Abstract:
:Self-reactive lymphocytes form part of the peripheral repertoire in healthy individuals. Some of these cells are anergic classical lymphocytes, but a remarkable subset of self-reactive clones is related to innate immunity and many of them bear a partially activated phenotype. In the past few years growing evidence has pointed out the importance of this physiological autoimmunity in self tolerance, with special regard to the role of periportal innate lymphocytes. This population is involved in a wide range of immunoregulatory processes including immune privilege and oral tolerance, providing systemic tolerance to highly tissue-specific antigens as well as microbial epitopes cross-reactive to self. This kind of self-protection is dominantly mediated by self-reactive clones, which commonly play a dual role by acting as potent effectors and regulators at the same time. Here we provide an overview of the field.
journal_name
Autoimmun Revjournal_title
Autoimmunity reviewsauthors
Kristóf K,Erdei A,Bajtay Zdoi
10.1016/j.autrev.2007.10.002subject
Has Abstractpub_date
2008-02-01 00:00:00pages
278-83issue
4eissn
1568-9972issn
1873-0183pii
S1568-9972(07)00157-7journal_volume
7pub_type
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journal_title:Autoimmunity reviews
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journal_title:Autoimmunity reviews
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journal_title:Autoimmunity reviews
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journal_title:Autoimmunity reviews
pub_type: 杂志文章,评审
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更新日期:2005-09-01 00:00:00
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pub_type: 杂志文章,评审
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journal_title:Autoimmunity reviews
pub_type: 杂志文章,评审
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pub_type: 杂志文章,评审
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pub_type: 杂志文章
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更新日期:2014-10-01 00:00:00
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journal_title:Autoimmunity reviews
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journal_title:Autoimmunity reviews
pub_type: 杂志文章,评审
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journal_title:Autoimmunity reviews
pub_type: 杂志文章,评审
doi:10.1016/j.autrev.2007.01.012
更新日期:2007-08-01 00:00:00
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journal_title:Autoimmunity reviews
pub_type: 杂志文章,评审
doi:10.1016/j.autrev.2007.01.008
更新日期:2007-06-01 00:00:00
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journal_title:Autoimmunity reviews
pub_type: 杂志文章,评审
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更新日期:2018-09-01 00:00:00
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journal_title:Autoimmunity reviews
pub_type: 杂志文章,评审
doi:10.1016/j.autrev.2007.03.008
更新日期:2007-08-01 00:00:00
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journal_title:Autoimmunity reviews
pub_type: 杂志文章,评审
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更新日期:2015-12-01 00:00:00
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journal_title:Autoimmunity reviews
pub_type: 杂志文章,评审
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更新日期:2013-07-01 00:00:00
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journal_title:Autoimmunity reviews
pub_type: 杂志文章,评审
doi:10.1016/j.autrev.2011.04.005
更新日期:2011-07-01 00:00:00
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journal_title:Autoimmunity reviews
pub_type: 杂志文章,评审
doi:10.1016/j.autrev.2011.07.001
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journal_title:Autoimmunity reviews
pub_type: 杂志文章
doi:10.1016/j.autrev.2020.102612
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journal_title:Autoimmunity reviews
pub_type: 杂志文章,评审
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journal_title:Autoimmunity reviews
pub_type: 杂志文章,评审
doi:10.1016/j.autrev.2008.12.005
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journal_title:Autoimmunity reviews
pub_type: 杂志文章,评审
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journal_title:Autoimmunity reviews
pub_type: 杂志文章,评审
doi:10.1016/j.autrev.2011.01.005
更新日期:2011-05-01 00:00:00
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journal_title:Autoimmunity reviews
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doi:10.1016/j.autrev.2015.05.006
更新日期:2015-09-01 00:00:00
abstract:BACKGROUND:Ferritin and prolactin have been associated with active autoimmune diseases as systemic lupus erythematosus and autoantibody production, but have been little studied in viral infections that present autoimmunity. OBJECTIVE:To investigate the association of these two autoimmune mediators with the presence of...
journal_title:Autoimmunity reviews
pub_type: 杂志文章
doi:10.1016/j.autrev.2010.10.003
更新日期:2011-02-01 00:00:00
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journal_title:Autoimmunity reviews
pub_type: 杂志文章,评审
doi:10.1016/j.autrev.2005.08.009
更新日期:2006-02-01 00:00:00
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journal_title:Autoimmunity reviews
pub_type: 杂志文章,评审
doi:10.1016/j.autrev.2008.07.027
更新日期:2008-10-01 00:00:00
abstract::The "exposome" is a term recently used to describe all environmental factors, both exogenous and endogenous, which we are exposed to in a lifetime. It represents an important tool in the study of autoimmunity, complementing classical immunological research tools and cutting-edge genome wide association studies (GWAS)....
journal_title:Autoimmunity reviews
pub_type: 杂志文章,评审
doi:10.1016/j.autrev.2012.12.005
更新日期:2013-05-01 00:00:00
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journal_title:Autoimmunity reviews
pub_type: 杂志文章,评审
doi:10.1016/j.autrev.2007.12.003
更新日期:2008-02-01 00:00:00