Abstract：
AIMS:To study the frequency and intensity of depressive symptoms and associations with physician resource utilisation following insulin initiation in patients with type 2 diabetes mellitus. METHODS:SOLVE was a 24-week observational study. In this sub-analysis of data from Poland, depressive symptoms were evaluated using the Patient Health Questionnaire (PHQ)-9. RESULTS:PHQ-9 was completed by 942 of 1169 patients (80.6%) at baseline, and 751 (64.2%) at both baseline and final (24-week) visit. PHQ-9 scores indicated depressive symptoms in 45.6% (n=430) at baseline, and 27.2% (n=223) at final visit. Mean PHQ-9 change was -2.38 [95% CI -2.73, -2.02], p<0.001. Depressive symptoms at baseline (OR 6.32, p<0.001), microvascular disease (OR 2.45, p=0.016), number of physician contacts (OR 1.16, p=0.009), and change in HbA1c (OR 0.60, p=0.025) were independently associated with moderate/severe depressive symptoms at final visit. Patients with more severe depressive symptoms spent more time training to self-inject (p=0.0016), self-adjust (p=0.0023) and manage other aspects of insulin delivery (p<0.0001). Patients with persistent depressive symptoms had more telephone contacts and dose changes at final visit than those without (both p<0.05). CONCLUSIONS:Depressive symptoms are common with type 2 diabetes and associated with increased healthcare utilisation, reinforcing the need for holistic interdisciplinary management approaches.
journal_name
Prim Care Diabetesjournal_title
Primary care diabetesauthors
Dzida G,Karnieli E,Svendsen AL,Sølje KS,Hermanns N,SOLVE Study Group.doi
10.1016/j.pcd.2015.01.002subject
Has Abstractpub_date
2015-10-01 00:00:00pages
346-53issue
5eissn
1751-9918issn
1878-0210pii
S1751-9918(15)00003-0journal_volume
9pub_type
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journal_title：Primary care diabetes
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journal_title：Primary care diabetes
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pub_type： 杂志文章,多中心研究
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journal_title：Primary care diabetes
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