Abstract：
AIMS:The goal of this retrospective cohort study was to analyze the incidence of, and factors associated with the antiepileptic drug (AED) therapy in the five years following the diagnosis of diabetic polyneuropathy in patients followed in Germany. METHODS:The study included patients aged 18-80 years with an initial diagnosis of diabetic polyneuropathy in 1238 general and diabetologist practices in Germany between January 2008 and December 2017 (index date). The main outcome of the study was the incidence of the AED therapy in the five years following the diagnosis of diabetic polyneuropathy. Adjusted Cox regression analyses were conducted to investigate the association between study covariates and the incidence of the AED therapy. RESULTS:The present study included 48,324 patients (mean [standard deviation] age 65.8 [10.6] years, 55.6% male). Within five years of the diagnosis of diabetic polyneuropathy, 16.4% of patients were prescribed at least one AED. The three most frequent drugs were pregabalin, gabapentin, and carbamazepine. Female sex (HR = 1.22), private health insurance coverage (HR = 1.22), follow-up in a general practice (HR = 1.85), HbA1c ≥10% (HR = 1.36), previous referral to a neurological practice (HR = 1.47), previous hospital admission (HR = 1.51) and depression (HR = 1.15) were positively associated with the incidence of the AED therapy. CONCLUSIONS:The incidence of the AED therapy was low in patients recently diagnosed with diabetic polyneuropathy in Germany. More research is warranted to understand the infrequent use of AEDs in diabetic polyneuropathy patients from this country.
journal_name
Prim Care Diabetesjournal_title
Primary care diabetesauthors
Jacob L,Kaiser M,Kostev Kdoi
10.1016/j.pcd.2020.12.005subject
Has Abstractpub_date
2021-01-06 00:00:00eissn
1751-9918issn
1878-0210pii
S1751-9918(20)30364-8pub_type
杂志文章abstract：AIMS:Was to determine whether the birth weight of the infant predicts prediabetes (impaired fasting glucose, impaired glucose tolerance, or both) and type 2 diabetes (T2DM) during long-term follow-up of women with or without gestational diabetes mellitus (GDM). METHODS:The women with or without GDM during their pregna...
journal_title：Primary care diabetes
pub_type： 杂志文章
doi：10.1016/j.pcd.2018.04.002
更新日期：2018-08-01 00:00:00
abstract：AIMS:Incidence of type 1 diabetes mellitus (T1DM) is increasing worldwide. We aimed to study trends in presentation and incidence of childhood diabetes in the last 15years in south-western Iran. METHODS:During a detailed review of compiled records of the main tertiary children's hospital of southwest of Iran, from Jan...
journal_title：Primary care diabetes
pub_type： 杂志文章
doi：10.1016/j.pcd.2018.07.013
更新日期：2019-02-01 00:00:00
abstract：AIM:To investigate the organisation of diabetes care in general practice in Ireland and identify areas for future development. METHODS:Survey of a representative sample of 600 general practitioners (GPs). The questionnaire contained closed and open-ended questions addressing 4 topics; characteristics of the practice, ...
journal_title：Primary care diabetes
pub_type： 杂志文章
doi：10.1016/j.pcd.2009.09.002
更新日期：2009-11-01 00:00:00
abstract：:HbA1c values are heavily relied on to assess glycemic control. Hemoglobin variants may interfere with measurements of HbA1c resulting in falsely low values. We present the first report of a rare variant of Hb in a patient with type 2 diabetes, which lead to a falsely low HbA1c. ...
journal_title：Primary care diabetes
pub_type： 杂志文章
doi：10.1016/j.pcd.2008.05.003
更新日期：2008-09-01 00:00:00
abstract：AIMS:We investigated to clarify factors associated with the efficacy of sitagliptin, a dipeptidyl peptidase (DPP)-IV inhibitor, for glycemic control including the confounding effect of concomitant drugs in patients with type 2 diabetes. METHODS:We included type 2 diabetes patients with HbA1c levels of ≥7% who were not...
journal_title：Primary care diabetes
pub_type： 杂志文章,多中心研究
doi：10.1016/j.pcd.2014.01.008
更新日期：2014-10-01 00:00:00
abstract：OBJECTIVE:The objective of this observational open label trial was to characterize changes in diabetes self-management and psychological distress associated with a mobile health (mHealth) interactive voice response (IVR) self-management support program. METHODS:For 3-6 months, 301 patients with diabetes received weekl...
journal_title：Primary care diabetes
pub_type： 杂志文章
doi：10.1016/j.pcd.2014.06.003
更新日期：2015-04-01 00:00:00
abstract：OBJECTIVE:The aim of this research study was to ascertain the awareness of Maltese family doctors to the prevalence and significance of impaired glucose regulation and early diagnosis of type 2 diabetes and whether practices were influenced by employment status, post-graduate training in diabetes or years since graduat...
journal_title：Primary care diabetes
pub_type： 杂志文章
doi：10.1016/j.pcd.2013.12.003
更新日期：2014-10-01 00:00:00
abstract：:Our study demonstrates that Ipswich Touch Test is reliable and comparable to established standardized tests that identify the risk of foot ulceration among Saudi patients with diabetes mellitus. The simplicity of the test will assist in overcoming the barriers to screen for and detect the risk of foot ulceration. ...
journal_title：Primary care diabetes
pub_type： 杂志文章
doi：10.1016/j.pcd.2014.10.007
更新日期：2015-08-01 00:00:00
abstract：PURPOSE:The aim of this study was to analyze the mortality trends of diabetes mellitus in Serbia (excluding the Autonomous Province of Kosovo and Metohia). METHODS:A population-based cross sectional study analyzing diabetes mortality in Serbia in the period 1991-2015 was carried out based on official data. The age-sta...
journal_title：Primary care diabetes
pub_type： 杂志文章
doi：10.1016/j.pcd.2016.08.019
更新日期：2017-02-01 00:00:00
abstract：BACKGROUND:Diabetes is especially common in the United Arab Emirates. Its complications in patients residing in the region have yet to be fully explored. This study reports on foot problems in our diabetic patients, with emphasis on the impact of illiteracy on foot care and complications due to diabetes. METHODS:Adult...
journal_title：Primary care diabetes
pub_type： 杂志文章
doi：10.1016/j.pcd.2015.04.008
更新日期：2015-12-01 00:00:00
abstract：BACKGROUND:The incidence of type 2 diabetes (T2DM) is increasing. Having a pregnancy complicated by gestational diabetes mellitus (GDM) is a potent risk factor for the later development of T2DM. AIMS:To explore the characteristics of women diagnosed with GDM in a single centre and their follow up for progression to T2...
journal_title：Primary care diabetes
pub_type： 杂志文章
doi：10.1016/j.pcd.2020.05.010
更新日期：2020-12-01 00:00:00
abstract：OBJECTIVE:The main objective is to examine the effect of the introduction of a practice nurse (PN) on the quality of type 2 diabetes care. METHODS:Retrospective cohort study in 397 type 2 diabetes patients recruited from five general practices in the Netherlands. Measurements were performed in 2003, 2005 and 2007, to ...
journal_title：Primary care diabetes
pub_type： 杂志文章
doi：10.1016/j.pcd.2009.08.003
更新日期：2009-08-01 00:00:00
abstract：AIMS:The prevalence of Type 2 Diabetes Mellitus among adolescents in the United States continues to rise, following the trajectory of the obesity epidemic which posits not only a substantial health burden to our society, but also a significant threat to the wellbeing of America's youth. While a number of studies have e...
journal_title：Primary care diabetes
pub_type： 杂志文章
doi：10.1016/j.pcd.2020.05.017
更新日期：2021-02-01 00:00:00
abstract：AIMS:To evaluate the impact of the integration of onsite diabetes education teams in primary care on processes of care indicators according to practice guidelines. METHODS:Teams of nurse and dietitian educators delivered individualized self-management education counseling in 11 Ontario primary care sites. Of the 771 a...
journal_title：Primary care diabetes
pub_type： 杂志文章
doi：10.1016/j.pcd.2019.06.004
更新日期：2020-04-01 00:00:00
abstract：AIMS:To analyze the use of pain medication among community-dwelling people aged 65 years or older with and without type 2 diabetes in primary care. METHODS:A total of 187 patients with and 176 patients without diabetes were randomly selected from a primary care sample of 389 patients with diabetes and 604 age- and gen...
journal_title：Primary care diabetes
pub_type： 杂志文章
doi：10.1016/j.pcd.2020.05.016
更新日期：2020-12-01 00:00:00
abstract：AIMS:To investigate associations between diabetes distress and productivity, and to identify the potential risk factors that could affect these particular associations. METHODS:This cross-sectional study was conducted in three outpatient healthcare institutions. Patients aged ≥21 years with uncontrolled T2DM and polyp...
journal_title：Primary care diabetes
pub_type： 杂志文章
doi：10.1016/j.pcd.2020.04.004
更新日期：2020-10-01 00:00:00
abstract：:Diabetes mellitus (DM) is a frequent disorder affecting individuals of all ages. Glycohemoglobin (GHb) has a key role in the assessment of glycemic control in diabetic patients. Generally, GHb is measured as hemoglobin (Hb) A1C and is the result of an irreversible non-enzymatic glycation of the beta chain of hemoglobi...
journal_title：Primary care diabetes
pub_type： 杂志文章,评审
doi：10.1016/j.pcd.2007.07.004
更新日期：2007-09-01 00:00:00
abstract：AIM:The aim of the study was to determine factors influencing foot care behaviors among adults with type 2 diabetes. METHODS:A correlational descriptive study was conducted with a random sample of 160 adults with type 2 diabetes from the public hospital between April and July 2014. RESULTS:Just over 15% of the sample...
journal_title：Primary care diabetes
pub_type： 杂志文章
doi：10.1016/j.pcd.2016.04.002
更新日期：2016-12-01 00:00:00
abstract：BACKGROUND:Diabetes is known as a major cause of morbidity and mortality worldwide. Portugal is known as the European country with the highest prevalence of this disease. While diabetes prevalence data is updated annually in Portugal, the General Practitioner's (GP) Sentinel Network represents the only data source on d...
journal_title：Primary care diabetes
pub_type： 杂志文章
doi：10.1016/j.pcd.2016.05.003
更新日期：2016-10-01 00:00:00
abstract：OBJECTIVES:Novel interventions are needed for long-term maintenance of diabetes control. We studied the effects of a group diabetes clinic (GDC) on diabetes control when compared to usual care with primary care providers (PCP). RESEARCH DESIGN/METHODS:Data from the electronic medical records of 56 patients were collec...
journal_title：Primary care diabetes
pub_type： 杂志文章
doi：10.1016/j.pcd.2010.09.004
更新日期：2010-12-01 00:00:00
abstract：AIMS:To evaluate the incidence and risk factors for carotid artery stenosis amongst asymptomatic type 2 diabetes from a single Malaysian tertiary institution. METHODS:This is a prospective cross-sectional study of asymptomatic type 2 diabetics selected from the outpatient ophthalmology and endocrine clinics for caroti...
journal_title：Primary care diabetes
pub_type： 杂志文章
doi：10.1016/j.pcd.2019.10.001
更新日期：2020-08-01 00:00:00
abstract：BACKGROUND:Albuminuria is an early marker of kidney disease in patients with diabetes and/or hypertension undetected or untreated albuminuria is a leading cause of chronic kidney disease and cardiovascular events, The purpose of the present survey was to assess the prevalence of albuminuria in patients with diabetes an...
journal_title：Primary care diabetes
pub_type： 杂志文章
doi：10.1016/j.pcd.2018.08.008
更新日期：2018-12-01 00:00:00
abstract：AIMS:To identify factors associated with patients receiving foot examinations by primary health care nurses. METHODS:A cross-sectional survey of 287 randomly sampled primary health care nurses, from a total of 1091 in Auckland, completed a postal self-administered questionnaire and telephone interview. Biographical an...
journal_title：Primary care diabetes
pub_type： 杂志文章
doi：10.1016/j.pcd.2013.10.002
更新日期：2014-07-01 00:00:00
abstract：:Many patients with type 2 diabetes continue to have poor glycaemic control and would benefit from insulin therapy. However, resistance to the introduction of insulin therapy can be high on both the part of the healthcare provider and the patient. A number of new, long-acting basal insulins are in development that prov...
journal_title：Primary care diabetes
pub_type： 杂志文章,评审
doi：10.1016/j.pcd.2013.09.003
更新日期：2014-07-01 00:00:00
abstract：OBJECTIVE:To assess the prevalence of Graves' disease in patients with type 1 diabetes mellitus all coming from a defined geographical area (western Sicily-Italy) and to investigate the clinical features of these subjects. METHODS:The records of 470 consecutive patients with type 1 diabetes mellitus referred in a 5-ye...
journal_title：Primary care diabetes
pub_type： 杂志文章
doi：10.1016/j.pcd.2011.06.001
更新日期：2011-12-01 00:00:00
abstract：OBJECTIVE:To examine the prevalence of chronic kidney disease (CKD) and related cardiovascular morbidity in a cross-sectional population in patients with type 2 diabetes (T2D) treated in a primary care setting in Finland. RESEARCH DESIGN AND METHODS:Data were collected and recorded from 42 primary care centres, which ...
journal_title：Primary care diabetes
pub_type： 杂志文章
doi：10.1016/j.pcd.2014.06.001
更新日期：2015-02-01 00:00:00
abstract：AIMS:This study investigates whether diabetes patients visiting a primary care setting are interested in using a telemonitoring platform and if so, whether characteristics of interested users could be distinguished. METHODS:Three questionnaires were administered by 92 diabetes persons recruited between May and Septemb...
journal_title：Primary care diabetes
pub_type： 杂志文章
doi：10.1016/j.pcd.2012.10.085
更新日期：2013-07-01 00:00:00
abstract：AIM:This paper determines whether patients with and without Diabetic Peripheral Neuropathy use suitable footwear, taking into account that these persons are subject to a significant loss of sensitivity in the feet. METHODS:Cross-sectional observational study was conducted of 108 participants with diabetes mellitus. In...
journal_title：Primary care diabetes
pub_type： 杂志文章
doi：10.1016/j.pcd.2020.08.009
更新日期：2021-02-01 00:00:00
abstract：AIMS:Chronic low-grade inflammation is closely linked to the development and progression of type 2 diabetes mellitus (T2DM). Since inflammatory markers tend to be chronically elevated in current smokers, we examined the association of inflammatory markers, including leukocyte counts and C-reactive protein (CRP) levels,...
journal_title：Primary care diabetes
pub_type： 杂志文章
doi：10.1016/j.pcd.2020.11.010
更新日期：2020-12-03 00:00:00
abstract：AIM:To investigate if micro- and macrovascular co-morbidity has an influence on the time to insulin initiation in type 2 diabetes patients. METHODS:Longitudinal data from general practices in Germany, France and UK (Disease Analyzer) from 1995 to 2009 were analyzed, including 44,440 patients in Germany, 10,148 patient...
journal_title：Primary care diabetes
pub_type： 杂志文章,多中心研究
doi：10.1016/j.pcd.2013.02.001
更新日期：2013-07-01 00:00:00
