Abstract:
:Insulin detemir provides prolonged, reproducible blood glucose reduction through a mechanism unique among basal insulins. It was originally studied clinically in predominantly basal + bolus regimens and found to be associated with a low risk of hypoglycaemia compared to insulin NPH, and reduced weight gain compared to other basal insulins. Insulin detemir has been increasingly studied in basal-only insulin regimens in type 2 diabetes, in which an understanding of how to optimize its use has been built incrementally. Glycaemic control and limitation of weight gain tend to be maximized by once-daily (evening) dosing, earlier initiation and careful titration to appropriate fasting glucose targets.
journal_name
Prim Care Diabetesjournal_title
Primary care diabetesauthors
Meneghini L,Liebl A,Abrahamson MJdoi
10.1016/S1751-9918(10)60007-1subject
Has Abstractpub_date
2010-04-01 00:00:00pages
S31-42eissn
1751-9918issn
1878-0210pii
S1751-9918(10)60007-1journal_volume
4 Suppl 1pub_type
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journal_title:Primary care diabetes
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journal_title:Primary care diabetes
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journal_title:Primary care diabetes
pub_type: 杂志文章,多中心研究
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journal_title:Primary care diabetes
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journal_title:Primary care diabetes
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pub_type: 杂志文章,多中心研究
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journal_title:Primary care diabetes
pub_type: 杂志文章
doi:10.1016/j.pcd.2015.01.002
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pub_type: 杂志文章
doi:10.1016/j.pcd.2009.06.007
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pub_type: 杂志文章
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doi:10.1016/j.pcd.2009.05.004
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journal_title:Primary care diabetes
pub_type: 杂志文章
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journal_title:Primary care diabetes
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doi:10.1016/j.pcd.2020.02.003
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journal_title:Primary care diabetes
pub_type: 杂志文章
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更新日期:2011-12-01 00:00:00
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journal_title:Primary care diabetes
pub_type: 杂志文章
doi:10.1016/j.pcd.2013.01.002
更新日期:2013-04-01 00:00:00
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journal_title:Primary care diabetes
pub_type: 杂志文章
doi:10.1016/j.pcd.2018.04.002
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journal_title:Primary care diabetes
pub_type: 杂志文章,评审
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journal_title:Primary care diabetes
pub_type: 杂志文章
doi:10.1016/j.pcd.2015.04.008
更新日期:2015-12-01 00:00:00
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journal_title:Primary care diabetes
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.pcd.2017.02.006
更新日期:2017-06-01 00:00:00