investigate associations between diabetes distress and productivity, and to identify the potential risk factors that could affect these particular associations. METHODS:This cross-sectional study was conducted in three outpatient healthcare institutions. Patients aged ≥21 years with uncontrolled T2DM and polyp...
journal_title:Primary care diabetes
pub_type: 杂志文章
doi:10.1016/j.pcd.2020.04.004
更新日期:2020-10-01 00:00:00
abstract:BACKGROUND:Data relating to the association between neck circumference (NC) and metabolic syndrome (MetS) in Southeast Asian population are scarce. AIMS:We aimed to investigate association between NC and MetS in Thai adults, and to determine gender-specific NC cutoff values for predicting MetS. METHODS:This cross-sec...
journal_title:Primary care diabetes
pub_type: 杂志文章
doi:10.1016/j.pcd.2019.08.007
更新日期:2020-06-01 00:00:00
abstract:AIMS:This study aimed to investigate the prevalence of restless leg syndrome (RLS) in type-2 diabetes mellitus (DM) patients and to determine the risk factors. METHODS:Patients were recruited from the Dr. Lütfi Kırdar Kartal Training and Research Hospital Diabetes Center. Patients between 18-80 years of age and meetin...
journal_title:Primary care diabetes
pub_type: 杂志文章
doi:10.1016/j.pcd.2018.08.006
更新日期:2019-02-01 00:00:00
abstract:AIMS:To assess changes over two years in the health status and management of a cohort of people with Type 2 diabetes from different ethnic groups within a primary care diabetes annual review programme in New Zealand. METHODS:The study evaluated changes in clinical measures and proportions achieving guideline targets f...
journal_title:Primary care diabetes
pub_type: 杂志文章
doi:10.1016/j.pcd.2008.08.002
更新日期:2008-12-01 00:00:00
abstract:AIMS:This study investigated (factors related to) (a) the response to a screening procedure for depression and anxiety in people with type 2 diabetes in primary care, and (b) participation in a subsequent randomised controlled trial targeting depressive or anxiety symptoms. METHODS:People with type 2 diabetes (n=1837)...
journal_title:Primary care diabetes
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.pcd.2017.02.006
更新日期:2017-06-01 00:00:00
abstract:AIMS:To study the frequency and intensity of depressive symptoms and associations with physician resource utilisation following insulin initiation in patients with type 2 diabetes mellitus. METHODS:SOLVE was a 24-week observational study. In this sub-analysis of data from Poland, depressive symptoms were evaluated usi...
journal_title:Primary care diabetes
pub_type: 杂志文章
doi:10.1016/j.pcd.2015.01.002
更新日期:2015-10-01 00:00:00
abstract:AIM:We wanted to investigate third-trimester HbA1c as a predictor of diabetes after gestational diabetes mellitus (GDM). METHODS:Women with GDM were followed up prospectively for five years from pregnancy to detect the development of diabetes. The ability of HbA1c to predict diabetes was evaluated with receiver-operat...
journal_title:Primary care diabetes
pub_type: 杂志文章
doi:10.1016/j.pcd.2016.09.002
更新日期:2017-02-01 00:00:00
abstract:AIMS:To evaluate the impact of the integration of onsite diabetes education teams in primary care on processes of care indicators according to practice guidelines. METHODS:Teams of nurse and dietitian educators delivered individualized self-management education counseling in 11 Ontario primary care sites. Of the 771 a...
journal_title:Primary care diabetes
pub_type: 杂志文章
doi:10.1016/j.pcd.2019.06.004
更新日期:2020-04-01 00:00:00
abstract::Our study demonstrates that Ipswich Touch Test is reliable and comparable to established standardized tests that identify the risk of foot ulceration among Saudi patients with diabetes mellitus. The simplicity of the test will assist in overcoming the barriers to screen for and detect the risk of foot ulceration. ...
journal_title:Primary care diabetes
pub_type: 杂志文章
doi:10.1016/j.pcd.2014.10.007
更新日期:2015-08-01 00:00:00
abstract:INTRODUCTION:Diabetes knowledge has a large impact on glycemic control. There is a pressing need for creation of validated tests of knowledge for different ethnic groups. OBJECTIVE:To create and validate a diabetes knowledge test (DKT) for young Indians with type 1 diabetes mellitus (T1DM). METHODS:We created a 34 it...
journal_title:Primary care diabetes
pub_type: 杂志文章
doi:10.1016/j.pcd.2018.12.001
更新日期:2019-06-01 00:00:00
abstract:AIM:In the current study the relationship between self-reported nocturnal sleep duration (NSD) and daytime sleepiness with 24-h urinary protein excretion (UPE) and 24-h urinary albumin excretion (UAE) were investigated in patients with newly diagnosed type 2 diabetes mellitus. METHODS:All patients underwent history ta...
journal_title:Primary care diabetes
pub_type: 杂志文章
doi:10.1016/j.pcd.2013.01.002
更新日期:2013-04-01 00:00:00
abstract::Exenatide use in type 2 diabetes is limited in routine clinical practice. We examined a cross-section of 90 patients. Mean weight and HBA(1c) were 114.9+/-20.6 kg, 10.3+/-2.1% at initiation; 108.0+/-15.3 kg (p<0.0001), 9.0+/-2.1% (p<0.001) at 3 months; 109.2+/-18.2 kg (p<0.0001), 9.5+/-2.3% (p=0.08) at 6 months. Exena...
journal_title:Primary care diabetes
pub_type: 杂志文章
doi:10.1016/j.pcd.2009.11.001
更新日期:2010-04-01 00:00:00
abstract::Blood pressure management guidelines are widely available. Our aim was to examine differences in blood pressure on the same subjects in primary and secondary care. We identified 661 diabetic subjects with measurements with the aid of the SAIL databank. Blood pressure in primary care was significantly lower than second...
journal_title:Primary care diabetes
pub_type: 杂志文章
doi:10.1016/j.pcd.2009.06.001
更新日期:2009-08-01 00:00:00
abstract:OBJECTIVE:The main objective is to examine the effect of the introduction of a practice nurse (PN) on the quality of type 2 diabetes care. METHODS:Retrospective cohort study in 397 type 2 diabetes patients recruited from five general practices in the Netherlands. Measurements were performed in 2003, 2005 and 2007, to ...
journal_title:Primary care diabetes
pub_type: 杂志文章
doi:10.1016/j.pcd.2009.08.003
更新日期:2009-08-01 00:00:00
abstract:BACKGROUND:Type 2 Diabetes (T2D) continues to be an escalating public health problem contributes to increased morbidity and mortality. Although the complications of T2D is a major threat to the health of women of Arab descent, there is lack of information about their health practices and diabetes self-management behavi...
journal_title:Primary care diabetes
pub_type: 杂志文章
doi:10.1016/j.pcd.2020.10.009
更新日期:2020-11-08 00:00:00
abstract:AIM:To compare the prevalence of psychological distress and mental disorders between diabetes and non-diabetes sufferers and to identify associated factors. METHODS:Case-control study based on data from the 2006 to 2007 Spanish National Health Survey. We identified 2193 type 2 diabetic adults. Non-diabetic controls we...
journal_title:Primary care diabetes
pub_type: 杂志文章
doi:10.1016/j.pcd.2011.10.002
更新日期:2012-07-01 00:00:00
abstract:AIMS:To assess perceptions surrounding diabetes self-management (DSM) behaviors in Arab American patients with diabetes. METHODS:A 39-item survey was constructed from focus group discussions designed to better understand the impact of Arab American culture on DSM behaviors. The survey assessed perceptions about diet, ...
journal_title:Primary care diabetes
pub_type: 杂志文章
doi:10.1016/j.pcd.2019.09.002
更新日期:2020-06-01 00:00:00
abstract:OBJECTIVE:Realise a review of studies of economic evaluation about the ambulatory monitoring of capillary glucose (AMGC) in diabetic type II persons. METHODOLOGY:A review of the literature was conducted, in MedLine, various websites, referenced paper and provided by expert's persons. RESULTS:Five studies concluded th...
journal_title:Primary care diabetes
pub_type: 杂志文章,评审
doi:10.1016/j.pcd.2013.11.005
更新日期:2014-04-01 00:00:00