Clusters of charged residues at the C terminus of MotA and N terminus of MotB are important for function of the Escherichia coli flagellar motor.

Abstract:

:MotA contains a conserved C-terminal cluster of negatively charged residues, and MotB contains a conserved N-terminal cluster of positively charged residues. Charge-altering mutations affecting these residues impair motility but do not diminish Mot protein levels. The motility defects are reversed by second-site mutations targeting the same or partner protein.

journal_name

J Bacteriol

journal_title

Journal of bacteriology

authors

Hosking ER,Manson MD

doi

10.1128/JB.00407-08

subject

Has Abstract

pub_date

2008-08-01 00:00:00

pages

5517-21

issue

15

eissn

0021-9193

issn

1098-5530

pii

JB.00407-08

journal_volume

190

pub_type

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