Abstract：
AIMS:Chronic low-grade inflammation is closely linked to the development and progression of type 2 diabetes mellitus (T2DM). Since inflammatory markers tend to be chronically elevated in current smokers, we examined the association of inflammatory markers, including leukocyte counts and C-reactive protein (CRP) levels, with incidence risk of T2DM in non-smoking adults. METHODS:5568 non-smoking participants aged 40-69 years without diabetes at baseline were selected from the Korean Genome and Epidemiology Study (KoGES), a large prospective cohort study. The hazard ratios (HRs) with 95% confidence intervals (CIs) for incident T2DM according to leukocyte and CRP quartiles, respectively, were calculated using multivariate Cox proportional hazards regression models. RESULTS:During the 12-year follow-up period, T2DM developed in 1030 subjects (18.5%, 1030/5568), with an incidence rate of 3.1-4.9 per 2 years. The cumulative incidence of T2DM increased proportionally with increasing leukocyte and CRP quartiles. Compared with the reference first quartile, the HRs of incident T2DM in the second, third, and fourth quartiles of leukocyte counts and third and fourth quartiles of CRP levels increased in a dose-dependent manner after adjusting for potentially confounding variables. CONCLUSIONS:Leukocyte counts and CRP levels are predictors of incident T2DM independent of tobacco smoking.
journal_name
Prim Care Diabetesjournal_title
Primary care diabetesauthors
Cho AR,Lee JH,Lee HS,Lee YJdoi
10.1016/j.pcd.2020.11.010subject
Has Abstractpub_date
2020-12-03 00:00:00eissn
1751-9918issn
1878-0210pii
S1751-9918(20)30326-0pub_type
杂志文章abstract：AIMS:The aim of this study was to evaluate the knowledge about GDM and its corresponding relation with glycaemic level in GDM patients. METHOD:A cross-sectional study was conducted in antenatal clinic of Hospital Pulau Pinang, Malaysia from June 2013 to December 2013 using Gestational Diabetes Mellitus Knowledge Quest...
journal_title：Primary care diabetes
pub_type： 杂志文章
doi：10.1016/j.pcd.2014.07.007
更新日期：2015-06-01 00:00:00
abstract：BACKGROUND AND PURPOSE:Prediction algorithms are increasingly advocated in diabetes screening strategies, particularly in developing countries. We conducted a systematic review to assess the application and applicability of existing non-invasive prevalent diabetes risk models to populations within Africa. DESIGN:syste...
journal_title：Primary care diabetes
pub_type： 杂志文章,评审
doi：10.1016/j.pcd.2015.04.004
更新日期：2015-10-01 00:00:00
abstract：AIMS:This study investigates whether diabetes patients visiting a primary care setting are interested in using a telemonitoring platform and if so, whether characteristics of interested users could be distinguished. METHODS:Three questionnaires were administered by 92 diabetes persons recruited between May and Septemb...
journal_title：Primary care diabetes
pub_type： 杂志文章
doi：10.1016/j.pcd.2012.10.085
更新日期：2013-07-01 00:00:00
abstract：BACKGROUND:The incidence of type 2 diabetes (T2DM) is increasing. Having a pregnancy complicated by gestational diabetes mellitus (GDM) is a potent risk factor for the later development of T2DM. AIMS:To explore the characteristics of women diagnosed with GDM in a single centre and their follow up for progression to T2...
journal_title：Primary care diabetes
pub_type： 杂志文章
doi：10.1016/j.pcd.2020.05.010
更新日期：2020-12-01 00:00:00
abstract：AIMS:The goal of this retrospective cohort study was to analyze the incidence of, and factors associated with the antiepileptic drug (AED) therapy in the five years following the diagnosis of diabetic polyneuropathy in patients followed in Germany. METHODS:The study included patients aged 18-80 years with an initial d...
journal_title：Primary care diabetes
pub_type： 杂志文章
doi：10.1016/j.pcd.2020.12.005
更新日期：2021-01-06 00:00:00
abstract：AIM:We estimated the prevalence of undiagnosed diabetes, analyzed the influence of family history on the occurrence of T2D and evaluated its aggregation pattern in the Mauritanian population. METHODS:The prevalence of unknown diabetes was obtained using data compiled from 1278 Mauritanian adults applying a questionnai...
journal_title：Primary care diabetes
pub_type： 杂志文章
doi：10.1016/j.pcd.2012.12.002
更新日期：2013-04-01 00:00:00
abstract：OBJECTIVES:Novel interventions are needed for long-term maintenance of diabetes control. We studied the effects of a group diabetes clinic (GDC) on diabetes control when compared to usual care with primary care providers (PCP). RESEARCH DESIGN/METHODS:Data from the electronic medical records of 56 patients were collec...
journal_title：Primary care diabetes
pub_type： 杂志文章
doi：10.1016/j.pcd.2010.09.004
更新日期：2010-12-01 00:00:00
abstract：:Blood pressure management guidelines are widely available. Our aim was to examine differences in blood pressure on the same subjects in primary and secondary care. We identified 661 diabetic subjects with measurements with the aid of the SAIL databank. Blood pressure in primary care was significantly lower than second...
journal_title：Primary care diabetes
pub_type： 杂志文章
doi：10.1016/j.pcd.2009.06.001
更新日期：2009-08-01 00:00:00
abstract：AIM:The aim of this study was to evaluate the effect of diabetes education and short message service reminders on metabolic control and disease management in patients with type 2 diabetes mellitus who were registered in a family health center and who were using oral antidiabetics. METHODS:This pre-test and post-test c...
journal_title：Primary care diabetes
pub_type： 杂志文章
doi：10.1016/j.pcd.2020.04.007
更新日期：2020-10-01 00:00:00
abstract：AIMS:The purpose of our investigation was to identify the genetic and clinical risk factors of type 2 diabetes mellitus (T2DM) and to predict the incidence of T2DM in Korean adults aged 40-69 at follow-up intervals of 5, 7, and 10years. METHODS:Korean Genome and Epidemiology Study (KoGES) cohort data (n=10,030) were u...
journal_title：Primary care diabetes
pub_type： 杂志文章
doi：10.1016/j.pcd.2018.07.004
更新日期：2019-02-01 00:00:00
abstract：OBJECTIVE:The aim of this research study was to ascertain the awareness of Maltese family doctors to the prevalence and significance of impaired glucose regulation and early diagnosis of type 2 diabetes and whether practices were influenced by employment status, post-graduate training in diabetes or years since graduat...
journal_title：Primary care diabetes
pub_type： 杂志文章
doi：10.1016/j.pcd.2013.12.003
更新日期：2014-10-01 00:00:00
abstract：AIMS:To evaluate the incidence and risk factors for carotid artery stenosis amongst asymptomatic type 2 diabetes from a single Malaysian tertiary institution. METHODS:This is a prospective cross-sectional study of asymptomatic type 2 diabetics selected from the outpatient ophthalmology and endocrine clinics for caroti...
journal_title：Primary care diabetes
pub_type： 杂志文章
doi：10.1016/j.pcd.2019.10.001
更新日期：2020-08-01 00:00:00
abstract：:Our study demonstrates that Ipswich Touch Test is reliable and comparable to established standardized tests that identify the risk of foot ulceration among Saudi patients with diabetes mellitus. The simplicity of the test will assist in overcoming the barriers to screen for and detect the risk of foot ulceration. ...
journal_title：Primary care diabetes
pub_type： 杂志文章
doi：10.1016/j.pcd.2014.10.007
更新日期：2015-08-01 00:00:00
abstract：AIM:To identify risk factors of diabetic retinopathy (DR) among people with Type 2 diabetes mellitus in UK primary care. METHODS:A case-control study nested in a cohort of incident Type 2 diabetes identified in The Health Improvement Network database from 2000 to 2007. Cases were people with DR (N=7735) and controls w...
journal_title：Primary care diabetes
pub_type： 杂志文章
doi：10.1016/j.pcd.2016.01.002
更新日期：2016-08-01 00:00:00
abstract：AIMS:This study investigated (factors related to) (a) the response to a screening procedure for depression and anxiety in people with type 2 diabetes in primary care, and (b) participation in a subsequent randomised controlled trial targeting depressive or anxiety symptoms. METHODS:People with type 2 diabetes (n=1837)...
journal_title：Primary care diabetes
pub_type： 杂志文章,随机对照试验
doi：10.1016/j.pcd.2017.02.006
更新日期：2017-06-01 00:00:00
abstract：AIM:Depression is prevalent in patients with type 2 diabetes. It may have a negative impact on the management of diabetes mellitus and could affect weight. The main aim of the investigation was to evaluate the effect of antidepressant treatment (sertraline) on anthropometric variables and glycemic control in depressed ...
journal_title：Primary care diabetes
pub_type： 临床试验,杂志文章
doi：10.1016/j.pcd.2018.09.003
更新日期：2019-02-01 00:00:00
abstract：AIMS:To identify factors associated with patients receiving foot examinations by primary health care nurses. METHODS:A cross-sectional survey of 287 randomly sampled primary health care nurses, from a total of 1091 in Auckland, completed a postal self-administered questionnaire and telephone interview. Biographical an...
journal_title：Primary care diabetes
pub_type： 杂志文章
doi：10.1016/j.pcd.2013.10.002
更新日期：2014-07-01 00:00:00
abstract：:Insulin detemir provides prolonged, reproducible blood glucose reduction through a mechanism unique among basal insulins. It was originally studied clinically in predominantly basal + bolus regimens and found to be associated with a low risk of hypoglycaemia compared to insulin NPH, and reduced weight gain compared to...
journal_title：Primary care diabetes
pub_type： 历史文章,杂志文章
doi：10.1016/S1751-9918(10)60007-1
更新日期：2010-04-01 00:00:00
abstract：OBJECTIVE:The previous study served impaired fasting glucose (IFG), a pre-diabetic state which was much greater than that of diabetic patients, have reached no consensus on its cut-off value. In this study, we aimed to explore the cut-off value of IFG via the associations of blood lipids with fasting plasma glucose (FP...
journal_title：Primary care diabetes
pub_type： 杂志文章
doi：10.1016/j.pcd.2019.07.004
更新日期：2020-04-01 00:00:00
abstract：AIMS:To evaluate the health-related quality of life (HRQoL) and functional capacity in relation to glycemic control among older home-dwelling primary care patients. METHODS:Electronic patient records were used to identify 527 people over 65 years with diabetes. Of these, 259 randomly selected subjects were invited to ...
journal_title：Primary care diabetes
pub_type： 杂志文章
doi：10.1016/j.pcd.2017.07.001
更新日期：2017-12-01 00:00:00
abstract：AIM:To investigate the organisation of diabetes care in general practice in Ireland and identify areas for future development. METHODS:Survey of a representative sample of 600 general practitioners (GPs). The questionnaire contained closed and open-ended questions addressing 4 topics; characteristics of the practice, ...
journal_title：Primary care diabetes
pub_type： 杂志文章
doi：10.1016/j.pcd.2009.09.002
更新日期：2009-11-01 00:00:00
abstract：AIMS:To assess perceptions surrounding diabetes self-management (DSM) behaviors in Arab American patients with diabetes. METHODS:A 39-item survey was constructed from focus group discussions designed to better understand the impact of Arab American culture on DSM behaviors. The survey assessed perceptions about diet, ...
journal_title：Primary care diabetes
pub_type： 杂志文章
doi：10.1016/j.pcd.2019.09.002
更新日期：2020-06-01 00:00:00
abstract：AIMS:To identify risk factors for falls in older people with diabetes mellitus (DM) and to develop a low-cost fall risk screening tool. METHODS:Older adults with DM (n = 103; age = 61.6 + 6.0 years) were recruited from diabetic clinics. Demographic, DM specific factors, lower limb strength and sensation, cognition, fe...
journal_title：Primary care diabetes
pub_type： 杂志文章
doi：10.1016/j.pcd.2020.05.006
更新日期：2020-12-01 00:00:00
abstract：OBJECTIVE:Realise a review of studies of economic evaluation about the ambulatory monitoring of capillary glucose (AMGC) in diabetic type II persons. METHODOLOGY:A review of the literature was conducted, in MedLine, various websites, referenced paper and provided by expert's persons. RESULTS:Five studies concluded th...
journal_title：Primary care diabetes
pub_type： 杂志文章,评审
doi：10.1016/j.pcd.2013.11.005
更新日期：2014-04-01 00:00:00
abstract：AIMS:Early age at menopause has been associated with increased incidence of type 2 diabetes mellitus (T2DM), but the quantitative association between age at menopause and T2DM was unclear. We performed a meta-analysis to assess the dose-response association between age at menopause and T2DM. METHODS:PubMed, Embase and...
journal_title：Primary care diabetes
pub_type： 杂志文章,meta分析
doi：10.1016/j.pcd.2019.02.001
更新日期：2019-08-01 00:00:00
abstract：AIMS:To assess the diagnostic accuracy of the Finnish Diabetes Risk Score (FINDRISC) for undiagnosed T2DM and to compare its performance with the Latin-American FINDRISC (LA-FINDRISC) and the Peruvian Risk Score. MATERIALS AND METHODS:A population-based study was conducted. T2DM and undiagnosed T2DM were defined using...
journal_title：Primary care diabetes
pub_type： 杂志文章
doi：10.1016/j.pcd.2018.07.015
更新日期：2018-12-01 00:00:00
abstract：:Several cases of positive real time-polymerase chain reaction (RT-PCR) results (called "re-positives") after recovery from COVID-19 have emerged worldwide. These cases could represent patients experiencing a "turn positive" of nucleic acid detection attributed to the high false-negative rate of RT-PCR. On the contrary...
journal_title：Primary care diabetes
pub_type： 杂志文章,评审
doi：10.1016/j.pcd.2020.08.002
更新日期：2021-02-01 00:00:00
abstract：AIM:The aim of the study was to determine factors influencing foot care behaviors among adults with type 2 diabetes. METHODS:A correlational descriptive study was conducted with a random sample of 160 adults with type 2 diabetes from the public hospital between April and July 2014. RESULTS:Just over 15% of the sample...
journal_title：Primary care diabetes
pub_type： 杂志文章
doi：10.1016/j.pcd.2016.04.002
更新日期：2016-12-01 00:00:00
abstract：AIM:To compare once- versus twice-daily insulin detemir added on OADS therapy in insulin-naive type 2 diabetes patients in terms of efficacy and safety. METHODS:An open-label study performed at a single center, comprised a randomized, crossover 24 week with insulin-naive type 2 diabetes patients. Insulin detemir was i...
journal_title：Primary care diabetes
pub_type： 杂志文章,随机对照试验
doi：10.1016/j.pcd.2014.01.010
更新日期：2014-10-01 00:00:00
abstract：AIMS:Raising awareness of diabetic retinopathy (DR) was shown to be a key element for early diagnosis and treatment of this blinding disease. There is very limited data about the knowledge level, attitude, and behavior of diabetic patients regarding DR in Turkey. This study was planned to assess the awareness of DR and...
journal_title：Primary care diabetes
pub_type： 杂志文章
doi：10.1016/j.pcd.2013.04.002
更新日期：2013-12-01 00:00:00
