Abstract:
AIM:To investigate if micro- and macrovascular co-morbidity has an influence on the time to insulin initiation in type 2 diabetes patients. METHODS:Longitudinal data from general practices in Germany, France and UK (Disease Analyzer) from 1995 to 2009 were analyzed, including 44,440 patients in Germany, 10,148 patients in France, and 25,499 patients in UK with newly diagnosed diabetes (index date). Cox regression was used to investigate the association of newly diagnosed micro- and macrovascular complications (ICD-10) on the time to insulin initiation adjusting for age, sex, antidiabetic therapy, and co-morbidity (hypertension, lipid disorders). RESULTS:Insulin treatment was started in 9747 (22%) patients in Germany within 10 years after index date (France: n=702, 7%; UK: 3936, 14%). In all three countries, occurrence of microvascular complications was significantly associated with a higher likelihood to have insulin initiated (hazard ratio (HR), 95%CI: neuropathy: Germany 1.6; 1.5-1.8; France: 2.1; 1.1-3.9; UK: 1.5; 1.3-1.9; nephropathy: Germany 1.4; 1.3-1.6; France: 2.7; 1.4-3.8; UK: 1.2; 1.1-1.3). Among macrovascular complications, only coronary heart disease was related to insulin initiation in all three countries (Germany 1.2; 1.1-1.3; France: 1.5; 1.2-2.0; UK: 1.5; 1.3-1.7). CONCLUSIONS:A more rapid progression to insulin therapy was found in patients with microvascular complications.
journal_name
Prim Care Diabetesjournal_title
Primary care diabetesauthors
Kostev K,Rathmann Wdoi
10.1016/j.pcd.2013.02.001subject
Has Abstractpub_date
2013-07-01 00:00:00pages
167-71issue
2eissn
1751-9918issn
1878-0210pii
S1751-9918(13)00027-2journal_volume
7pub_type
杂志文章,多中心研究abstract:AIMS:The purpose of our investigation was to identify the genetic and clinical risk factors of type 2 diabetes mellitus (T2DM) and to predict the incidence of T2DM in Korean adults aged 40-69 at follow-up intervals of 5, 7, and 10years. METHODS:Korean Genome and Epidemiology Study (KoGES) cohort data (n=10,030) were u...
journal_title:Primary care diabetes
pub_type: 杂志文章
doi:10.1016/j.pcd.2018.07.004
更新日期:2019-02-01 00:00:00
abstract:AIMS:To analyze the use of pain medication among community-dwelling people aged 65 years or older with and without type 2 diabetes in primary care. METHODS:A total of 187 patients with and 176 patients without diabetes were randomly selected from a primary care sample of 389 patients with diabetes and 604 age- and gen...
journal_title:Primary care diabetes
pub_type: 杂志文章
doi:10.1016/j.pcd.2020.05.016
更新日期:2020-12-01 00:00:00
abstract:BACKGROUND:Diabetes is especially common in the United Arab Emirates. Its complications in patients residing in the region have yet to be fully explored. This study reports on foot problems in our diabetic patients, with emphasis on the impact of illiteracy on foot care and complications due to diabetes. METHODS:Adult...
journal_title:Primary care diabetes
pub_type: 杂志文章
doi:10.1016/j.pcd.2015.04.008
更新日期:2015-12-01 00:00:00
abstract:AIM:To compare the prevalence of psychological distress and mental disorders between diabetes and non-diabetes sufferers and to identify associated factors. METHODS:Case-control study based on data from the 2006 to 2007 Spanish National Health Survey. We identified 2193 type 2 diabetic adults. Non-diabetic controls we...
journal_title:Primary care diabetes
pub_type: 杂志文章
doi:10.1016/j.pcd.2011.10.002
更新日期:2012-07-01 00:00:00
abstract:AIMS:To assess perceptions surrounding diabetes self-management (DSM) behaviors in Arab American patients with diabetes. METHODS:A 39-item survey was constructed from focus group discussions designed to better understand the impact of Arab American culture on DSM behaviors. The survey assessed perceptions about diet, ...
journal_title:Primary care diabetes
pub_type: 杂志文章
doi:10.1016/j.pcd.2019.09.002
更新日期:2020-06-01 00:00:00
abstract:OBJECTIVE:The objective of this observational open label trial was to characterize changes in diabetes self-management and psychological distress associated with a mobile health (mHealth) interactive voice response (IVR) self-management support program. METHODS:For 3-6 months, 301 patients with diabetes received weekl...
journal_title:Primary care diabetes
pub_type: 杂志文章
doi:10.1016/j.pcd.2014.06.003
更新日期:2015-04-01 00:00:00
abstract:OBJECTIVE:The aim of this research study was to ascertain the awareness of Maltese family doctors to the prevalence and significance of impaired glucose regulation and early diagnosis of type 2 diabetes and whether practices were influenced by employment status, post-graduate training in diabetes or years since graduat...
journal_title:Primary care diabetes
pub_type: 杂志文章
doi:10.1016/j.pcd.2013.12.003
更新日期:2014-10-01 00:00:00
abstract:AIMS:To assess differences in hemoglobin A1c (HbA1c) over time in diabetics treated by internal medicine physicians using the chronic care model (IMP-ancillary) or an advanced practice nurse (APN-IMP). METHODS:Retrospective, 2-group comparative design using administrative databases and matching of IMP-ancillary and AP...
journal_title:Primary care diabetes
pub_type: 杂志文章
doi:10.1016/j.pcd.2018.01.008
更新日期:2018-08-01 00:00:00
abstract:AIM:Among adults aged 20-45 years with type 2 diabetes mellitus, we examined the perceived quality of chronic care, and its associations with (i) sociodemographic and clinical characteristics, and (ii) diabetes distress. METHODS:In total, 216/460 (47%) completed a self-administered survey assessing sociodemographic ch...
journal_title:Primary care diabetes
pub_type: 杂志文章
doi:10.1016/j.pcd.2020.02.003
更新日期:2020-10-01 00:00:00
abstract:AIMS:The aim of this study was to evaluate the knowledge about GDM and its corresponding relation with glycaemic level in GDM patients. METHOD:A cross-sectional study was conducted in antenatal clinic of Hospital Pulau Pinang, Malaysia from June 2013 to December 2013 using Gestational Diabetes Mellitus Knowledge Quest...
journal_title:Primary care diabetes
pub_type: 杂志文章
doi:10.1016/j.pcd.2014.07.007
更新日期:2015-06-01 00:00:00
abstract::Seasonal variations in fasting glucose and HbA1c levels in 638 diabetic patients (attending a primary care diabetic clinic during 2003-2007) were examined and found to be significantly higher in colder than in warmer months. Moreover, there were apparent peaks in fasting glucose levels after Christmas and Easter month...
journal_title:Primary care diabetes
pub_type: 杂志文章
doi:10.1016/j.pcd.2009.05.004
更新日期:2009-05-01 00:00:00
abstract:AIMS:This study aimed to characterize and estimate prevalence and frequency of mild to moderate hypoglycemia and potentially associated factors in a population of type 2 diabetes mellitus (T2DM) patients treated at ambulatory care level. METHODS:HIPOS-PHARMA was a nationwide observational, cross-sectional, multicenter...
journal_title:Primary care diabetes
pub_type: 杂志文章,多中心研究
doi:10.1016/j.pcd.2018.06.001
更新日期:2018-12-01 00:00:00
abstract:AIMS:Incidence of type 1 diabetes mellitus (T1DM) is increasing worldwide. We aimed to study trends in presentation and incidence of childhood diabetes in the last 15years in south-western Iran. METHODS:During a detailed review of compiled records of the main tertiary children's hospital of southwest of Iran, from Jan...
journal_title:Primary care diabetes
pub_type: 杂志文章
doi:10.1016/j.pcd.2018.07.013
更新日期:2019-02-01 00:00:00
abstract:AIM:To investigate the effect of the BATHE therapeutic interview technique on the empowerment of diabetes mellitus patients in primary care. METHOD:A cluster randomised controlled study using the BATHE interview technique was conducted on diabetes mellitus patients in primary care. Physicians in the intervention group...
journal_title:Primary care diabetes
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.pcd.2016.12.003
更新日期:2017-04-01 00:00:00
abstract:PURPOSE:The aim of this study was to analyze the mortality trends of diabetes mellitus in Serbia (excluding the Autonomous Province of Kosovo and Metohia). METHODS:A population-based cross sectional study analyzing diabetes mortality in Serbia in the period 1991-2015 was carried out based on official data. The age-sta...
journal_title:Primary care diabetes
pub_type: 杂志文章
doi:10.1016/j.pcd.2016.08.019
更新日期:2017-02-01 00:00:00
abstract:AIMS:To identify risk factors for falls in older people with diabetes mellitus (DM) and to develop a low-cost fall risk screening tool. METHODS:Older adults with DM (n = 103; age = 61.6 + 6.0 years) were recruited from diabetic clinics. Demographic, DM specific factors, lower limb strength and sensation, cognition, fe...
journal_title:Primary care diabetes
pub_type: 杂志文章
doi:10.1016/j.pcd.2020.05.006
更新日期:2020-12-01 00:00:00
abstract:AIMS:Raising awareness of diabetic retinopathy (DR) was shown to be a key element for early diagnosis and treatment of this blinding disease. There is very limited data about the knowledge level, attitude, and behavior of diabetic patients regarding DR in Turkey. This study was planned to assess the awareness of DR and...
journal_title:Primary care diabetes
pub_type: 杂志文章
doi:10.1016/j.pcd.2013.04.002
更新日期:2013-12-01 00:00:00
abstract:AIMS:This study investigated (factors related to) (a) the response to a screening procedure for depression and anxiety in people with type 2 diabetes in primary care, and (b) participation in a subsequent randomised controlled trial targeting depressive or anxiety symptoms. METHODS:People with type 2 diabetes (n=1837)...
journal_title:Primary care diabetes
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.pcd.2017.02.006
更新日期:2017-06-01 00:00:00
abstract::Diabetes mellitus (DM) is a frequent disorder affecting individuals of all ages. Glycohemoglobin (GHb) has a key role in the assessment of glycemic control in diabetic patients. Generally, GHb is measured as hemoglobin (Hb) A1C and is the result of an irreversible non-enzymatic glycation of the beta chain of hemoglobi...
journal_title:Primary care diabetes
pub_type: 杂志文章,评审
doi:10.1016/j.pcd.2007.07.004
更新日期:2007-09-01 00:00:00
abstract:AIMS:Early age at menopause has been associated with increased incidence of type 2 diabetes mellitus (T2DM), but the quantitative association between age at menopause and T2DM was unclear. We performed a meta-analysis to assess the dose-response association between age at menopause and T2DM. METHODS:PubMed, Embase and...
journal_title:Primary care diabetes
pub_type: 杂志文章,meta分析
doi:10.1016/j.pcd.2019.02.001
更新日期:2019-08-01 00:00:00
abstract:OBJECTIVE:To examine the prevalence of chronic kidney disease (CKD) and related cardiovascular morbidity in a cross-sectional population in patients with type 2 diabetes (T2D) treated in a primary care setting in Finland. RESEARCH DESIGN AND METHODS:Data were collected and recorded from 42 primary care centres, which ...
journal_title:Primary care diabetes
pub_type: 杂志文章
doi:10.1016/j.pcd.2014.06.001
更新日期:2015-02-01 00:00:00
abstract:AIMS:People with diabetes have heightened levels of depressive symptoms, but less is known about the development of these symptoms in relation to diabetes duration. In this study, we examined the use of prescribed antidepressants in the first five years after diagnosis of diabetes among the working-age population in De...
journal_title:Primary care diabetes
pub_type: 杂志文章
doi:10.1016/j.pcd.2018.01.002
更新日期:2018-08-01 00:00:00
abstract::This review reported that coronavirus disease 2019 (COVID-19) infected patients with short time bed rest or quarantine and airway inflammation are at more risk of developing hyperglycemia and insulin resistance. This condition can induce oxidative stress, decrease immune system function, impair endothelial function, i...
journal_title:Primary care diabetes
pub_type: 杂志文章,评审
doi:10.1016/j.pcd.2021.01.002
更新日期:2021-01-09 00:00:00
abstract:AIMS:To describe the diabetic population receiving primary care from the Tshwane district public health services and to assess the quality of care of members of this population, their level of disease control and the extent of their complications. METHODS:A cluster-randomised trial was conducted in 12 primary care cli...
journal_title:Primary care diabetes
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.pcd.2014.05.002
更新日期:2015-04-01 00:00:00
abstract::Exenatide use in type 2 diabetes is limited in routine clinical practice. We examined a cross-section of 90 patients. Mean weight and HBA(1c) were 114.9+/-20.6 kg, 10.3+/-2.1% at initiation; 108.0+/-15.3 kg (p<0.0001), 9.0+/-2.1% (p<0.001) at 3 months; 109.2+/-18.2 kg (p<0.0001), 9.5+/-2.3% (p=0.08) at 6 months. Exena...
journal_title:Primary care diabetes
pub_type: 杂志文章
doi:10.1016/j.pcd.2009.11.001
更新日期:2010-04-01 00:00:00
abstract:AIMS:To investigate whether long-term mortality or clinical outcomes differed between patients diagnosed with type 2 diabetes mellitus and presenting with HbA1c within or above normal range at time of diagnosis. METHODS:Data were from a population-based sample of 1136 individuals with newly diagnosed type 2 diabetes m...
journal_title:Primary care diabetes
pub_type: 杂志文章
doi:10.1016/j.pcd.2012.09.001
更新日期:2013-04-01 00:00:00
abstract::Blood pressure management guidelines are widely available. Our aim was to examine differences in blood pressure on the same subjects in primary and secondary care. We identified 661 diabetic subjects with measurements with the aid of the SAIL databank. Blood pressure in primary care was significantly lower than second...
journal_title:Primary care diabetes
pub_type: 杂志文章
doi:10.1016/j.pcd.2009.06.001
更新日期:2009-08-01 00:00:00
abstract:AIM:We estimated the prevalence of undiagnosed diabetes, analyzed the influence of family history on the occurrence of T2D and evaluated its aggregation pattern in the Mauritanian population. METHODS:The prevalence of unknown diabetes was obtained using data compiled from 1278 Mauritanian adults applying a questionnai...
journal_title:Primary care diabetes
pub_type: 杂志文章
doi:10.1016/j.pcd.2012.12.002
更新日期:2013-04-01 00:00:00
abstract:AIMS:This study investigates whether diabetes patients visiting a primary care setting are interested in using a telemonitoring platform and if so, whether characteristics of interested users could be distinguished. METHODS:Three questionnaires were administered by 92 diabetes persons recruited between May and Septemb...
journal_title:Primary care diabetes
pub_type: 杂志文章
doi:10.1016/j.pcd.2012.10.085
更新日期:2013-07-01 00:00:00
abstract:AIM:The aim of the study was to determine factors influencing foot care behaviors among adults with type 2 diabetes. METHODS:A correlational descriptive study was conducted with a random sample of 160 adults with type 2 diabetes from the public hospital between April and July 2014. RESULTS:Just over 15% of the sample...
journal_title:Primary care diabetes
pub_type: 杂志文章
doi:10.1016/j.pcd.2016.04.002
更新日期:2016-12-01 00:00:00